The Effects Of 1 25 Dihydroxyvitamin D3 And Analogues On Uvb Irradiated Human Keratinocytes

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The Effects of 1,25-Dihydroxyvitamin D3 and Analogues on UVB-irradiated Human Keratinocytes

Author : Petra De Haes
Publisher : Leuven University Press
Page : 178 pages
File Size : 46,8 Mb
Release : 2004
Category : Keratinocytes
ISBN : 9058674282

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The Effects of 1,25-Dihydroxyvitamin D3 and Analogues on UVB-irradiated Human Keratinocytes by Petra De Haes Pdf

This is a Ph.D. dissertation. The skin serves as a protective interface between the body and the noxious environment. Ultraviolet (UV) radiation is one of the most important sources of environmental stress, inducing photochemical changes in the skin that may lead to sunburn, premature skin aging and skin cancer. The skin and UV also play a leading part in the vitamin D endocrine system. When UVB photons strike the epidermis, their energy can be used for the synthesis of vitamin D3. Furthermore, the skin is one of the direct target issues for vitamin D3 action. The close interplay between UV and vitamin D3 production in the skin evokes the possibility of mutual interactions. Contents: Introduction, Aims and Scopes of the Study, Materials and Methods, 1,25D3 Inhibits UVB-Induced Apoptosis and IL-6 Production in Human Keratinocytes, 1,25D3 Protects Human Keratinocytes Against UVB-Induced Damage, Two 14-EPI Analogues of 1,25D3 Protect Human Keratinocytes Against Different UVB Effects, Molecular Pathways Involved in the Anti-Apoptotic Effect of 1,25D3 in Human Keratinocytes, General Discussion and Perspectives.

Photoproduction of Vitamin D3 and Activation into 1a,25-Dihydroxyvitamin D3 in Human Epiderman Keratinocytes, Dermal Fibroblasts and Other Cells

Author : Katleen Vantieghem
Publisher : Leuven University Press
Page : 146 pages
File Size : 51,8 Mb
Release : 2006
Category : Keratinocytes
ISBN : 9058675610

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Photoproduction of Vitamin D3 and Activation into 1a,25-Dihydroxyvitamin D3 in Human Epiderman Keratinocytes, Dermal Fibroblasts and Other Cells by Katleen Vantieghem Pdf

The Protein-bound Solute P-cresol

Author : Bert Bammens
Publisher : Leuven University Press
Page : 276 pages
File Size : 51,8 Mb
Release : 2005
Category : Cresol
ISBN : 9058674827

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The Protein-bound Solute P-cresol by Bert Bammens Pdf

Between Facts and Norms

Author : Pascal Borry
Publisher : Leuven University Press
Page : 224 pages
File Size : 53,8 Mb
Release : 2005
Category : Bioethics
ISBN : 9058674940

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Between Facts and Norms by Pascal Borry Pdf

Neonatal Analgesia

Author : Karel Allegaert
Publisher : Leuven University Press
Page : 168 pages
File Size : 46,6 Mb
Release : 2005
Category : Pain in infants
ISBN : 905867505X

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Neonatal Analgesia by Karel Allegaert Pdf

Photodermatology

Author : Henry W. Lim,Herbert Honigsmann,John L. M. Hawk
Publisher : CRC Press
Page : 495 pages
File Size : 45,9 Mb
Release : 2007-02-01
Category : Medical
ISBN : 9781420019964

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Photodermatology by Henry W. Lim,Herbert Honigsmann,John L. M. Hawk Pdf

Covering the entire array of photodermatological topics necessary to stand at the head of this burgeoning discipline, this source contains expertly written chapters that offer recommendations and guidelines from opinion-forming international authorities. Reviewing the entire range of photodermatoses, as well as the management, treatment, i

Protein Phosphatase-1 Binding Motifs

Author : Paulina Wakula
Publisher : Leuven University Press
Page : 138 pages
File Size : 51,6 Mb
Release : 2006
Category : Science
ISBN : 9058675211

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Protein Phosphatase-1 Binding Motifs by Paulina Wakula Pdf

Increased Lipogenesis in Human Tumors

Author : Tine Van De Sande
Publisher : Leuven University Press
Page : 154 pages
File Size : 44,5 Mb
Release : 2004
Category : Cancer
ISBN : 905867438X

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Increased Lipogenesis in Human Tumors by Tine Van De Sande Pdf

This is a Ph.D. dissertation. The present thesis forms an integral part of the efforts to understand the molecular mechanisms and the biological and clinical significance of increased lipogenesis in tumor cells. In part I, it is explored whether the PI3-kinase/Akt pathway, a signal transduction cascade which is frequently dysregulated and constitutively activated in cancer cells, may contribute to increased lipogenesis. In part II, the authors have tried to gain more insight into the functional significance of tumor-associated lipogenesis by unraveling the nature and fate of newly synthesized lipids in cancer cells. To put these studies in a proper perspective, the authors will provide a more detailed overview of the present understanding of the mechanisms, the role and the clinical significance of increased lipogenesis in human cancer.

Sunlight, Vitamin D and Skin Cancer

Author : Jörg Reichrath
Publisher : Springer Nature
Page : 428 pages
File Size : 44,9 Mb
Release : 2020-09-11
Category : Medical
ISBN : 9783030462277

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Sunlight, Vitamin D and Skin Cancer by Jörg Reichrath Pdf

The third edition is a comprehensive and updated overview of positive and negative effects of UV-exposure, with a focus on Vitamin D and skin cancer. Researchers, oncologists,and students will be provided with the most significant and timely information related to topics such as the epidemiology of skin cancer, the immune system and skin cancer, ultraviolet damage, DNA repair and Vitamin D in Nonmelanoma skin cancer and malignant melanoma. There have been a number of new, scientific findings in this fast moving field that necessitated a thoroughly updated and revised edition including new Vitamin D metabolites and skin cancer, new findings on the beneficial effects of UV and solar UV and skin cancer, adverse effects of sun protection and sunscreens, sun exposure and mortality, and more. The book will summarize essential, up-to-date information for every clinician or scientist interested in how to balance the positive and negative effects of UV‐exposure to minimize the risks of developing vitamin D deficiency and skin cancer.