The Elucidation

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The Elucidation

Author : Albert Wilder Thompson
Publisher : Slatkine
Page : 138 pages
File Size : 55,7 Mb
Release : 1982
Category : Grail
ISBN : 2051004137

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The Elucidation by Albert Wilder Thompson Pdf

Analytical Techniques for the Elucidation of Protein Function

Author : Isao Suetake,Rohit K. Sharma,Hironobu Hojo
Publisher : John Wiley & Sons
Page : 245 pages
File Size : 43,5 Mb
Release : 2023-01-04
Category : Science
ISBN : 9781119886341

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Analytical Techniques for the Elucidation of Protein Function by Isao Suetake,Rohit K. Sharma,Hironobu Hojo Pdf

ANALYTICAL TECHNIQUES FOR THE ELUCIDATION OF PROTEIN FUNCTION An essential aid for scientists seeking alternative techniques for investigating proteins Proteins are the building blocks of living organisms, and they play an enormous range of fundamental roles in sustaining and shaping life. The critical determinant of a protein’s function is its structure, and the analysis of protein structures has therefore become a significant component of biological research. In recent years, longstanding analytical techniques such as X-ray crystallography and nuclear magnetic resonance (NMR) spectroscopy have been supplemented by a number of new methods which promise to revolutionize the study of proteins and their functions. Analytical Techniques for the Elucidation of Protein Function serves as an introduction to these techniques, which are especially crucial for analyzing intrinsically disordered regions and post-translational modifications. These have revolutionized the study of proteins in recent years, and conventional methods for analyzing protein structures are no longer sufficient to work through their ramifications. This book therefore brings greater awareness of techniques which promise to produce the very cutting edge of protein research. Analytical Techniques for the Elucidation of Protein Function readers will find: A discussion of techniques including electron paramagnetic resonance (ESR) spectroscopy, neutron scattering, Raman imaging, and more Both theoretical background and practical applications for each technique Contributions from leading international researchers into protein structure and function This practically focused text is a valuable reference for protein and peptide analysis and synthesis researchers, as well as for graduate and advanced undergraduate students in the life sciences.

Modern NMR Approaches to the Structure Elucidation of Natural Products

Author : Antony Williams,Gary Martin,David Rovnyak
Publisher : Royal Society of Chemistry
Page : 532 pages
File Size : 55,8 Mb
Release : 2016-12-14
Category : Science
ISBN : 9781849733939

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Modern NMR Approaches to the Structure Elucidation of Natural Products by Antony Williams,Gary Martin,David Rovnyak Pdf

The Ghanian plant Cryptolepis sanguinolenta is the source of a series of fascinating indoloquinoline alkaloids. The most unusual member of this alkaloid series was initially proposed to be a spiro nonacyclic structure, named cryptospirolepine, and was elucidated in 1993 based on the technologies available at that time. There were, however, several annoying attributes to the structure that bothered analysts for the ensuing 22 years. During the two decades that followed the initial work there have been enormous developments in NMR technology. Using new experimental approaches, specifically homodecoupled 1,1- and 1,n-HD-ADEQUATE NMR experiments developed in 2014, the structure of only a 700 µg sample of cryptospirolepine has been revised and is shown on the cover of this volume. The confluence of the NMR technological and methodological advances that allowed the revision of the structure of cryptospirolepine using a submilligram sample seems a fitting example for this book, which is dedicated to the NMR characterization of various classes of natural products. Volume 2 considers data processing and algorithmic based analyses tailored to natural product structure elucidation and reviews the application of NMR to the analysis of a series of different natural product families including marine natural products, terpenes, steroids, alkaloids and carbohydrates. Volume 1 discusses contemporary NMR approaches including optimized and future hardware and experimental approaches to obtain both the highest quality and most appropriate spectral data for analysis. These books, bringing together acknowledged experts, uniquely focus on the combination of experimental approaches and modern hardware and software applied to the structure elucidation of natural products. The volumes will be an essential resource for NMR spectroscopists, natural product chemists and industrial researchers working on natural product analysis or the characterization of impurities and degradation products of pharmaceuticals that can be as scarce as natural product samples.

Contemporary Computer-Assisted Approaches to Molecular Structure Elucidation

Author : Mikhail E Elyashberg,Antony Williams,Kirill Blinov
Publisher : Royal Society of Chemistry
Page : 504 pages
File Size : 54,5 Mb
Release : 2011-11-07
Category : Science
ISBN : 9781849734578

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Contemporary Computer-Assisted Approaches to Molecular Structure Elucidation by Mikhail E Elyashberg,Antony Williams,Kirill Blinov Pdf

Computer-Assisted Structure Elucidation (CASE) systems are a combination of software algorithms and tools to support and enable chemists and spectroscopists engaged in the process of molecular structure elucidation via the analysis of spectroscopic data. These expert systems dramatically reduce the time associated with structure elucidation and improve the reliability of the results. Contemporary Computer-Assisted Approaches to Molecular Structure Elucidation describes the principles on which these expert systems for spectroscopic structure elucidation are based and concisely explains the algorithmic concepts behind the programs. The authors use their own personal experiences in the development of the Structure Elucidator (StrucEluc) CASE software system to discuss the present state-of-the-art in computer-assisted structure elucidation. Scientists that are presently using CASE systems will be interested in the algorithms and modern approaches and for organizations that are currently using the StrucEluc platform the book is designed to help researchers understand the strategies behind CASE as well as details regarding the StrucEluc platform. For scientists that have never used CASE systems they will now have access to all necessary information to understand CASE systems for mastering this new and very effective approach to structure elucidation. The authors overall goal is writing this book is to produce the 'must read' definitive text that will represent the results of decades of work to develop computer-assisted structure elucidation software systems. CASE systems are now powerful software tools commonly outperforming and correcting human interpretations of data. This book will also provide an historical perspective of the work of the founding fathers of the technique and identify the challenges that have been overcome to produce modern CASE systems.

Sainik Samachar

Author : Anonim
Publisher : Unknown
Page : 948 pages
File Size : 53,6 Mb
Release : 1970
Category : India
ISBN : UIUC:30112043891198

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Structure Elucidation in Organic Chemistry

Author : Maria-Magdalena Cid,Jorge Bravo
Publisher : John Wiley & Sons
Page : 552 pages
File Size : 42,9 Mb
Release : 2015-01-05
Category : Science
ISBN : 9783527664634

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Structure Elucidation in Organic Chemistry by Maria-Magdalena Cid,Jorge Bravo Pdf

Intended for advanced readers, this is a review of all relevant techniques for structure analysis in one handy volume. As such, it provides the latest knowledge on spectroscopic and related techniques for chemical structure analysis, such as NMR, optical spectroscopy, mass spectrometry and X-ray crystallography, including the scope and limitation of each method. As a result, readers not only become acquainted with the techniques, but also the advantages of the synergy between them. This enables them to choose the correct analytical method for each problem, saving both time and resources. Special emphasis is placed on NMR and its application to absolute configuration determination and the analysis of molecular interactions. Adopting a practical point of view, the author team from academia and industry guarantees both solid methodology and applications essential for structure determination, equipping experts as well as newcomers with the tools to solve any structural problem.

The Columbian Cyclopedia

Author : Anonim
Publisher : Unknown
Page : 902 pages
File Size : 54,7 Mb
Release : 1897
Category : Encyclopedias and dictionaries
ISBN : MINN:31951002062711I

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The Columbian Cyclopedia by Anonim Pdf

Chambers's

Author : Anonim
Publisher : Unknown
Page : 870 pages
File Size : 47,7 Mb
Release : 1872
Category : Electronic
ISBN : UOMDLP:ajd6864:0001.001

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Chambers's by Anonim Pdf

Structure Elucidation by NMR in Organic Chemistry

Author : Eberhard Breitmaier
Publisher : John Wiley & Sons
Page : 279 pages
File Size : 52,9 Mb
Release : 2002-11-22
Category : Science
ISBN : 9780470850077

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Structure Elucidation by NMR in Organic Chemistry by Eberhard Breitmaier Pdf

This text provides the graduate student with a systematic guide to unravelling structural information from the NMR spectra of unknown synthetic and natural compounds. A brief introduction gives an overview of the basic principles and elementary instrumental methods of NMR. This is followed by instructional strategy and tactical advice on how to translate spectra into meaningful structural information. The book provides the student with 55 sets of spectra of graduated complexity. These are designed to challenge the student's problem-solving abilities by the introduction of new concepts with each group of problems, followed by possible solutions and full explanations. A formula index of solutions is provided at the end of the text. This third edition, following on from the second (a reprint of the first edition with corrections), presents significant new material. Thus, actual methods of two-dimensional NMR such as some inverse techniques of heteronuclear shift correlation, as well as the detection of proton-proton connectivities and nuclear Overhauser effects are included. To demonstrate the applications of these methods, new problems have replaced those of previous editions.

Chambers's Encyclopædia

Author : Anonim
Publisher : Unknown
Page : 870 pages
File Size : 55,6 Mb
Release : 1886
Category : Encyclopedias and dictionaries
ISBN : HARVARD:HN52KG

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Chambers's Encyclopædia by Anonim Pdf

Chambers's Encyclopedia

Author : william and robert
Publisher : Unknown
Page : 958 pages
File Size : 44,8 Mb
Release : 1874
Category : Electronic
ISBN : 8210379456XXX

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Chambers's Encyclopedia by william and robert Pdf

Company Law in East Asia

Author : Roman Tomasic
Publisher : Routledge
Page : 708 pages
File Size : 50,7 Mb
Release : 2018-08-13
Category : Law
ISBN : 9780429861536

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Company Law in East Asia by Roman Tomasic Pdf

First published in 1999, this volume provides an overview of company laws in South East Asia, North East Asia and the Pacific. The chapters adopt a standard format to allow for comparisons to be made as well as highlighting key features of company laws in each jurisdiction. The contributors are experts in their fields and present practical and policy related insights. The book also contains some useful overviews of company law themes in Asia.

The Adventures of the Panjáb Hero Rájá Rasálu

Author : Charles Swynnerton
Publisher : Unknown
Page : 296 pages
File Size : 52,8 Mb
Release : 1884
Category : Folklore
ISBN : UOM:39015058385546

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The Adventures of the Panjáb Hero Rájá Rasálu by Charles Swynnerton Pdf