The Endocrine Pancreas And Regulation Of Metabolism

Author : Leonard S. Jefferson,P. Michael Conn,H. Maurice Goodman,Alan D. Cherrington,Jack L. Kostyo
Publisher : Unknown
Page : 1254 pages
File Size : 40,6 Mb
Release : 2001-01
Category : Endocrine glands
ISBN : 0195113268

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The Endocrine System: The endocrine pancreas and regulation of metabolism by Leonard S. Jefferson,P. Michael Conn,H. Maurice Goodman,Alan D. Cherrington,Jack L. Kostyo Pdf

This comprehensive and authoritative reference work examines the role of the endocrine pancreas in the regulation of fat, protein, and carbohydrate metabolism. The effects of hormones are broadly examined with emphasis on the gene, the cell and the organism as a whole. The functions of the pancreatic hormones in the integrated response of the body to various physiologic challenges are discussed. Following a general introduction by Sir Philip Randle, the book is divided into four sections:1. The Islets of Langerhans, 2. Target Tissues for Metabolic Regulatory Hormones, 3. Influence of Hormones Acting as Acute Metabolic Regulators on the Actions of Islet Hormones, and 4. Integrated Hormonal Responses to Physiological Challenges. The fourth part covers many interesting conditions such as pregnancy, aging, obesity, hypoglycemia, insulin-dependent diabetes mellitus, and starvation.

Author : W. Montague
Publisher : Springer Science & Business Media
Page : 168 pages
File Size : 42,8 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789401163798

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Diabetes and the Endocrine Pancreas by W. Montague Pdf

This book attempts to explore the contribution that biochemistry has made, thus far, to our understanding of the endocrine pancreas and its relationship to diabetes mellitus. It was written with the aim of using an important clinical problem to illustrate, to medical students, that there are many aspects of the biochemistry taught in the early years which have direct relevance to clinical medicine. Furthermore, it is hoped that such information might provide biochemistry students with a frame work on which to base further studies. To this end a selection of recent references has been placed at the end of each chapter. In spite of considerable advances in our understanding of diabetes mellitus, it is still a disease which many physicians do not seem to com prehend. This is in part related to their lack of understanding of the molecular biology of the disease. Advances in this area have been dramatic in recent years and we are now able to offer a molecular basis for a rational approach to therapy. It may be therefore that this book will provide some physicians with the information they require to help them gain a deeper understanding of the disease. I hope that everyone who reads this book is able to capture some of the fascination that the islets of Langerhans hold for myself and the many other workers actively engaged in trying to unravel their mys teries.

Author : Ellis Samols
Publisher : Lippincott Williams & Wilkins
Page : 568 pages
File Size : 54,6 Mb
Release : 1991
Category : Diabetes
ISBN : UOM:39015019849929

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The Endocrine Pancreas by Ellis Samols Pdf

Author : David M. Klachko
Publisher : Springer Science & Business Media
Page : 209 pages
File Size : 41,6 Mb
Release : 2013-03-09
Category : Medical
ISBN : 9781468485080

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The Endocrine Pancreas and Juvenile Diabetes by David M. Klachko Pdf

Dr. Robert L. Jackson, Professor of Child Health at the Uni versity of Missouri-Columbia, decided to retire from clinical practice in 1977 and the Department of Child Health planned a con ference in his honor. The Thirteenth Annual MidweSt Conference on Endocrinology and Metabolism also was in the planning stages and scheduled for two days in the fall. It seemed appropriate to com bine the two into an expanded three-day conference. In view of Dr. Jackson's international reputation in the study and care of children with diabetes mellitus, the conference topic was not dif ficult to find. Experts in this field were delighted to be asked to speak at a conference in Dr. Jackson's honor. We selected a number of excellent speakers to survey the physiology and pathophy siology of pancreatic hormones and their effects in diabetes mel litus, to discuss current knowledge of the microvascular complica tions of the disease, and to put it all into the proper historical perspective of where we have been and where we are going. We think the conference achieved its objective to pay meaningful trib ute to a distinguished member of the scientific community. As with any conference, the conversion of the presentations and discussions to the printed page is a long and arduous process. Many manuscripts were completed well after the conference and references often are more recent than the date of the conference.

Author : S. Falkmer,B. Hellman,I.-B. Täljedal
Publisher : Elsevier
Page : 585 pages
File Size : 55,6 Mb
Release : 2013-10-22
Category : Science
ISBN : 9781483186627

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The Structure and Metabolism of the Pancreatic Islets by S. Falkmer,B. Hellman,I.-B. Täljedal Pdf

The Structure and Metabolism of the Pancreatic Islets: A Centennial of Paul Langerhans' Discovery is a collection of that presents the advancement in the field of pancreatic islet research, particularly in the area of biosynthesis and secretion of insulin. The title also serves as a commemorative material to Paul Langerhans' work. The text first covers the differentiation and growth of the endocrine pancreas, and then proceeds to tackling a- and ß-cells. Next, the selection deals with the glucose metabolism of the pancreatic islets. The text also discusses the biosynthesis and storage of insulin, along with insulin release. The seventh part details pancreatic islets and diabetes. The book will be of great use to students, researchers, and practitioners of medicine.

Author : J. Gordon Betts,Peter DeSaix,Jody E. Johnson,Oksana Korol,Dean H. Kruse,Brandon Poe,James A. Wise,Mark Womble,Kelly A. Young
Publisher : Unknown
Page : 0 pages
File Size : 51,7 Mb
Release : 2013-04-25
Category : Electronic
ISBN : 1947172808

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Anatomy and Physiology by J. Gordon Betts,Peter DeSaix,Jody E. Johnson,Oksana Korol,Dean H. Kruse,Brandon Poe,James A. Wise,Mark Womble,Kelly A. Young Pdf

Author : Leonard S. Jefferson
Publisher : Unknown
Page : 0 pages
File Size : 48,6 Mb
Release : 2001
Category : Endocrine glands
ISBN : 0195113268

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Handbook of Physiology by Leonard S. Jefferson Pdf

Author : David J. Hill
Publisher : Bentham Science Publishers
Page : 253 pages
File Size : 55,8 Mb
Release : 2016-12-02
Category : Science
ISBN : 9781681083650

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Control of Pancreatic Beta Cell Function and Plasticity in Health and Diabetes by David J. Hill Pdf

Plasticity in insulin-producing cells (β-cells) of the pancreas is a major contributor to metabolic control. Targeted regeneration of pancreatic β-cells for the reversal of diabetes (by optimizing β-cells mass and proliferation to meet metabolic requirements and counter autoimmune response) is still a theoretical intervention. This monograph reviews the biology, ontogeny, capabilities, and present practical limitations of β-cell plasticity. Relevant biochemical pathways are described with the inclusion of information about how they change with aging, during pregnancy, and with diet. Readers will learn the following key aspects about β-cell plasticity: -current knowledge of pancreatic β-cells development, and how β-cell mass and proliferation change throughout the human lifespan -the mechanisms responsible for β-cell plasticity, based on animal models and clinical studies revealing environmental, epigenetic, endocrine and paracrine regulators -the therapeutic potential of resident stem cells within the pancreas / bone marrow and β-cell progenitors This monograph is essential reading for researchers interested in updated knowledge about the molecular and cellular biology of β-cells in the quest to find a reliable therapy for diabetes.

Author : Sven Elov Brolin,Bo Hellman,H. Knutson
Publisher : Pergamon
Page : 554 pages
File Size : 46,8 Mb
Release : 1964
Category : Medical
ISBN : UOM:39015004396951

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The Structure and Metabolism of the Pancreatic Islets by Sven Elov Brolin,Bo Hellman,H. Knutson Pdf

Author : Robert L. Hazelwood
Publisher : Unknown
Page : 258 pages
File Size : 43,6 Mb
Release : 1989
Category : Islands of Langerhans.
ISBN : UOM:39015015056073

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The Endocrine Pancreas by Robert L. Hazelwood Pdf

Author : Pierre J. Lefèbvre
Publisher : Springer
Page : 356 pages
File Size : 40,6 Mb
Release : 1988
Category : Health & Fitness
ISBN : UOM:39015013200194

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The Pathology of the Endocrine Pancreas in Diabetes by Pierre J. Lefèbvre Pdf

Diabetes mellitus represents one of the most frequent and serious clinical syn dromes in contemporary medicine. Since the end of the nineteenth century, the endocrine pancreas has been implicated in the pathogenesis of this disease. Several pathologists of the twentieth century detected various lesions and mor phologic alterations in the pancreatic islets of diabetic patients, but the patho physiologic basis of their findings remained long obscure. The systematic mi croscopic work of WILLY GEPTS clarified the views and related the variety in histopathology to differences in origin, duration and clinical expression of the disease. Over the past two decades, the concept of a multifactorial origin of diabetes has become widely accepted. Various agents and mechanisms have been identified which can lead to a quantitative or qualitative deficit in pancre atic B-cells. The purpose of this book is to bring an update on the many path ways which may induce an absolute or relative insufficiency in insulin release and hence a diabetic state. Rather than bringing a complete account on all re search relevant to the understanding of the pathology of the diabetic pancreas, the authors of the various chapters of this volume have focussed on selected processes which can impair B-cell function, survival or regeneration.

Author : Antonino Belfiore,Derek LeRoith
Publisher : Springer
Page : 0 pages
File Size : 51,7 Mb
Release : 2018-02-08
Category : Medical
ISBN : 3319446746

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Principles of Endocrinology and Hormone Action by Antonino Belfiore,Derek LeRoith Pdf

This volume provides comprehensive coverage of the current knowledge of the physiology of the endocrine system and hormone synthesis and release, transport, and action at the molecular and cellular levels. It presents essential as well as in-depth information of value to both medical students and specialists in Endocrinology, Gynecology, Pediatrics, and Internal Medicine. Although it is well established that the endocrine system regulates essential functions involved in growth, reproduction, and homeostasis, it is increasingly being recognized that this complex regulatory system comprises not only hormones secreted by the classic endocrine glands but also hormones and regulatory factors produced by many organs, and involves extensive crosstalk with the neural and immune system. At the same time, our knowledge of the molecular basis of hormone action has greatly improved. Understanding this complexity of endocrine physiology is crucial to prevent endocrine disorders, to improve the sensitivity of our diagnostic tools, and to provide the rationale for pharmacological, immunological, or genetic interventions. It is such understanding that this book is designed to foster.

Author : Leonid Poretsky
Publisher : Springer Science & Business Media
Page : 764 pages
File Size : 44,8 Mb
Release : 2013-11-11
Category : Medical
ISBN : 9781475762600

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Principles of Diabetes Mellitus by Leonid Poretsky Pdf

Diabetes mellitus is a very common disease which affects approximately 150,000,000 worldwide. With its prevalence rising rapidly, diabetes continues to mystify and fascinate both practitioners and investigators by its elusive causes and multitude of This textbook is written for endocrinologists, specialists in other disciplines who treat diabetic patients, primary care physicians, housestaff and medical students. It covers, in a concise and clear manner, all aspects of the disease, from its pathogenesis on the molecular and cellular levels to its most modern therapy.

Author : Anonim
Publisher : Unknown
Page : 740 pages
File Size : 46,7 Mb
Release : 1972
Category : Electronic
ISBN : NWU:35558000008462

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Endocrine Pancreas by Anonim Pdf

Author : Keith N. Frayn
Publisher : Ashgate Publishing
Page : 288 pages
File Size : 49,9 Mb
Release : 1996
Category : Medical
ISBN : UOM:39015040671227

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Metabolic Regulation by Keith N. Frayn Pdf

In this volume, the subject of metabolic regulation is placed in a human context. The components of food are followed as they are processed from ingestion through digestion and absorption to their distribution to the tissues, storage and mobilization and ultimate oxidation. The way in which these processes are regulated by the endocrine and nervous systems is described, as well as the metabolic adjustments necessitated by extreme conditions such as fasting and strenuous exercise.