The Human Microbiota In Health And Disease

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Human Microbiota in Health and Disease

Bryan Tungland
Human Microbiota in Health and Disease Book PDF

Author : Bryan Tungland
Publisher : Academic Press
Page : 680 pages
File Size : 43,7 Mb
Release : 2018-05-25
Category : Science
ISBN : 9780128146507

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Human Microbiota in Health and Disease by Bryan Tungland Pdf

Human Gut Microbiota in Health and Disease: From Pathogenesis to Therapy is a comprehensive discussion on all the aspects associated with the early colonization of gut microbiota, its development and maintenance, and its symbiotic relationship with the host in promoting health. Chapters illustrate the complex mechanisms and metabolic signaling pathways related to how the gut microbiota maintain proper regulation of glucose, lipid and energy homeostasis and immune response, all while mediating inflammatory processes involved in the etiology of many chronic disease conditions. With today's common use of pharmaceutical medicine in treating symptoms and frequent overuse of antibiotics in chronic disease within mainstream medical practice, our understanding of the etiological mechanisms of dysbiosis-induced chronic disease and natural approaches to prevention and potential cures for these diseases is of vital importance to overall human health. Details the complex relationship between human microbiota in the gut, oral cavity and skin as well as their colonization, development and impact of factors that influence the relationship Illustrates the mechanisms associated with dysbiosis-associated inflammation and its role in the onset and progression in chronic disease Provides the primary mechanisms and comprehensive scientific evidence for the use of dietary modification and pro- and prebiotics in preventing chronic disease

The Human Microbiota in Health and Disease

Mike Wilson
The Human Microbiota in Health and Disease Book PDF

Author : Mike Wilson
Publisher : Garland Science
Page : 1043 pages
File Size : 52,5 Mb
Release : 2018-09-03
Category : Science
ISBN : 9781351068345

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The Human Microbiota in Health and Disease by Mike Wilson Pdf

A human being consists of a mammalian component and a multiplicity of microbes, collectively referred to as the "microbiota" or "microbiome," with which it has a symbiotic relationship. The microbiota is comprised of a variety of communities, the composition of each being dependent on the body site it inhabits. This community variation arises because the numerous locations on a human being provide very different environments, each of which favors the establishment of a distinct microbial community. Each community consists of bacteria, fungi and viruses with, in some cases, archaea and/or protozoa. It is increasingly being recognized that the indigenous microbiota plays an important role in maintaining the health of its human host. However, changes in the overall composition of a microbial community at a body site, or an increase in the proportion of a particular species in that community, can result in disease or other adverse consequences for the host. The Human Microbiota in Health and Disease: An Ecological and Community-Based Approach describes the nature of the various communities inhabiting humans as well as the important roles they play in human health and disease. It discusses techniques used to determine microbial community composition and features a chapter devoted to the many factors that underlie this mammalian–microbe symbiosis. Uniquely, the book adopts an ecological approach to examining the microbial community’s composition at a particular body site and why certain factors can shift a community from a eubiotic to a dysbiotic state. The book is for undergraduates and postgraduates on courses with a module on the indigenous microbiota of humans. It will also be useful to scientists, clinicians, and others seeking information on the human microbiota and its role in health and disease.

The Human Microbiota and Chronic Disease

Luigi Nibali,Brian Henderson
The Human Microbiota and Chronic Disease Book PDF

Author : Luigi Nibali,Brian Henderson
Publisher : John Wiley & Sons
Page : 564 pages
File Size : 46,8 Mb
Release : 2016-10-03
Category : Science
ISBN : 9781118982877

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The Human Microbiota and Chronic Disease by Luigi Nibali,Brian Henderson Pdf

Microbiota-associated pathology can be a direct result of changes in general bacterial composition, such as might be found in periodontitis and bacterial vaginosis, and/or as the result of colonization and/or overgrowth of so called keystone species. The disruption in the composition of the normal human microbiota, or dysbiosis, plays an integral role in human health and human disease. The Human Microbiota and Human Chronic Disease: Dysbioses as a Cause of Human Pathology discusses the role of the microbiota in maintaining human health. The text introduces the reader to the biology of microbial dysbiosis and its potential role in both bacterial disease and in idiopathic chronic disease states. Divided into five sections, the text delineates the concept of the human bacterial microbiota with particular attention being paid to the microbiotae of the gut, oral cavity and skin. A key methodology for exploring the microbiota, metagenomics, is also described. The book then shows the reader the cellular, molecular and genetic complexities of the bacterial microbiota, its myriad connections with the host and how these can maintain tissue homeostasis. Chapters then consider the role of dysbioses in human disease states, dealing with two of the commonest bacterial diseases of humanity – periodontitis and bacterial vaginosis. The composition of some, if not all microbiotas can be controlled by the diet and this is also dealt with in this section. The discussion moves on to the major ‘idiopathic’ diseases afflicting humans, and the potential role that dysbiosis could play in their induction and chronicity. The book then concludes with the therapeutic potential of manipulating the microbiota, introducing the concepts of probiotics, prebiotics and the administration of healthy human faeces (faecal microbiota transplantation), and then hypothesizes as to the future of medical treatment viewed from a microbiota-centric position. Provides an introduction to dysbiosis, or a disruption in the composition of the normal human microbiota Explains how microbiota-associated pathology and other chronic diseases can result from changes in general bacterial composition Explores the relationship humans have with their microbiota, and its significance in human health and disease Covers host genetic variants and their role in the composition of human microbial biofilms, integral to the relationship between human health and human disease Authored and edited by leaders in the field, The Human Microbiota and Human Chronic Disease will be an invaluable resource for clinicians, pathologists, immunologists, cell and molecular biologists, biochemists, and system biologists studying cellular and molecular bases of human diseases.

The Gut Microbiome in Health and Disease

Dirk Haller
The Gut Microbiome in Health and Disease Book PDF

Author : Dirk Haller
Publisher : Springer
Page : 356 pages
File Size : 44,6 Mb
Release : 2018-07-27
Category : Medical
ISBN : 9783319905457

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The Gut Microbiome in Health and Disease by Dirk Haller Pdf

The book provides an overview on how the gut microbiome contributes to human health. The readers will get profound knowledge on the connection between intestinal microbiota and immune defense systems. The tools of choice to study the ecology of these highly-specialized microorganism communities such as high-throughput sequencing and metagenomic mining will be presented. In addition the most common diseases associated to the composition of the gut flora are discussed in detail. The book will address researchers, clinicians and advanced students working in biomedicine, microbiology and immunology.

Microbiome in Human Health and Disease

Pallaval Veera Bramhachari
Microbiome in Human Health and Disease Book PDF

Author : Pallaval Veera Bramhachari
Publisher : Springer Nature
Page : 306 pages
File Size : 54,5 Mb
Release : 2021-10-18
Category : Medical
ISBN : 9789811631566

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Microbiome in Human Health and Disease by Pallaval Veera Bramhachari Pdf

The book provides an overview on how the microbiome contributes to human health and disease. The microbiome has also become a burgeoning field of research in medicine, agriculture & environment. The readers will obtain profound knowledge on the connection between intestinal microbiota and immune defense systems, medicine, agriculture & environment. The book may address several researchers, clinicians and scholars working in biomedicine, microbiology and immunology. The application of new technologies has no doubt revolutionized the research initiatives providing new insights into the dynamics of these complex microbial communities and their role in medicine, agriculture & environment shall be more emphasized. Drawing on broad range concepts of disciplines and model systems, this book primarily provides a conceptual framework for understanding these human-microbe, animal-microbe & plant-microbe, interactions while shedding critical light on the scientific challenges that lie ahead. Furthermore this book explains why microbiome research demands a creative and interdisciplinary thinking—the capacity to combine microbiology with human, animal and plant physiology, ecological theory with immunology, and evolutionary perspectives with metabolic science.This book provides an accessible and authoritative guide to the fundamental principles of microbiome science, an exciting and fast-emerging new discipline that is reshaping many aspects of the life sciences. These microbial partners can also drive ecologically important traits, from thermal tolerance to diet in a typical immune system, and have contributed to animal and plant diversification over long evolutionary timescales. Also this book explains why microbiome research presents a more complete picture of the biology of humans and other animals, and how it can deliver novel therapies for human health and new strategies.

The Human Microbiota

David N. Fredricks
The Human Microbiota Book PDF

Author : David N. Fredricks
Publisher : John Wiley & Sons
Page : 348 pages
File Size : 49,5 Mb
Release : 2013-02-22
Category : Science
ISBN : 9781118409800

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The Human Microbiota by David N. Fredricks Pdf

The Human Microbiota offers a comprehensive review of all human-associated microbial niches in a single volume, focusing on what modern tools in molecular microbiology are revealing about human microbiota, and how specific microbial communities can be associated with either beneficial effects or diseases. An excellent resource for microbiologists, physicians, infectious disease specialists, and others in the field, the book describes the latest research findings and evaluates the most innovative research approaches and technologies. Perspectives from pioneers in human microbial ecology are provided throughout.

The Human Microbiome, Diet, and Health

Food Forum,Food and Nutrition Board,Institute of Medicine
The Human Microbiome Diet and Health Book PDF

Author : Food Forum,Food and Nutrition Board,Institute of Medicine
Publisher : National Academies Press
Page : 161 pages
File Size : 40,8 Mb
Release : 2013-02-27
Category : Medical
ISBN : 9780309265867

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The Human Microbiome, Diet, and Health by Food Forum,Food and Nutrition Board,Institute of Medicine Pdf

The Food Forum convened a public workshop on February 22-23, 2012, to explore current and emerging knowledge of the human microbiome, its role in human health, its interaction with the diet, and the translation of new research findings into tools and products that improve the nutritional quality of the food supply. The Human Microbiome, Diet, and Health: Workshop Summary summarizes the presentations and discussions that took place during the workshop. Over the two day workshop, several themes covered included: The microbiome is integral to human physiology, health, and disease. The microbiome is arguably the most intimate connection that humans have with their external environment, mostly through diet. Given the emerging nature of research on the microbiome, some important methodology issues might still have to be resolved with respect to undersampling and a lack of causal and mechanistic studies. Dietary interventions intended to have an impact on host biology via their impact on the microbiome are being developed, and the market for these products is seeing tremendous success. However, the current regulatory framework poses challenges to industry interest and investment.

The Human Microbiota and Microbiome

Julian R Marchesi
The Human Microbiota and Microbiome Book PDF

Author : Julian R Marchesi
Publisher : CABI
Page : 208 pages
File Size : 50,5 Mb
Release : 2014-05-14
Category : Medical
ISBN : 9781780640495

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The Human Microbiota and Microbiome by Julian R Marchesi Pdf

Thousands of different microbial species colonize the human body, and are essential for our survival. This book presents a review of the current understanding of human microbiomes, the functions that they bring to the host, how we can model them, their role in health and disease and the methods used to explore them. Current research into areas such as the long-term effect of antibiotics makes this a subject of considerable interest. This title is essential reading for researchers and students of microbiology.

The Human Microbiome in Early Life

Omry Koren,Samuli Rautava
The Human Microbiome in Early Life Book PDF

Author : Omry Koren,Samuli Rautava
Publisher : Academic Press
Page : 327 pages
File Size : 40,6 Mb
Release : 2020-09-18
Category : Science
ISBN : 9780128180983

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The Human Microbiome in Early Life by Omry Koren,Samuli Rautava Pdf

The Human Microbiome in Early Life: Implications to Health and Disease presents recent research advances that have highlighted the significance of early life, possibly beginning before birth, in the establishment of both the microbiome and its role in health and disease. The book reviews current knowledge on the origins of the human microbiota in early life, presents exposures which may disturb normal microbial colonization, and covers their implications to the risk of disease. Finally, emerging means to modify the early human microbiome to improve health are discussed. Examines the timeline of the human microbiome, from before conception to infancy, with an emphasis on clinical implications Evaluates the effort to understand not only the composition but also the origin of the microbiome Proves the emerging means to modify the human microbiome and particularly ‘the first 1000 days of life’ improve human health and prevent disease Generates resources to facilitate characterization of the human microbiota to further our understanding of how the microbiome impacts human health and disease

The Chemistry of Microbiomes

National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Chemical Sciences and Technology,Chemical Sciences Roundtable
The Chemistry of Microbiomes Book PDF

Author : National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Chemical Sciences and Technology,Chemical Sciences Roundtable
Publisher : National Academies Press
Page : 133 pages
File Size : 47,8 Mb
Release : 2017-07-19
Category : Science
ISBN : 9780309458399

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The Chemistry of Microbiomes by National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Chemical Sciences and Technology,Chemical Sciences Roundtable Pdf

The 21st century has witnessed a complete revolution in the understanding and description of bacteria in eco- systems and microbial assemblages, and how they are regulated by complex interactions among microbes, hosts, and environments. The human organism is no longer considered a monolithic assembly of tissues, but is instead a true ecosystem composed of human cells, bacteria, fungi, algae, and viruses. As such, humans are not unlike other complex ecosystems containing microbial assemblages observed in the marine and earth environments. They all share a basic functional principle: Chemical communication is the universal language that allows such groups to properly function together. These chemical networks regulate interactions like metabolic exchange, antibiosis and symbiosis, and communication. The National Academies of Sciences, Engineering, and Medicine's Chemical Sciences Roundtable organized a series of four seminars in the autumn of 2016 to explore the current advances, opportunities, and challenges toward unveiling this "chemical dark matter" and its role in the regulation and function of different ecosystems. The first three focused on specific ecosystemsâ€"earth, marine, and humanâ€"and the last on all microbiome systems. This publication summarizes the presentations and discussions from the seminars.

Gut Microbiota in Neurologic and Visceral Diseases

Tahira Farooqui,Akhlaq A. Farooqui
Gut Microbiota in Neurologic and Visceral Diseases Book PDF

Author : Tahira Farooqui,Akhlaq A. Farooqui
Publisher : Academic Press
Page : 388 pages
File Size : 49,5 Mb
Release : 2021-03-11
Category : Medical
ISBN : 9780128210406

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Gut Microbiota in Neurologic and Visceral Diseases by Tahira Farooqui,Akhlaq A. Farooqui Pdf

Gut Microbiota in Neurologic and Visceral Diseases presents readers with comprehensive information on the involvement of microbiota in the pathogenesis of neurological disorders. Chapters cover the effect of microbiota on the development of visceral (obesity, type 2 diabetes, heart disease) and neurological disorders (Alzheimer’s disease, Parkinson’s, depression, anxiety, and autism). Sections focus on the molecular mechanisms and signal transduction processes associated with the links among microbiota-related visceral and neurological disorders. It is hoped that this discussion will not only integrate and consolidate knowledge in this field but will also jumpstart more studies on the involvement of microbiota in the pathogenesis of neurological disorders. Reviews the relationship between gut microbiome, diseases and disorders Discusses the relationship between diet, microbiota and inflammation Includes neurodegenerative, neuropsychiatric and cardiovascular disorders Covers diabetes, obesity and metabolic disorders Identifies molecular mechanisms and signal transduction processes Encompasses dietary fiber, fat, prebiotics and probiotics

Diet, Microbiome and Health

Alexandru Mihai Grumezescu,Alina-Maria Holban
Diet Microbiome and Health Book PDF

Author : Alexandru Mihai Grumezescu,Alina-Maria Holban
Publisher : Academic Press
Page : 526 pages
File Size : 46,9 Mb
Release : 2018-01-02
Category : Technology & Engineering
ISBN : 9780128114926

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Diet, Microbiome and Health by Alexandru Mihai Grumezescu,Alina-Maria Holban Pdf

Diet, Microbiome and Health, Volume 11, in the Handbook of Food Bioengineering series, presents the most up-to-date research to help scientists, researchers and students in the field of food engineering understand the different microbial species we have in our guts, why they are important to human development, immunity and health, and how to use that understanding to further promote research to create healthy food products. In addition, the book provides studies that clearly demonstrate how dietary preferences and social behavior significantly impact the diversity of microbial species in the gut and their numeric values, which may balance health and disease. Highlights research discoveries on how gut microbiota influence and are impacted by health and disease Includes information on and examples of healthy foods Discusses gut microbiota in autism, GI disease, neuropsychiatric disorders, obesity and metabolic disease Explores the barrier function of the gut Examines how food preferences impact gut microbiota

Microbiota of the Human Body

Andreas Schwiertz
Microbiota of the Human Body Book PDF

Author : Andreas Schwiertz
Publisher : Springer
Page : 157 pages
File Size : 43,9 Mb
Release : 2016-05-09
Category : Science
ISBN : 9783319312484

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Microbiota of the Human Body by Andreas Schwiertz Pdf

Microbes can now be found in nearly every niche the human body offers. However, the complexity of the microbiota of a given site depends on the particular environmental condition thereof. Only microbes which are able to grow under these conditions, will prevail. Recent publications imply that the microorganisms do not only have multiple, critical consequences for host physiological processes such as postnatal development, immunomodulation and energy supply, but also effects on neurodevelopment, behavior and cognition. Within this book we will focus on the techniques behind these developments, epigenomics and on the various parts of the human body which are inhabited by microorganism such as the mouth, the gut, the skin and the vagina. In addition, chapters are dedicated to the possible manipulations of the microbiota by probiotics, prebiotics and faecal transplantation.

Environmental Chemicals, the Human Microbiome, and Health Risk

National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Life Sciences,Board on Environmental Studies and Toxicology,Committee on Advancing Understanding of the Implications of Environmental-Chemical Interactions with the Human Microbiome
Environmental Chemicals the Human Microbiome and Health Risk Book PDF

Author : National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Life Sciences,Board on Environmental Studies and Toxicology,Committee on Advancing Understanding of the Implications of Environmental-Chemical Interactions with the Human Microbiome
Publisher : National Academies Press
Page : 123 pages
File Size : 53,8 Mb
Release : 2018-03-01
Category : Science
ISBN : 9780309468695

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Environmental Chemicals, the Human Microbiome, and Health Risk by National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Life Sciences,Board on Environmental Studies and Toxicology,Committee on Advancing Understanding of the Implications of Environmental-Chemical Interactions with the Human Microbiome Pdf

A great number of diverse microorganisms inhabit the human body and are collectively referred to as the human microbiome. Until recently, the role of the human microbiome in maintaining human health was not fully appreciated. Today, however, research is beginning to elucidate associations between perturbations in the human microbiome and human disease and the factors that might be responsible for the perturbations. Studies have indicated that the human microbiome could be affected by environmental chemicals or could modulate exposure to environmental chemicals. Environmental Chemicals, the Human Microbiome, and Health Risk presents a research strategy to improve our understanding of the interactions between environmental chemicals and the human microbiome and the implications of those interactions for human health risk. This report identifies barriers to such research and opportunities for collaboration, highlights key aspects of the human microbiome and its relation to health, describes potential interactions between environmental chemicals and the human microbiome, reviews the risk-assessment framework and reasons for incorporating chemicalâ€"microbiome interactions.

Microbial Inhabitants of Humans

Michael Wilson
Microbial Inhabitants of Humans Book PDF

Author : Michael Wilson
Publisher : Cambridge University Press
Page : 480 pages
File Size : 41,8 Mb
Release : 2005
Category : Medical
ISBN : 0521841585

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Microbial Inhabitants of Humans by Michael Wilson Pdf

This advanced textbook provides a unique overview of the microbial communities (normal indigenous microbiota) inhabiting those regions of the human body that are exposed to the external environment, including the skin, eyes, oral cavity and the respiratory, urinary, reproductive and gastrointestinal tracts. In order to understand why particular organisms are able to colonise an anatomical region and why the resulting microbial community has a particular composition, an ecological approach is essential. Consequently, the key anatomical and physiological characteristics of each body site are described throughout the book. The crucial roles of the indigenous microbiota in protecting against exogenous pathogens, regulating the development of our immune system and mucosae, and providing nutrients are also discussed. The involvement of these organisms in infections of healthy and debilitated individuals are discussed throughout and methods of manipulating the composition of the indigenous microbiota for the benefit of human health are also described.