The Immune System And Mental Health

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The Immune System and Mental Health

Hymie Anisman,Shawn Hayley,Alexander Kusnecov
The Immune System and Mental Health Book PDF

Author : Hymie Anisman,Shawn Hayley,Alexander Kusnecov
Publisher : Academic Press
Page : 700 pages
File Size : 41,9 Mb
Release : 2018-07-19
Category : Medical
ISBN : 9780128113523

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The Immune System and Mental Health by Hymie Anisman,Shawn Hayley,Alexander Kusnecov Pdf

The Immune System and Mental Health fully investigates how immune-related cellular, molecular and anatomical changes impact mental functioning. The book combines human and animal studies to reveal immunological changes related to mental-health problems. In addition, users will find comprehensive information on new research related to the microbial composition of the gut, aka, the microbiome, and how it influences brain function and mental health. Common comorbidities with mental illness and their inherent immunological or inflammatory components are also covered. Written by leaders in the field, the book synthesizes basic and clinical research to provide a thorough understanding on the role of immunity in neuropsychiatry. Sociology, psychology, psychiatry, neuroscience and genetics have provided considerable explanations and solutions to some of the most intractable mental-health problems. But researchers are increasingly relying on investigations of the immune system to identify factors that can undermine and impair mental health. This book covers devastating mental-health conditions, such as depression, anxiety, schizophrenia, and autism-like spectrum disorders. In addition, degenerative disorders of the brain, such as Parkinson’s and Alzheimer’s-like dementia are explored. Considers both basic human and animal studies that address immunological changes relating to mental health problems across the lifespan Incorporates techniques, concepts and ideas from a variety of social, behavioral and life sciences Explores the relatively new area of the microbiome and how the microbial composition of the gut influences brain function and mental health

Stress Challenges and Immunity in Space

Alexander Choukèr
Stress Challenges and Immunity in Space Book PDF

Author : Alexander Choukèr
Publisher : Springer Nature
Page : 756 pages
File Size : 46,5 Mb
Release : 2019-11-27
Category : Medical
ISBN : 9783030169961

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Stress Challenges and Immunity in Space by Alexander Choukèr Pdf

This book explains how stress – either psychological or physical – can activate and/or paralyse human innate or adaptive immunity. Adequate immunity is crucial for maintaining health, both on Earth and in space. During space flight, human physiology is specifically challenged by complex environmental stressors, which are most pronounced during lunar or interplanetary missions. Adopting an interdisciplinary approach, the book identifies the impact of these stressors – the space exposome – on immunity as a result of (dys-)functions of specific cells, organs and organ networks. These conditions (e.g. gravitation changes, radiation, isolation/confinement) affect immunity, but at the same time provide insights that may help to prevent, diagnose and address immune-related health alterations. Written by experts from academia, space agencies and industry, the book is a valuable resource for professionals, researchers and students in the field of medicine, biology and technology. The chapters “The Impact of Everyday Stressors on the Immune System and Health”, “Stress and Radiation Responsiveness” and “Assessment of Radiosensitivity and Biomonitoring of Exposure to Space adiation” are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Immunopsychiatry

Antonio L. Teixeira,Moises E. Bauer
Immunopsychiatry Book PDF

Author : Antonio L. Teixeira,Moises E. Bauer
Publisher : Oxford University Press, USA
Page : 323 pages
File Size : 55,8 Mb
Release : 2019-01-18
Category : Science
ISBN : 9780190884468

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Immunopsychiatry by Antonio L. Teixeira,Moises E. Bauer Pdf

In recent years, a dedicated effort has been made to understand the immune dysfunction that is associated with major psychiatric disorders. The expanding knowledge of the immune system as a major homeostatic system has been very helpful in indicating new potential biomarkers and therapeutic targets to reduce the burden of psychiatric disorders. Indeed, immune cells, their secreted molecules, and cell signalling events are highly promising. Yet, the literature on immunology of psychiatric disorders is still dispersed, and only a few attempts have been made to consolidate the current knowledge in this expanding area. This book assembles and presents the available data on the immune/inflammatory dysfunction in psychiatric disorders, indicating the potential of immune mechanisms as either biomarkers or therapeutic targets, as well as discussing the challenges ahead of incorporating this knowledge into clinical practice. An international team of senior experts in the field review all psychiatric disorders in order to provide an integrated, in-depth understanding of the role of immune changes in psychiatric diseases for mental health clinicians as well as for researchers in immunology, psychiatry, neurology, and pharmacology.

Immuno-Psychiatry

Michael Berk,Marion Leboyer,Iris E. Sommer
Immuno Psychiatry Book PDF

Author : Michael Berk,Marion Leboyer,Iris E. Sommer
Publisher : Springer Nature
Page : 438 pages
File Size : 53,5 Mb
Release : 2021-08-14
Category : Medical
ISBN : 9783030712297

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Immuno-Psychiatry by Michael Berk,Marion Leboyer,Iris E. Sommer Pdf

This book presents a thorough and critical review of current knowledge on the role of immunology in major psychiatric disorders and its potential applications. The opening chapters offer general information on the immune influence of the brain to provide readers with a better understanding of the end of immune privilege. The book then examines possible underlying mechanisms leading to psychiatric disorders, from early infections to pro-inflammatory markers, stress, and immune genetic background, linking etiology and psychiatry. The third section describes each disorder (ie autism, schizophrenia, bipolar disorder, depression...) with an overview of underlying immune dysfunctions. Lastly, the authors discuss the innovative immune-therapies that may result from the discovery of immune system biomarkers and their associated mechanisms. A better understanding of the role of the immune system in psychiatric disorders makes it possible to identify stratification biomarkers, to explain underlying mechanisms, and to develop innovative, efficient, targeted treatment strategies and management. As such, the book is of value to clinicians, mental health professionals, mental health researchers, immunologists, industry practitioners, and various stakeholders in the mental health field.

Comorbidity of Mental and Physical Disorders

N. Sartorius,R.I.G. Holt,M. Maj
Comorbidity of Mental and Physical Disorders Book PDF

Author : N. Sartorius,R.I.G. Holt,M. Maj
Publisher : Karger Medical and Scientific Publishers
Page : 200 pages
File Size : 55,8 Mb
Release : 2014-12-01
Category : Psychology
ISBN : 9783318026047

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Comorbidity of Mental and Physical Disorders by N. Sartorius,R.I.G. Holt,M. Maj Pdf

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Textbook of Immunopsychiatry

Golam Khandaker,Neil Harrison,Edward Bullmore,Robert Dantzer
Textbook of Immunopsychiatry Book PDF

Author : Golam Khandaker,Neil Harrison,Edward Bullmore,Robert Dantzer
Publisher : Cambridge University Press
Page : 357 pages
File Size : 40,5 Mb
Release : 2021-09-23
Category : Medical
ISBN : 9781108424042

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Textbook of Immunopsychiatry by Golam Khandaker,Neil Harrison,Edward Bullmore,Robert Dantzer Pdf

An essential book summarizing cutting-edge evidence on the role of the immune system and immunotherapies in psychiatric disorders.

Immunopsychiatry

Antonio L. Teixeira,Moises E. Bauer
Immunopsychiatry Book PDF

Author : Antonio L. Teixeira,Moises E. Bauer
Publisher : Oxford University Press
Page : 304 pages
File Size : 49,9 Mb
Release : 2019-01-03
Category : Science
ISBN : 9780190884475

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Immunopsychiatry by Antonio L. Teixeira,Moises E. Bauer Pdf

In recent years, a dedicated effort has been made to understand the immune dysfunction that is associated with major psychiatric disorders. The expanding knowledge of the immune system as a major homeostatic system has been very helpful in indicating new potential biomarkers and therapeutic targets to reduce the burden of psychiatric disorders. Indeed, immune cells, their secreted molecules, and cell signalling events are highly promising. Yet, the literature on immunology of psychiatric disorders is still dispersed, and only a few attempts have been made to consolidate the current knowledge in this expanding area. This book assembles and presents the available data on the immune/inflammatory dysfunction in psychiatric disorders, indicating the potential of immune mechanisms as either biomarkers or therapeutic targets, as well as discussing the challenges ahead of incorporating this knowledge into clinical practice. An international team of senior experts in the field review all psychiatric disorders in order to provide an integrated, in-depth understanding of the role of immune changes in psychiatric diseases for mental health clinicians as well as for researchers in immunology, psychiatry, neurology, and pharmacology.

The Neurobiological Basis of Suicide

Yogesh Dwivedi
The Neurobiological Basis of Suicide Book PDF

Author : Yogesh Dwivedi
Publisher : CRC Press
Page : 485 pages
File Size : 43,9 Mb
Release : 2012-06-25
Category : Medical
ISBN : 9781439838815

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The Neurobiological Basis of Suicide by Yogesh Dwivedi Pdf

With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.

Microbes and the Mind

C.S.M. Cowan,B.E. Leonard
Microbes and the Mind Book PDF

Author : C.S.M. Cowan,B.E. Leonard
Publisher : Karger Medical and Scientific Publishers
Page : 158 pages
File Size : 50,6 Mb
Release : 2021-05-06
Category : Medical
ISBN : 9783318068566

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Microbes and the Mind by C.S.M. Cowan,B.E. Leonard Pdf

Interest in the mind-body connection has grown in recent years, with accumulating evidence showing that the gut microbiome can alter behavioral, neural, and psychological outcomes. This publication brings together a group of international experts who are investigating the microbiome and its potential to contribute to the causes and treatment of mental illness. The contributions are not aimed solely at specialists in clinical and experimental neuroscience. They cover a range of key topics, including the role of the microbiome in mental health and specific psychiatric disorders that occur across the lifespan, interactions with the immune system, diet, and pharmacological interventions. Furthermore, the microbial metabolite production and the potential for psychobiotic interventions that target the microbiome to improve mental health outcomes are discussed. This book is unique in its focus on the mechanisms and consequences of the activities of gut microorganisms in mental health and illness, providing expert insight into the current state of the art and important future directions for this emerging area of research. Additionally, it provides an excellent knowledge base for newcomers and a refresher for researchers and clinicians working in the fields of neuroscience, psychology, or psychiatry.

Inflammation and Immunity in Depression

Bernhard Baune
Inflammation and Immunity in Depression Book PDF

Author : Bernhard Baune
Publisher : Academic Press
Page : 636 pages
File Size : 50,9 Mb
Release : 2018-05-23
Category : Medical
ISBN : 9780128110744

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Inflammation and Immunity in Depression by Bernhard Baune Pdf

Inflammation and Immunity in Depression: Basic Science and Clinical Applications is the first book to move beyond the established theory of cytokine-induced depression and explore the broader role the immune system plays in this devastating mood disorder. The book fully explores the most recent lines of research into this rapidly advancing field, including alterations of T-cells, the neurobiological implications of neuroinflammation and immune alterations for brain development and function, and the genetic components of neuroinflammation in depression, including the relationships between stress and inflammation that are revealing gene-environment interactions in the disorder. Combining contributions from researchers worldwide, this book provides the most comprehensive discussion available today on the involvement of the innate immune and adaptive immune systems in depressive disorder. Chapters span neuroscience, psychology, clinical applications and future directions, making this book an invaluable resource for advanced students, researchers and practitioners who need to understand the complex and varied role of inflammation and immune responses in depression. Synthesizes current knowledge of inflammation and immunity in depression, ranging from basic neuroscience research, to clinical applications in psychiatry Expands on the long-established theory of cytokine-induced depression to discuss broader involvement of the immune system Explores translational potential of targeting immune dysfunction for clinical interventions

The Inflamed Mind

Edward Bullmore
The Inflamed Mind Book PDF

Author : Edward Bullmore
Publisher : Picador
Page : 256 pages
File Size : 50,5 Mb
Release : 2018-12-31
Category : Psychology
ISBN : 9781250318152

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The Inflamed Mind by Edward Bullmore Pdf

As seen on "CBS This Morning" Worldwide, depression will be the single biggest cause of disability in the next twenty years. But treatment for it has not changed much in the last three decades. In the world of psychiatry, time has apparently stood still...until now with Edward Bullmore's The Inflamed Mind: A Radical New Approach to Depression. A Sunday Times (London) Top Ten Bestseller In this game-changing book, University of Cambridge profressor of psychiatry Edward Bullmore reveals the breakthrough new science on the link between depression and inflammation of the body and brain. He explains how and why we now know that mental disorders can have their root cause in the immune system, and outlines a future revolution in which treatments could be specifically targeted to break the vicious cycles of stress, inflammation, and depression. The Inflamed Mind goes far beyond the clinic and the lab, representing a whole new way of looking at how mind, brain, and body all work together in a sometimes misguided effort to help us survive in a hostile world. It offers insights into how we could start getting to grips with depression and other mental disorders much more effectively in the future.

Stress, Immune Function, and Health

Bruce S. Rabin
Stress Immune Function and Health Book PDF

Author : Bruce S. Rabin
Publisher : Wiley-Liss
Page : 368 pages
File Size : 45,9 Mb
Release : 1999-03-05
Category : Medical
ISBN : UOM:39015042760028

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Stress, Immune Function, and Health by Bruce S. Rabin Pdf

Written by a renowned figure in the field of immunology and compiling a wealth of scientific information, Stress, Immune Function, and Health: The Connection looks at the long-term effects of stress on human health from a psychoneuroimmunological approach. The recent changes in dietary modifications, clinical applications, and evolution in the field of immunology have created the need for a book which addresses the growing awareness of health benefits that can be achieved by buffering the effects of stress on the immune system. Emphasizing the importance of the interaction among the mind, the body, and physical health, this reference includes important developmental procedures that can be used to resist stress on the immune system. By examining components of the immune system, along with the effects of psychological stress and the capacity for hormonal response, author Bruce Rabin demonstrates, in a concise, accessible manner, the ability of an individual's immune system to alter susceptibility to immune-mediated diseases. In addition, the book examines several key issues in this rapidly expanding field, including: * Information and examples that illustrate how distinct areas of the brain that perceive the presence of a stressor are able to communicate with the cells of the immune system * The correlation between stress-related changes in health practices and stressor-induced risks of disease development * The effect on the immune system due to stress from an increased concentration of neuropeptides and hormones * Behaviors and beliefs that can reduce the harmful effects of stress on the immune system by interfering with the stress-responsive areas of the brain * The issue of stress during pregnancy and the early period of development on behaviors and immune functions in children An authoritative guide for all researchers and students in the fields of immunology, neuroscience, and psychology, Stress, Immune Function, and Health: The Connection is also an essential reference for physicians and nurses concerned with stress and immune-related diseases.

The Oxford Handbook of Stress and Mental Health

Kate L. Harkness,Elizabeth P. Hayden
The Oxford Handbook of Stress and Mental Health Book PDF

Author : Kate L. Harkness,Elizabeth P. Hayden
Publisher : Oxford University Press, USA
Page : 769 pages
File Size : 47,5 Mb
Release : 2020
Category : Psychology
ISBN : 9780190681777

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The Oxford Handbook of Stress and Mental Health by Kate L. Harkness,Elizabeth P. Hayden Pdf

This handbook is currently in development, with individual articles publishing online in advance of print publication. At this time, we cannot add information about unpublished articles in this handbook, however the table of contents will continue to grow as additional articles pass through the review process and are added to the site. Please note that the online publication date for this handbook is the date that the first article in the title was published online.

Functional Somatic Symptoms in Children and Adolescents

Kasia Kozlowska,Stephen Scher,Helene Helgeland
Functional Somatic Symptoms in Children and Adolescents Book PDF

Author : Kasia Kozlowska,Stephen Scher,Helene Helgeland
Publisher : Springer Nature
Page : 397 pages
File Size : 41,6 Mb
Release : 2020-09-30
Category : Psychology
ISBN : 9783030461843

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Functional Somatic Symptoms in Children and Adolescents by Kasia Kozlowska,Stephen Scher,Helene Helgeland Pdf

This open access book sets out the stress-system model for functional somatic symptoms in children and adolescents. The book begins by exploring the initial encounter between the paediatrician, child, and family, moves through the assessment process, including the formulation and the treatment contract, and then describes the various forms of treatment that are designed to settle the child’s dysregulated stress system. This approach both provides a new understanding of how such symptoms emerge – typically, through a history of recurrent or chronic stress, either physical or psychological – and points the way to effective assessment, management, and treatment that put the child (and family) back on the road to health and well-being.

Homelessness, Health, and Human Needs

Institute of Medicine,Committee on Health Care for Homeless People
Homelessness Health and Human Needs Book PDF

Author : Institute of Medicine,Committee on Health Care for Homeless People
Publisher : National Academies Press
Page : 257 pages
File Size : 52,9 Mb
Release : 1988-02-01
Category : Medical
ISBN : 9780309038324

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Homelessness, Health, and Human Needs by Institute of Medicine,Committee on Health Care for Homeless People Pdf

There have always been homeless people in the United States, but their plight has only recently stirred widespread public reaction and concern. Part of this new recognition stems from the problem's prevalence: the number of homeless individuals, while hard to pin down exactly, is rising. In light of this, Congress asked the Institute of Medicine to find out whether existing health care programs were ignoring the homeless or delivering care to them inefficiently. This book is the report prepared by a committee of experts who examined these problems through visits to city slums and impoverished rural areas, and through an analysis of papers written by leading scholars in the field.