The Implicit Genome

Author : Lynn Helena Caporale
Publisher : Oxford University Press
Page : 398 pages
File Size : 41,8 Mb
Release : 2006-02-02
Category : Science
ISBN : 9780195172706

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The Implicit Genome by Lynn Helena Caporale Pdf

In its beautiful simplicity, the double-helicaln stucture of DNA had entranced us into believing that we can fully understand the information content of a DNA sequence, simply by treating it as text that is read in a linear fashion. While we have learned much based on this assumption, there is much we have missed. Far from a passive tape running through a reader, genomes contain information that appears in new forms which create regions with distinct behavior. The chapters in this volume touch on one or more of three interconnected themes; information can be implied, rather than explicit, in a genome; information can lead to focused and/or regulated changes in nucleotide sequences; information that affects the probability of distinct classes of mutation has implications for evolutionary theory.

Author : Lynn Helena Caporale
Publisher : Oxford University Press
Page : 399 pages
File Size : 43,6 Mb
Release : 2006-02-02
Category : Science
ISBN : 0195172701

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The Implicit Genome by Lynn Helena Caporale Pdf

In its beautiful simplicity, the double-helicaln stucture of DNA had entranced us into believing that we can fully understand the information content of a DNA sequence, simply by treating it as text that is read in a linear fashion. While we have learned much based on this assumption, there is much we have missed. Far from a passive tape running through a reader, genomes contain information that appears in new forms which create regions with distinct behavior. The chapters in this volume touch on one or more of three interconnected themes; information can be implied, rather than explicit, in a genome; information can lead to focused and/or regulated changes in nucleotide sequences; information that affects the probability of distinct classes of mutation has implications for evolutionary theory.

Author : Pradeep Chhaya
Publisher : Springer Nature
Page : 562 pages
File Size : 49,7 Mb
Release : 2024-06-26
Category : Electronic
ISBN : 9789819943180

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The Topological Model of Genome and Evolution by Pradeep Chhaya Pdf

Author : Richard Dawkins
Publisher : Oxford University Press, USA
Page : 372 pages
File Size : 45,8 Mb
Release : 1989
Category : Medical
ISBN : 0192860925

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The Selfish Gene by Richard Dawkins Pdf

Science need not be dull and bogged down by jargon, as Richard Dawkins proves in this entertaining look at evolution. The themes he takes up are the concepts of altruistic and selfish behaviour; the genetical definition of selfish interest; the evolution of aggressive behaviour; kinshiptheory; sex ratio theory; reciprocal altruism; deceit; and the natural selection of sex differences. 'Should be read, can be read by almost anyone. It describes with great skill a new face of the theory of evolution.' W.D. Hamilton, Science

Author : Evelyn Fox KELLER
Publisher : Harvard University Press
Page : 194 pages
File Size : 44,6 Mb
Release : 2009-06-30
Category : Science
ISBN : 9780674039438

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The Century of the Gene by Evelyn Fox KELLER Pdf

In a book that promises to change the way we think and talk about genes and genetic determinism, Evelyn Fox Keller, one of our most gifted historians and philosophers of science, provides a powerful, profound analysis of the achievements of genetics and molecular biology in the twentieth century, the century of the gene. Not just a chronicle of biology’s progress from gene to genome in one hundred years, The Century of the Gene also calls our attention to the surprising ways these advances challenge the familiar picture of the gene most of us still entertain. Keller shows us that the very successes that have stirred our imagination have also radically undermined the primacy of the gene—word and object—as the core explanatory concept of heredity and development. She argues that we need a new vocabulary that includes concepts such as robustness, fidelity, and evolvability. But more than a new vocabulary, a new awareness is absolutely crucial: that understanding the components of a system (be they individual genes, proteins, or even molecules) may tell us little about the interactions among these components. With the Human Genome Project nearing its first and most publicized goal, biologists are coming to realize that they have reached not the end of biology but the beginning of a new era. Indeed, Keller predicts that in the new century we will witness another Cambrian era, this time in new forms of biological thought rather than in new forms of biological life.

Author : Lynn Helena Caporale
Publisher : Darwin in the Genome
Page : 259 pages
File Size : 48,7 Mb
Release : 2003
Category : Business & Economics
ISBN : 9780071378222

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Darwin in the Genome by Lynn Helena Caporale Pdf

Publisher Description

Author : National Research Council,Division on Engineering and Physical Sciences,Space Studies Board,Commission on Physical Sciences, Mathematics, and Applications,Steering Group for the Workshop on Size Limits of Very Small Microorganisms
Publisher : National Academies Press
Page : 171 pages
File Size : 40,7 Mb
Release : 1999-09-13
Category : Science
ISBN : 9780309172745

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Size Limits of Very Small Microorganisms by National Research Council,Division on Engineering and Physical Sciences,Space Studies Board,Commission on Physical Sciences, Mathematics, and Applications,Steering Group for the Workshop on Size Limits of Very Small Microorganisms Pdf

How small can a free-living organism be? On the surface, this question is straightforward-in principle, the smallest cells can be identified and measured. But understanding what factors determine this lower limit, and addressing the host of other questions that follow on from this knowledge, require a fundamental understanding of the chemistry and ecology of cellular life. The recent report of evidence for life in a martian meteorite and the prospect of searching for biological signatures in intelligently chosen samples from Mars and elsewhere bring a new immediacy to such questions. How do we recognize the morphological or chemical remnants of life in rocks deposited 4 billion years ago on another planet? Are the empirical limits on cell size identified by observation on Earth applicable to life wherever it may occur, or is minimum size a function of the particular chemistry of an individual planetary surface? These questions formed the focus of a workshop on the size limits of very small organisms, organized by the Steering .Group for the Workshop on Size Limits of Very Small Microorganisms and held on October 22 and 23, 1998. Eighteen invited panelists, representing fields ranging from cell biology and molecular genetics to paleontology and mineralogy, joined with an almost equal number of other participants in a wide-ranging exploration of minimum cell size and the challenge of interpreting micro- and nano-scale features of sedimentary rocks found on Earth or elsewhere in the solar system. This document contains the proceedings of that workshop. It includes position papers presented by the individual panelists, arranged by panel, along with a summary, for each of the four sessions, of extensive roundtable discussions that involved the panelists as well as other workshop participants.

Author : National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on Mapping and Sequencing the Human Genome
Publisher : National Academies Press
Page : 128 pages
File Size : 50,9 Mb
Release : 1988-01-01
Category : Science
ISBN : 9780309038409

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Mapping and Sequencing the Human Genome by National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on Mapping and Sequencing the Human Genome Pdf

There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.

Author : National Academy of Sciences
Publisher : Sackler Colloquium
Page : 388 pages
File Size : 42,7 Mb
Release : 2007
Category : Science
ISBN : UOM:39015073872999

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In the Light of Evolution by National Academy of Sciences Pdf

The Arthur M. Sackler Colloquia of the National Academy of Sciences address scientific topics of broad and current interest, cutting across the boundaries of traditional disciplines. Each year, four or five such colloquia are scheduled, typically two days in length and international in scope. Colloquia are organized by a member of the Academy, often with the assistance of an organizing committee, and feature presentations by leading scientists in the field and discussions with a hundred or more researchers with an interest in the topic. Colloquia presentations are recorded and posted on the National Academy of Sciences Sackler colloquia website and published on CD-ROM. These Colloquia are made possible by a generous gift from Mrs. Jill Sackler, in memory of her husband, Arthur M. Sackler.

Author : Anonim
Publisher : Unknown
Page : 588 pages
File Size : 48,8 Mb
Release : 2006
Category : Ecology
ISBN : UOM:39015072607156

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Israel Journal of Ecology & Evolution by Anonim Pdf

Author : James D. Watson,Tania A. Baker,Stephen P. Bell
Publisher : Benjamin-Cummings Publishing Company
Page : 872 pages
File Size : 51,7 Mb
Release : 2014
Category : Medical
ISBN : 0321762436

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Molecular Biology of the Gene by James D. Watson,Tania A. Baker,Stephen P. Bell Pdf

Now completely up-to-date with the latest research advances, the Seventh Edition retains the distinctive character of earlier editions. Twenty-two concise chapters, co-authored by six highly distinguished biologists, provide current, authoritative coverage of an exciting, fast-changing discipline.

Author : Lynn Margulis,Dorion Sagan
Publisher : Basic Books
Page : 262 pages
File Size : 51,6 Mb
Release : 2008-08-01
Category : Science
ISBN : 9780786722600

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Acquiring Genomes by Lynn Margulis,Dorion Sagan Pdf

In this groundbreaking book, Lynn Margulis and Dorion Sagan present an answer to one of the enduring mysteries of evolution -- the source of inherited variation that gives rise to new species. Random genetic mutation, long believed to be the main source of variation, is only a marginal factor. As the authors demonstrate in this book, the more important source of speciation, by far, is the acquisition of new genomes by symbiotic merger. The result of thirty years of delving into a vast, mostly arcane literature, this is the first book to go beyond -- and reveal the severe limitations of -- the "Modern Synthesis" that has dominated evolutionary biology for almost three generations. Lynn Margulis, whom E. O. Wilson called "one of the most successful synthetic thinkers in modern biology," and her co-author Dorion Sagan have written a comprehensive and scientifically supported presentation of a theory that directly challenges the assumptions we hold about the variety of the living world.

Author : David Botstein
Publisher : Unknown
Page : 0 pages
File Size : 43,9 Mb
Release : 2015
Category : SCIENCE
ISBN : 1621820920

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Decoding the Language of Genetics by David Botstein Pdf

"This is a book about the conceptual language of genetics. There is a need for special words and terms to deal with some of the essential abstractions in genetics; these are the focus of this book. It is intended to help readers with diverse interests and experience to think about genetic analysis in a more sophisticated and creative way."--Publisher information.

Author : Sarah S. Richardson
Publisher : University of Chicago Press
Page : 320 pages
File Size : 43,9 Mb
Release : 2013-12-13
Category : Science
ISBN : 9780226084718

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Sex Itself by Sarah S. Richardson Pdf

Human genomes are 99.9 percent identical—with one prominent exception. Instead of a matching pair of X chromosomes, men carry a single X, coupled with a tiny chromosome called the Y. Tracking the emergence of a new and distinctive way of thinking about sex represented by the unalterable, simple, and visually compelling binary of the X and Y chromosomes, Sex Itself examines the interaction between cultural gender norms and genetic theories of sex from the beginning of the twentieth century to the present, postgenomic age. Using methods from history, philosophy, and gender studies of science, Sarah S. Richardson uncovers how gender has helped to shape the research practices, questions asked, theories and models, and descriptive language used in sex chromosome research. From the earliest theories of chromosomal sex determination, to the mid-century hypothesis of the aggressive XYY supermale, to the debate about Y chromosome degeneration, to the recent claim that male and female genomes are more different than those of humans and chimpanzees, Richardson shows how cultural gender conceptions influence the genetic science of sex. Richardson shows how sexual science of the past continues to resonate, in ways both subtle and explicit, in contemporary research on the genetics of sex and gender. With the completion of the Human Genome Project, genes and chromosomes are moving to the center of the biology of sex. Sex Itself offers a compelling argument for the importance of ongoing critical dialogue on how cultural conceptions of gender operate within the science of sex.

Author : National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on Human Genome Diversity
Publisher : National Academies Press
Page : 101 pages
File Size : 41,7 Mb
Release : 1998-01-19
Category : Science
ISBN : 9780309184748

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Evaluating Human Genetic Diversity by National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on Human Genome Diversity Pdf

This book assesses the scientific value and merit of research on human genetic differencesâ€"including a collection of DNA samples that represents the whole of human genetic diversityâ€"and the ethical, organizational, and policy issues surrounding such research. Evaluating Human Genetic Diversity discusses the potential uses of such collection, such as providing insight into human evolution and origins and serving as a springboard for important medical research. It also addresses issues of confidentiality and individual privacy for participants in genetic diversity research studies.