The Molecular Biology Of Cell Determination And Cell Differentiation

Author : Leon W. Browder
Publisher : Springer Science & Business Media
Page : 448 pages
File Size : 50,8 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461568179

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The Molecular Biology of Cell Determination and Cell Differentiation by Leon W. Browder Pdf

This series was established to create comprehensive treatises on specific topics in developmental biology. Such volumes serve a useful role in developmental biology, which is a very diverse field that receives contributions from a wide variety of disciplines. This series is a meeting ground for the various practi tioners of this science, facilitating an integration of heterogeneous information on specific topics. Each volume is comprised of chapters selected to provide the conceptual basis for a comprehensive understanding of its topic as well as an analysis of the key experiments upon which that understanding is based. The specialist in any aspect of developmental biology should understand the experimental back ground of the specialty and be able to place that body of information in context, in order to ascertain where additional research would be fruitful. The creative process then generates new experiments. This series is intended to be a vital link in that ongoing process of learning and discovery.

Author : Norman Maclean,Brian Keith Hall
Publisher : CUP Archive
Page : 260 pages
File Size : 43,7 Mb
Release : 1987-08-13
Category : Science
ISBN : 0521349648

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Cell Commitment and Differentiation by Norman Maclean,Brian Keith Hall Pdf

This book is about how cells differentiate; it describes the way in which cells in animal and plant bodies take on their specialised fates.

Author : Paul B. Fisher
Publisher : CRC Press
Page : 176 pages
File Size : 51,7 Mb
Release : 1990-08-27
Category : Medical
ISBN : 0849349478

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Mechanisms of Differentiation by Paul B. Fisher Pdf

Significant recent advances in cell culture technology now permit a detailed biochemical and molecular analysis of differentiation in both normal and tumor cells. These studies are important in attempting to understand the complex factors involved in normal growth and development, as well as the abnormalities associated with carcinogenesis. Mechanisms of Differentiation, Volumes I and II, is comprised of review chapters addressing various topics of current interest in this important area of research. Topics discussed include genes controlling differentiation, changes in gene expression during differentiation, induction of differentiation, induction of differentiation as a mode of action of chemotherapeutic agents, and the effect of cell shape, growth factors and differentiation modulating agents on the differentiated cell phenotype. Mechanisms of Differentiation is valuable to researchers involved in differentiation and development, carcinogenesis, cell biology, chemotherapy, and immunology.

Author : Hiten D. Madhani
Publisher : CSHL Press
Page : 124 pages
File Size : 43,5 Mb
Release : 2007
Category : Biological models
ISBN : 9780879697389

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From a to [alpha] by Hiten D. Madhani Pdf

From a to&alphais a short supplemental textbook that uses control of yeast mating type as a model for many aspects of cell determination in general. Topics covered include gene silencing; genetic recombination; differentiation; combinatorial gene regulation; mRNA transport to establish asymmetric cell division; signal transduction; evolution of genetic networks; and various aspects of cell biology, including action of cytoskeleton and bud site selection. The book includes a foreword by Mark Ptashne, author of A Genetic Switch.

Author : Sally A. Moody
Publisher : Elsevier
Page : 661 pages
File Size : 44,6 Mb
Release : 1998-10-29
Category : Science
ISBN : 9780080528786

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Cell Lineage and Fate Determination by Sally A. Moody Pdf

Cell Lineage and Fate Determination provides a comprehensive view of the mechanisms regulating cell lineage and fate determination in an effort to understand how the fertilized egg is transformed into a complex of specialized tissues. It presents basic information on eight different animal models and recent developmental biological research done in each model. The book provides a focused forum presenting key information for researchers studying various aspects of developmental and cellular biology. Extensive use of tables and black-and-white and color figures helps illustrate each model. The book concludes by discussing future goals for bringing cellular, molecular, and genetic research to clinical applications and tissue replacement therapies. Key Features* Presents eight different animal models* Provides a focused forum on cell fate determination that provides comprehensive and key information for researchers* Illustrates the transitional relationship between researchers and clinicians* Includes the extensive use of tables and color figures

Author : Ole A. Schjeide,Jean De Vellis
Publisher : Unknown
Page : 636 pages
File Size : 48,6 Mb
Release : 1970
Category : Cell differentiation
ISBN : UCAL:$B221434

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Cell Differentiation by Ole A. Schjeide,Jean De Vellis Pdf

Author : W. J. Gehring
Publisher : Springer Science & Business Media
Page : 323 pages
File Size : 48,7 Mb
Release : 2013-06-29
Category : Science
ISBN : 9783540358039

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Genetic Mosaics and Cell Differentiation by W. J. Gehring Pdf

The relationship of cell lineage and differentiation is one of the most intriguing problems in developmental biology. In most higher organisms, the analysis of the cell lineage has to rely on indirect methods. Only in the most suitable systems, like the nematodes, can the pattern of cell division be determined by direct observation under the microscope. In cases where this is not possible, the fate of the cells has to be examined by using cell markers. Most suitable for this purpose are genetic markers, provided that they do not interfere with the developmental pathway to be studied. However, suitable genetic markers and techniques for generating genetic mosaics are available in a few organisms only. Therefore, this volume is largely concerned with Drosophila and the mouse, which have been studied most extensively. In 1929 STURTEVANT introduced the analysis of gynandromorphs into devel opmental genetics. However, this important contribution remained largely unnoticed until the late sixties, when the potential of this technique for deter mining embryonic fate maps and the number of primordial cells was exploited, and the methodology extended to the mapping of mutational foci. Mitotic recombination was demostrated by STER:-

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 51,5 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf

Author : Lutz Nover,Martin Luckner,Benno Parthier
Publisher : Unknown
Page : 650 pages
File Size : 47,7 Mb
Release : 1978
Category : Cell differentiation
ISBN : OCLC:636676617

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Cell Differentiation by Lutz Nover,Martin Luckner,Benno Parthier Pdf

Author : J. Reinert,H. Holtzer
Publisher : Springer
Page : 356 pages
File Size : 41,6 Mb
Release : 1975
Category : Science
ISBN : UOM:39015004381870

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Cell Cycle and Cell Differentiation by J. Reinert,H. Holtzer Pdf

Myogenesis: a cell lineage interpretation; The organization of red cell differentiation; The cell cycle, cell lineage, and neuronal specificity; Neurogenesis and the cell cycle; The cell cycle and cell differentiation in the Drosophila ovary; The cell cycle and cellular differentiation in insects; Nuclear transplantation and the cyclic reprogramming of gene expression; Morphogenesis during the cell cycle of the prokayote, caulobacter crescentus; Cell division and the determination phase of cytodifferentiation in plants; The cell cycle and tumorigenesis in plants; Cell cycle and liver function; Histones, differentiation, and the cell cycle; Cell changes in neurospora.

Author : Joan Abbott
Publisher : Springer
Page : 163 pages
File Size : 53,8 Mb
Release : 2013-11-11
Category : Science
ISBN : 9783662350898

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The Stability of the Differentiated State by Joan Abbott Pdf

Author : Anonim
Publisher : Elsevier
Page : 509 pages
File Size : 47,6 Mb
Release : 2003-12-18
Category : Science
ISBN : 0080546161

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Differentiation of Embryonic Stem Cells by Anonim Pdf

This volume covers all aspects of embryonic stem cell differentiation, including mouse embryonic stem cells, mouse embryonic germ cells, monkey and human embryonic stem cells, and gene discovery. * Early commitment steps and generation of chimeric mice * Differentiation to mesoderm derivatives * Gene discovery by manipulation of mouse embryonic stem cells

Author : T. S. Okada
Publisher : Unknown
Page : 248 pages
File Size : 43,5 Mb
Release : 1991
Category : Science
ISBN : MINN:31951D005038699

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Transdifferentiation by T. S. Okada Pdf

Is it possible that fully differential cells, cells that have acquired specialized functions and perhaps have lost some general properties, can change their nature, becoming cells of another type? Professor Okada has studied this problem extensively and introduced the term "transdifferentiation" to describe the phenomenon. Transdifferentiation is extremely controversial, since it challenges a number of biological orthodoxies. If transdifferentiation really does occur, the process of development and differentiation must be much more flexible than biologists have generally believed. In this book, the author brings together a vast amount of experimental evidence and examines it critically. This discussion clearly establishes that there is a real phenomenon to be explained and that the explanation forces us to change our understanding of a number of basic biological processes. Much of the evidence examined is derived from studies of cell biology but increasingly it has become possible to examine the process at the molecular level. Studies of gene expression provide several promising perspectives on the process of transdifferentiation. Although this monograph focuses on some rather specialized experiments and discusses questions of definition, the phenomenon is so compelling and is of such fundamental importance that postgraduates and researchers in developmental and cell biology, as well as scientists in basic cancer and eye research, will find it equally interesting.

Author : Rafal P. Piprek
Publisher : Springer
Page : 434 pages
File Size : 52,5 Mb
Release : 2016-06-14
Category : Science
ISBN : 9783319319735

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Molecular Mechanisms of Cell Differentiation in Gonad Development by Rafal P. Piprek Pdf

This book presents the current state of knowledge on the origin and differentiation of cell lines involved in the development of the vertebrate male and female gonads with particular emphasis on the mouse. It also discusses the processes leading to the testis- and ovary-specific structures and functions. The individual chapters review the origin and differentiation of the somatic cells of the genital ridges; the formation and migration of primordial germ cells in mouse and man; the gonadal supporting cell lineage and mammalian sex determination; differentiation of Sertoli and granulosa cells; mesonephric cell migration into the gonads and vascularization; origin and differentiation of androgen-producing cells in the gonads; germ cell commitment to the oogenic versus spermatogenic pathway and the role of retinoic acid; ovarian folliculogenesis; control of oocyte growth and development by intercellular communication within the follicular niche; biology of the Sertoli cell in the fetal, pubertal and adult mammalian testis; mechanisms regulating spermatogonial differentiation; stem cells in mammalian gonads; the role of microRNAs in cell differentiation during gonad development; human sex development and its disorders; as well as methods for the study of gonadal development.

Author : Marketta Karkinen-Jaaskelainen
Publisher : Elsevier
Page : 432 pages
File Size : 44,6 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780323150552

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Cell Interactions in Differentiation by Marketta Karkinen-Jaaskelainen Pdf

Cell Interactions in Differentiation is a collection of papers presented at the Sixth Sigrid Jusélius Foundation Symposium held in Helsinki, Finland, in August 1976. Contributors discuss cell interactions during differentiation, particularly referring to the problem of embryonic induction. They also consider how a cell becomes adjusted to the synchronized development of an entire multicellular organism, so as to express its genetic information at a strictly controlled time and place. This volume is organized into five sections encompassing 30 chapters and begins with an overview of embryonic cells and their two fundamental properties. Cells are not necessarily predetermined and can be experimentally diverted from their normal developmental pathway, and those within an embryonic organism require extrinsic messages to express their developmental capacities. The next chapters focus on early determinative events in embryogenesis, touching on topics such as the genetic aspects of cell type determination, interactions between embryonic cells during the early development of the mouse, and the differentiation of teratocarcinoma stem cells in vitro. The reader is then introduced to positional information and morphogenetic signals; the biological ""specificity"" of morphogenetic tissue interactions; and the molecular mechanisms underlying cell contact interactions. The remaining chapters explore some of the most important conceptual and methodological approaches to the problems of cell-cell recognition and the integration of cells into multicellular systems. This book will be of interest to scientists and investigators in developmental biology and related fields.