The Myelodysplastic Syndromes

Author : Aziz Nazha
Publisher : Springer Nature
Page : 179 pages
File Size : 52,7 Mb
Release : 2020-08-13
Category : Medical
ISBN : 9783030518783

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Diagnosis and Management of Myelodysplastic Syndromes by Aziz Nazha Pdf

Myelodysplastic syndromes (MDS) are a group of clonal disorders characterized by pancytopenias and the risk of progression to acute myeloid leukemia. The diagnosis of MDS can be challenging, while the outcomes of MDS patients vary widely. This book provides a concise yet comprehensive overview of MDS. The book begins by reviewing the diagnostic workup of MDS, with a specific focus on the 2016 WHO criteria for MDS diagnosis, and the biology and pathophysiology of the disease. The text then presents the molecular landscape of MDS and its impact on disease diagnosis, prognosis, and treatment decisions. The book continues by profiling different prognostic models of MDS and concludes with a thorough review of treatment algorithms for lower and higher-risk MDS, as well as the use of hematopoietic stem cell transplant to combat the disease. Written by experts in the field, Diagnosis and Management of Myelodysplastic Syndromes: A Clinical Guide is a valuable resource for clinicians, practitioners, and researchers who are interested in MDS. The text also features over 100 illustrations, photographs, and tables.

Author : M. Extermann
Publisher : Karger Medical and Scientific Publishers
Page : 179 pages
File Size : 51,7 Mb
Release : 2013-01-18
Category : Medical
ISBN : 9783318023077

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Cancer and Aging by M. Extermann Pdf

Cancer is clearly an age-related disease. Recent research in both aging and cancer has demonstrated the complex interaction between the two phenomena. This affects a wide spectrum of research and practice, anywhere from basic research to health care organization. Core examples of these close associations are addressed in this book. Starting with basic research, the first chapters cover cancer development, mTOR inhibition, senescent cells altering the tumor microenvironment, and immune senescence affecting cancer vaccine response. Taking into account the multidisciplinarity of geriatric oncology, several chapters focus on geriatric and oncologic aspects in patient assessment, treatment options, nursing and exercise programs. The book is rounded off by a discussion on the impact of the metabolic syndrome illustrating the interactions between comorbidity and cancer and a chapter on frailty.This book provides the reader with insights that will hopefully foster his or her reflection in their own research and practice to further the development of this most exciting field. Given the aging of the population worldwide and the high prevalence of cancer, it is essential reading not only for oncologists and geriatricians but for all health practitioners.

Author : Ronald Hoffman
Publisher : Unknown
Page : 2821 pages
File Size : 49,5 Mb
Release : 2005
Category : Blood
ISBN : 0443066280

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Hematology by Ronald Hoffman Pdf

Author : Jason Gotlib,Lenn Fechter
Publisher : Jones & Bartlett Publishers
Page : 204 pages
File Size : 55,7 Mb
Release : 2015-04-24
Category : Myelodysplastic syndromes
ISBN : 9781284022544

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100 Questions & Answers about Myelodysplastic Syndromes by Jason Gotlib,Lenn Fechter Pdf

Newly revised and updated, 100 Questions & Answers About Myelodysplastic Syndromes provides authoritative and practical answers to the most common questions asked by patients and their loved ones. What is myelodysplastic syndromes (MDS)? What causes MDS? Is MDS hereditary, and will I give it to my children? Written by experts in the field, and with commentary from actual patients, this guide is the only text available to provide both the doctor's and patient's views.100 Questions & Answers About Myelodysplastic Syndromes is an invaluable resource for anyone struggling with the medical, physical, and emotional turmoil of this disease.

Author : Nicolaus Kröger,Mohamad Mohty,Carlo Dufour
Publisher : Unknown
Page : 688 pages
File Size : 41,9 Mb
Release : 2020-10-08
Category : Medical
ISBN : 1013273672

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The EBMT Handbook by Nicolaus Kröger,Mohamad Mohty,Carlo Dufour Pdf

This Open Access edition of the European Society for Blood and Marrow Transplantation (EBMT) handbook addresses the latest developments and innovations in hematopoietic stem cell transplantation and cellular therapy. Consisting of 93 chapters, it has been written by 175 leading experts in the field. Discussing all types of stem cell and bone marrow transplantation, including haplo-identical stem cell and cord blood transplantation, it also covers the indications for transplantation, the management of early and late complications as well as the new and rapidly evolving field of cellular therapies. This book provides an unparalleled description of current practices to enhance readers' knowledge and practice skills. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.

Author : Peter L. Greenberg
Publisher : Cambridge University Press
Page : 344 pages
File Size : 45,8 Mb
Release : 2011-02-17
Category : Medical
ISBN : 1139447076

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Myelodysplastic Syndromes by Peter L. Greenberg Pdf

Myelodysplastic Syndromes was first published in 2006, and continues to stand out as the definitive text on the genetics, pathophysiology, and clinical management of this wide range of syndromes. It remains a major reference on all aspects of the clinical classification underlying pathogenetic mechanisms and treatment of the myelodysplastic syndromes. Authored by international experts, the book provides an assessment of the subject's status and a variety of advances in the field. The chapters cover all aspects of the myelodysplastic syndromes, from an in-depth analysis of the multifactorial nature of this disease, including a careful assessment of stromal, immunological and stem cell abnormalities, to a review of recent molecular and cytogenetic discoveries and insights. This book will be a valuable resource to clinicians and researchers who wish to learn more about myelodysplastic syndromes.

Author : Judit Várkonyi
Publisher : Springer Science & Business Media
Page : 290 pages
File Size : 54,5 Mb
Release : 2011-03-23
Category : Medical
ISBN : 9789400704404

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The Myelodysplastic Syndromes by Judit Várkonyi Pdf

Myelodysplastic syndromes (MDS) are the most common hematological malignancies involving mostly the elderly population. The major morbidity relates to patients’ symptomatic cytopenias.MDS was previously named as “preleukemia “ or “ smoldering leukemia” as the lack of terminal cells in MDS and because about 25% of all cases progresses into acute myeloid leukemia. According to various reports the annual incidence of MDS ranges widely from 2-12 per 100.000, increasing to 30-50 cases per 100.000 among persons aged 70 or older. It is believed that the true incidence of MDS have been underestimated however it seems to be comparable to that for multiple myeloma and chronic lymphocytic leukemia. In the past decade much progress had been made; we know more on the disease pathology, there is more emphasis on the care and more targeted therapy had been invested. Athors provide updated knowledge in this book on all clinically important aspects of the disease. Hot topics of our days are discussed in chapters by outstanding and well known scientists from all over the world. We would offer this product both for medical students and postgraduates as well as for all who are interested in this very exciting and fast progressing field of hematology. With this work authors should call attention on the disease for decision makers in healt care systems as well.

Author : John Bennett
Publisher : CRC Press
Page : 558 pages
File Size : 43,7 Mb
Release : 2002-05-21
Category : Medical
ISBN : 9780203908853

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The Myelodysplastic Syndromes by John Bennett Pdf

This reference provides a comprehensive overview of the latest research detailing the etiology, epidemiology, treatment, and detection of myelodysplastic syndromes (MDS)-identifying effective therapeutic regimens, adverse environmental and genetic factors, and efficient modalities of supportive care that improve patient survival and enhance quality

Author : Arthur Hadley
Publisher :
Page : 27 pages
File Size : 52,6 Mb
Release : 2019-09-23
Category : Medical
ISBN : 8210379456XXX

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Myelodysplastic Syndrome (MDS) by Arthur Hadley Pdf

Being diagnosed with Myelodysplastic syndrome can be daunting and unexpected. Many people have never heard of the blood/ bone marrow disorder MDS. I have written this short MDS book to help you quickly understand some of the jargon and medical issues relating to Myelodysplastic syndromes. This book will cover diagnosis, symptoms, treatments and more. If you have any of the following questions then this guide may help you understand some aspect of MDS what does MDS stand for? What is Myelodysplastic Syndrome? How MDS is diagnosed? How does MDS typically affect the body? What MDS treatments are available? Is MDS cancer? Does MDS turn into AML? Is MDS genetic? There is also a section which covers how to maintain a healthy lifestyle and understanding a person's limitations when living with MDS. The effects of common symptoms of anaemia, low blood cell counts (white blood cell types and red blood cells) and low platelets and how to counter their effects with growth factors and blood transfusions. Ideal for MDS sufferers and their caregivers / family. Also included are references to sites that you may find useful. Please note, I am not a medical professional, but have had a family member with this condition and help care for them over many years. All the best, Arthur Hadley

Author : Anonim
Publisher : ScholarlyEditions
Page : 66 pages
File Size : 51,7 Mb
Release : 2012-01-09
Category : Medical
ISBN : 9781464904011

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Myelodysplastic Syndromes: New Insights for the Healthcare Professional: 2011 Edition by Anonim Pdf

Myelodysplastic Syndromes: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Myelodysplastic Syndromes in a concise format. The editors have built Myelodysplastic Syndromes: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Myelodysplastic Syndromes in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Myelodysplastic Syndromes: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Author : P. Dyer,M.L. Arellano
Publisher : Karger Medical and Scientific Publishers
Page : 79 pages
File Size : 51,9 Mb
Release : 2021-02-12
Category : Medical
ISBN : 9783318068733

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Fast Facts: Myelodysplastic Syndromes by P. Dyer,M.L. Arellano Pdf

Myelodysplastic syndromes (MDS) are a group of clonal myeloid blood disorders that affect older people. As the global population ages, the incidence of these disorders is increasing. As such, healthcare professionals need to be aware of MDS as a possible diagnosis and know how to identify those patients whose condition is most likely to transform to acute myeloid leukemia (AML). Fast Facts: Myelodysplastic Syndromes explains how these disorders are classified, how they present and how prognosis and the risk of transformation to AML are assessed. It also outlines the most appropriate management options for patients of different ages, together with an overview of the latest research under way to further understand MDS and how to treat it. This highly readable resource is the ideal primer on MDS for all members of the multidisciplinary team involved in the care of patients with MDS, including hematologists, hematology trainees, clinical nurse specialists and primary care providers. Table of Contents: • Epidemiology and etiology • Pathogenesis and presentation • Diagnosis and classification • Management • Supporting patients with MDS

Author : Chaim Hershko
Publisher : Springer Science & Business Media
Page : 275 pages
File Size : 47,8 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461505938

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Iron Chelation Therapy by Chaim Hershko Pdf

Within the last few years, iron research has yielded exciting new insights into the under standing of normal iron homeostasis. However, normal iron physiology offers little protec tion from the toxic effects of pathological iron accumulation, because nature did not equip us with effective mechanisms of iron excretion. Excess iron may be effectively removed by phlebotomy in hereditary hemochromatosis, but this method cannot be applied to chronic anemias associated with iron overload. In these diseases, iron chelating therapy is the only method available for preventing early death caused mainly by myocardial and hepatic iron toxicity. Iron chelating therapy has changed the quality of life and life expectancy of thalassemic patients. However, the high cost and rigorous requirements of deferoxamine therapy, and the significant toxicity of deferiprone underline the need for the continued development of new and improved orally effective iron chelators. Such development, and the evolution of improved strategies of iron chelating therapy require better understanding of the pathophysiology of iron toxicity and the mechanism of action of iron chelating drugs. The timeliness of the present volume is underlined by several significant develop ments in recent years. New insights have been gained into the molecular basis of aberrant iron handling in hereditary disorders and the pathophysiology of iron overload (Chapters 1-5).

Author : Ota Fuchs
Publisher : Unknown
Page : 212 pages
File Size : 44,6 Mb
Release : 2016-09-07
Category : Electronic
ISBN : 9789535125860

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Myelodysplastic Syndromes by Ota Fuchs Pdf

Author : Attilio Orazi,Dennis P. O'Malley,Daniel A. Arber
Publisher : Cambridge University Press
Page : 133 pages
File Size : 40,8 Mb
Release : 2006-07-20
Category : Medical
ISBN : 9781139455527

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Illustrated Pathology of the Bone Marrow by Attilio Orazi,Dennis P. O'Malley,Daniel A. Arber Pdf

This book provides a highly illustrated and comprehensive account of the diseases of the human bone marrow. It will help experienced clinicians and those in training to answer the practical diagnostic questions that arise during the routine analysis of bone marrow core biopsy specimens. Throughout the text, histologic interpretation is integrated with clinical and laboratory findings. Emphasis is placed on the evaluation of peripheral blood, aspirate smear, clot section and core biopsy, as well as ancillary techniques including flow cytometry and immunohistochemistry in the diagnosis of hematologic disorders of the marrow. The text is illustrated with numerous color figures, charts and tables, and descriptions of real case situations using the most up-to-date classification systems. Illustrated Pathology of Bone Marrow should be read by all pathologists, hematologists and laboratory technicians involved in the analysis of bone marrow specimens.

Author : H. Joachim Deeg,David T. Bowen,Steven D. Gore,Torsten Haferlach,Michelle M. Le Beau,Charlotte Niemeyer
Publisher : Springer Science & Business Media
Page : 245 pages
File Size : 40,9 Mb
Release : 2013-07-08
Category : Medical
ISBN : 9783642362293

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Myelodysplastic Syndromes by H. Joachim Deeg,David T. Bowen,Steven D. Gore,Torsten Haferlach,Michelle M. Le Beau,Charlotte Niemeyer Pdf

The diagnosis of myelodysplastic syndromes (MDS), a heterogeneous group of clonal hematopoietic disorders, is being made with increasing frequency over the past decade owing to increased recognition, improved understanding, and an aging population. This book, completely updated since the first edition, summarizes in a concise and focused way the current knowledge of all aspects of MDS. Clinical presentation, etiology, epidemiology, molecular biology, classification, and staging are all discussed. Clear guidance is provided on diagnosis and differential diagnosis, and treatment strategies are explained in detail, including administration of hematopoietic growth factors, biologically based treatment, hematopoietic stem cell transplantation, and supportive care. Additional chapter is devoted to MDS in children. This practically oriented book will be of value to a broad spectrum of students and practitioners in the field.