The Resonant Recognition Model Of Macromolecular Bioactivity

Author : Irena Cosic
Publisher : Birkhäuser
Page : 154 pages
File Size : 47,8 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783034874755

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The Resonant Recognition Model of Macromolecular Bioactivity by Irena Cosic Pdf

Biological processes in any living organism are based on selective interactions be tween particular biomolecules. In most cases, these interactions involve and are driven by proteins, which are the main conductors of any life process within the organism. The physical nature of these interactions is still not well known. This book presents an entirely new approach to analysis of biomolecular in teractions, in particular protein-protein and protein-DNA interactions, based on the assumption that these interactions are electromagnetic in nature. This new ap proach is the basis of the Resonant Recognition Model (RRM), which was devel oped over the last 15 years. Certain periodicities within the distribution of energies of delocalised electrons along a protein molecule are crucial to the protein's biological function, i.e. inter action with its target. If protein conductivity were introduced, then charges mov ing through the protein backbone might produce electromagnetic irradiation or ab sorption with spectral characteristics corresponding to energy distribution along the protein. The RRM is capable of calculating these spectral characteristics, which we hypothesized would be in the range of the infrared and visible light. These characteristics were confirmed with frequency characteristics obtained ex perimentally for certain light-induced biological processes.

Author : Irena Cosic
Publisher : Unknown
Page : 160 pages
File Size : 40,7 Mb
Release : 1997-04-01
Category : Electronic
ISBN : 3034874766

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The Resonant Recognition Model of Macromolecular Bioactivity by Irena Cosic Pdf

Author : Anirban Bandyopadhyay,Kanad Ray
Publisher : Springer Nature
Page : 368 pages
File Size : 44,8 Mb
Release : 2020-10-29
Category : Technology & Engineering
ISBN : 9789811572531

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Rhythmic Oscillations in Proteins to Human Cognition by Anirban Bandyopadhyay,Kanad Ray Pdf

This book explores various aspects of biophysics, from neurobiology to quantum biology and the consciousness of human beings and in the universe. It examines eight different areas of natural intelligence, ranging from time crystals found in chemical biology, to the vibrations and the resonance of proteins, and also discusses hierarchical communication in various biological systems. Written by senior and experts in the field in language that is lucid and easy to understand, it is a valuable reference resource for researchers and practitioners in academia and industry.

Author : Wei Zhang,Ilya Shmulevich
Publisher : Springer Science & Business Media
Page : 426 pages
File Size : 43,8 Mb
Release : 2007-12-26
Category : Science
ISBN : 9780387262888

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Computational and Statistical Approaches to Genomics by Wei Zhang,Ilya Shmulevich Pdf

The second edition of this book adds eight new contributors to reflect a modern cutting edge approach to genomics. It contains the newest research results on genomic analysis and modeling using state-of-the-art methods from engineering, statistics, and genomics. These tools and models are then applied to real biological and clinical problems. The book’s original seventeen chapters are also updated to provide new initiatives and directions.

Author : Igor F. Tsigelny
Publisher : Internat'l University Line
Page : 540 pages
File Size : 50,7 Mb
Release : 2002
Category : Science
ISBN : 096368177X

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Protein Structure Prediction by Igor F. Tsigelny Pdf

Author : P. Jackson,J.T. Gallagher
Publisher : Birkhäuser
Page : 424 pages
File Size : 44,6 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783034873888

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A Laboratory Guide to Glycoconjugate Analysis by P. Jackson,J.T. Gallagher Pdf

18. 2 Principle of FACE/Gel Retardation Assay . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 349 18. 3 Labelling of Oligosaccharides with ANTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 350 18. 4 Screening of Carbohydrate Ligands for Proteins . . . . . . . . . . . . . . . . . . . . . . . . . . . 352 18. 5 Measurement of Binding Constant for the Interaction Between Protein and ANTS-Labelled Carbohydrate . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 355 18. 6 Measurement of Binding Constant for the Interaction Between Protein and Native Carbohydrate . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 357 References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 360 ~ The Application of Capillary Affinity Electrophoresis to the Analysis _ of Carbohydrate-Protein Interactions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 361 19. 1 Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 361 19. 2 Principle of CAE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 363 19. 3 Determination of Association Constants . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 364 19. 4 Technical Procedures . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 366 General considerations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 366 19. 5 Limitations of the Technique . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 370 19. 6 Application of CAE to the Analysis of Carbohydrate-Protein Interactions . . . . . . 371 19. 7 Conclusions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 375 References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 377 20. 1 Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 379 Definitions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 380 20. 2 Technical Procedures . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 381 20. 3 Sample Detection and Sample Recovery . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 389 Autoradiography and staining . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 389 Sample detection by blotting . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 389 Semipreparative ACE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 390 20. 4 Analysis of Data . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 391 Measuring sample mobilities - calculating a retardation coefficient . . . . . . . . . . . . 391 Graphical analysis of data . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 392 Interpreting ACE patterns . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 393 Reverse ACE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 395 20. 5 Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 397 Acknowledgements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 398 References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 398 Subject Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 399 XII List of Contributors Nebojsa Avdalovic John T. Gallagher Dionex Corporation Cancer Research Campaign Department of Medical Oncology 445 Lakeside Drive University of Manchester Sunnyvale, CA 94086 Christie CRC Research Centre Klaus Biemann Wilmslow Road Department of Chemistry Manchester M20 4BX Massachusetts Institute of Technology UK Cambridge, MA 02139-4307 USA Geoffrey R.

Author : Metin Akay
Publisher : John Wiley & Sons
Page : 317 pages
File Size : 53,8 Mb
Release : 2006-10-09
Category : Medical
ISBN : 9780470052181

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Genomics and Proteomics Engineering in Medicine and Biology by Metin Akay Pdf

Current applications and recent advances in genomics and proteomics Genomics and Proteomics Engineering in Medicine and Biology presents a well-rounded, interdisciplinary discussion of a topic that is at the cutting edge of both molecular biology and bioengineering. Compiling contributions by established experts, this book highlights up-to-date applications of biomedical informatics, as well as advancements in genomics-proteomics areas. Structures and algorithms are used to analyze genomic data and develop computational solutions for pathological understanding. Topics discussed include: Qualitative knowledge models Interpreting micro-array data Gene regulation bioinformatics Methods to analyze micro-array Cancer behavior and radiation therapy Error-control codes and the genome Complex life science multi-database queries Computational protein analysis Tumor and tumor suppressor proteins interactions

Author : Xiangdong Wang
Publisher : Springer Science & Business Media
Page : 396 pages
File Size : 40,7 Mb
Release : 2013-01-26
Category : Science
ISBN : 9789400758117

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Bioinformatics of Human Proteomics by Xiangdong Wang Pdf

“Bioinformatics of Human Proteomics” discusses the development of methods, techniques and applications in the field of protein bioinformatics, an important direction in bioinformatics. It collects contributions from expert researchers in order to provide a practical guide to this complex field of study. The book covers the protein interaction network, drug discovery and development, the relationship between translational medicine and bioinformatics, and advances in proteomic methods, while also demonstrating important bioinformatics tools and methods available today for protein analysis, interpretation and predication. It is intended for experts or senior researchers in the fields of clinical research-related biostatistics, bioinformatics, computational biology, medicine, statistics, system biology, molecular diagnostics, biomarkers, or drug discovery and development. Dr.Xiangdong Wang works as a distinguished professor of Respiratory Medicine at Fudan University, Shanghai, China. He serves as Director of Biomedical Research Center, Fudan University Zhongshan Hospital and adjunct professor of Clinical Bioinformatics at Lund University, Sweden. His main research is focused on the role of clinical bioinformatics in the development of disease-specific biomarkers and dynamic network biomarkers, the molecular mechanism of organ dysfunction and potential therapies.

Author : Mian Long
Publisher : Springer Science & Business Media
Page : 2385 pages
File Size : 52,8 Mb
Release : 2013-02-11
Category : Technology & Engineering
ISBN : 9783642293054

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World Congress on Medical Physics and Biomedical Engineering May 26-31, 2012, Beijing, China by Mian Long Pdf

The congress’s unique structure represents the two dimensions of technology and medicine: 13 themes on science and medical technologies intersect with five challenging main topics of medicine to create a maximum of synergy and integration of aspects on research, development and application. Each of the congress themes was chaired by two leading experts. The themes address specific topics of medicine and technology that provide multiple and excellent opportunities for exchanges.

Author : Vijay Nath,J. K. Mandal
Publisher : Springer Nature
Page : 1078 pages
File Size : 47,9 Mb
Release : 2020-09-19
Category : Technology & Engineering
ISBN : 9789811555466

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Proceedings of the Fourth International Conference on Microelectronics, Computing and Communication Systems by Vijay Nath,J. K. Mandal Pdf

This book presents high-quality papers from the Fourth International Conference on Microelectronics, Computing & Communication Systems (MCCS 2019). It discusses the latest technological trends and advances in MEMS and nanoelectronics, wireless communication, optical communication, instrumentation, signal processing, image processing, bioengineering, green energy, hybrid vehicles, environmental science, weather forecasting, cloud computing, renewable energy, RFID, CMOS sensors, actuators, transducers, telemetry systems, embedded systems and sensor network applications. It includes papers based on original theoretical, practical and experimental simulations, development, applications, measurements and testing. The applications and solutions discussed here provide excellent reference material for future product development.

Author : Hiroshi Motoda,Zhaohui Wu,Longbing Cao,Osmar Zaiane,Min Yao,Wei Wang
Publisher : Springer
Page : 556 pages
File Size : 41,5 Mb
Release : 2013-12-16
Category : Computers
ISBN : 9783642539176

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Advanced Data Mining and Applications by Hiroshi Motoda,Zhaohui Wu,Longbing Cao,Osmar Zaiane,Min Yao,Wei Wang Pdf

The two-volume set LNAI 8346 and 8347 constitutes the thoroughly refereed proceedings of the 9th International Conference on Advanced Data Mining and Applications, ADMA 2013, held in Hangzhou, China, in December 2013. The 32 regular papers and 64 short papers presented in these two volumes were carefully reviewed and selected from 222 submissions. The papers included in these two volumes cover the following topics: opinion mining, behavior mining, data stream mining, sequential data mining, web mining, image mining, text mining, social network mining, classification, clustering, association rule mining, pattern mining, regression, predication, feature extraction, identification, privacy preservation, applications, and machine learning.

Author : David F. Mayor
Publisher : Elsevier Health Sciences
Page : 404 pages
File Size : 44,9 Mb
Release : 2007-06-12
Category : Medical
ISBN : 9780443063695

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Electroacupuncture by David F. Mayor Pdf

This book presents an overview of the theoretical foundations of electroacupuncture, together with experimental and clinical evidence for the efficacy of electroacupuncture in its various forms. It also provides guidance on the effective clinical practice of electroacupuncture, illustrated with informative case histories. It serves as an excellent introduction on the subject, covering all the key information a beginning practitioner would need to know, as well as exploring avenues for advanced practice. The accompanying CD-ROM is an ideal research tool, providing searchable chapters from the book as well as an extensive database of more than 8,000 clinical trials that can be accessed via the CD-ROM or through a companion website. liThe first comprehensive overview of modern acupuncture methods for 20 years/liliClear and accessible guide to an increasingly popular form of acupuncture practice/liliDesigned for both technically and non-technically minded readers/liliProvides a basis for immediate practical application in a variety of clinical situations/liliCase studies from expert practitioners in the field illustrate the variety of possible approaches/liliOnly book on the subject to offer both practical suggestions and thorough exploration of the research behind the practice/liliBridges the gap between traditional and modern scientific approaches to acupuncture/liliSifts and sorts what is often confusing or highly technical material into manageable and practical information/liliIncludes an interactive CD-ROM containing over 15,000 references/liliFully searchable database of more than 8,000 clinical studies is accessible via the accompanying CD-ROM and website/liliDatabase includes material from thousands of studies never before available in English - translated from Chinese, Russian, Ukrainian and other European languages/liliComprehensive glossary defines and explains important concepts

Author : Anonim
Publisher : Unknown
Page : 128 pages
File Size : 46,5 Mb
Release : 2024-07-02
Category : Electronic
ISBN : 9789814475129

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Analysis of Biological Data by Anonim Pdf

Author : Laura M. Roa Romero
Publisher : Springer Science & Business Media
Page : 1978 pages
File Size : 53,8 Mb
Release : 2013-10-01
Category : Technology & Engineering
ISBN : 9783319008462

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XIII Mediterranean Conference on Medical and Biological Engineering and Computing 2013 by Laura M. Roa Romero Pdf

The general theme of MEDICON 2013 is "Research and Development of Technology for Sustainable Healthcare". This decade is being characterized by the appearance and use of emergent technologies under development. This situation has produced a tremendous impact on Medicine and Biology from which it is expected an unparalleled evolution in these disciplines towards novel concept and practices. The consequence will be a significant improvement in health care and well-fare, i.e. the shift from a reactive medicine to a preventive medicine. This shift implies that the citizen will play an important role in the healthcare delivery process, what requires a comprehensive and personalized assistance. In this context, society will meet emerging media, incorporated to all objects, capable of providing a seamless, adaptive, anticipatory, unobtrusive and pervasive assistance. The challenge will be to remove current barriers related to the lack of knowledge required to produce new opportunities for all the society, while new paradigms are created for this inclusive society to be socially and economically sustainable, and respectful with the environment. In this way, these proceedings focus on the convergence of biomedical engineering topics ranging from formalized theory through experimental science and technological development to practical clinical applications.

Author : Carlos Mello
Publisher : BoD – Books on Demand
Page : 672 pages
File Size : 52,6 Mb
Release : 2009-10-01
Category : Medical
ISBN : 9789533070131

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Biomedical Engineering by Carlos Mello Pdf

Biomedical Engineering can be seen as a mix of Medicine, Engineering and Science. In fact, this is a natural connection, as the most complicated engineering masterpiece is the human body. And it is exactly to help our “body machine” that Biomedical Engineering has its niche. This book brings the state-of-the-art of some of the most important current research related to Biomedical Engineering. I am very honored to be editing such a valuable book, which has contributions of a selected group of researchers describing the best of their work. Through its 36 chapters, the reader will have access to works related to ECG, image processing, sensors, artificial intelligence, and several other exciting fields.