The Rise And Fall Of The Prostate Cancer Scam

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The Rise and Fall of the Prostate Cancer Scam

Author : Anthony H. Horan M. D.
Publisher : On the Write Path Publishing
Page : 188 pages
File Size : 43,6 Mb
Release : 2019-08-20
Category : Health & Fitness
ISBN : 1457570939

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The Rise and Fall of the Prostate Cancer Scam by Anthony H. Horan M. D. Pdf

"Dr. Horan's book, written with verve and passion, presents a compelling view of the prostate cancer The story over the last 30 years. The book articulates in a very clear fashion some of the missteps that took place following the embrace of PSA as a test for early detection of prostate cancer. He also points to a rational way forward, in an attempt to reduce the excessive reliance on systematic biopsies, and avoid over-diagnosis while identifying those patients with significant cancer who benefit from early detection. While experts may not agree with his views on some aspects of the data, his perspective is well informed and refreshing." Dr. Laurence Klotz, C.M. Professor of Surgery, University of Toronto Sunnybrook Chair of Prostate Cancer Research Chairman, World Urologic Oncology Federation Chairman, SIU Office of Research and uCARE Chairman, Canadian Urology Research Consortium In 1973, we urologists had prostate cancer about right, no screening, no radiation, and no radical surgery. All cancers discovered were assumed to be metastatic from the get-go. If any treatment was necessary, it was systemic hormone deprivation. But, ten years later (1983-1987) radical surgery was revived without new evidence; ultrasound probes were miniaturized to fit in the rectum; and the PSA blood test was described as capable of finding new cancers but as lacking the specificity required for screening. The whole world screened anyway. Money poured into U.S. hospitals and faculty practice plans. Post-radical surgery deaths (2600) peaked in 1992. By the autumn of 2011, two reports had showed that radical surgery did not lengthen cancer specific life compared to nothing. PSA screening was found by the Preventive Task Force of the U.S. Federal government to cause more harm than good. This book reinforces their statement. Anthony H. Horan, M.D., a graduate of Dartmouth College, received his medical degree from Columbia's College of Physicians and Surgeons. He did his internship in internal medicine and one year of general surgical residency at St. Luke's Hospital in New York. After two years in the Air Force as a general surgeon, Horan returned to New York for a Urology Residency at Columbia Presbyterian Hospital. After seven years of solo private practice in New York City with an appointment as instructor at the New York Medical College, he left to be Associate Professor of Surgery (Urology) at Marshall University in West Virginia. That was a VA based medical school. This led, eventually, to his appointment as Associate Clinical Professor of Urology, UCSF, at the Fresno VA hospital. There, he gathered and published the crucial data that led to this book. After becoming fully vested, he did an additional 14 years of solo private practice in Wyoming and California. He fully retired in the spring of 2018.

The Rise and Fall of the Prostate Cancer Scam

Author : Anthony H. Horan M. D.
Publisher : On the Write Path Publishing
Page : 188 pages
File Size : 44,5 Mb
Release : 2019-08-20
Category : Health & Fitness
ISBN : 1457570785

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The Rise and Fall of the Prostate Cancer Scam by Anthony H. Horan M. D. Pdf

"Dr. Horan's book, written with verve and passion, presents a compelling view of the prostate cancer The story over the last 30 years. The book articulates in a very clear fashion some of the missteps that took place following the embrace of PSA as a test for early detection of prostate cancer. He also points to a rational way forward, in an attempt to reduce the excessive reliance on systematic biopsies, and avoid over-diagnosis while identifying those patients with significant cancer who benefit from early detection. While experts may not agree with his views on some aspects of the data, his perspective is well informed and refreshing." Dr. Laurence Klotz, C.M. Professor of Surgery, University of Toronto Sunnybrook Chair of Prostate Cancer Research Chairman, World Urologic Oncology Federation Chairman, SIU Office of Research and uCARE Chairman, Canadian Urology Research Consortium In 1973, we urologists had prostate cancer about right, no screening, no radiation, and no radical surgery. All cancers discovered were assumed to be metastatic from the get-go. If any treatment was necessary, it was systemic hormone deprivation. But, ten years later (1983-1987) radical surgery was revived without new evidence; ultrasound probes were miniaturized to fit in the rectum; and the PSA blood test was described as capable of finding new cancers but as lacking the specificity required for screening. The whole world screened anyway. Money poured into U.S. hospitals and faculty practice plans. Post-radical surgery deaths (2600) peaked in 1992. By the autumn of 2011, two reports had showed that radical surgery did not lengthen cancer specific life compared to nothing. PSA screening was found by the Preventive Task Force of the U.S. Federal government to cause more harm than good. This book reinforces their statement. Anthony H. Horan, M.D., a graduate of Dartmouth College, received his medical degree from Columbia's College of Physicians and Surgeons. He did his internship in internal medicine and one year of general surgical residency at St. Luke's Hospital in New York. After two years in the Air Force as a general surgeon, Horan returned to New York for a Urology Residency at Columbia Presbyterian Hospital. After seven years of solo private practice in New York City with an appointment as instructor at the New York Medical College, he left to be Associate Professor of Surgery (Urology) at Marshall University in West Virginia. That was a VA based medical school. This led, eventually, to his appointment as Associate Clinical Professor of Urology, UCSF, at the Fresno VA hospital. There, he gathered and published the crucial data that led to this book. After becoming fully vested, he did an additional 14 years of solo private practice in Wyoming and California. He fully retired in the spring of 2018.

The Great Prostate Hoax

Author : Richard J. Ablin,Ronald Piana
Publisher : St. Martin's Press
Page : 272 pages
File Size : 40,7 Mb
Release : 2014-03-04
Category : Medical
ISBN : 9781137431318

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The Great Prostate Hoax by Richard J. Ablin,Ronald Piana Pdf

Every year, more than a million men undergo painful needle biopsies for prostate cancer, and upward of 100,000 have radical prostatectomies, resulting in incontinence and impotence. But the shocking fact is that most of these men would never have died from this common form of cancer, which frequently grows so slowly that it never even leaves the prostate. How did we get to a point where so many unnecessary tests and surgeries are being done? In The Great Prostate Hoax, Richard J. Ablin exposes how a discovery he made in 1970, the prostate-specific antigen (PSA), was co-opted by the pharmaceutical industry into a multibillion-dollar business. He shows how his discovery of PSA was never meant to be used for screening prostate cancer, and yet nonetheless the test was patented and eventurally approved by the FDA in 1994. Now, doctors and victims are beginning to speak out about the harm of the test, and beginning to search for a true prostate cancer-specific marker.

Invasion of the Prostate Snatchers

Author : Mark Scholz,Ralph Blum
Publisher : Other Press, LLC
Page : 305 pages
File Size : 41,7 Mb
Release : 2010-08-24
Category : Medical
ISBN : 9781590513859

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Invasion of the Prostate Snatchers by Mark Scholz,Ralph Blum Pdf

Every year almost a quarter of a million confused and frightened American men are tossed into a prostate cancer cauldron stirred by salespeople representing a multibillion-dollar industry. In this flourishing business, the radical prostatectomy is still the most widely recommended treatment option. Yet a recent and definitive study in the New England Journal of Medicine concluded that out of the fifty thousand prostate operations performed annually, more than forty thousand are unjustified. But this is no surprise given that 99 percent of all doctors treating this disease are surgeons or radiation therapists. The appalling fact is that men are still being rushed into a major operation that rarely prolongs life and more than half the time leaves them impotent. Invasion of the Prostate Snatchers is a report on the latest thinking in prostate cancer therapy: close monitoring–active surveillance rather than surgery or radiation–should be the initial treatment approach for many men. There are three stages of prostate cancer and this book will provide accurate information about how to distinguish between them: Low-Risk, which requires no immediate treatment; Intermediate-Risk, which will benefit from surgery, radiation, and/or hormonal therapy; and High-Risk, a type that does require immediate treatment with a combination of therapies. In a unique collaboration, doctor and patient provide a wholly new perspective on managing this disease. Ralph Blum’s account of his personal struggle, together with Dr.Mark Scholz’s presentation of newscientific advances, provides convincing evidence that this noninvasive approach can be crucial in preventing tens of thousands of men from being overtreated every year. Invasion of the Prostate Snatchers serves as an indispensable map through the medical minefield of prostate cancer.

Fast Facts: Prostate Cancer

Author : Roger S. Kirby,Manish I. Patel
Publisher : Karger Medical and Scientific Publishers
Page : 138 pages
File Size : 50,5 Mb
Release : 2017-03-08
Category : Medical
ISBN : 9781910797372

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Fast Facts: Prostate Cancer by Roger S. Kirby,Manish I. Patel Pdf

Prostate cancer is unusual among solid tumors in that the majority of affected men die with, rather than of, the disease. This presents many challenges to healthcare professionals and patients in terms of deciding if, when and how to intervene in order to control tumor growth and spread, thereby extending survival but without compromising quality of life. This is the ninth edition of 'Fast Facts: Prostate Cancer' since 1996, testament to the rapid changes in the field and the steadily improving outlook for patients. This new edition provides many key updates: • the Gleason grade grouping, which has valuable prognostic value • nomograms to evaluate risk • our rapidly expanding understanding of the genetics and underlying pathogenesis of prostate cancer and the development of genomic tests to help identify those at greatest risk of developing clinically significant disease • the continuing debate about the role of PSA in the screening, detection and monitoring of prostate cancer • advances in imaging techniques, particularly multiparametric MRI, which is improving the accuracy of biopsy and reducing the numbers of negative biopsies • the roles of drugs, surgery and radiotherapy in the treatment of prostate cancer at different stages, and our ever-improving understanding of when and how best to intervene, aided by improving understanding of the risk factors for disease progression. Primarily intended for primary care providers, specialist nurses, junior doctors and allied healthcare professionals, this highly readable resource provides a comprehensive overview of prostate cancer, enabling fully informed discussions with patients about this complex disease. Contents: • Epidemiology and pathophysiology • Diet, lifestyle and chemoprevention • Screening and early detection • Diagnosis, staging and prognostic indicators • Management of clinically localized disease • Managing recurrence after initial therapy • Management of metastatic prostate cancer • Management of castrate-resistant prostate cancer • Survivorship and treatment complications

Molecular Biology of Prostate Cancer

Author : Manfred Wirth,J. E. Altwein,B. Schmitz-Dräger,S. Kuptz
Publisher : Walter de Gruyter
Page : 220 pages
File Size : 48,9 Mb
Release : 2013-05-22
Category : Medical
ISBN : 9783110807271

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Molecular Biology of Prostate Cancer by Manfred Wirth,J. E. Altwein,B. Schmitz-Dräger,S. Kuptz Pdf

Adenocarcinoma of the Prostate

Author : Andrew W. Bruce,John Trachtenberg
Publisher : Springer Science & Business Media
Page : 225 pages
File Size : 44,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781447113980

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Adenocarcinoma of the Prostate by Andrew W. Bruce,John Trachtenberg Pdf

Carcinoma of the prostate increasingly dominates the attention of urologists for both scientific and clinical reasons. The search for an explanation and the prediction of the variable behaviour of the malignant prostatic cell continues unabated. The search for more precise tumour staging and more effective treatment is equally vigorous. Editors Andrew Bruce and John Trachtenberg have assembled acknowledged leaders in prostate cancer to present those areas of direct interest to the clinician. There are a number of other topics that might have been considered but most of these, such as experimental tumour models or biochemical factors affecting cell growth, still lack immediate application for the clinician. Carcinoma of the prostate continues to have its highest incidence in the western world, and the difference in comparison with the incidence in the Far East appears to be real and not masked by diagnostic or other factors. A number of other epidemiological aspects need careful analysis: Is the incidence increasing? Is the survival improving? Is the prognosis worse in the younger patient? Epidemiological data are easily misused and misinterpreted so that a precise analysis of the known facts makes an important opening chapter to this book.

Health Care Financing Review

Author : Anonim
Publisher : Unknown
Page : 476 pages
File Size : 51,7 Mb
Release : 2007
Category : Medical care
ISBN : RUTGERS:43008001299835

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Health Care Financing Review by Anonim Pdf

Testing Treatments

Author : Imogen Evans,Hazel Thornton,Iain Chalmers,Paul Glasziou
Publisher : Pinter & Martin Publishers
Page : 204 pages
File Size : 47,9 Mb
Release : 2011
Category : Health & Fitness
ISBN : 9781905177486

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Testing Treatments by Imogen Evans,Hazel Thornton,Iain Chalmers,Paul Glasziou Pdf

This work provides a thought-provoking account of how medical treatments can be tested with unbiased or 'fair' trials and explains how patients can work with doctors to achieve this vital goal. It spans the gamut of therapy from mastectomy to thalidomide and explores a vast range of case studies.

Radiation Oncology - A Question Based Review

Author : Borislav Hristov,Steven H. Lin,John P. Christodouleas
Publisher : Lippincott Williams & Wilkins
Page : 1331 pages
File Size : 40,7 Mb
Release : 2014-07-11
Category : Medical
ISBN : 9781469887920

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Radiation Oncology - A Question Based Review by Borislav Hristov,Steven H. Lin,John P. Christodouleas Pdf

Designed to serve as a comprehensive active learning tool for medical students, residents, and junior attending physicians, Radiation Oncology: A Question-Based Review is geared toward helping professionals quickly and efficiently review a specific topic in clinical radiation oncology. Organized into sections by system and with over 90 chapters covering all the sites and conditions for which radiation is used clinically. This publication covers in detail all the sites and cancer types currently treated with radiotherapy with an emphasis on treatment recommendations and the evidence behind them. Additionally, detailed questions are included on the natural history, epidemiology, diagnosis, staging, and treatment-related side effects for each cancer type.

Dr. Patrick Walsh's Guide to Surviving Prostate Cancer

Author : Patrick C. Walsh,Janet Farrar Worthington
Publisher : Balance
Page : 480 pages
File Size : 42,7 Mb
Release : 2018-05-15
Category : Health & Fitness
ISBN : 9781538763636

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Dr. Patrick Walsh's Guide to Surviving Prostate Cancer by Patrick C. Walsh,Janet Farrar Worthington Pdf

This guide covers every aspect of prostate cancer, from potential causes including diet to tests for diagnosis, curative treatment, and innovative means of controlling advanced stages of cancer.

The Key to Prostate Cancer

Author : Mark Scholz
Publisher : Unknown
Page : 492 pages
File Size : 51,6 Mb
Release : 2018-01-31
Category : Prostate
ISBN : 0999065211

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The Key to Prostate Cancer by Mark Scholz Pdf

A Guide to Personalized Care. With a self-administered quiz, Key directs readers to targeted information that is stage-specific. Written by 30 leading experts and edited by a prostate oncologist, Key is a welcome antidote for an industry dominated by surgeons.

Prostate Cancer Prevention

Author : Jack Cuzick,Mangesh A. Thorat
Publisher : Springer Science & Business Media
Page : 167 pages
File Size : 45,6 Mb
Release : 2014-02-15
Category : Medical
ISBN : 9783642451959

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Prostate Cancer Prevention by Jack Cuzick,Mangesh A. Thorat Pdf

Prostate cancer is by far the most common cancer in men and the second leading cause of death due to cancer. It comprises a mixed group of tumours displaying varying clinical behaviour: while some have a very aggressive course, others are rather indolent. Prevention of prostate cancer and discrimination between aggressive and indolent forms are important clinical goals and the acquisition of significant new evidence on means of achieving these aims makes this book particularly timely. A wide range of topics are covered by leading authorities in the field. The biology and natural history of prostate cancer are reviewed and the role of lifestyle and dietary factors, assessed. Detailed attention is paid to risk prediction biomarkers and to the role of novel high-throughput nucleic acid-based technologies in improving risk prediction and thereby allowing tailored approaches to cancer prevention. Potential means of chemoprevention of prostate cancer are also reviewed in depth, covering the very positive new data on the impact of aspirin as well as evidence regarding 5α-reductase inhibitors, DFMO and lycopene. Guidance is provided on the differentiation of aggressive from indolent disease and the policy and research implications of recent findings are examined. This book will be of interest to both clinicians and researchers.

Male Reproductive Cancers

Author : William D. Foulkes,Kathleen A. Cooney
Publisher : Springer Science & Business Media
Page : 346 pages
File Size : 55,6 Mb
Release : 2009-12-17
Category : Medical
ISBN : 9781441904492

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Male Reproductive Cancers by William D. Foulkes,Kathleen A. Cooney Pdf

Knowledge about cancer genetics is rapidly expanding, and has implications for all aspects of cancer research and treatment, including molecular causation, diagnosis, prevention, screening, and treatment. Additionally, while cancer genetics has traditionally focused on mutational events that have their primary effect within the cancer cell, recently the focus has widened, with evidence of the importance of epigenetic events and of cellular interactions in cancer development. The role of common genetic variation in determining the range of individual susceptibility within the population is increasingly recognized, and is now being widely addressed using information from the Human Genome Project. These new research directions will highlight determinants of cancer that lie outside the cancer cell, suggest new targets for intervention, and inform the design of strategies for prevention in groups at increased risk. Today, the NCI is putting more and more money into research into the genetics of cancer. The very first of the NCI’s stated research priorities is a project called The Cancer Genome Atlas. The Cancer Genome Atlas (TCGA) is a comprehensive and coordinated effort to accelerate the understanding of the molecular basis of cancer through the application of genome analysis technologies, including large-scale genome sequencing. The NCI and the NHGRI (National Human Genome Research Institute, where the series editor is employed) have each committed $50 million over three years to the TCGA Pilot Project. This book proposes cover the latest findings in the genetics of male reproductive cancers; specifically cancers of the prostate and testes. The volume will cover the epidemiology of these cancers; model systems, pathology, molecular genetics, and inherited susceptibility.