The Role Of Obesity In Cancer Survival And Recurrence

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The Role of Obesity in Cancer Survival and Recurrence

Institute of Medicine,Board on Health Care Services,National Cancer Policy Forum
The Role of Obesity in Cancer Survival and Recurrence Book PDF

Author : Institute of Medicine,Board on Health Care Services,National Cancer Policy Forum
Publisher : National Academies Press
Page : 126 pages
File Size : 40,8 Mb
Release : 2012-06-12
Category : Medical
ISBN : 9780309253369

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The Role of Obesity in Cancer Survival and Recurrence by Institute of Medicine,Board on Health Care Services,National Cancer Policy Forum Pdf

Recent research suggests that obesity and excess weight can play a prominent role in the incidence and progression of various cancers. Obesity results from an energy imbalance - that is, energy intake that is higher than energy expenditure - could also influence the growth of cancers. Recognizing the impact that current findings on obesity and cancer could have on future cancer prevention and care, the National Cancer policy Forum (NCPF) of the Institute of Medicine (IOM) help a 2-day workshop on "The Role of Obesity in Cancer Survival and Recurrence," in Washington, DC, on October 31 and November 1, 2011. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary reviews each presenter's latest clinical evidence on the obesity-cancer link and the molecular mechanisms that might explain that link. Clinicians, researchers, cancer survivors, and policy makers also discussed potential interventions to counter the effects of obesity on cancer, and research and policy measures needed to stem the rising tide of cancer mortality predicted by an increasingly overweight and older population worldwide. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary explores the complex web of molecular mechanisms that underlie the obesity-cancer link, the ways to design future studies to acquire the information needed to guide patient care, what to advise cancer patients about weight loss, diet, exercise, and other measures to reduce their risk of cancer progression or recurrence and policy suggestions related to research, education, and dissemination of the findings on obesity and cancer.

Physical Activity and Cancer

Kerry S. Courneya,Christine M. Friedenreich
Physical Activity and Cancer Book PDF

Author : Kerry S. Courneya,Christine M. Friedenreich
Publisher : Springer Science & Business Media
Page : 389 pages
File Size : 48,8 Mb
Release : 2010-11-26
Category : Medical
ISBN : 9783642042317

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Physical Activity and Cancer by Kerry S. Courneya,Christine M. Friedenreich Pdf

This book explores in depth the relation between physical activity and cancer control, including primary prevention, coping with treatments, recovery after treatments, long-term survivorship, secondary prevention, and survival. The first part of the book presents the most recent research on the impact of physical activity in preventing a range of cancers. In the second part, the association between physical activity and cancer survivorship is addressed. The effects of physical activity on supportive care endpoints (e.g., quality of life, fatigue, physical functioning) and disease endpoints (e.g., biomarkers, recurrence, survival) are carefully analyzed. In addition, the determinants of physical activity in cancer survivors are discussed, and behavior change strategies for increasing physical activity in cancer survivors are appraised. The final part of the book is devoted to special topics, including the relation of physical activity to pediatric cancer survivorship and to palliative cancer care.

Weight Control and Physical Activity

Harri Vainio,Franca Bianchini
Weight Control and Physical Activity Book PDF

Author : Harri Vainio,Franca Bianchini
Publisher : IARC
Page : 346 pages
File Size : 46,5 Mb
Release : 2002
Category : Health & Fitness
ISBN : 928323006X

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Weight Control and Physical Activity by Harri Vainio,Franca Bianchini Pdf

Avoiding overweight and obesity is the best-established diet-related risk factor for cancer. The proportion of people who are overweight/obese is increasing, and the amount of physical activity is decreasing in most populations, including urban populations in many developing countries. The increasing prevalence of overweight/obesity is presumably due to the increasing availability of highly palatable, high-energy foods, and an increasing sedentary lifestyle due to mechanisation of both workplace and leisure activities. Overweight/obesity and reduced physical activity increases the risk of cancers in various organs. Maintaining a healthy body weight and regular physical activity is the second most important way to prevent cancer, after tobacco control. The suggestions of possible public health actions to tackle these risk factors include the promotion of balanced diets, which are not excessive in energy, and broad education and planning to enable and encourage physical activity during work and leisure. Recommendations and a full discussion of these topics are included in the sixth volume in this series of Handbooks.

Breast Cancer Metastasis and Drug Resistance

Aamir Ahmad
Breast Cancer Metastasis and Drug Resistance Book PDF

Author : Aamir Ahmad
Publisher : Springer Nature
Page : 427 pages
File Size : 45,9 Mb
Release : 2019-08-27
Category : Medical
ISBN : 9783030203016

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Breast Cancer Metastasis and Drug Resistance by Aamir Ahmad Pdf

Resistance to therapies, both targeted and systemic, and metastases to distant organs are the underlying causes of breast cancer-associated mortality. The second edition of Breast Cancer Metastasis and Drug Resistance brings together some of the leading experts to comprehensively understand breast cancer: the factors that make it lethal, and current research and clinical progress. This volume covers the following core topics: basic understanding of breast cancer (statistics, epidemiology, racial disparity and heterogeneity), metastasis and drug resistance (bone metastasis, trastuzumab resistance, tamoxifen resistance and novel therapeutic targets, including non-coding RNAs, inflammatory cytokines, cancer stem cells, ubiquitin ligases, tumor microenvironment and signaling pathways such as TRAIL, JAK-STAT and mTOR) and recent developments in the field (epigenetic regulation, microRNAs-mediated regulation, novel therapies and the clinically relevant 3D models). Experts also discuss the advances in laboratory research along with their translational and clinical implications with an overarching goal to improve the diagnosis and prognosis, particularly that of breast cancer patients with advanced disease.

WHO Classification of Breast Tumours

WHO Classification of Tumours Editorial Board
WHO Classification of Breast Tumours Book PDF

Author : WHO Classification of Tumours Editorial Board
Publisher : International Agency for Research on Cancer
Page : 0 pages
File Size : 54,7 Mb
Release : 2019-11-21
Category : Medical
ISBN : 9283245008

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WHO Classification of Breast Tumours by WHO Classification of Tumours Editorial Board Pdf

Table of contents : - TNM staging of carcinomas of the breast - 1. Introduction to tumours of the breast - 2. Epithelial tumours of the breast - 3. Fibroepithelial tumours and hamartomas of the breast - 4. Tumours of the nipple - 5. Mesenchymal tumours of the breast - 6. Haematolymphoid tumours of the breast - 7. Tumours of the male breast - 8. Metastases to the breast - 9. Genetic tumours syndromes of the breast.

Management of Endometrial Cancer

Mansoor R. Mirza
Management of Endometrial Cancer Book PDF

Author : Mansoor R. Mirza
Publisher : Springer
Page : 324 pages
File Size : 42,9 Mb
Release : 2019-08-26
Category : Medical
ISBN : 9783319645131

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Management of Endometrial Cancer by Mansoor R. Mirza Pdf

This practical reference book provides up-to-date, evidence-based multidisciplinary guidelines on the epidemiology, biology, diagnosis, and treatment of endometrial cancer. Individual chapters focus on topics such as hormonal interactions, cancer prevention, genetic classification and its clinical applications. Recent advances in diagnostic methods are described. The treatment-oriented chapters include coverage of the roles of lymphadenectomy and sentinel node dissection, surgical complications, radiation techniques, and chemotherapy in early-stage disease. Treatment options in advanced disease, including hormonal therapy and targeted therapy, are considered separately, as is the management of rare tumor types. The authors are international key opinion leaders. Summaries of the ESMO/ESGO/ESTRO guidelines on management are included. Each clinical chapter ends with a summary of recommendations with the level of evidence.

Obesity and Cancer

Tobias Pischon,Katharina Nimptsch
Obesity and Cancer Book PDF

Author : Tobias Pischon,Katharina Nimptsch
Publisher : Springer
Page : 258 pages
File Size : 45,8 Mb
Release : 2016-12-01
Category : Medical
ISBN : 9783319425429

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Obesity and Cancer by Tobias Pischon,Katharina Nimptsch Pdf

This book provides a comprehensive and up-to-date review of the relationship between obesity and cancer. It opens with a global perspective on obesity and cancer incidence, followed by in-depth discussions of those cancers for which we have sufficient evidence of a causal relationship with obesity. It addresses topics such as the effects of obesity on cancer incidence and cancer survival, the effects of weight gain and weight loss in adulthood on cancer risk, the effects of childhood and adolescent obesity, and the role of body fat distribution in cancer risk. Individual chapters discuss potential pathways for the observed associations and explore possible mechanisms from both an epidemiological and an experimental perspective. It concludes with a population perspective on the cancer risk that is attributable to obesity and is thus potentially avoidable. This book is of particular value to researchers and epidemiologists and is also of interest to public health workers and clinicians.

Cancer and Energy Balance, Epidemiology and Overview

Nathan A. Berger
Cancer and Energy Balance Epidemiology and Overview Book PDF

Author : Nathan A. Berger
Publisher : Springer Science & Business Media
Page : 316 pages
File Size : 43,7 Mb
Release : 2010-06-16
Category : Medical
ISBN : 9781441955159

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Cancer and Energy Balance, Epidemiology and Overview by Nathan A. Berger Pdf

Energy Balance and Cancer, Epidemiology and Overview is the first in a series of monographs to address the multiple facets of the world wide pandemic of overweight and obesity and its relation to cancer. This volume, authored by leading experts in their perspective fields, provides a broad and comprehensive overview of the problem from the epidemiologic viewpoint with focus on both general and special populations as well as a description of potential molecular mechanisms and reviews of the latest studies of factors impacting the association of energy balance and cancer including the effects of genetics, caloric restriction, exercise, behavior and the built environment. The collected chapters and the authors contributing to this initial volume represent a transdisciplinary approach to analyze and develop novel approaches to understand and solve what, up to now, is a globally refractory problem. The book is written to be understandable and informative to individuals from all concerned disciplines. It should serve to orient students, investigators, nutritionists, public health officials, community planners, clinicians and policy makers to the extent of the problem, its multiple dimensions and potential approaches for research and corrective interventions.

Role of Obesity in Human Health and Disease

Venketeshwer Rao,Leticia Rao
Role of Obesity in Human Health and Disease Book PDF

Author : Venketeshwer Rao,Leticia Rao
Publisher : BoD – Books on Demand
Page : 209 pages
File Size : 55,7 Mb
Release : 2021-12-22
Category : Medical
ISBN : 9781839689796

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Role of Obesity in Human Health and Disease by Venketeshwer Rao,Leticia Rao Pdf

Many factors influence obesity including genetic, environmental, and lifestyle factors. Studies have shown obesity to be related to increased risk of human diseases. Despite efforts by health professionals to regulate obesity, its prevalence has increased globally in the past few decades. A better understanding of the causes of obesity and mechanisms by which obesity increases the risk of human diseases can lead to developing effective strategies that can save many lives worldwide. This book addresses some important aspects of the relationship between obesity and human health. Chapters cover such topics as body mass index, endocrine disorders, obesity, and endometrial cancer, the role of lifestyle factors in obesity, and much more.

Cognitive-Behavioral Treatment of Obesity

Zafra Cooper,Christopher G. Fairburn,Deborah M. Hawker
Cognitive Behavioral Treatment of Obesity Book PDF

Author : Zafra Cooper,Christopher G. Fairburn,Deborah M. Hawker
Publisher : Guilford Press
Page : 232 pages
File Size : 50,6 Mb
Release : 2004-09-07
Category : Psychology
ISBN : 1593850921

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Cognitive-Behavioral Treatment of Obesity by Zafra Cooper,Christopher G. Fairburn,Deborah M. Hawker Pdf

The first cognitive-behavioral treatment manual for obesity, this volume presents an innovative therapeutic model currently being evaluated in controlled research at Oxford University. From leading clinical researchers, the approach is specifically designed to overcome a major weakness of existing therapies: posttreatment weight regain. The book details powerful ways to help patients not only to achieve weight loss, but also to modify the problematic cognitions that undermine long-term weight control. Drawing on strategies proven effective with such problems as binge eating, the manual contains everything needed to implement the treatment: intervention guidelines, case examples, and reproducible handouts and forms.

From Cancer Patient to Cancer Survivor

National Research Council,Institute of Medicine,National Cancer Policy Board,Committee on Cancer Survivorship: Improving Care and Quality of Life
From Cancer Patient to Cancer Survivor Book PDF

Author : National Research Council,Institute of Medicine,National Cancer Policy Board,Committee on Cancer Survivorship: Improving Care and Quality of Life
Publisher : National Academies Press
Page : 0 pages
File Size : 40,6 Mb
Release : 2005-12-01
Category : Medical
ISBN : 0309095956

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From Cancer Patient to Cancer Survivor by National Research Council,Institute of Medicine,National Cancer Policy Board,Committee on Cancer Survivorship: Improving Care and Quality of Life Pdf

With the risk of more than one in three getting cancer during a lifetime, each of us is likely to experience cancer, or know someone who has survived cancer. Although some cancer survivors recover with a renewed sense of life and purpose, what has often been ignored is the toll taken by cancer and its treatmentâ€"on health, functioning, sense of security, and well-being. Long lasting effects of treatment may be apparent shortly after its completion or arise years later. The transition from active treatment to post-treatment care is critical to long-term health. From Cancer Patient to Cancer Survivor focuses on survivors of adult cancer during the phase of care that follows primary treatment. The book raises awareness of the medical, functional, and psychosocial consequences of cancer and its treatment. It defines quality health care for cancer survivors and identifies strategies to achieve it. The book also recommends improvements in the quality of life of cancer survivors through policies that ensure their access to psychosocial services, fair employment practices, and health insurance. This book will be of particular interest to cancer patients and their advocates, health care providers and their leadership, health insurers, employers, research sponsors, and the public and their elected representatives.

Pathophysiology - E-Book

Kathryn L. McCance,Sue E. Huether
Pathophysiology E Book Book PDF

Author : Kathryn L. McCance,Sue E. Huether
Publisher : Elsevier Health Sciences
Page : 1908 pages
File Size : 51,7 Mb
Release : 2013-12-18
Category : Medical
ISBN : 9780323293754

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Pathophysiology - E-Book by Kathryn L. McCance,Sue E. Huether Pdf

With easy-to-read, in-depth descriptions of disease, disease etiology, and disease processes, Pathophysiology: The Biologic Basis for Disease in Adults and Children, 7th Edition helps you understand the most important and the most complex pathophysiology concepts. More than 1,200 full-color illustrations and photographs make it easier to identify normal anatomy and physiology, as well as alterations of function. This edition includes a NEW Epigenetics and Disease chapter along with additional What’s New boxes highlighting the latest advances in pathophysiology. Written by well-known educators Kathryn McCance and Sue Huether, and joined by a team of expert contributors, this resource is the most comprehensive and authoritative pathophysiology text available! Over 1,200 full-color illustrations and photographs depict the clinical manifestations of disease and disease processes — more than in any other pathophysiology text. A fully updated glossary includes 1,000 terms, and makes lookup easier by grouping together similar topics and terms. Outstanding authors Kathryn McCance and Sue Huether have extensive backgrounds as researchers and instructors, and utilize expert contributors, consultants, and reviewers in developing this edition. Chapter summary reviews provide concise synopses of the main points of each chapter. Consistent presentation of diseases includes pathophysiology, clinical manifestations, and evaluation and treatment. Lifespan content includes ten separate pediatric chapters and special sections with aging and pediatrics content. Algorithms and flowcharts of diseases and disorders make it easy to follow the sequential progression of disease processes. Nutrition and Disease boxes explain the link between concepts of health promotion and disease. Updated content on leukocytes in pain modulation, seizure disorders, brain injuries and disorders, acute encephalopathies, reproductive disorders, and much more keep you at the cutting edge of this constantly changing field. What’s New? boxes highlight the most current research and findings to ensure you have the most up-to-date information. New animations, review questions, Key Points, and an audio glossary have been added to the Evolve companion website to strengthen your understanding of key concepts. Media Resources Lists encourage you to develop a study plan to master the important content in each chapter.

Pathophysiology

Kathryn L. McCance, RN, PhD,Sue E. Huether, RN, PhD
Pathophysiology Book PDF

Author : Kathryn L. McCance, RN, PhD,Sue E. Huether, RN, PhD
Publisher : Elsevier Health Sciences
Page : 1908 pages
File Size : 51,6 Mb
Release : 2014-01-14
Category : Medical
ISBN : 9780323088541

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Pathophysiology by Kathryn L. McCance, RN, PhD,Sue E. Huether, RN, PhD Pdf

With easy-to-read, in-depth descriptions of disease, disease etiology, and disease processes, Pathophysiology: The Biologic Basis for Disease in Adults and Children, 7th Edition helps you understand the most important and the most complex pathophysiology concepts. More than 1,200 full-color illustrations and photographs make it easier to identify normal anatomy and physiology, as well as alterations of function. This edition includes a NEW Epigenetics and Disease chapter along with additional What's New boxes highlighting the latest advances in pathophysiology. Written by well-known educators Kathryn McCance and Sue Huether, and joined by a team of expert contributors, this resource is the most comprehensive and authoritative pathophysiology text available! Over 1,200 full-color illustrations and photographs depict the clinical manifestations of disease and disease processes - more than in any other pathophysiology text. A fully updated glossary includes 1,000 terms, and makes lookup easier by grouping together similar topics and terms. Outstanding authors Kathryn McCance and Sue Huether have extensive backgrounds as researchers and instructors, and utilize expert contributors, consultants, and reviewers in developing this edition. Chapter summary reviews provide concise synopses of the main points of each chapter. Consistent presentation of diseases includes pathophysiology, clinical manifestations, and evaluation and treatment. Lifespan content includes ten separate pediatric chapters and special sections with aging and pediatrics content. Algorithms and flowcharts of diseases and disorders make it easy to follow the sequential progression of disease processes. Nutrition and Disease boxes explain the link between concepts of health promotion and disease. EXTENSIVELY Updated content reflects advances in pathophysiology including tumor biology invasion and metastases, the epidemiology of cancer, diabetes mellitus, insulin resistance, thyroid and adrenal gland disorders, female reproductive disorders including benign breast diseases and breast cancer, and a separate chapter on male reproductive disorders and cancer. NEW! Chapter on epigenetics and disease. Additional What's New boxes highlight the most current research and clinical development.

Lost in Translation

Rakesh Srivastava,Wojciech Maksymowicz,Wlodek Lopaczynski
Lost in Translation Book PDF

Author : Rakesh Srivastava,Wojciech Maksymowicz,Wlodek Lopaczynski
Publisher : World Scientific
Page : 768 pages
File Size : 47,7 Mb
Release : 2014-03-14
Category : Medical
ISBN : 9789814489089

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Lost in Translation by Rakesh Srivastava,Wojciech Maksymowicz,Wlodek Lopaczynski Pdf

This book is all about the definition and finding ways to prioritize and accelerate translation research in biomedical sciences and rapidly turning new knowledge into first-in-human studies. It represents an effort to bring together scientists active in various areas of translational research to share science and, hopefully, generate new ideas and potential collaborations. The book provides a comprehensive overview of translational work that includes significant discoveries and pioneering contributions, e.g., in immunology, gene therapy, stem cells and population sciences. It may be used as an advanced textbook by graduate students and even ambitious undergraduates in biomedical sciences. It is also suitable for non-experts, i.e. medical doctors, who wish to have an overview of some of the fundamental models in translational research. Managing the translational enterprise remains a work in progress. The world is changing rapidly, and the scientific world needs to seek new ways to ensure that discoveries get translated for patients efficiently and as quickly as possible. In addition, everyone expects the investment in biomedical research should pay dividends through effective therapeutic solutions. This unique project provides a broad collaborative approach of the international scientific team to present its view and opinion how to cross barriers to incentives for translational research in medical sciences. Contributing to the book is an international team of prominent co-authors. The book consists of unique and widely treated topics, and includes new hypotheses, data and analyses. Contents:Barriers to Incentives for Translational ResearchIntegrating Emerging Science into Clinical PracticeOrganization, Prioritization, Review and Funding for the Translational ResearchTranslational Sciences in Cancer ResearchTranslational Science in Infectious DiseasesTranslation Research in Endocrinology and NutritionTranslation Research and NeuroscienceStem Cells and Translation ResearchThe Role of Translational Research in Public Health and Behavioral SciencesTranslational Epidemiology, Biostatistics and InformaticsTranslational Research Outcomes and Resources Readership: Graduate students and researchers in cancer research, pharmacology/drug discovery/pharmaceuticals, immunology, infectious diseases and public health. Keywords:Translational Research;Basic and Clinical Sciences;Prevention;Population SciencesKey Features:International team of prominent co-authorsUnique and widely treated topicsNew hypotheses, data and analyses

Lost in Translation

Rakesh K. Srivastava
Lost in Translation Book PDF

Author : Rakesh K. Srivastava
Publisher : World Scientific
Page : 766 pages
File Size : 49,9 Mb
Release : 2014
Category : Medical
ISBN : 9789814489072

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Lost in Translation by Rakesh K. Srivastava Pdf

This book is all about the definition and finding ways to prioritize and accelerate translation research in biomedical sciences and rapidly turning new knowledge into first-in-human studies. It represents an effort to bring together scientists active in various areas of translational research to share science and, hopefully, generate new ideas and potential collaborations. The book provides a comprehensive overview of translational work that includes significant discoveries and pioneering contributions, e.g., in immunology, gene therapy, stem cells and population sciences. It may be used as an advanced textbook by graduate students and even ambitious undergraduates in biomedical sciences. It is also suitable for non-experts, i.e. medical doctors, who wish to have an overview of some of the fundamental models in translational research. Managing the translational enterprise remains a work in progress. The world is changing rapidly, and the scientific world needs to seek new ways to ensure that discoveries get translated for patients efficiently and as quickly as possible. In addition, everyone expects the investment in biomedical research should pay dividends through effective therapeutic solutions. This unique project provides a broad collaborative approach of the international scientific team to present its view and opinion how to cross barriers to incentives for translational research in medical sciences. Contributing to the book is an international team of prominent co-authors. The book consists of unique and widely treated topics, and includes new hypotheses, data and analyses. Sample Chapter(s). Foreword (41 KB). Chapter 1: Translational Research: Lost in Complexity (305 KB). Contents: Barriers to Incentives for Translational Research; Integrating Emerging Science into Clinical Practice; Organization, Prioritization, Review and Funding for the Translational Research; Translational Sciences in Cancer Research; Translational Science in Infectious Diseases; Translation Research in Endocrinology and Nutrition; Translation Research and Neuroscience; Stem Cells and Translation Research; The Role of Translational Research in Public Health and Behavioral Sciences; Translational Epidemiology, Biostatistics and Informatics; Translational Research Outcomes and Resources. Readership: Graduate students and researchers in cancer research, pharmacology/drug discovery/pharmaceuticals, immunology, infectious diseases and public health.