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Author : Marco António Campinho,Laurent M. Sachs
Publisher : Frontiers Media SA
Page : 213 pages
File Size : 54,8 Mb
Release : 2020-01-24
Category : Electronic
ISBN : 9782889634033
Author : Marco António Campinho,Laurent M. Sachs
Publisher : Frontiers Media SA
Page : 155 pages
File Size : 42,8 Mb
Release : 2024-04-26
Category : Medical
ISBN : 9782832548455
Thyroid hormones role in development was first suggested in the 18th century when a relationship between goiter and cretinism was found by F.E. Fodere. But it was Rudolf Virchow work in the late 19th century with thyroidectomized animals that clearly demonstrated that goiter led to cretinism. This opened the door to the understanding of TH action on vertebrate development. However given the relative ease by which cretinism could be treated simply by eating animal thyroid gland or iodine supplementation, research into the action of TH on vertebrate development has been lagging. This was further enhanced by the complex biology of TH where, after production in the gland, entry, activation and binding of the TH to cognate receptors in target cells is highly regulated. Nonetheless, new scientific advances and technologies are now providing tools to dissect the developmental role of TH on vertebrate development, both embryonic and post-natal. The post-natal role of TH in vertebrate development is long known from anuran studies but less evidences exist from other vertebrates. Recently, new evidences show that TH constitute key developmental signal in embryonic development of vertebrates, especially in neural development, from humans to fish. This new evidences are corroborating long-standing observations that infants from mothers with impaired TH physiology presented changes in mental and cognitive indexes. Nonetheless, given that TH constitute integrative physiological signals in vertebrates a new scenario is emerging whereas TH seem to be important in the development and maturation of most organ systems in vertebrates during their different life transitions
Author : Martin Schreibman,Colin G. Scanes,Peter K.T. Pang
Publisher : Academic Press
Page : 620 pages
File Size : 51,7 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780323144407
The Endocrinology of Growth, Development, and Metabolism in Vertebrates provides an overview of vertebrate endocrinology. This book aims to strengthen the bridge between medical and comparative endocrinologists by addressing the benefits that they can derive from this association. Organized into five parts encompassing 24 chapters, this volume starts with a discussion on the structure and biological function of growth hormone (GH) and prolactin (PRL) family. This book then explains the extrinsic, genetic, and humoral factors that influence animal growth, particularly in poikilotherms. This text also elaborates the environmental conditions that affect the growth of poikilotherms, including food availability, temperature, and photoperiod. Other chapters discuss how somatotropin affects the growth development in homeotherms, such as livestock species. The reader is also introduced to the metabolic actions of GH, which can be described in terms of short-lived insulin-like effects. Endocrinologists, molecular endocrinologists, biologists, molecular biologists, biochemists, researchers, and physicians will find this book extremely useful.
Author : David O. Norris,Kristin H. Lopez
Publisher : Academic Press
Page : 1681 pages
File Size : 55,7 Mb
Release : 2010-11-25
Category : Technology & Engineering
ISBN : 9780080958095
This series of volumes represents a comprehensive and integrated treatment of reproduction in vertebrates from fishes of all sorts through mammals. It is designed to provide a readable, coordinated description of reproductive basics in each group of vertebrates as well as an introduction to the latest trends in reproductive research and our understanding of reproductive events. Whereas each chapter and each volume is intended to stand alone as a review of that topic or vertebrate group, respectively, the volumes are prepared so as to provide a thorough topical treatment across the vertebrates. Terminology has been standardized across the volumes to reduce confusion where multiple names exist in the literature, and a comprehensive glossary of these terms and their alternative names is provided. A complete, essential and up to date reference for research scientists working on vertebrate hormones and reproduction - and on animlals as models in human reproductive research Covers the endocrinology, neuroendocrinology, physiology, behaviour and anatomy of vertebrate reproduction Structured coverage of the major themes for all five vertebrate groups allows a consistent treatment for all Special chapters elaborate on features specific to individual vertebrate groups and to comparative aspects, similarities and differences between them
Author : Ernest James William Barrington
Publisher : Unknown
Page : 552 pages
File Size : 45,5 Mb
Release : 1979
Category : Medical
ISBN : UOM:39015003784355
Author : David Norris,Kristin Lopez
Publisher : Academic Press
Page : 297 pages
File Size : 49,9 Mb
Release : 2011-05-04
Category : Technology & Engineering
ISBN : 9780080962290
This series of volumes represents a comprehensive and integrated treatment of reproduction in vertebrates from fishes of all sorts through mammals. It is designed to provide a readable, coordinated description of reproductive basics in each group of vertebrates as well as an introduction to the latest trends in reproductive research and our understanding of reproductive events. Whereas each chapter and each volume is intended to stand alone as a review of that topic or vertebrate group, respectively, the volumes are prepared so as to provide a thorough topical treatment across the vertebrates. Terminology has been standardized across the volumes to reduce confusion where multiple names exist in the literature, and a comprehensive glossary of these terms and their alternative names is provided. A complete, essential and up to date reference for research scientists working on vertebrate hormones and reproduction - and on animlals as models in human reproductive research Covers the endocrinology, neuroendocrinology, physiology, behaviour and anatomy of vertebrate reproduction Structured coverage of the major themes for all five vertebrate groups allows a consistent treatment for all Special chapters elaborate on features specific to individual vertebrate groups and to comparative aspects, similarities and differences between them
Author : Ernest James William Barrington
Publisher : Unknown
Page : 174 pages
File Size : 40,5 Mb
Release : 1964
Category : Evolution
ISBN : UOM:39015003195768
Author : David Norris,James A. Carr
Publisher : Academic Press
Page : 599 pages
File Size : 43,9 Mb
Release : 2013-05-04
Category : Science
ISBN : 9780123964656
Vertebrate Endocrinology represents more than just a treatment of the endocrine system-it integrates hormones with other chemical bioregulatory agents not classically included with the endocrine system. It provides a complete overview of the endocrine system of vertebrates by first emphasizing the mammalian system as the basis of most terminology and understanding of endocrine mechanisms and then applies that to non-mammals. The serious reader will gain both an understanding of the intricate relationships among all of the body systems and their regulation by hormones and other bioregulators, but also a sense of their development through evolutionary time as well as the roles of hormones at different stages of an animal's life cycle. Includes new full color format includes over 450 full color, completely redrawn image Features a companion web site hosting all images from the book as PPT slides and .jpeg files Presents completedly updated and revitalized content with new chapters, such as Endocrine Disrupters and Behavioral Endocrinology Offers new clinical correlation vignettes throughout
Author : Zerina Johanson,Charlie Underwood,Martha Richter
Publisher : Cambridge University Press
Page : 283 pages
File Size : 46,9 Mb
Release : 2019-01-10
Category : Nature
ISBN : 9781107179448
World-class palaeontologists and biologists summarise the state-of-the-art on fish evolution and development.
Author : Brian K. Follett,Susumu Ishii,Asha Chandola
Publisher : Springer
Page : 354 pages
File Size : 53,5 Mb
Release : 1985
Category : Medical
ISBN : UOM:39015010042201
Results of 1970 questionnaire examining the occupational preferences of northern high school students. preferences were determined by school rather than ethnic group.
Author : David O. Norris
Publisher : Elsevier
Page : 573 pages
File Size : 54,7 Mb
Release : 2006-11-27
Category : Technology & Engineering
ISBN : 9780080466392
One of the only books to discuss all vertebrates, the fourth edition of Vertebrate Endocrinology has been completely reorganized and updated to explore the intricate mechanisms that control human physiology and behavior as well as that of other vertebrate animals. Perfect for students in endocrinology, zoology, biology and physiology, it allows readers to gain both an understanding of the intricate relationships among all of the body systems and their regulation by hormones and other bioregulators, but also a sense of their development through evolutionary time as well as the roles of hormones at different stages of an animal’s life cycle. Chapters have been reorganized to more closely follow traditional classroom presentation and extensive suggested readings are included at the end of each chapter allowing the reader to obtain further information as well as connect concepts to the literature on which the book is based. For the first time, this edition features four-color illustrations. Provides a complete overview of the endocrine system of vertebrates by first emphasizing the mammalian system as the basis of most terminology and understanding of endocrine mechanisms and then applies that to non-mammals Introduces the reader to suitable concepts and explanation of jargon so that the reader will be able to delve directly into the primary literature on any endocrine-related topic with a background that will aid in their interpretation of new information Revised and updated chapter on The Molecular Bases for Chemical Regulation that now includes more evolutionary data Includes information on endocrine disrupting chemicals and their implications on the health of wildlife and humans
Author : Reiko Kishi,Philippe Grandjean
Publisher : Springer Nature
Page : 554 pages
File Size : 53,9 Mb
Release : 2019-12-13
Category : Medical
ISBN : 9789811505201
This book provides concise and cutting-edge studies on threats resulting from exposure to environmental chemicals that can affect human health and development, with a particular emphasis on the DOHaD concept. The book is divided into five main parts, the first of which includes an introduction to the impacts of developmental exposure to environmental chemicals and historical perspectives, while the second focuses on how environmental chemicals can affect human organs, including neurodevelopment, immune functions, etc. In turn, the third part addresses the characteristics of specific chemicals and their effects on human health and development, while the fourth part provides a basis for future studies by highlighting the latest innovations in toxicology, remaining challenges, and promising strategies in children’s environmental health research, as well as ideas on how to bridge the gap between research evidence and practical policymaking. The fifth and last part outlines further research directions and related policymaking aspects. Health Impacts of Developmental Exposure to Environmental Chemicals will appeal to young and veteran researchers, students, and physicians (especially gynecologists and pediatricians) who are seeking comprehensive information on how children’s health can be affected by harmful chemicals and other environmental toxicants.
Author : F. Delange,D.A. Fisher,D. Glinoer
Publisher : Springer Science & Business Media
Page : 360 pages
File Size : 41,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781468475807
Systematic screening for congenital hypothyroidism in the newborn was introduced some 15 years ago. The main objective was the prevention of mental retardation due to thyroid hormone deficiency during the early months of life. During the past decade screening programs have become routine throughout most of the industrialized world and many questions relating to implementation, organization and quality control of such programs have been largely resolved. Preliminary IQ and neurological data have indicated that screening and early treatment do, in fact, prevent mental retardation. However, a number of scientific questions related to congenital hypothyroidism remain unanswered and extensive research activities are ongoing in the field. The objective of the organizers of the Brussels workshop was to focus almost exclusively on these current research aspects of the screening programs. This workshop is the third international conference specifically devoted to neonatal thyroid screening. The first was held in La Malbaie in Quebec in the fall of 1979. That meeting was well organized and highly productive. Its proceedings constitute a bible in the field. After the Quebec meeting, we witnessed major and rapid advances in our understanding of neonatal thyroid physiology as well as screening methodology, organiza tion, data management, the significance of an approach to false negative and false positive results,patient follow-up, and assessment of follow-up and treatment, and the psychoneurological evaluation of affected infants. Some of these aspects were further developed during a second highly pro ductive international conference organized in Tokyo in 1982.
Author : Victor R. Preedy,Gerard N. Burrow,Ronald Ross Watson
Publisher : Academic Press
Page : 1334 pages
File Size : 40,7 Mb
Release : 2009-03-17
Category : Technology & Engineering
ISBN : 0080920861
Over two billion people worldwide are at risk for the spectrum of disorders known as "The Iodine Deficiency Disorders." 1-10% will suffer cretinism; 5-30% will have some sort of brain damage or neurological impairment and 30-70% will be hypothyroid. The causes of iodine deficiencies can be considered from both simplistic and more complex perspectives: From the leaching of iodine from soil resulting in crops with low iodine content to malnutrition resulting in impaired iodine absorption. Poor dietary diversification and impoverished socio-economic development can also lead to iodine deficiencies. Although it is possible to diagnose and treat deficiencies, there is still an ongoing dialogue regarding the detailed molecular pathology of iodine homeostatis, how hypothyroidism impacts the body tissues, and efficient diagnosis and treatment of the Iodine Deficiency Disorders. This Handbook provides a resource of information on the various pathways and processes based on different countries or diseases. Because there is a constant flow of new information on iodine and related disorders, the goal of this Handbook is to provide a base of scientific information upon which additional knowledge can be applied. Provides important information on one of the most common micro-nutrient deficiencies in the world, the most important "single nutrient-multiple consequences" paradigm today Includes information on iodine-related diseases, including those that are common, preventable and treatable Provides insight from a broad perspective of viewpoints -- from subcellular transports to economic impact
Author : OECD
Publisher : OECD Publishing
Page : 33 pages
File Size : 46,7 Mb
Release : 2009-09-08
Category : Electronic
ISBN : 9789264076242
This Test Guideline describes an amphibian metamorphosis assay intended to screen substances which may interfere with the normal functioning of the hypothalamo-pituitary-thyroid axis. The assay was validated with the species Xenopus laevis, which is ...
