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Author : Richard P. Huemer
Publisher : Unknown
Page : 289 pages
File Size : 42,8 Mb
Release : 1986
Category : Molecular biology
ISBN : 0716717611
Author : Giovanni Boniolo,Marco J. Nathan
Publisher : Taylor & Francis
Page : 288 pages
File Size : 46,6 Mb
Release : 2016-11-18
Category : Philosophy
ISBN : 9781317378358
Philosophy of Molecular Medicine: Foundational Issues in Theory and Practice aims at a systematic investigation of a number of foundational issues in the field of molecular medicine. The volume is organized around four broad modules focusing, respectively, on the following key aspects: What are the nature, scope, and limits of molecular medicine? How does it provide explanations? How does it represent and model phenomena of interest? How does it infer new knowledge from data and experiments? The essays collected here, authored by prominent scientists and philosophers of science, focus on a handful of mainstream topics in the philosophical literature, such as causation, explanation, modeling, and scientific inference. These previously unpublished contributions shed new light on these traditional topics by integrating them with problems, methods, and results from three prominent areas of contemporary biomedical science: basic research, translational and clinical research, and clinical practice.
Author : R.J. Trent
Publisher : Academic Press
Page : 348 pages
File Size : 42,6 Mb
Release : 2012-08-17
Category : Medical
ISBN : 9780123814517
Molecular Medicine is the application of genetic or DNA-based knowledge to the modern practice of medicine. Molecular Medicine, 4e, provides contemporary insights into how the genetic revolution is influencing medical thinking and practice. The new edition includes recent changes in personalized medicine, new growth in omics and direct-to-consumer DNA testing, while focusing on advances in the Human Genome project and implications of the advances in clinical medicine. Graduate students, researchers, clinicians and allied health professionals will appreciate the background history and clinical application of up-to-date molecular advances. Extensively revised to incorporate the results of the Human Genome Project, it provides the latest developments in molecular medicine The only book in Molecular Medicine to reach its fourth edition Identifies current practice as well as future developments Presents extensive tables, well presented figures and resources for further understanding
Author : Giovanni Boniolo,Marco J. Nathan
Publisher : Routledge
Page : 0 pages
File Size : 54,9 Mb
Release : 2017
Category : Medicine
ISBN : 1138940674
Cover -- Half-Title -- Title -- Copyright -- Contents -- List of Contributors -- Introduction -- Part I: Nature, Origins, and Scope -- 1 Molecular Medicine: The Clinical Method Enters the Lab -- 2 Personalized Medicine: Historical Roots of a Medical Model -- 3 From the Concept of Genetic Disease to the Geneticization of Diseases: Analyzing and Solving the Paradox of Contemporary Medical Genetics -- Part II: Explanation -- 4 Molecular Complexity: Why Has Psychiatry Not Been Revolutionized by Genomics (Yet)? -- 5 How Cancer Spreads: Reconceptualizing a Disease
Author : Marschall S. Runge,Cam Patterson
Publisher : Springer Science & Business Media
Page : 1299 pages
File Size : 46,5 Mb
Release : 2007-11-18
Category : Medical
ISBN : 9781592599639
The concept of molecular medicine dates back to Linus means that there are many new opportunities and challenges Pauling, who in the late 1940s and early 1950s generalized for clinical medicine. One of the effects of the completion of from the ideas that came from the study of the sickle cell the Human Genome Project is the increasing application of hemoglobin molecule. With the first cloning of human genes the fields of molecular biology and genetics to the und- about 1976, molecular genetics took the molecular perspec- standing and management of common diseases. Assimi- tive on disease to the level of DNA. The term molecular tion of the new developments since the first edition has been medicine achieved wide currency in the 1980s with the ably accomplished by Drs. Runge and Patterson with the assignment of this designation to journals, at least one soci- help of their many knowledgeable authors. ety, institutes, and academic divisions of departments of in- As was evident in the first edition, molecular genetics is ternal medicine. Undoubtedly, molecular medicine has been involved in every specialty of medicine. A recurrent theme abetted by the Human Genome Project, which has aided in that edition, perhaps even more striking in the present one, greatly in the molecular characterization of disease.
Author : Michel Morange
Publisher : Harvard University Press
Page : 350 pages
File Size : 47,7 Mb
Release : 2000
Category : History
ISBN : 0674001699
Every day it seems the media focus on yet another new development in biology--gene therapy, the human genome project, the creation of new varieties of animals and plants through genetic engineering. These possibilities have all emanated from molecular biology. A History of Molecular Biology is a complete but compact account for a general readership of the history of this revolution. Michel Morange, himself a molecular biologist, takes us from the turn-of-the-century convergence of molecular biology's two progenitors, genetics and biochemistry, to the perfection of gene splicing and cloning techniques in the 1980s. Drawing on the important work of American, English, and French historians of science, Morange describes the major discoveries--the double helix, messenger RNA, oncogenes, DNA polymerase--but also explains how and why these breakthroughs took place. The book is enlivened by mini-biographies of the founders of molecular biology: Delbrück, Watson and Crick, Monod and Jacob, Nirenberg. This ambitious history covers the story of the transformation of biology over the last one hundred years; the transformation of disciplines: biochemistry, genetics, embryology, and evolutionary biology; and, finally, the emergence of the biotechnology industry. An important contribution to the history of science, A History of Molecular Biology will also be valued by general readers for its clear explanations of the theory and practice of molecular biology today. Molecular biologists themselves will find Morange's historical perspective critical to an understanding of what is at stake in current biological research.
Author : Thomas F. Kresina
Publisher : John Wiley & Sons
Page : 408 pages
File Size : 53,8 Mb
Release : 2004-03-24
Category : Science
ISBN : 9780471461043
An Introduction to Molecular Medicine and Gene Therapy Edited by Thomas F. Kresina, Ph.D. Gene therapy, or the use of genetic manipulation for disease treatment, is derived from advances in genetics, molecular biology, clinical medicine, and human genomics. Molecular medicine, the application of molecular biological techniques to disease treatment and diagnosis, is derived from the development of human organ transplantation, pharmacotherapy, and elucidation of the human genome. An Introduction to Molecular Medicine and Gene Therapy provides a basis for interpreting new clinical and basic research findings in the areas of cloning, gene transfer, and targeting; the applications of genetic medicine to clinical conditions; ethics and governmental regulations; and the burgeoning fields of genomics, biotechnology, and bioinformatics. By dividing the material into three sections - an introduction to basic science, a review of clinical applications, and a discussion of the evolving issues related to gene therapy and molecular medicine-this comprehensive manual describes the basic approaches to the broad range of actual and potential genetic-based therapies. In addition, An Introduction to Molecular Medicine and Gene Therapy: * Covers new frontiers in gene therapy, animal models, vectors, gene targeting, and ethical/legal considerations * Provides organ-based reviews of current studies in gene therapy for monogenetic, multifactoral or polygenic disorders, and infectious diseases * Includes bold-faced terms, key concepts, summaries, and lists of helpful references by subject in each chapter * Contains appendices on commercial implications and a review of the history of gene therapy This textbook offers a clear, concise writing style, drawing upon the expertise of the authors, all renowned researchers in their respective specialties of molecular medicine. Researchers in genetics and molecular medicine will all find An Introduction to Molecular Medicine and Gene Therapy to be an essential guide to the rapidly evolving field of gene therapy and its applications in molecular medicine.
Author : Dennis W. Ross
Publisher : Unknown
Page : 172 pages
File Size : 48,6 Mb
Release : 2014-01-15
Category : Electronic
ISBN : 1468495747
Author : Jens Kurreck,Cy Aaron Stein
Publisher : John Wiley & Sons
Page : 419 pages
File Size : 45,6 Mb
Release : 2016-02-16
Category : Science
ISBN : 9783527331895
Easy to read, yet comprehensive, this is the perfect introduction into the molecular basis of disease and the novel treatment options that have become available. The authors, Jens Kurreck and Cy Stein, have both long-standing teaching experience on the subject, one from a biologist's angle, the other with a medical background. Together, they have produced a modern textbook for courses in Molecular Medicine that incorporates modules from immunology to signaling, from virology to gene therapy, and the latest development in personalized medicine.
Author : R.J. Trent
Publisher : Academic Press
Page : 347 pages
File Size : 49,6 Mb
Release : 2012-08-22
Category : Science
ISBN : 9780123814524
Molecular Medicine is the application of genetic or DNA-based knowledge to the modern practice of medicine. Molecular Medicine, 4e, provides contemporary insights into how the genetic revolution is influencing medical thinking and practice. The new edition includes recent changes in personalized medicine, new growth in omics and direct-to-consumer DNA testing, while focusing on advances in the Human Genome project and implications of the advances in clinical medicine. Graduate students, researchers, clinicians and allied health professionals will appreciate the background history and clinical application of up-to-date molecular advances. Extensively revised to incorporate the results of the Human Genome Project, it provides the latest developments in molecular medicine The only book in Molecular Medicine to reach its fourth edition Identifies current practice as well as future developments Presents extensive tables, well presented figures and resources for further understanding
Author : William R. Clark
Publisher : Oxford University Press
Page : 256 pages
File Size : 46,9 Mb
Release : 1999-04-22
Category : Medical
ISBN : 9780195130843
This popular exploration of gene therapy presents the underlying molecular biology in readily accessible form, and lays out the early efforts and future prospects for gene therapy to revolutionize the treatment of human genetic diseases.
Author : Dhavendra Kumar
Publisher : Academic Press
Page : 607 pages
File Size : 54,8 Mb
Release : 2019-11-30
Category : Science
ISBN : 9780128094426
Clinical Molecular Medicine: Principles and Practice presents the latest scientific advances in molecular and cellular biology, including the development of new and effective drug and biological therapies and diagnostic methods. The book provides medical and biomedical students and researchers with a clear and clinically relevant understanding on the molecular basis of human disease. With an increased focus on new practice concepts, such as stratified, personalized and precision medicine, this book is a valuable and much-needed resource that unites the core principles of molecular biology with the latest and most promising genomic advances. Illustrates the fundamental principles and therapeutic applications of molecular and cellular biology Offers a clinically focused account of molecular heterogeneity Includes comprehensive coverage of many different disorders, including growth and development, cardiovascular, metabolic, skin, blood, digestive, inflammatory, neuropsychiatric disorders, and many more
Author : Wiley
Publisher : Wiley-Interscience
Page : 794 pages
File Size : 54,5 Mb
Release : 2001-11-01
Category : Science
ISBN : 0471374970
Author : Robin Wolfe Scheffler
Publisher : University of Chicago Press
Page : 391 pages
File Size : 40,9 Mb
Release : 2019-06-15
Category : Medical
ISBN : 9780226628370
Is cancer a contagious disease? In the late nineteenth century this idea, and attending efforts to identify a cancer “germ,” inspired fear and ignited controversy. Yet speculation that cancer might be contagious also contained a kernel of hope that the strategies used against infectious diseases, especially vaccination, might be able to subdue this dread disease. Today, nearly one in six cancers are thought to have an infectious cause, but the path to that understanding was twisting and turbulent. A Contagious Cause is the first book to trace the century-long hunt for a human cancer virus in America, an effort whose scale exceeded that of the Human Genome Project. The government’s campaign merged the worlds of molecular biology, public health, and military planning in the name of translating laboratory discoveries into useful medical therapies. However, its expansion into biomedical research sparked fierce conflict. Many biologists dismissed the suggestion that research should be planned and the idea of curing cancer by a vaccine or any other means as unrealistic, if not dangerous. Although the American hunt was ultimately fruitless, this effort nonetheless profoundly shaped our understanding of life at its most fundamental levels. A Contagious Cause links laboratory and legislature as has rarely been done before, creating a new chapter in the histories of science and American politics.
Author : E. J. Corey,Barbara Czakó,László Kürti
Publisher : John Wiley & Sons
Page : 272 pages
File Size : 44,8 Mb
Release : 2012-02-28
Category : Science
ISBN : 9781118361733
Molecules and Medicine provides, for the first time ever, a completely integrated look at chemistry, biology, drug discovery, and medicine. It delves into the discovery, application, and mode of action of more than one hundred of the most significant molecules in use in modern medicine. Opening sections of the book provide a unique, clear, and concise introduction, which enables readers to understand chemical formulas.
