The Structure And Function Of Muscle Pharmacology And Disease

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The Structure and Function of Muscle

Author : Geoffrey Howard Bourne
Publisher : Unknown
Page : 489 pages
File Size : 51,8 Mb
Release : 1960
Category : Muscles
ISBN : OCLC:1024740412

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The Structure and Function of Muscle by Geoffrey Howard Bourne Pdf

The Structure and Function of Muscle V4

Author : Geoffrey Bourne
Publisher : Elsevier
Page : 592 pages
File Size : 41,8 Mb
Release : 2014-04-24
Category : Science
ISBN : 9780323161534

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The Structure and Function of Muscle V4 by Geoffrey Bourne Pdf

The Structure and Function of Muscle discusses relevant issues that directly affect both the structure and function of the muscular system. These issues are approached from different perspectives, such as biochemical and molecular. This book discusses several factors that can affect the condition and performance of the muscular system, both externally (parasitic and viral infections, nutritional deficiency, drugs) and internally (genetics and muscular degeneration). It also presents several types of myopathies and their distinctive traits compared to other diseases with similar symptoms. This text contains relevant information about the causes and effects of the afflictions of the muscular system. Students, medical practitioners, and researchers specializing in mycology will find this book invaluable.

The Structure and Function of Muscle

Author : Geoffrey Howard Bourne
Publisher : Unknown
Page : 489 pages
File Size : 47,7 Mb
Release : 1968
Category : Electronic
ISBN : OCLC:174391872

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The Structure and Function of Muscle by Geoffrey Howard Bourne Pdf

Skeletal Muscle Circulation

Author : Ronald J. Korthuis
Publisher : Morgan & Claypool Publishers
Page : 147 pages
File Size : 51,8 Mb
Release : 2011
Category : Medical
ISBN : 9781615041831

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Skeletal Muscle Circulation by Ronald J. Korthuis Pdf

The aim of this treatise is to summarize the current understanding of the mechanisms for blood flow control to skeletal muscle under resting conditions, how perfusion is elevated (exercise hyperemia) to meet the increased demand for oxygen and other substrates during exercise, mechanisms underlying the beneficial effects of regular physical activity on cardiovascular health, the regulation of transcapillary fluid filtration and protein flux across the microvascular exchange vessels, and the role of changes in the skeletal muscle circulation in pathologic states. Skeletal muscle is unique among organs in that its blood flow can change over a remarkably large range. Compared to blood flow at rest, muscle blood flow can increase by more than 20-fold on average during intense exercise, while perfusion of certain individual white muscles or portions of those muscles can increase by as much as 80-fold. This is compared to maximal increases of 4- to 6-fold in the coronary circulation during exercise. These increases in muscle perfusion are required to meet the enormous demands for oxygen and nutrients by the active muscles. Because of its large mass and the fact that skeletal muscles receive 25% of the cardiac output at rest, sympathetically mediated vasoconstriction in vessels supplying this tissue allows central hemodynamic variables (e.g., blood pressure) to be spared during stresses such as hypovolemic shock. Sympathetic vasoconstriction in skeletal muscle in such pathologic conditions also effectively shunts blood flow away from muscles to tissues that are more sensitive to reductions in their blood supply that might otherwise occur. Again, because of its large mass and percentage of cardiac output directed to skeletal muscle, alterations in blood vessel structure and function with chronic disease (e.g., hypertension) contribute significantly to the pathology of such disorders. Alterations in skeletal muscle vascular resistance and/or in the exchange properties of this vascular bed also modify transcapillary fluid filtration and solute movement across the microvascular barrier to influence muscle function and contribute to disease pathology. Finally, it is clear that exercise training induces an adaptive transformation to a protected phenotype in the vasculature supplying skeletal muscle and other tissues to promote overall cardiovascular health. Table of Contents: Introduction / Anatomy of Skeletal Muscle and Its Vascular Supply / Regulation of Vascular Tone in Skeletal Muscle / Exercise Hyperemia and Regulation of Tissue Oxygenation During Muscular Activity / Microvascular Fluid and Solute Exchange in Skeletal Muscle / Skeletal Muscle Circulation in Aging and Disease States: Protective Effects of Exercise / References

Mechanisms of Vascular Disease

Author : Robert Fitridge,M. M. Thompson
Publisher : University of Adelaide Press
Page : 589 pages
File Size : 47,7 Mb
Release : 2011
Category : Medical
ISBN : 9781922064004

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Mechanisms of Vascular Disease by Robert Fitridge,M. M. Thompson Pdf

New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.

Selected Health Conditions and Likelihood of Improvement with Treatment

Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Care Services,Committee on Identifying Disabling Medical Conditions Likely to Improve with Treatment
Publisher : National Academies Press
Page : 319 pages
File Size : 53,9 Mb
Release : 2020-07-12
Category : Medical
ISBN : 9780309670951

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Selected Health Conditions and Likelihood of Improvement with Treatment by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Care Services,Committee on Identifying Disabling Medical Conditions Likely to Improve with Treatment Pdf

The Social Security Administration (SSA) administers two programs that provide disability benefits: the Social Security Disability Insurance (SSDI) program and the Supplemental Security Income (SSI) program. SSDI provides disability benefits to people (under the full retirement age) who are no longer able to work because of a disabling medical condition. SSI provides income assistance for disabled, blind, and aged people who have limited income and resources regardless of their prior participation in the labor force. Both programs share a common disability determination process administered by SSA and state agencies as well as a common definition of disability for adults: "the inability to engage in any substantial gainful activity by reason of any medically determinable physical or mental impairment which can be expected to result in death or which has lasted or can be expected to last for a continuous period of not less than 12 months." Disabled workers might receive either SSDI benefits or SSI payments, or both, depending on their recent work history and current income and assets. Disabled workers might also receive benefits from other public programs such as workers' compensation, which insures against work-related illness or injuries occurring on the job, but those other programs have their own definitions and eligibility criteria. Selected Health Conditions and Likelihood of Improvement with Treatment identifies and defines the professionally accepted, standard measurements of outcomes improvement for medical conditions. This report also identifies specific, long-lasting medical conditions for adults in the categories of mental health disorders, cancers, and musculoskeletal disorders. Specifically, these conditions are disabling for a length of time, but typically don't result in permanently disabling limitations; are responsive to treatment; and after a specific length of time of treatment, improve to the point at which the conditions are no longer disabling.

Caffeine for the Sustainment of Mental Task Performance

Author : Institute of Medicine,Food and Nutrition Board,Committee on Military Nutrition Research
Publisher : National Academies Press
Page : 172 pages
File Size : 49,7 Mb
Release : 2002-01-07
Category : Medical
ISBN : 9780309082587

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Caffeine for the Sustainment of Mental Task Performance by Institute of Medicine,Food and Nutrition Board,Committee on Military Nutrition Research Pdf

This report from the Committee on Military Nutrition Research reviews the history of caffeine usage, the metabolism of caffeine, and its physiological effects. The effects of caffeine on physical performance, cognitive function and alertness, and alleviation of sleep deprivation impairments are discussed in light of recent scientific literature. The impact of caffeine consumption on various aspects of health, including cardiovascular disease, reproduction, bone mineral density, and fluid homeostasis are reviewed. The behavioral effects of caffeine are also discussed, including the effect of caffeine on reaction to stress, withdrawal effects, and detrimental effects of high intakes. The amounts of caffeine found to enhance vigilance and reaction time consistently are reviewed and recommendations are made with respect to amounts of caffeine appropriate for maintaining alertness of military personnel during field operations. Recommendations are also provided on the need for appropriate labeling of caffeine-containing supplements, and education of military personnel on the use of these supplements. A brief review of some alternatives to caffeine is also provided.

Hormones, Metabolism and the Benefits of Exercise

Author : Bruce Spiegelman
Publisher : Springer
Page : 108 pages
File Size : 44,5 Mb
Release : 2018-03-07
Category : Science
ISBN : 9783319727905

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Hormones, Metabolism and the Benefits of Exercise by Bruce Spiegelman Pdf

The world is faced with an epidemic of metabolic diseases such as obesity and type 2 diabetes. This is due to changes in dietary habits and the decrease in physical activity. Exercise is usually part of the prescription, the first line of defense, to prevent or treat metabolic disorders. However, we are still learning how and why exercise provides metabolic benefits in human health. This open access volume focuses on the cellular and molecular pathways that link exercise, muscle biology, hormones and metabolism. This will include novel “myokines” that might act as new therapeutic agents in the future.

Muscle Regeneration

Author : Alexander Mauro
Publisher : Raven Press (ID)
Page : 582 pages
File Size : 55,7 Mb
Release : 1979
Category : Medical
ISBN : UOM:39015015064226

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Muscle Regeneration by Alexander Mauro Pdf

Botulinum Neurotoxins

Author : Andreas Rummel,Thomas Binz
Publisher : Springer Science & Business Media
Page : 322 pages
File Size : 49,7 Mb
Release : 2012-12-14
Category : Medical
ISBN : 9783642335709

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Botulinum Neurotoxins by Andreas Rummel,Thomas Binz Pdf

The extremely potent substance botulinum neurotoxin (BoNT) has attracted much interest in diverse fields. Originally identified as cause for the rare but deadly disease botulism, military and terrorist intended to misuse this sophisticated molecule as biological weapon. This caused its classification as select agent category A by the Centers for Diseases Control and Prevention and the listing in the Biological and Toxin Weapons Convention. Later, the civilian use of BoNT as long acting peripheral muscle relaxant has turned this molecule into an indispensable pharmaceutical world wide with annual revenues >$1.5 billion. Also basic scientists value the botulinum neurotoxin as molecular tool for dissecting mechanisms of exocytosis. This book will cover the most recent molecular details of botulinum neurotoxin, its mechanism of action as well as its detection and application.

Research Awards Index

Author : Anonim
Publisher : Unknown
Page : 1308 pages
File Size : 52,5 Mb
Release : 1982
Category : Medicine
ISBN : MINN:30000008789053

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Research Awards Index by Anonim Pdf

Muscle Cell and Tissue

Author : Kunihiro Sakuma
Publisher : BoD – Books on Demand
Page : 488 pages
File Size : 45,7 Mb
Release : 2015-09-02
Category : Technology & Engineering
ISBN : 9789535121565

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Muscle Cell and Tissue by Kunihiro Sakuma Pdf

In order to complete tissue regeneration, various cells such as neuronal, skeletal, smooth, endothelial, and immune (e.g., macrophage) interact smoothly with each other. This book, Muscle Cells and Tissues, offers a wide range of topics such as stem cells, cell culture, biomaterials, epigenetics, therapeutics, and the creation of tissues and organs. Novel applications for cell and tissue engineering including cell therapy, tissue models, and disease pathology modeling are discussed. The book also deals with the functional role of autophagy in modulating muscle homeostasis and molecular mechanism regulating skeletal muscle mass. The chapters can be interesting for graduate students, postdocs, teachers, physicians, and for executives in biotech and pharmaceutical companies, as well as researchers in the fields of molecular biology and regenerative medicine.

Cellular Aspects of Smooth Muscle Function

Author : C. Y. Kao,Mary E. Carsten
Publisher : Cambridge University Press
Page : 324 pages
File Size : 51,7 Mb
Release : 1997-08-28
Category : Science
ISBN : 0521482100

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Cellular Aspects of Smooth Muscle Function by C. Y. Kao,Mary E. Carsten Pdf

Smooth muscles line many internal organs and, in general, are involved in moving fluids and slurry around the body. They are controlled by the action of hormones, by nervous stimulation, and can be influenced by drugs. This 1997 book provides a review of our understanding of smooth muscle and integrates molecular, cellular and physiological information with tissue and anatomical studies. Well-known researchers have written chapters giving detailed reviews of our current knowledge of the biochemistry, pharmacology, physiology and anatomy of smooth muscle. In particular, they cover the seven most important areas of smooth muscle function including morphology, electrophysiology, mechanisms of electromechanical and pharmacomechanical coupling, calcium homeostasis, signal transduction, mechanics of contraction, and the contractile proteins. All those interested in muscular contraction will find this book worthwhile, whether they are biochemists, physiologists, or cell biologists.