Thioredoxin And Glutaredoxin Systems

Author : Jean-Pierre Jacquot,Mirko Zaffagnini
Publisher : MDPI
Page : 280 pages
File Size : 41,7 Mb
Release : 2019-05-10
Category : Science
ISBN : 9783038978367

Get Book

Thioredoxin and Glutaredoxin Systems by Jean-Pierre Jacquot,Mirko Zaffagnini Pdf

This Special Issue features recent data concerning thioredoxins and glutaredoxins from various biological systems, including bacteria, mammals, and plants. Four of the sixteen articles are review papers that deal with the regulation of development of the effect of hydrogen peroxide and the interactions between oxidants and reductants, the description of methionine sulfoxide reductases, detoxification enzymes that require thioredoxin or glutaredoxin, and the response of plants to cold stress, respectively. This is followed by eleven research articles that focus on a reductant of thioredoxin in bacteria, a thioredoxin reductase, and a variety of plant and bacterial thioredoxins, including the m, f, o, and h isoforms and their targets. Various parameters are studied, including genetic, structural, and physiological properties of these systems. The redox regulation of monodehydroascorbate reductase, aminolevulinic acid dehydratase, and cytosolic isocitrate dehydrogenase could have very important consequences in plant metabolism. Also, the properties of the mitochondrial o-type thioredoxins and their unexpected capacity to bind iron–sulfur center (ISC) structures open new developments concerning the redox mitochondrial function and possibly ISC assembly in mitochondria. The final paper discusses interesting biotechnological applications of thioredoxin for breadmaking.

Author : Arne Holmgren
Publisher : Raven Press (ID)
Page : 440 pages
File Size : 52,9 Mb
Release : 1986
Category : Medical
ISBN : UOM:39015010670472

Get Book

Thioredoxin and Glutaredoxin Systems by Arne Holmgren Pdf

Author : Anonim
Publisher : Unknown
Page : 0 pages
File Size : 52,5 Mb
Release : 2019
Category : Electronic
ISBN : OCLC:1368435624

Get Book

Thioredoxin and Glutaredoxin Systems by Anonim Pdf

This Special Issue features recent data concerning thioredoxins and glutaredoxins from various biological systems, including bacteria, mammals, and plants. Four of the sixteen articles are review papers that deal with the regulation of development of the effect of hydrogen peroxide and the interactions between oxidants and reductants, the description of methionine sulfoxide reductases, detoxification enzymes that require thioredoxin or glutaredoxin, and the response of plants to cold stress, respectively. This is followed by eleven research articles that focus on a reductant of thioredoxin in bacteria, a thioredoxin reductase, and a variety of plant and bacterial thioredoxins, including the m, f, o, and h isoforms and their targets. Various parameters are studied, including genetic, structural, and physiological properties of these systems. The redox regulation of monodehydroascorbate reductase, aminolevulinic acid dehydratase, and cytosolic isocitrate dehydrogenase could have very important consequences in plant metabolism. Also, the properties of the mitochondrial o-type thioredoxins and their unexpected capacity to bind iron-sulfur center (ISC) structures open new developments concerning the redox mitochondrial function and possibly ISC assembly in mitochondria. The final paper discusses interesting biotechnological applications of thioredoxin for breadmaking.

Author : Jean-Pierre Jacquot,Mirko Zaffagnini
Publisher : Unknown
Page : 280 pages
File Size : 47,5 Mb
Release : 2019
Category : Biology (General)
ISBN : 303897837X

Get Book

Thioredoxin and Glutaredoxin Systems by Jean-Pierre Jacquot,Mirko Zaffagnini Pdf

This Special Issue features recent data concerning thioredoxins and glutaredoxins from various biological systems, including bacteria, mammals, and plants. Four of the sixteen articles are review papers that deal with the regulation of development of the effect of hydrogen peroxide and the interactions between oxidants and reductants, the description of methionine sulfoxide reductases, detoxification enzymes that require thioredoxin or glutaredoxin, and the response of plants to cold stress, respectively. This is followed by eleven research articles that focus on a reductant of thioredoxin in bacteria, a thioredoxin reductase, and a variety of plant and bacterial thioredoxins, including the m, f, o, and h isoforms and their targets. Various parameters are studied, including genetic, structural, and physiological properties of these systems. The redox regulation of monodehydroascorbate reductase, aminolevulinic acid dehydratase, and cytosolic isocitrate dehydrogenase could have very important consequences in plant metabolism. Also, the properties of the mitochondrial o-type thioredoxins and their unexpected capacity to bind iron-sulfur center (ISC) structures open new developments concerning the redox mitochondrial function and possibly ISC assembly in mitochondria. The final paper discusses interesting biotechnological applications of thioredoxin for breadmaking.

Author : Eva-Mari Aro,B. Andersson
Publisher : Springer Science & Business Media
Page : 624 pages
File Size : 42,7 Mb
Release : 2006-04-11
Category : Science
ISBN : 9780306481482

Get Book

Regulation of Photosynthesis by Eva-Mari Aro,B. Andersson Pdf

This book covers the expression of photosynthesis related genes including regulation both at transcriptional and translational levels. It reviews biogenesis, turnover, and senescence of thylakoid pigment protein complexes and highlights some crucial regulatory steps in carbon metabolism.

Author : Kazuwa Nakao,Nagahiro Minato,Shinji Uemoto
Publisher : Springer
Page : 330 pages
File Size : 50,5 Mb
Release : 2015-10-13
Category : Science
ISBN : 9784431556510

Get Book

Innovative Medicine by Kazuwa Nakao,Nagahiro Minato,Shinji Uemoto Pdf

This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.

Author : Helmut Sies,Lester Packer
Publisher : Academic Press
Page : 550 pages
File Size : 51,7 Mb
Release : 2002
Category : Active oxygen
ISBN : 9780121822484

Get Book

Protein Sensors and Reactive Oxygen Species by Helmut Sies,Lester Packer Pdf

This volume of Methods in Enzymology is concerned with the rapidly developing field of selenoprotein synthesis and its related molecular genetics. Progressive information on the topics of proteins as redox sensors, selenoproteins, and the thioredoxin system is studied using methods such as bioinformatics, DNA chip technology, cell biology, molecular genetics, and enzymology. The information on novel selenoproteins identified from genomic sequence data, as well as current knowledge on glutathione peroxidases, selenoprotein P, iodothyronine deiodinases, and thioredoxin reductases, is presented in a method-based approach.

Author : Luc Montagnier,Rene Olivier,Catherine Pasquier
Publisher : CRC Press
Page : 578 pages
File Size : 54,5 Mb
Release : 1997-10-06
Category : Medical
ISBN : 1420002929

Get Book

Oxidative Stress in Cancer, AIDS, and Neurodegenerative Diseases by Luc Montagnier,Rene Olivier,Catherine Pasquier Pdf

Based on a conference on Oxidative Stress and Redox Regulation, held at the Pasteur Institute, Paris, this work examines fundamental, chemical, biological and medical studies of free radicals on different targets and the consequences of their reactivity. It covers the chemistry and biochemistry of free radicals, free radicals as second messengers that group the activation of transcription factors and enzymes, the importance of the antioxidant system in cell metabolism regulation, and the role of free radicals and antioxidants in disease management. The editors of this work are three of the most respected pioneers in the field. Dr. Montagnier is credited as the discoverer of HIV.

Author : Leopold Flohé,J. Robin Harris
Publisher : Springer Science & Business Media
Page : 409 pages
File Size : 49,5 Mb
Release : 2007-09-04
Category : Medical
ISBN : 9781402060519

Get Book

Peroxiredoxin Systems by Leopold Flohé,J. Robin Harris Pdf

This book contains a broad survey on the peroxiredoxins. It involves almost all groups that contributed significant insights into the emerging field. Coverage discusses the diverse biological roles of the new protein family in the context of other antioxidant systems like those based on heme or selenium catalysis. In addition, the book highlights related future perspectives.

Author : Anonim
Publisher : Unknown
Page : 128 pages
File Size : 45,5 Mb
Release : 19??
Category : Electronic
ISBN : 1461464382

Get Book

Encyclopedia of Signaling Molecules by Anonim Pdf

Author : Pinar Erkekoglu,Belma Kocer-Gumusel
Publisher : BoD – Books on Demand
Page : 94 pages
File Size : 52,7 Mb
Release : 2018-10-31
Category : Science
ISBN : 9781789842753

Get Book

Glutathione in Health and Disease by Pinar Erkekoglu,Belma Kocer-Gumusel Pdf

Reduced glutathione (GSH) is the most important thiol in living organisms. It is the key component of antioxidant system and serves as a free radical scavenger. There is a cycle of GSH in biological systems and this cycle provides higher intracellular levels of GSH. GSH depletion and apparent oxidative stress may cause toxicity and can affect the general well-being of the organism. GSH was shown to be preventive against aging, cancer, heart disease, infections and dementia. This book is mainly focused on GSH in health and disease. The readers will gain qualified scientific knowledge on the diverse functions of GSH, the importance of GSH status against oxidative stress and the interaction between GSH and nervous system-related infections from this book.

Author : Luis Moroder,Johannes Buchner (Prof.)
Publisher : Royal Society of Chemistry
Page : 453 pages
File Size : 52,5 Mb
Release : 2009
Category : Science
ISBN : 9780854041480

Get Book

Oxidative Folding of Peptides and Proteins by Luis Moroder,Johannes Buchner (Prof.) Pdf

With contributions from experts in the field, this book provides a comprehensive overview of the oxidative folding of cysteine-rich peptides.

Author : Roberta Masella,Giuseppe Mazza
Publisher : John Wiley & Sons
Page : 626 pages
File Size : 54,6 Mb
Release : 2009-08-06
Category : Technology & Engineering
ISBN : 9780470475966

Get Book

Glutathione and Sulfur Amino Acids in Human Health and Disease by Roberta Masella,Giuseppe Mazza Pdf

The complex roles of glutathione and sulfur amino acids in human health Glutathione (γ-L-glutamyl-L-cysteinylglycine, GSH) is a major antioxidant acting as a free radical scavenger that protects the cell from reactive oxygen species (ROS). Sulfur amino acids (SAAs), such as methionine and cysteine, play a critical role in the maintenance of health. GSH depletion as well as alterations of SAA metabolism are linked to a host of disease states including liver cirrhosis, various pulmonary diseases, myocardial ischemia and reperfusion injury, aging, Parkinson's disease, Alzheimer's disease, sepsis, and others. This book provides researchers with a comprehensive review of the biochemistry, absorption, metabolism, biological activities, disease prevention, and health promotion of glutathione and sulfur amino acids. The twenty-two chapters explore such topics as: Chemistry, absorption, transport, and metabolism of GSH and sulfur amino acids Antioxidant and detoxification properties of GSH and sulfur amino acids, highlighting the enzymatic systems involved in antioxidant defenses Biological activities of GSH and sulfur amino acids and their role in modulating cell processes Role of GSH and sulfur amino acid deficiency and alteration in the onset of diseases and in aging Protective effects exerted by GSH and sulfur amino acids when used as drugs, functional foods, and nutraceuticals in humans and animals Special attention is paid to the molecular mechanisms for the modulation of transcription factors and enzyme activities, as well as the nutritional and therapeutic significance of dietary sulfur amino acids as shown in human and animal models. With more than 2,000 scientific references, this book provides food scientists, nutritionists, biochemists, food technologists, chemists, molecular biologists, and public health professionals with a comprehensive and up-to-date examination of glutathione and sulfur amino acids in human health and disease.

Author : Dharmendra K. Gupta,José M. Palma,Francisco J. Corpas
Publisher : Springer
Page : 300 pages
File Size : 44,5 Mb
Release : 2018-03-10
Category : Science
ISBN : 9783319750880

Get Book

Antioxidants and Antioxidant Enzymes in Higher Plants by Dharmendra K. Gupta,José M. Palma,Francisco J. Corpas Pdf

This book provides an overview of antioxidants and antioxidant enzymes and their role in the mechanisms of signaling and cellular tolerance under stress in plant systems. Major reactive oxygen species (ROS)-scavenging/modulating enzymes include the superoxide dismutase (SOD) that dismutates O2 into H2O2, which is followed by the coordinated action of a set of enzymes including catalase (CAT), ascorbate peroxidase (APX), glutathione peroxidase (GPX) and peroxiredoxins (Prx) that remove H2O2. In addition to the ROS scavenging enzymes, a number of other enzymes are found in various subcellular compartments, which are involved in maintaining such redox homeostasis either by directly scavenging particular ROS and ROS-byproducts or by replenishing antioxidants. In that respect, these enzymes can be also considered antioxidants. Such enzymes include monodehydroascorbate reductase (MDAR), dehydroascorbate reductase (DHAR), glutathione reductase (GR), alternative oxidases (AOXs), peroxidases (PODs) and glutathione S-transferases (GSTs). Some non-enzymatic antioxidants, such as ascorbic acid (vitamin C), carotenes (provitamin A), tocopherols (vitamin E), and glutathione (GSH), work in concert with antioxidant enzymes to sustain an intracellular steady-state level of ROS that promotes plant growth, development, cell cycles and hormone signaling, and reinforces the responses to abiotic and biotic environmental stressors. Offering a unique compilation of information on antioxidants and antioxidant enzymes, this is a valuable resource for advanced students and researchers working on plant biochemistry, physiology, biotechnology, and signaling in cell organelles, and those specializing in plant enzyme technology.

Author : Manfred Lamprecht
Publisher : CRC Press
Page : 304 pages
File Size : 50,6 Mb
Release : 2014-09-17
Category : Medical
ISBN : 9781466567573

Get Book

Antioxidants in Sport Nutrition by Manfred Lamprecht Pdf

The use of antioxidants in sports is controversial due to existing evidence that they both support and hinder athletic performance. Antioxidants in Sport Nutrition covers antioxidant use in the athlete ́s basic nutrition and discusses the controversies surrounding the usefulness of antioxidant supplementation. The book also stresses how antioxidants may affect immunity, health, and exercise performance. The book contains scientifically based chapters explaining the basic mechanisms of exercise-induced oxidative damage. Also covered are methodological approaches to assess the effectiveness of antioxidant treatment. Biomarkers are discussed as a method to estimate the bioefficacy of dietary/supplemental antioxidants in sports. This book is useful for sport nutrition scientists, physicians, exercise physiologists, product developers, sport practitioners, coaches, top athletes, and recreational athletes. In it, they will find objective information and practical guidance.