Tissue Engineering For Tissue And Organ Regeneration

Author : Daniel Eberli,Sang Jin Lee,Andreas Traweger
Publisher : Springer
Page : 0 pages
File Size : 49,6 Mb
Release : 2021-04-22
Category : Technology & Engineering
ISBN : 3030442101

Get Book

Organ Tissue Engineering by Daniel Eberli,Sang Jin Lee,Andreas Traweger Pdf

The notion of being able to engineer complete organs has inspired an entire generation of researchers. While recent years have brought significant progress in regenerative medicine and tissue engineering, the immense challenges encountered when trying to engineer an entire organ have to be acknowledged. Despite a good understanding of cell phenotypes, cellular niches and cell-to-biomaterial interactions, the formation of tissues composed of multiple cells remains highly challenging. Only a step-by-step approach will allow the future production of a living tissue construct ready for implantation and to augment organ function. In this book, expert authors present the current state of this approach. It offers a concise overview and serves as a great starting point for anyone interested in the application of tissue engineering or regenerative medicine for organ engineering. Each chapter contains a short overview including physiological and pathological changes as well as the current clinical need. The potential cell sources and suitable biomaterials for each organ type are discussed and possibilities to produce organ-like structures are illustrated. The ultimate goal is for the generated small tissues to unfold their full potential in vivo and to serve as a native tissue equivalent. By integrating and evolving, these implants will form functional tissue in-vivo. This book discusses the desired outcome by focusing on well-defined functional readouts. Each chapter addresses the status of clinical translations and closes with the discussion of current bottlenecks and an outlook for the coming years. A successful regenerative medicine approach could solve organ shortage by providing biological substitutes for clinical use - clearly, this merits a collaborative effort.

Author : Daniel Eberli
Publisher : BoD – Books on Demand
Page : 470 pages
File Size : 45,5 Mb
Release : 2011-08-17
Category : Technology & Engineering
ISBN : 9789533076881

Get Book

Tissue Engineering for Tissue and Organ Regeneration by Daniel Eberli Pdf

Tissue Engineering may offer new treatment alternatives for organ replacement or repair deteriorated organs. Among the clinical applications of Tissue Engineering are the production of artificial skin for burn patients, tissue engineered trachea, cartilage for knee-replacement procedures, urinary bladder replacement, urethra substitutes and cellular therapies for the treatment of urinary incontinence. The Tissue Engineering approach has major advantages over traditional organ transplantation and circumvents the problem of organ shortage. Tissues reconstructed from readily available biopsy material induce only minimal or no immunogenicity when reimplanted in the patient. This book is aimed at anyone interested in the application of Tissue Engineering in different organ systems. It offers insights into a wide variety of strategies applying the principles of Tissue Engineering to tissue and organ regeneration.

Author : Nihal Vrana,Helena Knopf-Marques,Julien Barthes
Publisher : Woodhead Publishing
Page : 847 pages
File Size : 50,8 Mb
Release : 2020-03-20
Category : Medical
ISBN : 9780081029077

Get Book

Biomaterials for Organ and Tissue Regeneration by Nihal Vrana,Helena Knopf-Marques,Julien Barthes Pdf

Biomaterials for Organ and Tissue Regeneration: New Technologies and Future Prospects examines the use of biomaterials in applications related to artificial tissues and organs. With a strong focus on fundamental and traditional tissue engineering strategies, the book also examines how emerging and enabling technologies are being developed and applied. Sections provide essential information on biomaterial, cell properties and cell types used in organ generation. A section on state-of-the-art in organ regeneration for clinical purposes is followed by a discussion on enabling technologies, such as bioprinting, on chip organ systems and in silico simulations. Provides a systematic overview of the field, from fundamentals, to current challenges and opportunities Encompasses the classic paradigm of tissue engineering for creation of new functional tissue Discusses enabling technologies such as bioprinting, organ-on-chip systems and in silico simulations

Author : Naznin Sultana,Sanchita Bandyopadhyay-Ghosh,Chin Fhong Soon
Publisher : CRC Press
Page : 185 pages
File Size : 49,7 Mb
Release : 2020-02-04
Category : Technology & Engineering
ISBN : 9780429749629

Get Book

Tissue Engineering Strategies for Organ Regeneration by Naznin Sultana,Sanchita Bandyopadhyay-Ghosh,Chin Fhong Soon Pdf

Tissue Engineering Strategies for Organ Regeneration addresses the existing and future trends of tissue engineering approaches for organ/tissue regeneration or repair. This book provides a comprehensive summary of the recent improvement of biomaterials used in scaffold-based tissue engineering, and the tools and different protocols needed to design tissues and organs. The chapters in this book provide the in-depth principles for many of the supporting and enabling technologies including the applications of BioMEMS devices in tissue engineering, and the combination of organoid formation and three dimensional (3D) bioprinting. The book also highlights the advances and strategies for regeneration of three-dimensional microtissues in microcapsules, tissue reconstruction techniques, and injectable composite scaffolds for bone tissue repair and augmentation. Key Features: Addresses the current obstacles to tissue engineering applications Provides the latest improvements in the field of integrated biomaterials and fabrication techniques for scaffold-based tissue engineering Shows the influence of microenvironment towards cell-biomaterials interactions Highlights significant and recent improvements of tissue engineering applications for the artificial organ and tissue generation Describes the applications of microelectronic devices in tissue engineering Describes different current bioprinting technologies

Author : Lijie Grace Zhang,Ali Khademhosseini,Thomas Webster
Publisher : CRC Press
Page : 824 pages
File Size : 46,5 Mb
Release : 2016-04-19
Category : Medical
ISBN : 9789814411684

Get Book

Tissue and Organ Regeneration by Lijie Grace Zhang,Ali Khademhosseini,Thomas Webster Pdf

Tissue engineering aims to develop biological substitutes that restore, maintain, or improve damaged tissue and organ functionality. To date, numerous stem cells and biomaterials have been explored for a variety of tissue and organ regeneration. The challenge for existing stem cell-based techniques is that current therapies lack controlled environm

Author : Ioannis V. Yannas
Publisher : Springer
Page : 332 pages
File Size : 42,7 Mb
Release : 2014-11-21
Category : Technology & Engineering
ISBN : 9781493918652

Get Book

Tissue and Organ Regeneration in Adults by Ioannis V. Yannas Pdf

This textbook describes the basic principles of induced organ regeneration in skin and peripheral nerves and extends the original successful paradigm to other organs. A set of trans-organ rules is established and its use in regeneration of several organs is illustrated from the works of several independent investigators who worked with a variety of organs, such as the lung, the bladder, and the Achilles tendon, using collagen-based scaffolds somewhat similar to the original one. These critical medical treatments fill the clinical need that is not met by organ transplantation. New to this second edition: New information extending the paradigm of tissue regeneration from organ regeneration in skin and peripheral nerves to other organs Guidelines, known as trans-organ rules, are described for the first time for extending this unique medical treatment to organs of several medical specialties The work serves as a comprehensive text and reference for students and practitioners of tissue engineering

Author : Naznin Sultana,Sanchita Bandyopadhyay-Ghosh,Chin Fhong Soon
Publisher : CRC Press
Page : 273 pages
File Size : 48,7 Mb
Release : 2020-02-04
Category : Medical
ISBN : 9780429749612

Get Book

Tissue Engineering Strategies for Organ Regeneration by Naznin Sultana,Sanchita Bandyopadhyay-Ghosh,Chin Fhong Soon Pdf

Tissue Engineering Strategies for Organ Regeneration addresses the existing and future trends of tissue engineering approaches for organ/tissue regeneration or repair. This book provides a comprehensive summary of the recent improvement of biomaterials used in scaffold-based tissue engineering, and the tools and different protocols needed to design tissues and organs. The chapters in this book provide the in-depth principles for many of the supporting and enabling technologies including the applications of BioMEMS devices in tissue engineering, and the combination of organoid formation and three dimensional (3D) bioprinting. The book also highlights the advances and strategies for regeneration of three-dimensional microtissues in microcapsules, tissue reconstruction techniques, and injectable composite scaffolds for bone tissue repair and augmentation. Key Features: Addresses the current obstacles to tissue engineering applications Provides the latest improvements in the field of integrated biomaterials and fabrication techniques for scaffold-based tissue engineering Shows the influence of microenvironment towards cell-biomaterials interactions Highlights significant and recent improvements of tissue engineering applications for the artificial organ and tissue generation Describes the applications of microelectronic devices in tissue engineering Describes different current bioprinting technologies

Author : Ulrich Meyer,Thomas Meyer,Jörg Handschel,Hans Peter Wiesmann
Publisher : Springer Science & Business Media
Page : 1049 pages
File Size : 45,6 Mb
Release : 2009-02-11
Category : Medical
ISBN : 9783540777557

Get Book

Fundamentals of Tissue Engineering and Regenerative Medicine by Ulrich Meyer,Thomas Meyer,Jörg Handschel,Hans Peter Wiesmann Pdf

"Fundamentals of Tissue Engineering and Regenerative Medicine" provides a complete overview of the state of the art in tissue engineering and regenerative medicine. Tissue engineering has grown tremendously during the past decade. Advances in genetic medicine and stem cell technology have significantly improved the potential to influence cell and tissue performance, and have recently expanded the field towards regenerative medicine. In recent years a number of approaches have been used routinely in daily clinical practice, others have been introduced in clinical studies, and multitudes are in the preclinical testing phase. Because of these developments, there is a need to provide comprehensive and detailed information for researchers and clinicians on this rapidly expanding field. This book offers, in a single volume, the prerequisites of a comprehensive understanding of tissue engineering and regenerative medicine. The book is conceptualized according to a didactic approach (general aspects: social, economic, and ethical considerations; basic biological aspects of regenerative medicine: stem cell medicine, biomolecules, genetic engineering; classic methods of tissue engineering: cell, tissue, organ culture; biotechnological issues: scaffolds; bioreactors, laboratory work; and an extended medical discipline oriented approach: review of clinical use in the various medical specialties). The content of the book, written in 68 chapters by the world’s leading research and clinical specialists in their discipline, represents therefore the recent intellect, experience, and state of this bio-medical field.

Author : Ioannis V. Yannas
Publisher : Unknown
Page : 404 pages
File Size : 45,6 Mb
Release : 2014-01-15
Category : Electronic
ISBN : 147577558X

Get Book

Tissue and Organ Regeneration in Adults by Ioannis V. Yannas Pdf

Author : C.W. Patrick,A.G. Mikos,L.V. McIntire
Publisher : Elsevier
Page : 700 pages
File Size : 41,5 Mb
Release : 1998-02-20
Category : Technology & Engineering
ISBN : 0080532055

Get Book

Frontiers in Tissue Engineering by C.W. Patrick,A.G. Mikos,L.V. McIntire Pdf

Frontiers in Tissue Engineering is a carefully edited compilation of state-of-the-art contributions from an international authorship of experts in the diverse subjects that make up tissue engineering. A broad representation of the medical, scientific, industrial and regulatory community is detailed in the book. The work is an authoritative and comprehensive reference source for scientists and clinicians working in this emerging field. The book is divided into three parts: fundamentals and methods of tissue engineering, tissue engineering applied to specialised tissues, and tissue engineering applied to organs. The text offers many novel approaches, including a detailed coverage of cell-tissue interactions at cellular and molecular levels; cell-tissue surface, biochemical, and mechanical environments; biomaterials; engineering design; tissue-organ function; new approaches to tissue-organ regeneration and replacement of function; ethical considerations of tissue engineering; and government regulation of tissue-engineered products.

Author : John P. Fisher,Antonios G. Mikos,Joseph D. Bronzino,Donald R. Peterson
Publisher : CRC Press
Page : 801 pages
File Size : 51,8 Mb
Release : 2012-12-11
Category : Medical
ISBN : 9781439874004

Get Book

Tissue Engineering by John P. Fisher,Antonios G. Mikos,Joseph D. Bronzino,Donald R. Peterson Pdf

Tissue engineering research continues to captivate the interest of researchers and the general public alike. Popular media outlets like The New York Times, Time, and Wired continue to engage a wide audience and foster excitement for the field as regenerative medicine inches toward becoming a clinical reality. Putting the numerous advances in the field into a broad context, Tissue Engineering: Principles and Practices explores current thoughts on the development of engineered tissues. With contributions from experts and pioneers, this book begins with coverage of the fundamentals, details the supporting technology, and then elucidates their applications in tissue engineering. It explores strategic directions, nanobiomaterials, biomimetics, gene therapy, cell engineering, and more. The chapters then explore the applications of these technologies in areas such as bone engineering, cartilage tissue, dental tissue, vascular engineering, and neural engineering. A comprehensive overview of major research topics in tissue engineering, the book: Examines the properties of stem cells, primary cells, growth factors, and extracellular matrix as well as their impact on the development of tissue-engineered devices Focuses upon those strategies typically incorporated into tissue-engineered devices or utilized in their development, including scaffolds, nanocomposites, bioreactors, drug delivery systems, and gene therapy techniques Presents synthetic tissues and organs that are currently under development for regenerative medicine applications The contributing authors are a diverse group with backgrounds in academia, clinical medicine, and industry. Furthermore, this book includes contributions from Europe, Asia, and North America, helping to broaden the views on the development and application of tissue-engineered devices. The book provides a useful reference for courses devoted to tissue engineering fundamentals and those laboratories developing tissue-engineered devices for regenerative medicine therapy.

Author : W. Mark Saltzman
Publisher : Oxford University Press
Page : 544 pages
File Size : 55,8 Mb
Release : 2004-07-15
Category : Medical
ISBN : 0198032404

Get Book

Tissue Engineering by W. Mark Saltzman Pdf

Tissue or organ transplantation are among the few options available for patients with excessive skin loss, heart or liver failure, and many common ailments, and the demand for replacement tissue greatly exceeds the supply, even before one considers the serious constraints of immunological tissue type matching to avoid immune rejection. Tissue engineering promises to help sidestep constraints on availability and overcome the scientific challenges, with huge medical benefits. This book lays out the principles of tissue engineering. It will be a useful reference work for those associated with this field and as a textbook for specialized courses in the subject. It is a companion volume to Saltzman's OUP book on drug delivery.

Author : Robert Lanza,Robert Langer,Joseph P. Vacanti
Publisher : Elsevier
Page : 1039 pages
File Size : 53,8 Mb
Release : 2000-05-16
Category : Science
ISBN : 9780080539676

Get Book

Principles of Tissue Engineering by Robert Lanza,Robert Langer,Joseph P. Vacanti Pdf

The opportunity that tissue engineering provides for medicine is extraordinary. In the United States alone, over half-a-trillion dollars are spent each year to care for patients who suffer from tissue loss or dysfunction. Although numerous books and reviews have been written on tissue engineering, none has been as comprehensive in its defining of the field. Principles of Tissue Engineering combines in one volume the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation of applications of tissue engineering to diseases affecting specific organ systems. The first edition of the book, published in 1997, is the definite reference in the field. Since that time, however, the discipline has grown tremendously, and few experts would have been able to predict the explosion in our knowledge of gene expression, cell growth and differentiation, the variety of stem cells, new polymers and materials that are now available, or even the successful introduction of the first tissue-engineered products into the marketplace. There was a need for a new edition, and this need has been met with a product that defines and captures the sense of excitement, understanding and anticipation that has followed from the evolution of this fascinating and important field. Key Features* Provides vast, detailed analysis of research on all of the major systems of the human body, e.g., skin, muscle, cardiovascular, hematopoietic, and nerves* Essential to anyone working in the field* Educates and directs both the novice and advanced researcher* Provides vast, detailed analysis of research with all of the major systems of the human body, e.g. skin, muscle, cardiovascular, hematopoietic, and nerves* Has new chapters written by leaders in the latest areas of research, such as fetal tissue engineering and the universal cell* Considered the definitive reference in the field* List of contributors reads like a "who's who" of tissue engineering, and includes Robert Langer, Joseph Vacanti, Charles Vacanti, Robert Nerem, A. Hari Reddi, Gail Naughton, George Whitesides, Doug Lauffenburger, and Eugene Bell, among others

Author : Chandra P. Sharma,Thomas Chandy,Vinoy Thomas,Finosh G. Thankam
Publisher : Academic Press
Page : 724 pages
File Size : 40,7 Mb
Release : 2022-01-25
Category : Science
ISBN : 9780128240656

Get Book

Tissue Engineering by Chandra P. Sharma,Thomas Chandy,Vinoy Thomas,Finosh G. Thankam Pdf

Tissue Engineering: Current Status and Challenges bridges the gap between biomedical scientists and clinical practitioners. The work reviews the history of tissue engineering, covers the basics required for the beginner, and inspires those in the field toward future research and application emerging in this fast-moving field. Written by global experts in the field for those studying and researching tissue engineering, the book reviews regenerative technologies, stem cell research and regeneration of organs. It then moves to soft tissue engineering (heart, vascular, muscle and 3D scaffolding and printing), hard tissue engineering (bone, dental myocardial and musculoskeletal) and translational avenues in the field. Introduces readers to the history and benefits of tissue engineering Includes coverage of new techniques and technologies, such as nanotechnology and nanoengineering Presents concepts, ideology and theories which form the foundation for next-generation tissue engineering

Author : Anthony Atala,Robert Lanza
Publisher : Gulf Professional Publishing
Page : 580 pages
File Size : 41,7 Mb
Release : 2001-10-12
Category : Science
ISBN : 9780124366367

Get Book

Methods of Tissue Engineering by Anthony Atala,Robert Lanza Pdf

This reference book combines the tools, experimental protocols, detailed descriptions and know-how for the successful engineering of tissues and organs in one volume.