Torsades De Pointes

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Torsades de Pointes

James E. Tisdale
Torsades de Pointes Book PDF

Author : James E. Tisdale
Publisher : Academic Press
Page : 378 pages
File Size : 42,9 Mb
Release : 2022-03-17
Category : Medical
ISBN : 9780128214619

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Torsades de Pointes by James E. Tisdale Pdf

Over the past 25-30 years, deaths due to Torsades de Pointes (TdP) have resulted in numerous drugs being withdrawn from the market. However, nearly 200 drugs that may prolong the QT interval and cause TdP remain available. A number of drugs with the potential to cause TdP are among the top 200 most prescribed drugs in the US, whilst new information regarding TdP is emerging rapidly. The purpose of this book is to provide a comprehensive source of information on the topic of torsades de pointes (TdP), which is a life-threatening polymorphic ventricular tachyarrhythmia associated with QT interval prolongation on the electrocardiogram (ECG). Torsades de Pointes provides a detailed, up-to-date and emerging information related to the epidemiology, drug culprits, mechanisms, risk factors, and methods of prevention and management of the life-threatening polymorphic ventricular tachycardia, also known as torsades de pointes. The book contains current knowledge, incorporating recent and cutting-edge advances in understanding of topics including inherited channelopathies and congenital LQTS; drugs that cause QT interval prolongation and TdP; non-drug causes of acquired QT interval prolongation and TdP; epidemiology of inherited and acquired TdP; morbidity and mortality associated with TdP, particularly in association with specific antimicrobials, antidepressants and antipsychotics, and methadone; cellular and molecular mechanisms of TdP, traditional and emerging risk factors for TdP; methods of prevention and risk reduction for TdP; and clinical management of patients with TdP. This book is an essential reference for both clinicians and researchers – providing guidance for clinicians who care for patients receiving QT interval-prolonging drugs, as well as cutting edge information for scientists and investigators conducting research in the area. Up-to-date information on TdP associated with inherited channelopathies and the multiple forms of congenital LQTS Includes a wealth of new information emerging regarding TdP, including newly-described risk factors and cellular and molecular mechanisms, contributions of genetic polymorphisms to drug-induced TdP, methods of quantification of risk, and methods of risk reduction, including clinical decision support Contains information on nearly 200 commonly used drugs that have the potential to cause torsades de pointes, including antimicrobials, antipsychotics, antidepressants, antiarrhythmic agents, methadone, and many others An essential reference for clinicians and researchers – provides guidance for clinicians who care for patients receiving QT interval-prolonging drugs, as well as cutting edge information for scientists and investigators conducting research in the area

Acquired Long QT Syndrome

A. John Camm,Marek Malik,Yee Guan Yap
Acquired Long QT Syndrome Book PDF

Author : A. John Camm,Marek Malik,Yee Guan Yap
Publisher : John Wiley & Sons
Page : 208 pages
File Size : 45,8 Mb
Release : 2008-04-15
Category : Medical
ISBN : 9781405146166

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Acquired Long QT Syndrome by A. John Camm,Marek Malik,Yee Guan Yap Pdf

In recent years there has been considerable interest in the diagnosis and understanding of ventricular repolarisation, particularly the QT interval prolongation and abnormal T and T/U wave morphology associated with torsades de pointes. Advances in ion channel cloning have greatly improved our understanding of the role of ionic channels in mediating cardiac repolarisation. Unfortunately, it is increasingly recognised that a number of drugs, both those associated with altering repolarisation, and others for non-cardiac conditions can increase the propensity for polymorphic ventricular tachycardia, syncope and even ventricular fibrillation and sudden death. In this volume, arrhythmia specialists from St. George’s Hospital Medical School, London discuss the mechanisms behind QT prolongation and torsades de pointes. They focus particularly on the risk of individual cardiac and non-cardiac drugs in provoking long QT syndrome, providing a comprehensive review which will be useful for all electrophysiologists treating polymorphic ventricular tachycardias, and will expose important regulatory issues for pharmaceutical authorities and for the wider medical community.

Drug-Induced Long QT Syndrome

Yee Guan Yap,A. John Camm
Drug Induced Long QT Syndrome Book PDF

Author : Yee Guan Yap,A. John Camm
Publisher : Wiley-Blackwell
Page : 120 pages
File Size : 40,8 Mb
Release : 2002-09-10
Category : Medical
ISBN : 0879934689

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Drug-Induced Long QT Syndrome by Yee Guan Yap,A. John Camm Pdf

To most cardiologists, the long QT syndrome is a relatively rare congenital and familial syndrome that affects children or young adults. However, in addition to congenital LQTS there is a series of acquired forms of the syndrome, usually resulting from exposure to drugs that extend the duration the QT interval. This prolongation may be the primary pharmacodynamic action of the drug, however a plethora of other drugs, including some types of antibiotic, antipsychotics, antidepressants, antimalarials and antihistamines may provoke QT interval prolongation. The aim of the Clinical Approaches to Tachyarryhthmias series is to update the physician, cardiologist, and all those responsible for the the care of patients with cardiac arrhythmias. In this volume, Dr. Yap and Dr. Camm expose the data implicating a large number of drugs as potential QT prolongators.

Cardiology Explained

Euan A. Ashley,Euan Ashley,Josef Niebauer
Cardiology Explained Book PDF

Author : Euan A. Ashley,Euan Ashley,Josef Niebauer
Publisher : Remedica
Page : 258 pages
File Size : 45,6 Mb
Release : 2004
Category : Cardiology
ISBN : 9781901346220

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Cardiology Explained by Euan A. Ashley,Euan Ashley,Josef Niebauer Pdf

One of the most time-consuming tasks in clinical medicine is seeking the opinions of specialist colleagues. There is a pressure not only to make referrals appropriate but also to summarize the case in the language of the specialist. This book explains basic physiologic and pathophysiologic mechanisms of cardiovascular disease in a straightforward manner, gives guidelines as to when referral is appropriate, and, uniquely, explains what the specialist is likely to do. It is ideal for any hospital doctor, generalist, or even senior medical student who may need a cardiology opinion, or for that ma.

Ventricular Arrhythmias

John M. Miller
Ventricular Arrhythmias Book PDF

Author : John M. Miller
Publisher : Unknown
Page : 0 pages
File Size : 54,7 Mb
Release : 2008
Category : Arrhythmia
ISBN : 1416062750

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Ventricular Arrhythmias by John M. Miller Pdf

Ventricular arrhythmias cause most cases of sudden cardiac death, which is the leading cause of death in the US. This issue reviews the causes of arrhythmias and the promising new drugs and devices to treat arrhythmias.

Challenging Cases and Complication Management in Pain Medicine

Magdalena Anitescu,Honorio T. Benzon,Mark S. Wallace
Challenging Cases and Complication Management in Pain Medicine Book PDF

Author : Magdalena Anitescu,Honorio T. Benzon,Mark S. Wallace
Publisher : Springer
Page : 346 pages
File Size : 46,7 Mb
Release : 2017-11-17
Category : Medical
ISBN : 9783319600727

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Challenging Cases and Complication Management in Pain Medicine by Magdalena Anitescu,Honorio T. Benzon,Mark S. Wallace Pdf

This comprehensive book provides reviews of pain management complications that arise in clinical practice. Organized into sections focused on types of pain therapy and procedures, each chapter is based on actual complications; starting with a case description that delineates the context with a short past medical and surgical history, pain management technique and outcome it is followed by a comprehensive review of the topic described in the first section. Authors emphasize the elements of differential diagnosis that pointed towards establishing of the complication and describe the best way to treat the identified complication. Physicians treating pain patients will be presented the necessary tools in identifying and treating unanticipated complications following pain interventions, thus providing safer care for their patients.

Clinical Arrhythmology and Electrophysiology E-Book

Ziad Issa,John M. Miller,Douglas P. Zipes
Clinical Arrhythmology and Electrophysiology E Book Book PDF

Author : Ziad Issa,John M. Miller,Douglas P. Zipes
Publisher : Elsevier Health Sciences
Page : 752 pages
File Size : 48,6 Mb
Release : 2018-08-07
Category : Medical
ISBN : 9780323568821

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Clinical Arrhythmology and Electrophysiology E-Book by Ziad Issa,John M. Miller,Douglas P. Zipes Pdf

Part of the highly regarded Braunwald’s family of cardiology references, Clinical Arrhythmology and Electrophysiology, 3rd Edition, offers complete coverage of the latest diagnosis and management options for patients with arrhythmias. Expanded clinical content and clear illustrations keep you fully abreast of current technologies, new syndromes and diagnostic procedures, new information on molecular genetics, advances in ablation, and much more.

ABC of Clinical Electrocardiography

Francis Morris,William J. Brady,A. John Camm
ABC of Clinical Electrocardiography Book PDF

Author : Francis Morris,William J. Brady,A. John Camm
Publisher : John Wiley & Sons
Page : 112 pages
File Size : 43,9 Mb
Release : 2009-04-15
Category : Medical
ISBN : 9781444312492

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ABC of Clinical Electrocardiography by Francis Morris,William J. Brady,A. John Camm Pdf

Electrocardiography is an essential tool in diagnosing cardiacdisorders. This second edition of the ABC of ClinicalElectrocardiography allows readers to become familiar with the widerange of patterns seen in the electrocardiogram in clinicalpractice and covers the fundamentals of ECG interpretation andanalysis. Fully revised and updated, this edition includes a self-assessmentsection to aid revision and check comprehension, clear anatomicaldiagrams to illustrate key points and a larger format to show12-lead ECGs clearly and without truncation. Edited and written by leading experts, the ABC of ClinicalElectrocardiography is a valuable text for anyone managing patientswith heart disorders, both in general practice and in hospitals.Junior doctors and nurses, especially those working in cardiologyand emergency departments, as well as medical students, will findthis a vaulable introduction to the understanding of this keyclinical tool.

Management of Cardiac Arrhythmias

Gan-Xin Yan,Peter R. Kowey,Charles Antzelevitch
Management of Cardiac Arrhythmias Book PDF

Author : Gan-Xin Yan,Peter R. Kowey,Charles Antzelevitch
Publisher : Springer Nature
Page : 870 pages
File Size : 45,8 Mb
Release : 2020-07-27
Category : Medical
ISBN : 9783030419677

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Management of Cardiac Arrhythmias by Gan-Xin Yan,Peter R. Kowey,Charles Antzelevitch Pdf

A significantly expanded third edition, this book provides a comprehensive and concise overview of cardiac arrhythmias and their ECG/telemetry manifestations, including the principles of cardiac electrophysiology, current concepts of pharmacology, clinical features, diagnoses, and state-of-the-art treatments. Additionally, the book emphasizes decision-making strategies in approaching each individual patient and the application of technical innovations in specific clinical situations. Organized into eight parts, beginning chapters introduce the concepts and principles of cardiac electrophysiology, unique rhythms, and ECG waves/signs. These chapters are designed to integrate emerging knowledge in basic science and clinical medicine. Subsequent chapters focus on the diagnosis of a variety of cardiac arrhythmias using non-invasive methodology. Throughout the book, chapters continue to analyze pharmacological and other approaches to therapy of specific arrhythmias, including supraventricular tachycardias, atrial fibrillation and flutter, ventricular arrhythmias, and bradyarrhythmias. Finally, the book closes with coverage on inherited cardiac arrhythmia syndromes including the long, short QT, and J-wave syndromes, catecholaminergic polymorphic ventricular tachycardia, and arrhythmogenic right ventricular cardiomyopathy. The third edition of Management of Cardiac Arrhythmias, is an essential resource for physicians, residents, fellows, and medical students in cardiology, cardiac surgery, vascular surgery, cardiac electrophysiology, and cardiac radiology.

Electrocardiogram in Clinical Medicine

Michael J. Lipinski,Andrew E. Darby,Michael C. Bond,Nathan P. Charlton,Korin B. Hudson,Kelly Williamson
Electrocardiogram in Clinical Medicine Book PDF

Author : Michael J. Lipinski,Andrew E. Darby,Michael C. Bond,Nathan P. Charlton,Korin B. Hudson,Kelly Williamson
Publisher : John Wiley & Sons
Page : 510 pages
File Size : 53,7 Mb
Release : 2020-12-07
Category : Medical
ISBN : 9781118754559

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Electrocardiogram in Clinical Medicine by Michael J. Lipinski,Andrew E. Darby,Michael C. Bond,Nathan P. Charlton,Korin B. Hudson,Kelly Williamson Pdf

Offers a guide for a complete understanding of the disease and conditions most frequently revealed in ECGs recorded in the acute, critical, and emergency care settings Electrocardiogram in Clinical Medicine offers an authoritative guide to ECG interpretation that contains a focus and perspective from each of the three primary areas of medical care: acute care, critical care and emergency care. It can be used as a companion with the book ECGs for the Emergency Physician I & II (by Mattu and Brady) or as a stand-alone text. These three books can be described as a cumulative EGG reference for the medical provider who uses the electrocardiogram on a regular basis. Electrocardiogram in Clinical Medicine includes sections on all primary areas of ECG interpretation and application as well as sections that highlight use, devices and strategies. The medical content covers acute coronary syndromes and all related issues, other diseases of the myocardium, morphologic syndromes, toxicology and paediatrics; dysrhythmias will also be covered in detail. This important resource: • Goes beyond pattern recognition in ECGs to offer a real understanding of the clinical syndromes evidenced in ECGs and implications for treatment • Covers the indications, advantages and pitfalls of the use of ECGs for diagnosis in all acute care settings, from EMS to ED to Critical Care • Examines the ECG in toxic, metabolic and environmental presentations; critical information for acute care clinicians who need to be able to differentiate ODs, poisoning and other environmental causes from MI or other cardiac events • Facilitates clinical decision-making Written for practicing ER, general medicine, family practice, hospitalist and ICU physicians and medical students, Electrocardiogram in Clinical Medicine is an important book for the accurate interpretation of EGG results.

The Brugada Syndrome

Charles Antzelevitch
The Brugada Syndrome Book PDF

Author : Charles Antzelevitch
Publisher : John Wiley & Sons
Page : 248 pages
File Size : 52,9 Mb
Release : 2008-04-15
Category : Medical
ISBN : 9781405146814

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The Brugada Syndrome by Charles Antzelevitch Pdf

Until recently, the cellular basis for sudden death, the BrugadaSyndrome, has largely remained an unknown to modernarrhythmologists and cardiologists, particularly in the absence ofany structural heart disease. Detailed observations of age-groups,especially the young, families and populations where sudden deathfrequently occurs, and improved understanding of its contributoryfactors and mechanisms are, however, showing the way forward. This addition to the Clinical Approaches to Tachyarrhythmias(CATA) Series, written by the investigators who discovered andprobed the Brugada Syndrome, discusses the history, etiology,pathology and clinical manifestations of sudden death. Fromdiagnosis, prognosis, to therapeutic approaches using the latest incathater ablation techniques, electrophysiological surgery, andgenetic appraisal, the work is a testimony to the author'sinvestigation. Using clinical cases in Thailand and Laos, theyfurther unravel the syndrome's molecular mechanisms, studyingrelated syndromes, such as the long-QT syndrome, infant death, andarryhthmogenic right ventricular cardiomyopathy. By being informed of the electrophysiological abnormalities thatcontribute to familial and genetic diseases, physicians,cardiologists and all those who care for patients with cardiacarrhythmias will be better able to identify and treat patients inwhom the Brugada Syndrome may strike next.

Basis and Treatment of Cardiac Arrhythmias

Robert E. Kass,Colleen E. Clancy
Basis and Treatment of Cardiac Arrhythmias Book PDF

Author : Robert E. Kass,Colleen E. Clancy
Publisher : Springer Science & Business Media
Page : 384 pages
File Size : 45,9 Mb
Release : 2005-09-29
Category : Medical
ISBN : 3540249672

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Basis and Treatment of Cardiac Arrhythmias by Robert E. Kass,Colleen E. Clancy Pdf

This book incorporates the most up-to date information related to mechanisms and treatment of cardiac arrhythmia. Many of the topics discussed in this text reflect very recently undertaken research directions including genetics of arrhythmias, cell signalling molecules as potential therapeutic targets and trafficking to the membrane. These new approaches and implementations of anti-arrhythmic therapy derive from many decades of research as outlined in the first chapter by distinguished Professors Michael Rosen (Columbia University) and Michiel Janse (University of Amsterdam). The text covers changes in approaches to therapy over time, arrhythmias in multiple cardiac regions and over many scales, from gene to protein to cell to tissue to organ.

Pocket Guide to the American Board of Emergency Medicine In-Training Exam

Bob Cambridge
Pocket Guide to the American Board of Emergency Medicine In Training Exam Book PDF

Author : Bob Cambridge
Publisher : Cambridge University Press
Page : 257 pages
File Size : 50,9 Mb
Release : 2013-07-04
Category : Medical
ISBN : 9781107696266

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Pocket Guide to the American Board of Emergency Medicine In-Training Exam by Bob Cambridge Pdf

A portable, comprehensive revision guide for resident physicians preparing for the ABEM Emergency Medicine In-Training Exam.

Physics, Pharmacology and Physiology for Anaesthetists

Matthew E. Cross,Emma V. E. Plunkett
Physics Pharmacology and Physiology for Anaesthetists Book PDF

Author : Matthew E. Cross,Emma V. E. Plunkett
Publisher : Cambridge University Press
Page : 439 pages
File Size : 40,5 Mb
Release : 2014-03-06
Category : Medical
ISBN : 9781107615885

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Physics, Pharmacology and Physiology for Anaesthetists by Matthew E. Cross,Emma V. E. Plunkett Pdf

A quick reference to basic science for anaesthetists, containing all the key information needed for FRCA exams.

Cardiac Repolarization

Ihor Gussak,Charles Antzelevitch,Stephen C. Hammill,Win K. Shen,Preben Bjerregaard
Cardiac Repolarization Book PDF

Author : Ihor Gussak,Charles Antzelevitch,Stephen C. Hammill,Win K. Shen,Preben Bjerregaard
Publisher : Springer Science & Business Media
Page : 549 pages
File Size : 55,9 Mb
Release : 2003-03-13
Category : Medical
ISBN : 9781592593620

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Cardiac Repolarization by Ihor Gussak,Charles Antzelevitch,Stephen C. Hammill,Win K. Shen,Preben Bjerregaard Pdf

A comprehensive review of all the latest developments in cardiac electrophysiology, focusing on both the clinical and experimental aspects of ventricular repolarization, including newly discovered clinical repolarization syndromes, electrocardiographic phenomena, and their correlation with the most recent advances in basic science. The authors illuminate the basic electrophysiologic, molecular, and pharmacologic mechanisms underlying ventricular repolarization, relate them to specific disease conditions, and examine the future of antiarrhythmic drug development based on both molecular and electrophysiological properties. They also fully review the clinical presentation and management of specific cardiac repolarization conditions.