Toxoplasmosis

Author : Louis M. Weiss,Kami Kim
Publisher : Academic Press
Page : 1160 pages
File Size : 52,8 Mb
Release : 2013-08-10
Category : Science
ISBN : 9780123965363

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Toxoplasma Gondii by Louis M. Weiss,Kami Kim Pdf

This 2e of Toxoplasma gondii reflects the significant advances in the field in the last 5 years, including new information on the genomics, epigenomics and proteomics of T. gondii as well as a new understanding of the population biology and genetic diversity of this organism. T. gondii remains the best model system for studying the entire Apicomplexa group of protozoans, which includes Malaria, making this new edition essential for a broad group of researchers and scientists. Toxoplasmosis is caused by a one-celled protozoan parasite known as T. gondii. The infection produces a wide range of clinical syndromes in humans, land and sea mammals, and various bird species. Most humans contract toxoplasmosis by eating contaminated, raw or undercooked meat (particularly pork), vegetables, or milk products; by coming into contact with the T. gondii eggs from cat feces; or by drinking contaminated water. The parasite damages the ocular and central nervous systems, causing behavioral and personality alterations as well as fatal necrotizing encephalitis. It is especially dangerous for the fetus of an infected pregnant woman and for individuals with compromised immune systems, such as HIV-infected patients. Completely updated, the 2e presents recent advances driven by new information on the genetics and genomics of the pathogen Provides the latest information concerning the epidemiology, diagnosis, treatment and prevention of toxoplasmosis Offers a single-source reference for a wide range of scientists and physicians working with this pathogen, including parasitologists, cell and molecular biologists, veterinarians, neuroscientists, physicians, and food scientists

Author : E. Fuller Torrey
Publisher : Springer Nature
Page : 150 pages
File Size : 50,8 Mb
Release : 2021-11-29
Category : Medical
ISBN : 9783030868116

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Parasites, Pussycats and Psychosis by E. Fuller Torrey Pdf

This open access book analyzes the evidence linking Toxoplasma gondii to the increasing incidence of schizophrenia and bipolar disorder in the United States. Initially establishing that infectious agents are regularly transmitted from animals to humans, lead to human disease, and that infectious agents can cause psychosis, it then examines the protozoan parasite Toxoplasma gondii in detail. Infecting 40 million Americans, Toxoplasma gondii is known to cause congenital infections, eye disease, and encephalitis for individuals who are immunosuppressed. It has also been shown to change the behavior of nonhuman mammals, as well as to alter some personality traits in humans. After discussing the clinical evidence linking Toxoplasma gondii to human psychosis, the book elucidates the epidemiological evidence further supporting this linkage; including the proportional increase in incidence of human psychosis as cats transitioned to domestication over 800 years. Finally, the book assesses the magnitude of the problem and suggests solutions. Parasites, Pussycats and Psychosis: The Unknown Dangers of Human Toxoplasmosis provides a comprehensive review of the evidence linking human psychosis in the United States to infections of Toxoplasma gondii. It will be of interest to infectious disease specialists, general practitioners, scientists, historians, and cat-lovers.

Author : J. P. Dubey
Publisher : CRC Press
Page : 336 pages
File Size : 46,6 Mb
Release : 2016-04-19
Category : Medical
ISBN : 9781420092370

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Toxoplasmosis of Animals and Humans by J. P. Dubey Pdf

Found worldwide from Alaska to Australasia, Toxoplasma gondii knows no geographic boundaries. The protozoan is the source of one of the most common parasitic infections in humans, livestock, companion animals, and wildlife, and has gained notoriety with its inclusion on the list of potential bioterrorism microbes. In the two decades since the publi

Author : Christopher J. Tonkin
Publisher : Humana
Page : 0 pages
File Size : 51,8 Mb
Release : 2019-11-23
Category : Medical
ISBN : 1493998560

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Toxoplasma gondii by Christopher J. Tonkin Pdf

This volume covers a diverse collection of protocols currently being used by the Toxoplasma research community, and also looks at innovative methods that are pushing the boundaries of possibilities. Chapters in this book discuss topics such as isolation and genotyping of Toxoplasma gondii strains; assessing rhoptry secretion in T. gondii; plate-based quantification of stimulated Toxoplasma egress; methods to study ocular toxoplasmosis; and metabolic analysis of Toxoplasma gondii tachyzoites. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Toxoplasma gondii: Methods and Protocols is a valuable resource for students or groups starting off in the field, as well as laboratories interested in implementing the latest techniques described in the book.

Author : Yogesh Dwivedi
Publisher : CRC Press
Page : 485 pages
File Size : 42,7 Mb
Release : 2012-06-25
Category : Medical
ISBN : 9781439838815

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The Neurobiological Basis of Suicide by Yogesh Dwivedi Pdf

With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.

Author : Uwe Gross
Publisher : Springer Science & Business Media
Page : 268 pages
File Size : 46,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642510144

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Toxoplasma gondii by Uwe Gross Pdf

For years, toxoplasmosis has been known as disease mostly affecting newborns. Since immunocompromised patients (AIDS) present a high risk of reactivation of chronic toxoplasmosis this parasitic disease has gained increasing interest. Besides presenting clinical and therapeutical concepts, this volume provides current knowledge about genetics and immunology of T. gondii and the interaction with its 'host'. Since in vivo and in vitro models of toxoplasmosis exist, and genetic manipulation has become possible, this protozoan parasite has recently been accepted as a model for understanding the pathogenesis and persistance of other intracellular parasites. The articles of the book compromise both reviewing current concepts and reporting on yet unpublished results of leading scientists in this field.

Author : Katia Denise Saraiva Bresciani,Alvimar Jose da Costa
Publisher : Bentham Science Publishers
Page : 136 pages
File Size : 50,9 Mb
Release : 2018-05-08
Category : Medical
ISBN : 9781681086439

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Congenital Toxoplasmosis in Humans and Domestic Animals by Katia Denise Saraiva Bresciani,Alvimar Jose da Costa Pdf

Congenital Toxoplasmosis in Humans and Domestic Animals presents information about Toxoplasma gondii and its infection in neonates and different animals (cats, cattle, dogs, goats, pigs and sheep). Readers will have quick access to the pathophysiology, diagnosis, reproductive disorders (such as abortion, neonatal mortality and prematurity) and treatment of both human and veterinary toxoplasmosis. In addition, important aspects for control programs of congenital toxoplasmosis and for maternal and neonatal screening in such control programs are discussed. Thus readers will be better equipped to conduct prevention programmes and routine diagnosis of zoonotic infections related to T. gondii. This handbook is of interest to epidemiologists, doctors, veterinarians and public health specialists.

Author : Phyllis E. Kozarsky,Paul M. Arguin,Ava W. Navin
Publisher : Mosby
Page : 0 pages
File Size : 47,7 Mb
Release : 2005
Category : Travel
ISBN : 032303716X

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Health Information for International Travel 2005-2006 by Phyllis E. Kozarsky,Paul M. Arguin,Ava W. Navin Pdf

The cutting-edge new edition of the Centers for Disease Control and Prevention's famed "Yellow Book" is the most authoritative guide of its kind, with vital pre-travel healthcare tips and essential information on health risks abroad. It includes vaccination recommendations and disease prevention strategies for HIV/AIDS, cholera, hepatitis, influenza, plague, SARS, smallpox, viral hemorrhagic fevers, and many other illnesses.

Author : Fabrice Chretien,Kum Thong Wong,Leroy R. Sharer
Publisher : John Wiley & Sons
Page : 850 pages
File Size : 51,8 Mb
Release : 2020-01-08
Category : Medical
ISBN : 9781119467793

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Infections of the Central Nervous System by Fabrice Chretien,Kum Thong Wong,Leroy R. Sharer Pdf

Der neue Band aus der Reihe International Society of Neuropathology wurde anlässlich der British Medical Association (BMA) Awards 2019 wärmstens empfohlen. Die Herausgeber sind Experten des Fachgebiets und beschreiben Infektionen des Nervensystems mit ihren klinischen, pathologischen und genetischen Eigenheiten. Auch seltene Erkrankungen werden in übersichtlichen Kapiteln erläutert, zusammen mit Definitionen, mikrobiologischen Eigenschaften, Epidemiologie, klinischen Ausprägungen, Labortests, Pathologie, Genetik und Behandlungsoptionen.

Author : Darrel O. Ho-yen,Alex W. L. Joss
Publisher : Oxford University Press, USA
Page : 288 pages
File Size : 53,6 Mb
Release : 1992
Category : Medical
ISBN : UOM:39015025188015

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Human Toxoplasmosis by Darrel O. Ho-yen,Alex W. L. Joss Pdf

Toxoplasmosis, a world-wide infection of animals and humans, may produce severe congenital abnormalities in pregnancy, while among the immunocompromised (malignancies, organ transplant, or human immunodeficiency virus infection), death may result. Toxoplasmosis is likely to become more common, and those who manage high-risk patients must be aware of the infection, and the latest techniques for minimizing its serious complications. Women need testing consistent with medical defence advice as well as advice on avoiding infection. This comprehensive volume contains chapters on the history of toxoplasmosis, its clinical features and life cycle, diagnosis management, prevention, and possible future developments. Animal infection, with its important economic and human implications, is considered separately. The appendix contains a detailed treatment of common questions that arise in pregnancy, which will help practitioners explain the condition to their patients. This important book will be of value to medical practitioners and other professionals dealing with toxoplasmosis.

Author : Paul H. Smith
Publisher : Unknown
Page : 52 pages
File Size : 41,9 Mb
Release : 1975
Category : Toxoplasmosis
ISBN : UVA:X030490807

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Toxoplasma and Toxoplasmosis by Paul H. Smith Pdf

Author : Janice C. Swanson
Publisher : Unknown
Page : 68 pages
File Size : 41,6 Mb
Release : 1990
Category : Government publications
ISBN : MINN:319510029775788

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Toxoplasmosis by Janice C. Swanson Pdf

Author : J.P. Dubey,A. Hemphill,R. Calero-Bernal,Gereon Schares
Publisher : CRC Press
Page : 512 pages
File Size : 47,5 Mb
Release : 2017-07-12
Category : Medical
ISBN : 9781351648608

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Neosporosis in Animals by J.P. Dubey,A. Hemphill,R. Calero-Bernal,Gereon Schares Pdf

Key features: Written by the scientist who named this parasite and was the first to set up proper diagnostic techniques Serves as the first ever book to provide information on the parasite structure, biology, pathogenesis, clinical signs, epidemiology, prevention, and control of neosporosis Covers both approaches toward preventing & controlling this disease: Developing an efficacious vaccine and sound cattle management practices Contains a wealth of illustrations, including many of the author's original photographs of the parasite Provides basic information on immunologic and molecular aspects of the disease Abortion is a worldwide problem in the livestock industry accounting for annual economic losses of billions of dollars, and N. caninum is a major cause of it. Neosporosis is a newly recognized disease of animals. Until 1988 it was misdiagnosed as toxoplasmosis. Considerable progress in understanding the biology of neosporosis has been made in the last 30 years, resulting in more than 2,000 scientific publications. The economic importance of abortion in cattle, and the availability of knowledge, reagents, and technology used to study toxoplasmosis, have contributed to the rapid progress in understanding the biology of neosporosis. Written by pioneers in this field, Neosporosis in Animals presents a comprehensive summary of the biology of neosporosis, starting with chapter 1 on the historical background of the discovery of the disease. Subsequent chapters deal with general aspects of the biology of N. caninum (chapter 2), techniques (chapter 3), and the disease caused by this parasite in cattle (chapter 4), dogs (chapter 5), and all other animals including sheep, pigs, primates and humans (chapters 6-18). This book provides, for the first time in a single authoritative source, a complete account of the structure, biology, clinical disease, diagnosis, epidemiology, treatment, attempts at immunoprophylaxis, and control in all hosts. There are 175 illustrations and tables devoted to the life cycle, structure of parasitic stages, and lesions. More than 2100 references are cited, allowing the reader to locate additional information on specific topics in an efficient way. This book will be useful to a broad range of researchers in biology and veterinarians.

Author : Louis M. Weiss,Kami Kim
Publisher : Elsevier
Page : 800 pages
File Size : 42,5 Mb
Release : 2011-04-28
Category : Science
ISBN : 0080475019

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Toxoplasma Gondii by Louis M. Weiss,Kami Kim Pdf

Toxoplasmosis is caused by a one-celled protozoan parasite known as Toxoplasma gondii. In the United States, it is estimated that approximately 30% of cats, the primary carriers, have been infected by T. gondii. Most humans contract toxoplasmosis by eating cyst-contaminated raw or undercooked meat, vegetables, or milk products or when they come into contact with the T. gondii eggs from cat feaces while cleaning a cat's litterbox, gardening, or playing in a sandbox. Approx 1 in 4 (more than 60 million) people in the USA are infected with the parasite, and in the UK between 0.5 and 1% of individuals become infected each year. By the age of 50, 40% of people test positive for the parasite. The predilection of this parasite is for the central nervous system (CNS) causing behavioral and personality alterations as well as fatal necrotizing encephalitis, and is especially dangerous for HIV infected patients. Though there have been tremendous strides in our understanding of the biology of Toxoplasma gondii in the last decade, there has been no systemic review of all of the information that has accumulated. Toxoplasma gondii provides the first comprehensive summary of literature on this organism by leading experts in the field who were responsible for organising the 7th International Congress on Toxoplasmosis in May 2003. It offeres systematic reviews of the biology of this pathogen as well as descriptions of the methods and resources used. Within the next year the T. gondii genome will be completed making this an indispensable research resource for biologists, physicians, parasitologists, and for all those contemplating experiments using T. gondii. * Serves as a model for understanding invasion of host cells by parasites, immune response, motility, differentiation, phylogenetics, evolution and organelle acquisition * Discusses the protocols related to genetic manipulation, cell biology and animal models while also providing reference material on available resources for working with this organism

Author : Joseph B. Cantey
Publisher : Springer
Page : 261 pages
File Size : 45,7 Mb
Release : 2018-06-18
Category : Medical
ISBN : 9783319900384

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Neonatal Infections by Joseph B. Cantey Pdf

There are approximately 4 million newborns annually in the United States, including 400,000 infants born preterm. This care occurs in nurseries of all acuity levels, sizes, and regions across the country and is provided by a variety of providers, including pediatricians, family practice doctors, nurse practitioners, and physician assistants. The most common complication during the newborn period is suspected or proven infection – either those acquired during the delivery itself or before delivery in the womb. Indeed, 4 of the 8 most commonly-prescribed medications in newborns annually are antibiotics. Therefore, these providers must all be knowledgeable about the clinical presentation, epidemiology, and approach to diagnosis, treatment and prevention of neonatal infections. However, many of these nurseries do not have convenient access to pediatric infectious disease consultation or support, and would benefit from a convenient reference guide. This book effectively and succinctly covers the pathophysiology, epidemiology, clinical presentation, approach to diagnosis and treatment, and important aspects of preventative care for the most frequently encountered neonatal and congenital infections. The first section discusses common neonatal infections (i.e., those acquired during or after delivery), including sepsis, meningitis, pneumonia, and other focal infections. The second section covers the most frequently encountered congenital infections (i.e., those acquired via the placenta while the fetus is still in-utero). Finally, the concluding section discusses the basics of infection prevention in the nursery setting, including general principles of infection prevention, how to apply those principles to families, and how to manage a suspected outbreak of infection within a nursery. This book is a unique contribution to the field. Existing texts such as the AAP Red Book fold neonatal infections in within chapters on a given pathogen, but the information is difficult to find and access quickly. By covering neonatal and congenital infections thoroughly while still keeping each section clear and concise, this Handbook will be a valuable resource for the busy nursery provider.