Congenital Toxoplasmosis In Humans And Domestic Animals
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Congenital Toxoplasmosis in Humans and Domestic Animals by Katia Denise Saraiva Bresciani,Alvimar Jose da Costa Pdf
Congenital Toxoplasmosis in Humans and Domestic Animals presents information about Toxoplasma gondii and its infection in neonates and different animals (cats, cattle, dogs, goats, pigs and sheep). Readers will have quick access to the pathophysiology, diagnosis, reproductive disorders (such as abortion, neonatal mortality and prematurity) and treatment of both human and veterinary toxoplasmosis. In addition, important aspects for control programs of congenital toxoplasmosis and for maternal and neonatal screening in such control programs are discussed. Thus readers will be better equipped to conduct prevention programmes and routine diagnosis of zoonotic infections related to T. gondii. This handbook is of interest to epidemiologists, doctors, veterinarians and public health specialists.
Toxoplasmosis of Animals and Humans by J. P. Dubey Pdf
Found worldwide from Alaska to Australasia, Toxoplasma gondii knows no geographic boundaries. The protozoan is the source of one of the most common parasitic infections in humans, livestock, companion animals, and wildlife, and has gained notoriety with its inclusion on the list of potential bioterrorism microbes. In the two decades since the publi
Toxoplasmosis by Ionela Hotea ,Gheorghe Dărăbuș Pdf
Scientific motivation to publish this book comes from the increased interest in the study of toxoplasmosis, showed all over the world. Though the Toxoplasma gondii infection was first discovered in 1908, toxoplasmosis remains a today's research topic, a realm of questions and dilemmas that interest both the veterinarians and the human doctors. Studies in the field are directed to the epidemiology of the disease, the sources of infection, epidemiological chains, being underlined the important feature in the transmission of this parasite: the ability to pass from one intermediate host to another intermediate host without passing through the final host - felids. An increased prevalence of toxoplasmosis in humans and animals, as well as the difficulty of coproscopic diagnosis of toxoplasmosis in cats, expensive serological examinations in both animals and humans, lack of diagnostic methods accessible to veterinarians in slaughterhouses, cultural and culinary differences of human patients, which can influence the prevalence of the disease, motivate the scientific and practical importance of the proposed book and reveal the importance of this topic for animal and human health. So, the proposed book will contain informations regarding the etiology and history of Toxoplasma gondii infection and also the parasite's morphology and biology. This work will contain a very detailed epidemiology of the toxoplasmosis from all over the world and for all species of animals. This chapter will include also personal findings of the authors about the Toxoplasma gondii seroprevalence in domestic animals from Romania. In the last part of the book we will present the main methods for toxoplasma diagnosis. At the end of the book we will synthesize the main routes for T. gondii infection and the recommendations for reducing toxoplasmosis seroprevalence.
Parasites, Pussycats and Psychosis by E. Fuller Torrey Pdf
This open access book analyzes the evidence linking Toxoplasma gondii to the increasing incidence of schizophrenia and bipolar disorder in the United States. Initially establishing that infectious agents are regularly transmitted from animals to humans, lead to human disease, and that infectious agents can cause psychosis, it then examines the protozoan parasite Toxoplasma gondii in detail. Infecting 40 million Americans, Toxoplasma gondii is known to cause congenital infections, eye disease, and encephalitis for individuals who are immunosuppressed. It has also been shown to change the behavior of nonhuman mammals, as well as to alter some personality traits in humans. After discussing the clinical evidence linking Toxoplasma gondii to human psychosis, the book elucidates the epidemiological evidence further supporting this linkage; including the proportional increase in incidence of human psychosis as cats transitioned to domestication over 800 years. Finally, the book assesses the magnitude of the problem and suggests solutions. Parasites, Pussycats and Psychosis: The Unknown Dangers of Human Toxoplasmosis provides a comprehensive review of the evidence linking human psychosis in the United States to infections of Toxoplasma gondii. It will be of interest to infectious disease specialists, general practitioners, scientists, historians, and cat-lovers.
There are approximately 4 million newborns annually in the United States, including 400,000 infants born preterm. This care occurs in nurseries of all acuity levels, sizes, and regions across the country and is provided by a variety of providers, including pediatricians, family practice doctors, nurse practitioners, and physician assistants. The most common complication during the newborn period is suspected or proven infection – either those acquired during the delivery itself or before delivery in the womb. Indeed, 4 of the 8 most commonly-prescribed medications in newborns annually are antibiotics. Therefore, these providers must all be knowledgeable about the clinical presentation, epidemiology, and approach to diagnosis, treatment and prevention of neonatal infections. However, many of these nurseries do not have convenient access to pediatric infectious disease consultation or support, and would benefit from a convenient reference guide. This book effectively and succinctly covers the pathophysiology, epidemiology, clinical presentation, approach to diagnosis and treatment, and important aspects of preventative care for the most frequently encountered neonatal and congenital infections. The first section discusses common neonatal infections (i.e., those acquired during or after delivery), including sepsis, meningitis, pneumonia, and other focal infections. The second section covers the most frequently encountered congenital infections (i.e., those acquired via the placenta while the fetus is still in-utero). Finally, the concluding section discusses the basics of infection prevention in the nursery setting, including general principles of infection prevention, how to apply those principles to families, and how to manage a suspected outbreak of infection within a nursery. This book is a unique contribution to the field. Existing texts such as the AAP Red Book fold neonatal infections in within chapters on a given pathogen, but the information is difficult to find and access quickly. By covering neonatal and congenital infections thoroughly while still keeping each section clear and concise, this Handbook will be a valuable resource for the busy nursery provider.
This 2e of Toxoplasma gondii reflects the significant advances in the field in the last 5 years, including new information on the genomics, epigenomics and proteomics of T. gondii as well as a new understanding of the population biology and genetic diversity of this organism. T. gondii remains the best model system for studying the entire Apicomplexa group of protozoans, which includes Malaria, making this new edition essential for a broad group of researchers and scientists. Toxoplasmosis is caused by a one-celled protozoan parasite known as T. gondii. The infection produces a wide range of clinical syndromes in humans, land and sea mammals, and various bird species. Most humans contract toxoplasmosis by eating contaminated, raw or undercooked meat (particularly pork), vegetables, or milk products; by coming into contact with the T. gondii eggs from cat feces; or by drinking contaminated water. The parasite damages the ocular and central nervous systems, causing behavioral and personality alterations as well as fatal necrotizing encephalitis. It is especially dangerous for the fetus of an infected pregnant woman and for individuals with compromised immune systems, such as HIV-infected patients. Completely updated, the 2e presents recent advances driven by new information on the genetics and genomics of the pathogen Provides the latest information concerning the epidemiology, diagnosis, treatment and prevention of toxoplasmosis Offers a single-source reference for a wide range of scientists and physicians working with this pathogen, including parasitologists, cell and molecular biologists, veterinarians, neuroscientists, physicians, and food scientists
Handbook of Zoonoses E-Book by Joann Colville,David Berryhill Pdf
This essential, authoritative handbook provides clear, accurate coverage of zoonoses — diseases that can spread from animals to humans. The consistent format helps you quickly locate key information, such as how each disease affects the host, how it is spread, how it is treated, and necessary safety precautions. It also discusses the importance of educating animal owners about the public health implications of zoonoses and how to prevent them from spreading. Clear, concise coverage helps you respond quickly when presented with diseases that could potentially spread between patients, clients, and staff in the veterinary clinic. Each disease entry begins with a chart of its potential morbidity (the rate of incidence of a disease) and mortality (death rate), giving you at-a-glance access to the chance of contracting the disease and the severity of the disease if contracted. Clinically relevant coverage includes information on the etiology (bacterial, viral, parasitic, etc.), most common nonhuman hosts, transmission modes, course of the disease, clinical signs in animals and humans, diagnostic tests, prevention, and general advice. Essential information on preventing the spread of disease helps you educate clients about how to protect themselves and their animals from zoonoses. Coverage of diseases such as mad cow disease, West Nile virus, rabies, and anthrax, prepares you to answer client questions about diseases that are in the public eye.
Human Toxoplasmosis by Darrel O. Ho-yen,Alex W. L. Joss Pdf
Toxoplasmosis, a world-wide infection of animals and humans, may produce severe congenital abnormalities in pregnancy, while among the immunocompromised (malignancies, organ transplant, or human immunodeficiency virus infection), death may result. Toxoplasmosis is likely to become more common, and those who manage high-risk patients must be aware of the infection, and the latest techniques for minimizing its serious complications. Women need testing consistent with medical defence advice as well as advice on avoiding infection. This comprehensive volume contains chapters on the history of toxoplasmosis, its clinical features and life cycle, diagnosis management, prevention, and possible future developments. Animal infection, with its important economic and human implications, is considered separately. The appendix contains a detailed treatment of common questions that arise in pregnancy, which will help practitioners explain the condition to their patients. This important book will be of value to medical practitioners and other professionals dealing with toxoplasmosis.
Antiprotozoal Drug Discovery: A Challenge That Remains by Norma Rivera Pdf
Protozoan infections that are endemic in countries with limited economic resources pose a significant public health challenge to affected communities and some of these diseases are categorized as neglected tropical diseases by the World Health Organization. At the moment, there is an urgent need to identify and develop new antiprotozoal drugs. Antiprotozoal Drug Discovery: A Challenge That Remains brings together research from all scientists (including parasitologists, chemists, biologists among others) involved in the field of antiprotozoal experimental pharmacology, drug design and natural product research. The monograph is a compilation of review chapters written by experts on medical parasitology and pharmacology that covers a wide range of topics such as general characteristics of protozoan diseases (malaria, toxoplasmosis, Chagas’ disease, leishmaniasis, trichomoniasis) prophylaxis, treatments, natural products and rational drug design. The contents of this book are useful to medical microbiologists and pharmaceutical scientists seeking to update their knowledge about antiprotozoal drug design.
Intraocular Inflammation by Manfred Zierhut,Carlos Pavesio,Shigeaki Ohno,Fernando Orefice,Narsing A. Rao Pdf
This well-structured and lavishly illustrated book is a comprehensive reference on intraocular inflammation that encompasses all anatomic forms, settings and etiologies. Individual sections are devoted to uveitis associated with systemic disorders, uveitis syndromes restricted to the eye, bacterial uveitis, viral uveitis, fungal uveitis, parasitic uveitis, uveitis caused by other microbes, traumatic uveitis, and masquerade syndromes. Chapters on the different forms of uveitis are in a homogeneous reader-friendly format, with identification of core messages, explanation of etiology and pathogenesis, up-to-date information on diagnostics and differential diagnosis and guidance on the most appropriate forms of treatment and prognosis. Helpful flow charts are included to assist in identification of potential underlying disorders and the reader will also have online access to one hundred informative case reports demonstrating the different courses of intraocular inflammation. The authors are world experts keen to share their vast experience with the reader. Intraocular Inflammation will be a valuable resource for all physicians who deal with patients with inflammatory eye disease.
Toxoplasmosis of Animals and Humans, Second Edition by J. P. Dubey Pdf
Complete information on T. gondii infections in animals and man is summarized and analyzed in this thorough reference text. Critical in-formation on its economic impact and its effect on production of animals whose flesh is used for food is featured. The clinical and subclinical infections in all major species of livestock are pre-sented. For each animal species, worldwide serological prevalences are tabulated with T. gondii antibody titers, followed by an experi-mental section. Worldwide prevalences of T. gondii infections in mankind is summarized, highlighting epidemiology, symptom diag-nosis, treatment, and prevention. Past research is summarized and areas of future investigations are suggested. This book is highly useful to veterinarians, physicians, biologists, and researchers.
Human Emerging and Re-emerging Infections by Sunit Kumar Singh Pdf
Emerging and re-emerging pathogens pose several challenges to diagnosis, treatment, and public health surveillance, primarily because pathogen identification is a difficult and time-consuming process due to the “novel” nature of the agent. Proper identification requires a wide array of techniques, but the significance of these diagnostics is anticipated to increase with advances in newer molecular and nanobiotechnological interventions and health information technology. Human Emerging and Re-emerging Infections covers the epidemiology, pathogenesis, diagnostics, clinical features, and public health risks posed by new viral and microbial infections. The book includes detailed coverage on the molecular mechanisms of pathogenesis, development of various diagnostic tools, diagnostic assays and their limitations, key research priorities, and new technologies in infection diagnostics. Volume 1 addresses viral and parasitic infections, while volume 2 delves into bacterial and mycotic infections. Human Emerging and Re-emerging Infections is an invaluable resource for researchers in parasitologists, microbiology, Immunology, neurology and virology, as well as clinicians and students interested in understanding the current knowledge and future directions of infectious diseases.
