Transcriptional Regulation In Eukaryotes

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Transcriptional Regulation in Eukaryotes

Michael F. Carey,Stephen T. Smale
Transcriptional Regulation in Eukaryotes Book PDF

Author : Michael F. Carey,Stephen T. Smale
Publisher : CSHL Press
Page : 684 pages
File Size : 51,7 Mb
Release : 2000
Category : Medical
ISBN : 0879696354

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Transcriptional Regulation in Eukaryotes by Michael F. Carey,Stephen T. Smale Pdf

In the genome era, the analysis of gene expression has become a critical requirement in many laboratories. But there has been no comprehensive source of strategic, conceptual, and technical information to guide this often complex task. Transcriptional Regulation in Eukaryotes answers that need. Written by two experienced investigators, Michael Carey and Stephen Smale at the UCLA School of Medicine, and based in part on the Gene Expression course taught at Cold Spring Harbor Laboratory, this book directly addresses all the concerns of a laboratory studying the regulation of a newly isolated gene and the biochemistry of a new transcription factor. This important and unique book is essential reading for anyone pursuing the analysis of gene expression in model systems or disease states.

Transcriptional Regulation in Eukaryotes

Michael F. Carey,Craig L. Peterson,Stephen T. Smale
Transcriptional Regulation in Eukaryotes Book PDF

Author : Michael F. Carey,Craig L. Peterson,Stephen T. Smale
Publisher : Unknown
Page : 642 pages
File Size : 40,6 Mb
Release : 2009
Category : Genetic regulation
ISBN : STANFORD:36105132246492

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Transcriptional Regulation in Eukaryotes by Michael F. Carey,Craig L. Peterson,Stephen T. Smale Pdf

Covers the conceptual and practical aspects of how to study the regulation of a newly isolated gene and the biochemistry of a new transcription factor. This book puts methods in the context of underlying theory, and offers recommendations on experimental strategies.

Transcriptional Regulation in Eukaryotes

Michael F. Carey,Craig L. Peterson,Stephen T. Smale
Transcriptional Regulation in Eukaryotes Book PDF

Author : Michael F. Carey,Craig L. Peterson,Stephen T. Smale
Publisher : Unknown
Page : 0 pages
File Size : 52,7 Mb
Release : 2009
Category : Genetic regulation
ISBN : 0879697628

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Transcriptional Regulation in Eukaryotes by Michael F. Carey,Craig L. Peterson,Stephen T. Smale Pdf

Covers the conceptual and practical aspects of how to study the regulation of a newly isolated gene and the biochemistry of a new transcription factor. This book puts methods in the context of underlying theory, and offers recommendations on experimental strategies.

Gene Regulation in Eukaryotes

Edgar Wingender
Gene Regulation in Eukaryotes Book PDF

Author : Edgar Wingender
Publisher : Wiley-Blackwell
Page : 452 pages
File Size : 53,8 Mb
Release : 1993
Category : Science
ISBN : UOM:39015029969725

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Gene Regulation in Eukaryotes by Edgar Wingender Pdf

A much-needed guide through the overwhelming amount of literature in the field. Comprehensive and detailed, this book combines background information with the most recentinsights. It introduces current concepts, emphasizing the transcriptional control of genetic information. Moreover, it links data on the structure of regulatory proteins with basic cellular processes. Both advanced students and experts will find answers to such intriguing questions as: - How are programs of specific gene repertoires activated and controlled? - Which genes drive and control morphogenesis? - Which genes govern tissue-specific tasks? - How do hormones control gene expression in coordinating the activities of different tissues? An abundant number of clearly presented glossary terms facilitates understanding of the biological background. Speacial feature: over 2200 (!) literature references.

Gene Regulation

David S. Latchman
Gene Regulation Book PDF

Author : David S. Latchman
Publisher : Chapman & Hall
Page : 296 pages
File Size : 42,6 Mb
Release : 1995
Category : Medical
ISBN : UOM:39015047098168

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Gene Regulation by David S. Latchman Pdf

Gene Regulation provides a complete and concise picture of the processes regulating gene expression in higher organisms and man. The second edition of this well reviewed textbook has been extensively updated to reflect the scientific progress made in this area over the last four years.

Principles of Biology

Lisa Bartee,Walter Shiner,Catherine Creech
Principles of Biology Book PDF

Author : Lisa Bartee,Walter Shiner,Catherine Creech
Publisher : Unknown
Page : 128 pages
File Size : 40,7 Mb
Release : 2017
Category : Electronic
ISBN : 1636350410

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Principles of Biology by Lisa Bartee,Walter Shiner,Catherine Creech Pdf

The Principles of Biology sequence (BI 211, 212 and 213) introduces biology as a scientific discipline for students planning to major in biology and other science disciplines. Laboratories and classroom activities introduce techniques used to study biological processes and provide opportunities for students to develop their ability to conduct research.

Eucaryotic Gene Regulation

Richard Axel
Eucaryotic Gene Regulation Book PDF

Author : Richard Axel
Publisher : Elsevier
Page : 682 pages
File Size : 46,8 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780323143509

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Eucaryotic Gene Regulation by Richard Axel Pdf

Eukaryotic Gene Regulation covers the aspects and mechanisms of gene regulation of selected eukaryotes, such as yeast, Drosophila, and insect. This book is organized into eight parts, encompassing 52 chapters. The majority of the chapters are presented in an experimental manner containing an abstract, methods, results and discussion, and conclusion. This book first gives a short overview of the evolutionary role of interspersion in eukaryotic genes. It then presents considerable chapters on control of gene expression in yeast; gene mutation and isolation; structure and function; and analysis. Part III focuses on genetic and DNA sequence analysis in Drosophila. It includes discussions on allelic complementation and transvection, genetic organization, histone gene, and gene transcription. Part IV examines cell lineage; gene expression and sequences; and protein synthesis of insects, sea urchin, and mammalian cells. This is followed by discussions on structure and expression of specific eukaryotic genes from chicken, rat, rabbit, and human. Topics on the transfer of genetic information within and between cells and the structure and function of chromosome are significantly considered in Parts VI and VII. Genes evaluated in these sections include heavy chain immunoglobulin, light chain, beta-globin, and dihydrofolate reductase. Furthermore, this book describes the in vitro transcription and the factors involved; internal organization and mechanism of assembly of nucleosome; and chromatin structure. The concluding section focuses on aspects of viral genome expression including gene regulation, synthesis, processing, and alternative RNA splicing. Research biologists, geneticists, scientists, teachers, and students will greatly benefit from this book.

Cells: Molecules and Mechanisms

Eric Wong
Cells Molecules and Mechanisms Book PDF

Author : Eric Wong
Publisher : Axolotl Academic Publishing
Page : 283 pages
File Size : 41,8 Mb
Release : 2009
Category : Biology
ISBN : 9780985226114

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Cells: Molecules and Mechanisms by Eric Wong Pdf

"Yet another cell and molecular biology book? At the very least, you would think that if I was going to write a textbook, I should write one in an area that really needs one instead of a subject that already has multiple excellent and definitive books. So, why write this book, then? First, it's a course that I have enjoyed teaching for many years, so I am very familiar with what a student really needs to take away from this class within the time constraints of a semester. Second, because it is a course that many students take, there is a greater opportunity to make an impact on more students' pocketbooks than if I were to start off writing a book for a highly specialized upper- level course. And finally, it was fun to research and write, and can be revised easily for inclusion as part of our next textbook, High School Biology."--Open Textbook Library.

Post-Transcriptional Control of Gene Expression

John E.G. McCarthy,Mick F. Tuite
Post Transcriptional Control of Gene Expression Book PDF

Author : John E.G. McCarthy,Mick F. Tuite
Publisher : Springer Science & Business Media
Page : 650 pages
File Size : 55,6 Mb
Release : 2013-06-29
Category : Science
ISBN : 9783642751394

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Post-Transcriptional Control of Gene Expression by John E.G. McCarthy,Mick F. Tuite Pdf

The last ten years have witnessed a remarkable increase in our awareness of the importance of events subsequent to transcriptional initiation in terms of the regulation and control of gene expression. In particular, the development of recombinant DNA techniques that began in the 1970s provided powerful new tools with which to study the molecular basis of control and regulation at all levels. The resulting investigations revealed a diversity of post-transcriptional mechanisms in both prokaryotes and eukaryotes. Scientists working on translation, mRNA stability, transcriptional (anti)termination or other aspects of gene expression will often have met at specialist meetings for their own research area. However, only rarely do workers in different areas of post-transcriptional control/ regulation have the opportunity to meet under one roof. We therefore thought it was time to bring together leading representatives of most of the relevant areas in a small workshop intended to encourage interaction across the usual borders of research, both in terms of the processes studied, and with respect to the evolutionary division prokaryotes/eukaryotes. Given the breadth of topics covered and the restrictions in size imposed by the NATO workshop format, it was an extraordinarily difficult task to choose the participants. However, we regarded this first attempt as an experiment on a small scale, intended to explore the possibilities of a meeting of this kind. Judging by the response of the participants during and after the workshop, the effort had been worthwhile.

Mechanisms of Gene Regulation

Carsten Carlberg,Ferdinand Molnár
Mechanisms of Gene Regulation Book PDF

Author : Carsten Carlberg,Ferdinand Molnár
Publisher : Springer
Page : 211 pages
File Size : 48,7 Mb
Release : 2016-06-06
Category : Medical
ISBN : 9789401777414

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Mechanisms of Gene Regulation by Carsten Carlberg,Ferdinand Molnár Pdf

This textbook aims to describe the fascinating area of eukaryotic gene regulation for graduate students in all areas of the biomedical sciences. Gene expression is essential in shaping the various phenotypes of cells and tissues and as such, regulation of gene expression is a fundamental aspect of nearly all processes in physiology, both in healthy and in diseased states. This pivotal role for the regulation of gene expression makes this textbook essential reading for students of all the biomedical sciences, in order to be better prepared for their specialized disciplines. A complete understanding of transcription factors and the processes that alter their activity is a major goal of modern life science research. The availability of the whole human genome sequence (and that of other eukaryotic genomes) and the consequent development of next-generation sequencing technologies have significantly changed nearly all areas of the biological sciences. For example, the genome-wide location of histone modifications and transcription factor binding sites, such as provided by the ENCODE consortium, has greatly improved our understanding of gene regulation. Therefore, the focus of this book is the description of the post-genome understanding of gene regulation. The purpose of this book is to provide, in a condensed form, an overview on the present understanding of the mechanisms of gene regulation. The authors are not aiming to compete with comprehensive treatises, but rather focus on the essentials. Therefore, the authors have favored a high figure-to-text ratio following the rule stating that “a picture tells more than thousand words”. The content of the book is based on the lecture course, which is given by Prof. Carlberg since 2001 at the University of Eastern Finland in Kuopio. The book is subdivided into 4 sections and 13 chapters. Following the Introduction there are three sections, which take a view on gene regulation from the perspective of transcription factors, chromatin and non-coding RNA, respectively. Besides its value as a textbook, Mechanisms of Gene Regulation will be a useful reference for individuals working in biomedical laboratories.

Posttranscriptional Gene Regulation

Jane Wu
Posttranscriptional Gene Regulation Book PDF

Author : Jane Wu
Publisher : Unknown
Page : 0 pages
File Size : 46,6 Mb
Release : 2013
Category : Science
ISBN : 3527665439

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Posttranscriptional Gene Regulation by Jane Wu Pdf

2.4 Regulation of Transcription by Termination2.4.1 Transcription Attenuation, Promoter Upstream/Associated Transcription, and Pausing of RNApII; 2.4.2 Alternative Polyadenylation and Termination; 2.5 Mechanisms of Termination by Other RNA Polymerases; 2.6 Future Perspectives; Acknowledgments; References; 3: Posttranscriptional Gene Regulation by an Editor: ADAR and its Role in RNA Editing; 3.1 Introduction; 3.2 The RNA Editing Kinship; 3.3 The ADAR Gene Family; 3.4 The Role of RNA in the A-to-I Editing Mechanism; 3.5 Splice Site Alterations.

Mechanisms of Gene Regulation

Carsten Carlberg,Ferdinand Molnár
Mechanisms of Gene Regulation Book PDF

Author : Carsten Carlberg,Ferdinand Molnár
Publisher : Springer Science & Business Media
Page : 210 pages
File Size : 52,6 Mb
Release : 2013-12-11
Category : Medical
ISBN : 9789400779051

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Mechanisms of Gene Regulation by Carsten Carlberg,Ferdinand Molnár Pdf

This textbook aims to describe the fascinating area of eukaryotic gene regulation for graduate students in all areas of the biomedical sciences. Gene expression is essential in shaping the various phenotypes of cells and tissues and as such, regulation of expression is a fundamental aspect of nearly all processes in physiology, both in healthy and in diseased states. This pivotal role for the regulation of gene expression makes this textbook essential reading from students of all the biomedical sciences in order to be better prepared for their specialized disciplines. A complete understanding of transcription factors and the processes that alter their activity is a major goal of modern life science research. The availability of the whole human genome sequence (and that of other eukaryotic genomes) and the consequent development of next-generation sequencing technologies have significantly changed nearly all areas of the biological sciences. For example, the genome-wide location of histone modifications and transcription factor binding sites, such as provided by the ENCODE consortium, has greatly improved our understanding of gene regulation. Therefore, the focus of this book is the description of the post-genome understanding of gene regulation. The purpose of this book is to provide, in a condensed form, an overview on the present understanding of the mechanisms of gene regulation. The authors are not aiming to compete with comprehensive treatises, but rather focus on the essentials. Therefore, the authors have favored a high figure-to-text ratio following the rule which states that “a picture tells more than thousand words”. The content of the book is based on the lecture course, which is given by Prof. Carlberg since 2001 at the University of Eastern Finland in Kuopio. The book is subdivided into 4 sections and 13 chapters. Following the Introduction there are three sections, which take a view on gene regulation from the perspective of transcription factors, chromatin and non-coding RNA, respectively. Besides its value as a textbook, Mechanisms of Gene Regulation will be a useful reference for individuals working in biomedical laboratories.

Changes in Eukaryotic Gene Expression in Response to Environmental Stress

Burr Atkinson
Changes in Eukaryotic Gene Expression in Response to Environmental Stress Book PDF

Author : Burr Atkinson
Publisher : Elsevier
Page : 400 pages
File Size : 52,8 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780323162227

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Changes in Eukaryotic Gene Expression in Response to Environmental Stress by Burr Atkinson Pdf

Changes in Eukaryotic Gene Expression in Response to Environmental Stress focuses on various aspects of eukaryotic cell's response to heat stress (shock) and other stress stimuli. This book is organized into two major sections, encompassing 17 chapters that reflect the emphasis on research utilizing Drosophila, a variety of animal systems, and plants. This book first provides a brief introduction to the organization, sequences, and induction of heat shock proteins and related genes. It then describes the control of transcription during heat shock from the standpoint of molecular biology and evolutionary variations of the mechanisms in organisms with diverse metabolic needs. It goes on to discuss the issue of coordinate and noncoordinate responses of heat shock genes. It presents a model for post-transcriptional regulation on certain aspects of coordinate and noncoordinate regulations. Chapters 6-12 discuss heat shock proteins and genes and the effects of stress on gene expression of sea urchin, avian, and mammalian cells. The second part of the book focuses on the physiological role of heat shock proteins and genes in plants and fungi. It includes a discussion on experimental problems encountered during studies of the mechanisms of inhibition of photosynthesis by unfavorable environmental conditions. The changes in transcription and translation of specific mRNAs in the developing embryo during heat shock at various temperatures are described. The concluding chapters deal with heat shock response in plants, particularly the response in soybeans and maize, covering both physiological and molecular analyses. Research scientists, clinicians, and agriculturists will greatly benefit from the information presented in this book.

Biology for AP ® Courses

Julianne Zedalis,John Eggebrecht
Biology for AP Courses Book PDF

Author : Julianne Zedalis,John Eggebrecht
Publisher : Unknown
Page : 1923 pages
File Size : 55,9 Mb
Release : 2017-10-16
Category : Biology
ISBN : 1947172409

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Biology for AP ® Courses by Julianne Zedalis,John Eggebrecht Pdf

Biology for AP® courses covers the scope and sequence requirements of a typical two-semester Advanced Placement® biology course. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology for AP® Courses was designed to meet and exceed the requirements of the College Board’s AP® Biology framework while allowing significant flexibility for instructors. Each section of the book includes an introduction based on the AP® curriculum and includes rich features that engage students in scientific practice and AP® test preparation; it also highlights careers and research opportunities in biological sciences.

Gene Expression and Regulation in Mammalian Cells

Fumiaki Uchiumi
Gene Expression and Regulation in Mammalian Cells Book PDF

Author : Fumiaki Uchiumi
Publisher : BoD – Books on Demand
Page : 374 pages
File Size : 46,5 Mb
Release : 2018-02-28
Category : Medical
ISBN : 9789535138679

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Gene Expression and Regulation in Mammalian Cells by Fumiaki Uchiumi Pdf

Sixty years after the "central dogma," great achievements have been developed in molecular biology. We have also learned the important functions of noncoding RNAs and epigenetic regulations. More importantly, whole genome sequencing and transcriptome analyses enabled us to diagnose specific diseases. This book is not only intended for students and researchers working in laboratory but also physicians and pharmacists. This volume consists of 14 chapters, divided into 4 parts. Each chapter is written by experts investigating biological stresses, epigenetic regulation, and functions of transcription factors in human diseases. All articles presented in this volume by excellent investigators provide new insights into the studies in transcriptional control in mammalian cells and will inspire us to develop or establish novel therapeutics against human diseases.