Gene Regulation In Eukaryotes

Author : Michael F. Carey,Stephen T. Smale
Publisher : CSHL Press
Page : 684 pages
File Size : 46,8 Mb
Release : 2000
Category : Medical
ISBN : 0879696354

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Transcriptional Regulation in Eukaryotes by Michael F. Carey,Stephen T. Smale Pdf

In the genome era, the analysis of gene expression has become a critical requirement in many laboratories. But there has been no comprehensive source of strategic, conceptual, and technical information to guide this often complex task. Transcriptional Regulation in Eukaryotes answers that need. Written by two experienced investigators, Michael Carey and Stephen Smale at the UCLA School of Medicine, and based in part on the Gene Expression course taught at Cold Spring Harbor Laboratory, this book directly addresses all the concerns of a laboratory studying the regulation of a newly isolated gene and the biochemistry of a new transcription factor. This important and unique book is essential reading for anyone pursuing the analysis of gene expression in model systems or disease states.

Author : Edgar Wingender
Publisher : Wiley-Blackwell
Page : 452 pages
File Size : 55,6 Mb
Release : 1993
Category : Science
ISBN : UOM:39015029969725

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Gene Regulation in Eukaryotes by Edgar Wingender Pdf

A much-needed guide through the overwhelming amount of literature in the field. Comprehensive and detailed, this book combines background information with the most recentinsights. It introduces current concepts, emphasizing the transcriptional control of genetic information. Moreover, it links data on the structure of regulatory proteins with basic cellular processes. Both advanced students and experts will find answers to such intriguing questions as: - How are programs of specific gene repertoires activated and controlled? - Which genes drive and control morphogenesis? - Which genes govern tissue-specific tasks? - How do hormones control gene expression in coordinating the activities of different tissues? An abundant number of clearly presented glossary terms facilitates understanding of the biological background. Speacial feature: over 2200 (!) literature references.

Author : Gerald M. Kolodny
Publisher : CRC Press
Page : 326 pages
File Size : 40,6 Mb
Release : 2018-01-18
Category : Medical
ISBN : 9781351088831

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Eukaryotic Gene Regulation by Gerald M. Kolodny Pdf

The cause of cancer and its many manifestations is at present unknown. Since many of its manifestations, including is control of cell division, appear to represent abnormal patterns of gene expression, studies of the regulation of gene expression nwill provide important insights in the understanding and treatment of cancer. This volume attempts to present some of the recent work on regulation of gene expression in eukaryotic cells.

Author : David S. Latchman
Publisher : Nelson Thornes
Page : 360 pages
File Size : 54,7 Mb
Release : 1998
Category : Science
ISBN : UOM:39015042395528

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Gene Regulation by David S. Latchman Pdf

The previous editions of Gene Regulation have helped students in biological science and medicine gain a full understanding of the issues of gene regulation. In this edition, new material reflects the progress that has been made in the understanding of gene regulation. The most significant change is the addition of an extra chapter describing the basic processes by which DNA is converted in RNA and then into protein. This important new chapter makes this edition complete as a textbook on gene expression and its regulation.

Author : Ajit Kumar
Publisher : Springer Science & Business Media
Page : 238 pages
File Size : 43,6 Mb
Release : 2013-03-09
Category : Science
ISBN : 9781468474596

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Eukaryotic Gene Expression by Ajit Kumar Pdf

The recent surge of interest in recombinant DNA research is understandable considering that biologists from all disciplines, using recently developed mo lecular techniques, can now study with great precision the structure and regulation of specific genes. As a discipline, molecular biology is no longer a mere subspeciality of biology or biochemistry: it is the new biology. Current approaches to the outstanding problems in virtually all the traditional disci plines in biology are now being explored using the recombinant DNA tech nology. In this atmosphere of rapid progress, the role of information exchange and swift publication becomes quite crucial. Consequently, there has been an equally rapid proliferation of symposia volumes and review articles, apart from the explosion in popular science magazines and news media, which are always ready to simplify and sensationalize the implications of recent dis coveries, often before the scientific community has had the opportunity to fully scrutinize the developments. Since many of the recent findings in this field have practical implications, quite often the symposia in molecular biology are sponsored by private industry and are of specialized interest and in any case quite expensive for students to participate in. Given that George Wash ington University is a teaching institution, our aim in sponsoring these Annual Spring Symposia is to provide, at cost, a forum for students and experts to discuss the latest developments in selected areas of great significance in biology. Additionally, since the University is located in Washington, D. C.

Author : Carsten Carlberg,Ferdinand Molnár
Publisher : Springer Science & Business Media
Page : 214 pages
File Size : 42,5 Mb
Release : 2013-12-11
Category : Medical
ISBN : 9789400779051

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Mechanisms of Gene Regulation by Carsten Carlberg,Ferdinand Molnár Pdf

This textbook aims to describe the fascinating area of eukaryotic gene regulation for graduate students in all areas of the biomedical sciences. Gene expression is essential in shaping the various phenotypes of cells and tissues and as such, regulation of expression is a fundamental aspect of nearly all processes in physiology, both in healthy and in diseased states. This pivotal role for the regulation of gene expression makes this textbook essential reading from students of all the biomedical sciences in order to be better prepared for their specialized disciplines. A complete understanding of transcription factors and the processes that alter their activity is a major goal of modern life science research. The availability of the whole human genome sequence (and that of other eukaryotic genomes) and the consequent development of next-generation sequencing technologies have significantly changed nearly all areas of the biological sciences. For example, the genome-wide location of histone modifications and transcription factor binding sites, such as provided by the ENCODE consortium, has greatly improved our understanding of gene regulation. Therefore, the focus of this book is the description of the post-genome understanding of gene regulation. The purpose of this book is to provide, in a condensed form, an overview on the present understanding of the mechanisms of gene regulation. The authors are not aiming to compete with comprehensive treatises, but rather focus on the essentials. Therefore, the authors have favored a high figure-to-text ratio following the rule which states that “a picture tells more than thousand words”. The content of the book is based on the lecture course, which is given by Prof. Carlberg since 2001 at the University of Eastern Finland in Kuopio. The book is subdivided into 4 sections and 13 chapters. Following the Introduction there are three sections, which take a view on gene regulation from the perspective of transcription factors, chromatin and non-coding RNA, respectively. Besides its value as a textbook, Mechanisms of Gene Regulation will be a useful reference for individuals working in biomedical laboratories.

Author : Richard Axel
Publisher : Elsevier
Page : 682 pages
File Size : 50,8 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780323143509

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Eucaryotic Gene Regulation by Richard Axel Pdf

Eukaryotic Gene Regulation covers the aspects and mechanisms of gene regulation of selected eukaryotes, such as yeast, Drosophila, and insect. This book is organized into eight parts, encompassing 52 chapters. The majority of the chapters are presented in an experimental manner containing an abstract, methods, results and discussion, and conclusion. This book first gives a short overview of the evolutionary role of interspersion in eukaryotic genes. It then presents considerable chapters on control of gene expression in yeast; gene mutation and isolation; structure and function; and analysis. Part III focuses on genetic and DNA sequence analysis in Drosophila. It includes discussions on allelic complementation and transvection, genetic organization, histone gene, and gene transcription. Part IV examines cell lineage; gene expression and sequences; and protein synthesis of insects, sea urchin, and mammalian cells. This is followed by discussions on structure and expression of specific eukaryotic genes from chicken, rat, rabbit, and human. Topics on the transfer of genetic information within and between cells and the structure and function of chromosome are significantly considered in Parts VI and VII. Genes evaluated in these sections include heavy chain immunoglobulin, light chain, beta-globin, and dihydrofolate reductase. Furthermore, this book describes the in vitro transcription and the factors involved; internal organization and mechanism of assembly of nucleosome; and chromatin structure. The concluding section focuses on aspects of viral genome expression including gene regulation, synthesis, processing, and alternative RNA splicing. Research biologists, geneticists, scientists, teachers, and students will greatly benefit from this book.

Author : David Latchman
Publisher : Garland Science
Page : 405 pages
File Size : 43,6 Mb
Release : 2007-01-25
Category : Medical
ISBN : 9780203016336

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Gene Regulation by David Latchman Pdf

Gene regulation is an essential process in the development and maintenance of a healthy body, and as such, is a central focus in both basic science and medical research. Gene Regulation, Fifth Edition provides the student and researcher with a clear, up-to-date description of gene regulation in eukaryotes, distilling the vast and complex primary literature into a concise overview.

Author : Anonim
Publisher : Unknown
Page : 248 pages
File Size : 45,9 Mb
Release : 1980
Category : Cells
ISBN : UOM:39015004362904

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Eukaryotic Gene Regulation by Anonim Pdf

Author : Jane Wu
Publisher : Unknown
Page : 0 pages
File Size : 52,6 Mb
Release : 2013
Category : Science
ISBN : 3527665439

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Posttranscriptional Gene Regulation by Jane Wu Pdf

2.4 Regulation of Transcription by Termination2.4.1 Transcription Attenuation, Promoter Upstream/Associated Transcription, and Pausing of RNApII; 2.4.2 Alternative Polyadenylation and Termination; 2.5 Mechanisms of Termination by Other RNA Polymerases; 2.6 Future Perspectives; Acknowledgments; References; 3: Posttranscriptional Gene Regulation by an Editor: ADAR and its Role in RNA Editing; 3.1 Introduction; 3.2 The RNA Editing Kinship; 3.3 The ADAR Gene Family; 3.4 The Role of RNA in the A-to-I Editing Mechanism; 3.5 Splice Site Alterations.

Author : David Latchman,David S. Latchman
Publisher : Academic Press
Page : 488 pages
File Size : 53,9 Mb
Release : 2010-07-28
Category : Science
ISBN : 0080561039

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Eukaryotic Transcription Factors by David Latchman,David S. Latchman Pdf

Transcription, or the process by which DNA produces RNA, is a central aspect of gene expression. Transcription factors regulate transcription during development and in disease states. As such, it is critical for researchers to gain a good understanding of the relationship between the structure of various families of transcription factors and their function, as well as roles in human disease. Since publication of the Fourth Edition, there have been major advances, notably in the areas of chromatin remodeling and genome-scale analyses. This complete update includes all new coverage of the latest developments, from enabling genomic technologies to studies on the importance of post-translational modifications beyond phosphorylation events. Potential of transcription factors as therapeutic targets in human disease Importance of histone modifications Use of genome-based sequence analysis and high-throughput methods Applications of the chromatin immunoprecipitation (ChIP) assay Transcriptional elongation Regulation by post-translational modifications Regulatory networks and bioinformatics

Author : Athanasios Papavassiliou
Publisher : International Thomson Publishing Services
Page : 388 pages
File Size : 55,9 Mb
Release : 1997
Category : Cellular signal transduction
ISBN : STANFORD:36105019363014

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Transcription Factors in Eukaryotes by Athanasios Papavassiliou Pdf

Author : Julianne Zedalis,John Eggebrecht
Publisher : Unknown
Page : 1923 pages
File Size : 40,8 Mb
Release : 2017-10-16
Category : Biology
ISBN : 1947172409

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Biology for AP ® Courses by Julianne Zedalis,John Eggebrecht Pdf

Biology for AP® courses covers the scope and sequence requirements of a typical two-semester Advanced Placement® biology course. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology for AP® Courses was designed to meet and exceed the requirements of the College Board’s AP® Biology framework while allowing significant flexibility for instructors. Each section of the book includes an introduction based on the AP® curriculum and includes rich features that engage students in scientific practice and AP® test preparation; it also highlights careers and research opportunities in biological sciences.

Author : Lisa Bartee,Walter Shiner,Catherine Creech
Publisher : Unknown
Page : 128 pages
File Size : 46,5 Mb
Release : 2017
Category : Electronic
ISBN : 1636350410

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Principles of Biology by Lisa Bartee,Walter Shiner,Catherine Creech Pdf

The Principles of Biology sequence (BI 211, 212 and 213) introduces biology as a scientific discipline for students planning to major in biology and other science disciplines. Laboratories and classroom activities introduce techniques used to study biological processes and provide opportunities for students to develop their ability to conduct research.

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 48,9 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf