Transfer And Expression Of Eukaryotic Genes

Author : H.S. Ginsberg
Publisher : Academic Press
Page : 304 pages
File Size : 52,5 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780323138659

Get Book

Transfer and Expression of Eukaryotic Genes by H.S. Ginsberg Pdf

Transfer and Expression of Eukaryotic Genes documents the progress in our understanding of the transfer and expression of eukaryotic genes. This book covers topics organized around three themes: gene expression and its regulation; in vivo gene transfer and development; and viral gene and oncogene systems. This text is divided into three sections encompassing 25 chapters and begins with an overview of the molecular basis of gene expression, with emphasis on transcription complexes that account for transcription control in eukaryotic genes. It then turns to experiments that assess the in vitro stimulatory effect of the SV40 72-bp repeat on specific transcription from heterologous promoter elements using a HeLa whole cell extract. The reader is methodically introduced to the regulation signals and factors of histone gene transcription; transcriptional control of beta-globin and liver-specific genes in mouse cells; and gene transfer in Drosophila and the sea urchin Strongylocentrotus purpuratus. This book also considers the splicing of messenger RNA precursors and the regulation of thymidine kinase enzyme expression, and then concludes with a chapter that describes the activation of the myc oncogene by chromosomal translocation. This book will be of interest to students and researchers in fields ranging from molecular genetics to microbiology, biochemistry, pathology, and immunology.

Author : Richard Axel
Publisher : Elsevier
Page : 682 pages
File Size : 54,6 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780323143509

Get Book

Eucaryotic Gene Regulation by Richard Axel Pdf

Eukaryotic Gene Regulation covers the aspects and mechanisms of gene regulation of selected eukaryotes, such as yeast, Drosophila, and insect. This book is organized into eight parts, encompassing 52 chapters. The majority of the chapters are presented in an experimental manner containing an abstract, methods, results and discussion, and conclusion. This book first gives a short overview of the evolutionary role of interspersion in eukaryotic genes. It then presents considerable chapters on control of gene expression in yeast; gene mutation and isolation; structure and function; and analysis. Part III focuses on genetic and DNA sequence analysis in Drosophila. It includes discussions on allelic complementation and transvection, genetic organization, histone gene, and gene transcription. Part IV examines cell lineage; gene expression and sequences; and protein synthesis of insects, sea urchin, and mammalian cells. This is followed by discussions on structure and expression of specific eukaryotic genes from chicken, rat, rabbit, and human. Topics on the transfer of genetic information within and between cells and the structure and function of chromosome are significantly considered in Parts VI and VII. Genes evaluated in these sections include heavy chain immunoglobulin, light chain, beta-globin, and dihydrofolate reductase. Furthermore, this book describes the in vitro transcription and the factors involved; internal organization and mechanism of assembly of nucleosome; and chromatin structure. The concluding section focuses on aspects of viral genome expression including gene regulation, synthesis, processing, and alternative RNA splicing. Research biologists, geneticists, scientists, teachers, and students will greatly benefit from this book.

Author : Gerald M. Kolodny
Publisher : CRC Press
Page : 326 pages
File Size : 42,7 Mb
Release : 2018-01-18
Category : Medical
ISBN : 9781351088831

Get Book

Eukaryotic Gene Regulation by Gerald M. Kolodny Pdf

The cause of cancer and its many manifestations is at present unknown. Since many of its manifestations, including is control of cell division, appear to represent abnormal patterns of gene expression, studies of the regulation of gene expression nwill provide important insights in the understanding and treatment of cancer. This volume attempts to present some of the recent work on regulation of gene expression in eukaryotic cells.

Author : Edgar Wingender
Publisher : Wiley-Blackwell
Page : 452 pages
File Size : 40,9 Mb
Release : 1993
Category : Science
ISBN : UOM:39015029969725

Get Book

Gene Regulation in Eukaryotes by Edgar Wingender Pdf

A much-needed guide through the overwhelming amount of literature in the field. Comprehensive and detailed, this book combines background information with the most recentinsights. It introduces current concepts, emphasizing the transcriptional control of genetic information. Moreover, it links data on the structure of regulatory proteins with basic cellular processes. Both advanced students and experts will find answers to such intriguing questions as: - How are programs of specific gene repertoires activated and controlled? - Which genes drive and control morphogenesis? - Which genes govern tissue-specific tasks? - How do hormones control gene expression in coordinating the activities of different tissues? An abundant number of clearly presented glossary terms facilitates understanding of the biological background. Speacial feature: over 2200 (!) literature references.

Author : David S. Latchman
Publisher : Nelson Thornes
Page : 360 pages
File Size : 42,7 Mb
Release : 1998
Category : Science
ISBN : UOM:39015042395528

Get Book

Gene Regulation by David S. Latchman Pdf

The previous editions of Gene Regulation have helped students in biological science and medicine gain a full understanding of the issues of gene regulation. In this edition, new material reflects the progress that has been made in the understanding of gene regulation. The most significant change is the addition of an extra chapter describing the basic processes by which DNA is converted in RNA and then into protein. This important new chapter makes this edition complete as a textbook on gene expression and its regulation.

Author : Edward J. Murray
Publisher : Springer Science & Business Media
Page : 417 pages
File Size : 51,8 Mb
Release : 2008-02-02
Category : Medical
ISBN : 9781592594948

Get Book

Gene Transfer and Expression Protocols by Edward J. Murray Pdf

Biology is the study of living things. The classical approach might be described as holistic and descriptive, whereas the modern molecular - proach aims to be investigative, reductionist, and mechanistic . Genes contain all the information for the structure of all living things ; thus, the understanding of how genes are regulated is an important step toward understanding the nature of living things. The study of gene regulation has been made more tractable by the design of simple expe- mental models in which a single gene can be isolated from the milieu of the organism. The new science of molecular biology has introduced techniques that permit the design of such experimental models. In - sence, the genome of the organism is dissected in such a manner that specific genes may now be introduced into an appropriate cell line . Subsequent analysis of the proteins expressed from the genes under study results in the identification of the regulatory DNA sequences .

Author : Michael Kriegler
Publisher : Springer
Page : 248 pages
File Size : 45,9 Mb
Release : 1990-06-18
Category : Science
ISBN : 9781349118915

Get Book

Gene Transfer and Expression by Michael Kriegler Pdf

A practical manual of protocols for achieving expression of foreign genes in mammalian cells. It includes some very new techniques such as PCR-based expression. The author gives a theoretical introduction to the protocols and compares the strengths and weaknesses.

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 43,8 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

Get Book

Molecular Biology of The Cell by Bruce Alberts Pdf

Author : Takis S. Papas,Martin J. Rosenberg,Martin Rosenberg,Jack G. Chirikjian
Publisher : Elsevier Publishing Company
Page : 312 pages
File Size : 49,9 Mb
Release : 1983
Category : Cells
ISBN : UCAL:B4456646

Get Book

Expression of Cloned Genes in Prokaryotic and Eukaryotic Cells by Takis S. Papas,Martin J. Rosenberg,Martin Rosenberg,Jack G. Chirikjian Pdf

Author : Lucy W. Barrett,Sue Fletcher,Steve D. Wilton
Publisher : Springer
Page : 56 pages
File Size : 46,5 Mb
Release : 2013-07-09
Category : Science
ISBN : 3034806787

Get Book

Untranslated Gene Regions and Other Non-coding Elements by Lucy W. Barrett,Sue Fletcher,Steve D. Wilton Pdf

There is now compelling evidence that the complexity of higher organisms correlates with the relative amount of non-coding RNA rather than the number of protein-coding genes. Previously dismissed as “junk DNA”, it is the non-coding regions of the genome that are responsible for regulation, facilitating complex temporal and spatial gene expression through the combinatorial effect of numerous mechanisms and interactions working together to fine-tune gene expression. The major regions involved in regulation of a particular gene are the 5’ and 3’ untranslated regions and introns. In addition, pervasive transcription of complex genomes produces a variety of non-coding transcripts that interact with these regions and contribute to regulation. This book discusses recent insights into the regulatory roles of the untranslated gene regions and non-coding RNAs in the control of complex gene expression, as well as the implications of this in terms of organism complexity and evolution.​

Author : Julianne Zedalis,John Eggebrecht
Publisher : Unknown
Page : 1923 pages
File Size : 49,9 Mb
Release : 2017-10-16
Category : Biology
ISBN : 1947172409

Get Book

Biology for AP ® Courses by Julianne Zedalis,John Eggebrecht Pdf

Biology for AP® courses covers the scope and sequence requirements of a typical two-semester Advanced Placement® biology course. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology for AP® Courses was designed to meet and exceed the requirements of the College Board’s AP® Biology framework while allowing significant flexibility for instructors. Each section of the book includes an introduction based on the AP® curriculum and includes rich features that engage students in scientific practice and AP® test preparation; it also highlights careers and research opportunities in biological sciences.

Author : National Research Council,Board on Agriculture
Publisher : National Academies Press
Page : 97 pages
File Size : 51,6 Mb
Release : 1984-02-01
Category : Science
ISBN : 9780309034340

Get Book

Genetic Engineering of Plants by National Research Council,Board on Agriculture Pdf

"The book...is, in fact, a short text on the many practical problems...associated with translating the explosion in basic biotechnological research into the next Green Revolution," explains Economic Botany. The book is "a concise and accurate narrative, that also manages to be interesting and personal...a splendid little book." Biotechnology states, "Because of the clarity with which it is written, this thin volume makes a major contribution to improving public understanding of genetic engineering's potential for enlarging the world's food supply...and can be profitably read by practically anyone interested in application of molecular biology to improvement of productivity in agriculture."

Author : Angus I. Lamond
Publisher : Springer Science & Business Media
Page : 230 pages
File Size : 54,8 Mb
Release : 2013-11-11
Category : Science
ISBN : 9783662223253

Get Book

Pre-mRNA Processing by Angus I. Lamond Pdf

he past fifteen years have seen tremendous growth in our understanding of T the many post-transcriptional processing steps involved in producing func tional eukaryotic mRNA from primary gene transcripts (pre-mRNA). New processing reactions, such as splicing and RNA editing, have been discovered and detailed biochemical and genetic studies continue to yield important new insights into the reaction mechanisms and molecular interactions involved. It is now apparent that regulation of RNA processing plays a significant role in the control of gene expression and development. An increased understanding of RNA processing mechanisms has also proved to be of considerable clinical importance in the pathology of inherited disease and viral infection. This volume seeks to review the rapid progress being made in the study of how mRNA precursors are processed into mRNA and to convey the broad scope of the RNA field and its relevance to other areas of cell biology and medicine. Since one of the major themes of RNA processing is the recognition of specific RNA sequences and structures by protein factors, we begin with reviews of RNA-protein interactions. In chapter 1 David Lilley presents an overview of RNA structure and illustrates how the structural features of RNA molecules are exploited for specific recognition by protein, while in chapter 2 Maurice Swanson discusses the structure and function of the large family of hnRNP proteins that bind to pre-mRNA. The next four chapters focus on pre-mRNA splicing.

Author : Yuan-Chuan Chen,Shiu-Jau Chen
Publisher : BoD – Books on Demand
Page : 212 pages
File Size : 51,9 Mb
Release : 2020-04-01
Category : Science
ISBN : 9781838800314

Get Book

Gene Expression and Phenotypic Traits by Yuan-Chuan Chen,Shiu-Jau Chen Pdf

Gene expression is the most fundamental level at which genotype gives rise to phenotype, which is an obvious, observable, and measurable trait. Phenotype is dependent on genetic makeup of the organism and influenced by environmental conditions. This book explores the significance, mechanism, function, characteristic, determination, and application of gene expression and phenotypic traits.

Author : Thomas Robert Russell
Publisher : Unknown
Page : 682 pages
File Size : 54,9 Mb
Release : 1979
Category : Science
ISBN : UOM:39015006001666

Get Book

From Gene to Protein by Thomas Robert Russell Pdf

From Gene to Protein: Information Transfer in Normal and Abnormal Cells ...