Translational Autoimmunity Volume 3

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Translational Autoimmunity, Volume 3

Nima Rezaei
Translational Autoimmunity Volume 3 Book PDF

Author : Nima Rezaei
Publisher : Academic Press
Page : 404 pages
File Size : 53,5 Mb
Release : 2022-04-01
Category : Medical
ISBN : 9780323854160

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Translational Autoimmunity, Volume 3 by Nima Rezaei Pdf

Translational Autoimmunity: Autoimmune Diseases in Different Clinical Settings addresses autoimmunity and associated conditions, such as aging, infectious diseases, cancer, neurodegeneration, psychological disorders, fertility, inflammatory vascular diseases, and interstitial lung diseases. The book addresses sufficiently basic questions on how the immune system is designed to distinguish self from no self and behave such that it's able to maintain self-tolerance, how does it work in infections, and how it elicits an auto-reactive state and develops self-antigens seen in autoimmune conditions. This is followed by an overview on the genetic and clinical aspects of the spectrum of autoimmune diseases which are broadly categorized into two types of organ specific autoimmune diseases and non-organ specific autoimmune diseases (also known as systemic autoimmune diseases). Covers clinical aspects of autoimmunity and translational immunology studies in autoimmunity in different clinical settings Meets the needs of basic scientists, clinicians, translational scientists and industry partners Supported by a systematic appraisal of the most recent evidence

Translational Autoimmunity, Volume 1

Nima Rezaei
Translational Autoimmunity Volume 1 Book PDF

Author : Nima Rezaei
Publisher : Academic Press
Page : 392 pages
File Size : 40,5 Mb
Release : 2021-10-22
Category : Medical
ISBN : 9780128232774

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Translational Autoimmunity, Volume 1 by Nima Rezaei Pdf

Translational Autoimmunity: Etiology of Autoimmune Diseases is the first volume of the Translational Immunology book series. To attain its purpose as a detailed translational step to tackle autoimmunity, this volume sufficiently addresses basic questions on how the immune system is designed to distinguish self from nonself. It discusses the known mechanisms that lead to the maintenance of self-tolerance, presents potential triggers and malfunctions that impede normal immune processes, and demonstrates how the immune system induces an autoreactive state that results in the recognition of self-antigens seen in autoimmune conditions. Includes coverage of basic immunology, the clinical aspects of autoimmunity, and translational immunology studies in autoimmunity Presents key concepts supported by a systematic appraisal of the most recent evidence Assists students at all the academic levels while also being applicable to scientists who work with autoimmunity Designed for learning, teaching, review, testing, practice and research

Translational Autoimmunity, Volume 4

Nima Rezaei
Translational Autoimmunity Volume 4 Book PDF

Author : Nima Rezaei
Publisher : Academic Press
Page : 460 pages
File Size : 43,9 Mb
Release : 2022-05-01
Category : Medical
ISBN : 9780323859769

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Translational Autoimmunity, Volume 4 by Nima Rezaei Pdf

As the autoimmune diseases could affect different organs, Translational Autoimmunity: Autoimmune Diseases in Different Organs addresses the spectrum of autoimmune diseases. The fourth volume of Translational Immunology Series focuses on clinical and laboratory details of autoimmune diseases which are broadly categorized into two types of organ-specific autoimmune diseases and non-organ specific autoimmune diseases (also known as systemic autoimmune diseases). Autoimmune rheumatic diseases such as systemic lupus erythematosus and rheumatoid arthritis, autoimmune rheumatic diseases such as diabetes mellitus and thyroid diseases, autoimmune neurologic diseases such as multiple sclerosis, as well as autoimmune hepatobiliary diseases, autoimmune renal diseases and autoimmune cutaneous diseases as the subject of discussion in Translational Autoimmunity: Autoimmune Diseases in Different Organs. Comprises major parts that cover basic immunology, clinical aspects of autoimmunity, and translational immunology studies in autoimmunity Each and every key concept will be mentioned after an easy background is drawn and then, will be supported by a systematic appraisal of the most recent evidence Can help students at all the academic levels while applicable to scientists who work with autoimmunity Designed for learning, teaching, review and testing, practice, and research. Hence, it might be useful for students, teachers and instructors, physicians, and researchers

Translational Autoimmunity, Volume 2

Nima Rezaei
Translational Autoimmunity Volume 2 Book PDF

Author : Nima Rezaei
Publisher : Academic Press
Page : 488 pages
File Size : 48,8 Mb
Release : 2022-01-05
Category : Medical
ISBN : 9780323859752

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Translational Autoimmunity, Volume 2 by Nima Rezaei Pdf

Translational Autoimmunity: Treatment of Autoimmune Diseases, Volume Two in the Translational Immunology series, focuses on advances in therapeutic modalities in autoimmune diseases. Efficacy and safety of not only the current biologic therapies, but also novel drug targets are discussed. Therapeutic targeting of B regulatory cells, T regulatory cells, as well as the immunomodulation effects of nanoparticles and organisms are also covered, along with our understanding and future challenges of prognostic significance of treatments in autoimmune diseases. Covers the clinical aspects and treatment of autoimmunite diseases Meets the needs of basic scientists, clinicians and translational scientists and industry partners Mentions each and every key concept after background is drawn Supported by a systematic appraisal of the most recent evidence Helps students at all academic levels, but is also applicable to scientists who work with autoimmunity

Translational Autoimmunity, Volume 6

Nima Rezaei
Translational Autoimmunity Volume 6 Book PDF

Author : Nima Rezaei
Publisher : Elsevier
Page : 630 pages
File Size : 40,6 Mb
Release : 2023-02-20
Category : Medical
ISBN : 9780323984546

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Translational Autoimmunity, Volume 6 by Nima Rezaei Pdf

Translational Autoimmunity: Advances in Autoimmune Rheumatic Diseases, Volume Six addresses autoimmune diseases classified under the category of rheumatic diseases. Rheumatic diseases are heterogeneous groups of disorders in which inflammation affects not only joints, but also tendons, ligaments and bones. This updated release focuses on immunopathogenesis and clinical and laboratory details of rheumatic diseases, including rheumatoid arthritis, systemic lupus erythematosus, psoriatic arthritis, osteoarthritis and Sjogren’s syndrome, and will be of interest to researchers, students and clinicians interested in autoimmune diseases, especially rheumatic diseases. From an introduction to rheumatic diseases to diagnostic laboratory tests, and from the microbiota-immunity to cell-based therapies, the bench to bedside approach to rheumatic diseases is the main subject of discussion in this comprehensive resource. Gives an introduction on rheumatic diseases, from bench to bedside Describes diagnostic laboratory tests in rheumatic diseases Meets the needs of basic scientists, clinicians and translational scientists and industry partners Focuses on immunopathogenesis and clinical and laboratory details of rheumatic diseases

Translational Autoimmunity, Volume 5

Nima Rezaei
Translational Autoimmunity Volume 5 Book PDF

Author : Nima Rezaei
Publisher : Elsevier
Page : 420 pages
File Size : 53,9 Mb
Release : 2022-09-13
Category : Medical
ISBN : 9780323853903

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Translational Autoimmunity, Volume 5 by Nima Rezaei Pdf

Translational Autoimmunity: Challenges for Autoimmune Diseases, Fifth Edition addresses diagnostic approaches, therapeutic opportunities, and prognostic markers of different autoimmune diseases. This updated volume discusses autotoxicity, systems immunology, the prognostic significance of disease-specific autoantibodies, along with translational research to novel therapeutic policy in autoimmune diseases. From an introduction, to challenges and insights on the systems immunology of infectious and autoimmune diseases, new targets of treatments, and the role of autoantibodies in diagnosis and evolution, this book provides insights on many challenges researchers and clinicians are facing. Describes challenges in the diagnosis, management and treatment of autoimmune diseases Highlights major difficulties in the diagnosis and management of autoimmune diseases Reflects important remediable deficiencies in current management Meets the needs of basic scientists, clinicians and translational scientists and industry partners

Translational Inflammation

Anonim
Translational Inflammation Book PDF

Author : Anonim
Publisher : Academic Press
Page : 294 pages
File Size : 48,9 Mb
Release : 2018-11-24
Category : Medical
ISBN : 9780128138335

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Translational Inflammation by Anonim Pdf

Translational Inflammation links laboratory and clinical data within primary and secondary care to clinical research data and offers a holistic and innovative approach to chronic inflammation and ageing. Understanding the role of inflammation as a part of clinical disease states is becoming a valuable tool in both direct treatment and the development of therapeutics. Translational Inflammation, the 4th volume in the Perspectives in Translational Cell Biology series, offers content for professors, students and researchers across basic and translational biology. Emphasizes the role of inflammation in disease and therapeutic approaches Integrates broad concepts relating inflammation to other fields Offers a bridge to review literature and primary research on the inflammatory response towards medical application

Immunogenetics: A Molecular and Clinical Overview

Muneeb U. Rehman,Azher Arafah,Md. Niamat Ali,Shafat Ali
Immunogenetics A Molecular and Clinical Overview Book PDF

Author : Muneeb U. Rehman,Azher Arafah,Md. Niamat Ali,Shafat Ali
Publisher : Academic Press
Page : 412 pages
File Size : 41,5 Mb
Release : 2021-11-30
Category : Medical
ISBN : 9780323903356

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Immunogenetics: A Molecular and Clinical Overview by Muneeb U. Rehman,Azher Arafah,Md. Niamat Ali,Shafat Ali Pdf

A Molecular Approach to Immunogenetics, Immunogenetics: A Molecular and Clinical Overview, Volume One provides readers with an exclusive, updated overview on the scientific knowledge, achievements and findings in the field of immunogenetics. The book presents readily available, updated information on the molecular and clinical aspects of immunogenetics, from origin and development to clinical applications and future prospects. The breadth of information goes from basics to developments, clinical applications and future prospects. The book's most attractive attribute is its academic and clinical amalgamation that covers both the theoretical and practical aspects of immunogenetics. An additional feature of the book is a special chapter on viral genetics that covers COVID-19. Above all, the book contains chapters that discuss immunogenetics in relation to pharmaco-genomics and immune-toxicology. Contains exclusive information about research on immunogenetics from around the globe Includes minute and recent details that will be the prerequisite requirement for any researcher who wants to work on immunogenetics and its applications Comes fully-equipped with pictures, illustrations and tables that deliver information in a meticulous manner

Mosaic of Autoimmunity

Carlo Perricone,Yehuda Shoenfeld
Mosaic of Autoimmunity Book PDF

Author : Carlo Perricone,Yehuda Shoenfeld
Publisher : Academic Press
Page : 728 pages
File Size : 53,5 Mb
Release : 2019-02-15
Category : Medical
ISBN : 9780128143070

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Mosaic of Autoimmunity by Carlo Perricone,Yehuda Shoenfeld Pdf

The Mosaic of Autoimmunity: The Novel Factors of Autoimmune Diseases describes the multifactorial origin and diversity of expression of autoimmune diseases in humans. The term implies that different combinations of factors in autoimmunity produce varying and unique clinical pictures in a wide spectrum of autoimmune diseases. Most of the factors involved in autoimmunity can be categorized into four groups: genetic, immune defects, hormonal and environmental factors. In this book, the environmental factors are reviewed, including infectious agents, vaccines as triggers of autoimmunity, smoking and its relationship with rheumatoid arthritis, systemic lupus erythematosus, thyroid disease, multiple sclerosis and inflammatory bowel diseases. An entirely new syndrome, the autoimmune/inflammatory syndrome induced by adjuvants (ASIA), is also included, along with other diseases that are now recognized as having an autoimmune etiopathogenesis. Highlights the concept of the mosaic of autoimmune manifestations Includes new visions on unsuspected molecules Provides updated knowledge to physicians helping patients with autoimmune diseases Presents thorough, up-to-date information on specific diseases, along with clinical applications

Autoimmune Neurology

Anonim
Autoimmune Neurology Book PDF

Author : Anonim
Publisher : Elsevier
Page : 568 pages
File Size : 44,7 Mb
Release : 2016-03-11
Category : Science
ISBN : 9780444634467

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Autoimmune Neurology by Anonim Pdf

Autoimmune Neurology presents the latest information on autoimmune neurologic disease, the immune response to the body where organs run wild, causing the immune system to attack itself. Autoimmunity is a main element in numerous nervous system diseases and can target any structure within the central or peripheral nervous system. Over the past 20 years, significant advances in our understanding of the pathophysiology of autoimmune disorders, including the use of biomarkers has led to new diagnosis and treatment options. Neurologic conditions associated with autoimmune reactions include dementia, neuromuscular disease, epilepsy, sleep disorders, diabetes, and other common neurologic disorders and disease. This current tutorial-reference will be a must-have title for clinical neurologists, research neurologists, neuroscientists, and any medical professional working with autoimmune disease and disorders. Includes comprehensive coverage of autoimmune neurology Details the latest techniques for the study, diagnosis, and treatment of diseases and disorders, including dementia, neuromuscular disease, epilepsy, and sleep disorders Presents a focused reference for clinical practitioners and the clinical neurology and neurology research communities

Translational Methods for Multiple Sclerosis Research

Sergiu Groppa,Sven G. Meuth
Translational Methods for Multiple Sclerosis Research Book PDF

Author : Sergiu Groppa,Sven G. Meuth
Publisher : Humana
Page : 335 pages
File Size : 55,9 Mb
Release : 2021-08-03
Category : Medical
ISBN : 1071612123

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Translational Methods for Multiple Sclerosis Research by Sergiu Groppa,Sven G. Meuth Pdf

This volume explores the recent advances in the study of translational paths in central inflammation and focuses on ongoing pathophysiological processes and the transition between inflammatory stages and progressive states with neurodegeneration. Chapters cover topics such as pathophysiological hallmarks of neuroinflammation from tissue damage to reorganization; connecting studies of mouse models; and investigations of humans with multiple sclerosis. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and practical, Translational Methods for Multiple Sclerosis Research is a valuable resource for researchers who want to learn more about this chronic ad progressive disease, and pave the way for new advancements.

Regulatory T Cells in Health and Disease

Anonim
Regulatory T Cells in Health and Disease Book PDF

Author : Anonim
Publisher : Academic Press
Page : 300 pages
File Size : 41,6 Mb
Release : 2015-11-26
Category : Medical
ISBN : 9780128034194

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Regulatory T Cells in Health and Disease by Anonim Pdf

Regulatory T Cells in Health and Disease focuses on the mechanism by which T cells become regulatory T cells, the processes which control the number of regulatory T cells in the blood and tissue, and the ways in which regulatory T cell prevent autoimmune disease and interact with infections and cancer. Contains contributions from leading authorities in the field of regulatory T cell biology Informs and updates on all the latest developments in the field Explores the processes which control the number of regulatory T cells in the blood and tissue, and the ways in which regulatory T cell prevent autoimmune disease and interact with infections and cancer

Precision Medicine

David B. Teplow
Precision Medicine Book PDF

Author : David B. Teplow
Publisher : Academic Press
Page : 298 pages
File Size : 40,8 Mb
Release : 2022-08-23
Category : Science
ISBN : 9780323997850

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Precision Medicine by David B. Teplow Pdf

Precision Medicine, Volume 190 in the Progress in Molecular Biology and Translational Science series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Evolution of Biomarkers and Strategies for Integrating the Precision Philosophy to Guide Monitoring of Individualized Autoimmunity Conditions and to Implement the Philosophy into Clinical Practice, Precision Medicine in Epilepsy, The use of ASOs for personized medicine, Adult medicine, EGFR, NF-KB signal and regulatory noncoding RNAs in cancer, Precision medicine with multi-omics strategies, deep phenotyping, and predictive analysis, The Paradox of Personalized Medicine, and more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Progress in Molecular Biology and Translational Science series Updated release includes the latest information on the precision medicine

Pathogenesis of Systemic Lupus Erythematosus

Alberta Hoi
Pathogenesis of Systemic Lupus Erythematosus Book PDF

Author : Alberta Hoi
Publisher : Springer Nature
Page : 192 pages
File Size : 50,8 Mb
Release : 2021-11-15
Category : Medical
ISBN : 9783030851613

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Pathogenesis of Systemic Lupus Erythematosus by Alberta Hoi Pdf

The scope of this contributed volume is to provide an overview of the latest translational research in the field of lupus pathogenesis, with particular emphasis on how these discoveries progress in parallel with therapeutic drug development. Systemic lupus erythematosus (SLE) is a multifaceted disease with a number of well-defined immune pathways that are dysregulated, resulting in an immune-mediated chronic inflammatory injury at target organs. As knowledge of these pathways evolves to provide opportunities for targeted drug therapy and lays the foundation for personalized medicine, clinicians and researchers need to keep up with the ever-expanding medical literature. This book will critically appraise the current understanding of important immunological pathways that contribute to the pathogenesis of lupus. We will review the role of interferons as part of the innate immune defects that perpetuate the loss of self-tolerance in SLE. B cell hyperactivity, as a defining hallmark of SLE, and different strategies of B cell targeted therapy will be discussed. The role of co-stimulation or immune checkpoint molecules in activating B and T cells will be reviewed, as well as other cytokines that serve in the amplification loop promoting a more proinflammatory Th1 or Th17 responses. Intracellular targets, such as signaling molecules in the JAK/STAT pathway, or a variety of kinases and proteasomes, can cause a cascading downstream effect of transcriptional responses that are important in SLE. Immune homeostasis can also be restored by bolstering the naturally occurring anti-inflammatory mechanisms. Glucocorticoid, as a potent natural anti-inflammatory hormone, can mediate its effects by recruiting histone deacetylase that serve to repress gene transcription. Glucocorticoid-induced leucine zipper is a gene upregulated by glucocorticoid that can be a potential target for development of anti-inflammatory strategy. Finally, T regulatory cells can be utilized to help restore to immune tolerance and are amongst the latest focus of therapeutic development in SLE.

Reproductive Immunology

Gil Mor
Reproductive Immunology Book PDF

Author : Gil Mor
Publisher : Academic Press
Page : 462 pages
File Size : 54,6 Mb
Release : 2021-02-12
Category : Medical
ISBN : 9780128189306

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Reproductive Immunology by Gil Mor Pdf

Reproductive Immunology: Basic Concepts gives a holistic insight into the understanding of the complex interactions between the maternal immune system and the fetal/placental unit necessary for the success of pregnancy. This interaction is critical for the support of the human fetal semiallograft and the protection against infections. The book covers various topics such as B cells, macrophages, T cells, discussion on fetal signals and their impact on maternal reproductive cells such as endometrial cells, mast cells, and the role of fetal Hofbauer cells, the immune regulatory role of glucorticoids, and many other novel topics within the field of reproductive immunology. Edited and written by experts in the field, this book introduces the up-to-date knowledge of the role of the immune system during pregnancy and provides the necessary background to understand pregnancy complications associated with alterations in the functioning of the immune system. The book provides a complete discussion on the immunological aspects of pregnancy and serves as a great tool for research scientists, students, reproductive immunologists and OBGYNs. Shows the detailed evaluation of the knowledge related to each immune cell type in the pregnant and not pregnant uterus Evaluates each immune cell type and its function during specific reproductive events Provides the biological background for understanding the clinical aspects that will be discussed in subsequent volumes in the series