Translational Biotechnology

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CRISPR-Cas System in Translational Biotechnology

Swati Joshi,Digvijay Verma,Ravi Kr. Gupta
CRISPR Cas System in Translational Biotechnology Book PDF

Author : Swati Joshi,Digvijay Verma,Ravi Kr. Gupta
Publisher : Elsevier
Page : 317 pages
File Size : 47,7 Mb
Release : 2023-12-01
Category : Science
ISBN : 9780323972284

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CRISPR-Cas System in Translational Biotechnology by Swati Joshi,Digvijay Verma,Ravi Kr. Gupta Pdf

CRISPR-Cas System in Translational Biotechnology discusses applied and translational aspects of the CRISPR-Cas technology. The book bridges the gap between theoretical knowledge and practical solutions surrounding this emerging and impactful technology in several academic and industrial fields. It is split in five sections: CRISP-Cas fundamentals and advancements; CRISP-Cas in medical biotechnology; CRISP-Cas in environmental biotechnology; CRISP-Cas in food biotechnology; and biosafety, patents and commercialization of CRISP-Cas technology. Written by experts from diverse backgrounds, the content covers the subject and its impact in multiple fields. It is a valuable resource for graduate students and researchers on bioinformatics, systems biology, and members of the biomedical field and biotechnology industry who are interested in learning more about CRISP-Cas system and its applications. Discusses applied aspects of CRISPR-Cas technology and state-of-the-art technological/translational advancements in the field Focuses on the CRISPR-Cas mediated genetic engineering for employment in various industries such as medical, agricultural, environmental and food Encompasses knowledge on CRISPR-Cas commercialization, potential markets and associated ethical challenges

Translational Biotechnology

Yasha Hasija
Translational Biotechnology Book PDF

Author : Yasha Hasija
Publisher : Academic Press
Page : 453 pages
File Size : 50,7 Mb
Release : 2021-01-17
Category : Medical
ISBN : 9780128219737

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Translational Biotechnology by Yasha Hasija Pdf

Translational Biotechnology: A Journey from Laboratory to Clinics presents an integrative and multidisciplinary approach to biotechnology to help readers bridge the gaps between fundamental and functional research. The book provides state-of-the-art and integrative views of translational biotechnology by covering topics from basic concepts to novel methodologies. Topics discussed include biotechnology-based therapeutics, pathway and target discovery, biological therapeutic modalities, translational bioinformatics, and system and synthetic biology. Additional sections cover drug discovery, precision medicine and the socioeconomic impact of translational biotechnology. This book is valuable for bioinformaticians, biotechnologists, and members of the biomedical field who are interested in learning more about this promising field. Explains biotechnology in a different light by using an application-oriented approach Discusses practical approaches in the development of precision medicine tools, systems and dynamical medicine approaches Promotes research in the field of biotechnology that is translational in nature, cost-effective and readily available to the community

The Market in Mind

Mark Dennis Robinson
The Market in Mind Book PDF

Author : Mark Dennis Robinson
Publisher : MIT Press
Page : 325 pages
File Size : 42,7 Mb
Release : 2019-07-23
Category : Science
ISBN : 9780262536875

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The Market in Mind by Mark Dennis Robinson Pdf

A critical examination of translational medicine, when private risk is transferred to the public sector and university research teams become tech startups for global investors. A global shift has secretly transformed science and medicine. Starting in 2003, biomedical research in the West has been reshaped by the emergence of translational science and medicine—the idea that the aim of research is to translate findings as quickly as possible into medical products. In The Market in Mind, Mark Dennis Robinson charts this shift, arguing that the new research paradigm has turned university research teams into small biotechnology startups and their industry partners into early-stage investment firms. There is also a larger, surprising consequence from this shift: according to Robinson, translational science and medicine enable biopharmaceutical firms, as part of a broader financial strategy, to outsource the riskiest parts of research to nonprofit universities. Robinson examines the implications of this new configuration. What happens, for example, when universities absorb unknown levels of risk? Robinson argues that in the years since the global financial crisis translational science and medicine has brought about “the financialization of health.” Robinson explores such topics as shareholder anxiety and industry retreat from Alzheimer's and depression research; how laboratory research is understood as health innovation even when there is no product; the emergence of investor networking events as crucial for viewing science in a market context; and the place of patients in research decisions. Although translational medicine justifies itself by the goal of relieving patients' suffering, Robinson finds patients' voices largely marginalized in translational neuroscience.

Biotechnology Entrepreneurship

Craig Shimasaki
Biotechnology Entrepreneurship Book PDF

Author : Craig Shimasaki
Publisher : Academic Press
Page : 684 pages
File Size : 51,5 Mb
Release : 2020-05-16
Category : Reference
ISBN : 9780128155868

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Biotechnology Entrepreneurship by Craig Shimasaki Pdf

This second edition of Biotechnology Entrepreneurship: Leading, Managing, and Commercializing Innovative Technologies is an authoritative, easy-to-read guide covering biotechnology entrepreneurship and the process of commercializing innovative biotechnology products. This best practice resource is for professional training programs, individuals starting a biotech venture, and for managers and experienced practitioners leading biotech enterprises. It is a valuable resource for those working at any level in the biotech industry, and for professionals who support and provide essential resources and services to the biotech industry. This practical, “how-to book is written by seasoned veterans experienced in each of the operational functions essential for starting, managing, and leading a successful biotech company.Biotechnology Entrepreneurship explains the biotech business components and underlying strategies, interspersed with practical lessons from successful biotech entrepreneurs, educators, and experienced practitioners. These veteran contributors share their insights on how to be successful in this challenging but exciting industry. Subjects range from technology licensing and translating an idea into a viable business, forming your legal company entity, securing angel and venture capital, navigating product development, FDA regulatory approval, and biomanufacturing.This book is a user-friendly guide to decision-making and overall strategy written as a hands-on management tool for leaders and managers of these dynamic biotechnology ventures. If you are contemplating starting a biotech company, are a manager at any level, a seasoned veteran, or service provider in the biotech industry, this book is a “must read. This second edition includes several new chapters on topics such as: What you need to know about valuation and term sheets Investor presentations and what you need in a biotech investor pitch deck Mentorship and why you need mentors Artificial intelligence applications in biotech and pharma Common biotech entrepreneur mistakes and how to avoid them

Translational Medicine and Drug Discovery

Bruce H. Littman,Rajesh Krishna
Translational Medicine and Drug Discovery Book PDF

Author : Bruce H. Littman,Rajesh Krishna
Publisher : Cambridge University Press
Page : 385 pages
File Size : 44,7 Mb
Release : 2011-01-31
Category : Medical
ISBN : 9781139498722

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Translational Medicine and Drug Discovery by Bruce H. Littman,Rajesh Krishna Pdf

This book focuses on the new discipline of translational medicine as it pertains to drug development within the pharmaceutical and biotechnology industry. It is essential for anyone interested in translational medicine from a variety of backgrounds: university institutes, medical schools, pharmaceutical companies and drug development researchers and decision-makers.

Animal Biotechnology

Ashish Verma,Anchal Singh
Animal Biotechnology Book PDF

Author : Ashish Verma,Anchal Singh
Publisher : Academic Press
Page : 668 pages
File Size : 52,8 Mb
Release : 2013-11-04
Category : Science
ISBN : 9780123914347

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Animal Biotechnology by Ashish Verma,Anchal Singh Pdf

Animal Biotechnology introduces applications of animal biotechnology and implications for human health and welfare. It begins with an introduction to animal cell cultures and genome sequencing analysis and provides readers with a review of available cell and molecular tools. Topics here include the use of transgenic animal models, tissue engineering, nanobiotechnology, and proteomics. The book then delivers in-depth examples of applications in human health and prospects for the future, including cytogenetics and molecular genetics, xenografts, and treatment of HIV and cancers. All this is complemented by a discussion of the ethical and safety considerations in the field. Animal biotechnology is a broad field encompassing the polarities of fundamental and applied research, including molecular modeling, gene manipulation, development of diagnostics and vaccines, and manipulation of tissue. Given the tools that are currently available and the translational potential for these studies, animal biotechnology has become one of the most essential subjects for those studying life sciences. Highlights the latest biomedical applications of genetically modified and cloned animals with a focus on cancer and infectious diseases Provides firsthand accounts of the use of biotechnology tools, including molecular markers, stem cells, and tissue engineering

Translational Biology in Medicine

M. Montano
Translational Biology in Medicine Book PDF

Author : M. Montano
Publisher : Elsevier
Page : 228 pages
File Size : 44,9 Mb
Release : 2014-12-08
Category : Science
ISBN : 9781908818652

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Translational Biology in Medicine by M. Montano Pdf

The recent emphasis in biomedical research on translational biology and personalized medicine is revolutionizing conceptual and experimental approaches to understanding and improving human health. Translational Biology in Medicine begins with an introduction to experimental model systems for disease, such as cell lines, primary cells, stem cells and animal models for disease, followed by a systematic description of genetic and genomic profiling and biomarker validation currently used in biomedical research. Examples of translation studies that have used these models and methods are presented, including studies in aging, tissue repair and chronic infection, each with an emphasis on how personalized medicine is transforming biomedicine. Bioethical considerations in translational study design and bioethical considerations in biomedical research are then covered, before concluding remarks, and a look towards the future of personalized medicine. Describes cellular and animal model systems used in translational research Discusses the use of blood, genetic and genomic biomarkers for disease Presents translational studies in aging, tissue repair and infectious disease biomedicine

Cell Biology and Translational Medicine, Volume 2

Kursad Turksen
Cell Biology and Translational Medicine Volume 2 Book PDF

Author : Kursad Turksen
Publisher : Springer
Page : 155 pages
File Size : 52,9 Mb
Release : 2018-11-28
Category : Science
ISBN : 9783030041700

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Cell Biology and Translational Medicine, Volume 2 by Kursad Turksen Pdf

Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This online first book series 'Cell Biology and Translational Medicine (CBTMED)' as part of SpringerNature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the second volume of a continuing series.

Handbook of translational medicine

Josep M. Llovet
Handbook of translational medicine Book PDF

Author : Josep M. Llovet
Publisher : Edicions Universitat Barcelona
Page : 245 pages
File Size : 52,9 Mb
Release : 2016-10-05
Category : Medical
ISBN : 9788447540303

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Handbook of translational medicine by Josep M. Llovet Pdf

This handbook aims to capture the basic concepts of translational medicine, understood as a branch of the biomedical field that translates discoveries into the clinical setting. This discipline is currently closing the gap between basic science and clinical research. The book is intended to be straightforward, easy-to-read, intelligible and practical. It describes the basic principles of translational medicine, including major advances in genomics, new technologies, the processing of big data and biobanks. Regarding the biological foundations of translational medicine, we address concepts related to the molecular basis of cancer, inflammation, angiogenesis, stem cells and experimental models. More specifically on translational medicine, we present discoveries and breakthroughs in oncology, neuroscience, metabolic and systemic diseases, and public health. Finally, we have specific sections focused on clinical trials and biomarkers in the genomic era, advances in imaging techniques and entrepreneurship and innovation. Our purpose is to offer a manageable text to guide graduate and post-graduate students, professionals and researchers in biomedicine through the major technologies and advances that have occurred in the translational field. It is also intended to aid residents, fellows and physician-scientists working in hospitals and academic institutions.

Animal Biotechnology

Ashish S. Verma,Anchal Singh
Animal Biotechnology Book PDF

Author : Ashish S. Verma,Anchal Singh
Publisher : Academic Press
Page : 799 pages
File Size : 42,8 Mb
Release : 2020-06-11
Category : Medical
ISBN : 9780128117255

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Animal Biotechnology by Ashish S. Verma,Anchal Singh Pdf

Animal Biotechnology: Models in Discovery and Translation, Second Edition, provides a helpful guide to anyone seeking a thorough review of animal biotechnology and its application to human disease and welfare. This updated edition covers vital fundamentals, including animal cell cultures, genome sequencing analysis, epigenetics and animal models, gene expression, and ethics and safety concerns, along with in-depth examples of implications for human health and prospects for the future. New chapters cover animal biotechnology as applied to various disease types and research areas, including in vitro fertilization, human embryonic stem cell research, biosensors, enteric diseases, biopharming, organ transplantation, tuberculosis, neurodegenerative disorders, and more. Highlights the latest biomedical applications of genetically modified and cloned animals, with a focus on cancer and infectious diseases Offers first-hand accounts of the use of biotechnology tools, including molecular markers, stem cells, animal cultures, tissue engineering, ADME and CAM Assay Includes case studies that illustrate safety assessment issues, ethical considerations, and intellectual property rights associated with the translation of animal biotechnology studies

Information Retrieval in Bioinformatics

Soumi Dutta,Saikat Gochhait
Information Retrieval in Bioinformatics Book PDF

Author : Soumi Dutta,Saikat Gochhait
Publisher : Springer Nature
Page : 167 pages
File Size : 55,5 Mb
Release : 2022-12-01
Category : Computers
ISBN : 9789811965067

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Information Retrieval in Bioinformatics by Soumi Dutta,Saikat Gochhait Pdf

The book presents the results of studies on selected problems (such as predictive model of transcription initiation and termination, protein recognition codes, protein structure prediction, feature selection for disease prediction, information retrieval from medical imaging) of Bioinformatics and Information Retrieval. Information Retrieval is one of the contemporary answers to new challenges in threat evaluation of composite systems. This book provides a practical course in computational data analysis suitable for students or researchers with no previous exposure to computer programming. It describes in detail the theoretical basis for statistical analysis techniques used throughout the textbook, from basic principles. It presents walk-throughs of data analysis tasks using different tools to help in taking decisions in healthcare management.

Animal Biotechnology

Ashish S. Verma,Anchal Singh
Animal Biotechnology Book PDF

Author : Ashish S. Verma,Anchal Singh
Publisher : Academic Press
Page : 798 pages
File Size : 48,8 Mb
Release : 2020-06-23
Category : Medical
ISBN : 9780128117101

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Animal Biotechnology by Ashish S. Verma,Anchal Singh Pdf

Animal Biotechnology: Models in Discovery and Translation, Second Edition, provides a helpful guide to anyone seeking a thorough review of animal biotechnology and its application to human disease and welfare. This updated edition covers vital fundamentals, including animal cell cultures, genome sequencing analysis, epigenetics and animal models, gene expression, and ethics and safety concerns, along with in-depth examples of implications for human health and prospects for the future. New chapters cover animal biotechnology as applied to various disease types and research areas, including in vitro fertilization, human embryonic stem cell research, biosensors, enteric diseases, biopharming, organ transplantation, tuberculosis, neurodegenerative disorders, and more. Highlights the latest biomedical applications of genetically modified and cloned animals, with a focus on cancer and infectious diseases Offers first-hand accounts of the use of biotechnology tools, including molecular markers, stem cells, animal cultures, tissue engineering, ADME and CAM Assay Includes case studies that illustrate safety assessment issues, ethical considerations, and intellectual property rights associated with the translation of animal biotechnology studies

From Gene to Protein: Translation into Biotechnology

Fazal Ahmad
From Gene to Protein Translation into Biotechnology Book PDF

Author : Fazal Ahmad
Publisher : Elsevier
Page : 612 pages
File Size : 51,9 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780323144612

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From Gene to Protein: Translation into Biotechnology by Fazal Ahmad Pdf

From Gene to Protein: Translation into Biotechnology is the 15th volume in the continuing series under the title ""Miami Winter Symposia"". The theme of the symposium is the translation of the basic research findings into the practical application of biotechnology. This book summarizes methodology and its applications that lie behind the practical innovations. The book starts with reviews of techniques of eukaryotic cell culture, hybridoma technology and uses, and the in vitro synthesis of DNA and its use in the generation of protein analogs. Considerable space is devoted to development of monoclonal antibodies that promises to be the dominating tool of medical technology, both for diagnosis and therapy. Cloning into eukaryotic cells and methods of increasing the levels of gene expression are included. These topics reflect areas of intensive research that have important commercial and clinical value. Core chapters describe biological activities of cloned gene products, including reports on trials with human subjects of interferon, human insulin, and growth hormone. A panel session on horizons in biotechnology is also provided, looking forward to the directions of future research and its applications. Biotechnologists, cell biologists, scientists, researchers, teachers, and students will greatly benefit from this book.

Patenting the Recombinant Products of Biotechnology and Other Molecules

Phillipe Ducor
Patenting the Recombinant Products of Biotechnology and Other Molecules Book PDF

Author : Phillipe Ducor
Publisher : Kluwer Law International B.V.
Page : 200 pages
File Size : 55,8 Mb
Release : 1998-06-19
Category : Law
ISBN : 9789041106988

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Patenting the Recombinant Products of Biotechnology and Other Molecules by Phillipe Ducor Pdf

The avenue consisting in lowering the non obviousness standard, chosen by the Federal Circuit in In re Deuel, is rejected in a detailed critic of the case. Several current examples of sui generis intellectual property rights are then described. A "no action" scenario is also examined, emphasizing that the rapid changes occurring in biotechnology might ultimately make the current problem obsolete. Finally, broader issues such as the growing secrecy in basic science are acknowledged, and linked to the disappearance of a clear distinction between basic and applied research.

Comprehensive Biotechnology

Anonim
Comprehensive Biotechnology Book PDF

Author : Anonim
Publisher : Elsevier
Page : 4876 pages
File Size : 52,8 Mb
Release : 2019-07-17
Category : Science
ISBN : 9780444640475

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Comprehensive Biotechnology by Anonim Pdf

Comprehensive Biotechnology, Third Edition, Six Volume Set unifies, in a single source, a huge amount of information in this growing field. The book covers scientific fundamentals, along with engineering considerations and applications in industry, agriculture, medicine, the environment and socio-economics, including the related government regulatory overviews. This new edition builds on the solid basis provided by previous editions, incorporating all recent advances in the field since the second edition was published in 2011. Offers researchers a one-stop shop for information on the subject of biotechnology Provides in-depth treatment of relevant topics from recognized authorities, including the contributions of a Nobel laureate Presents the perspective of researchers in different fields, such as biochemistry, agriculture, engineering, biomedicine and environmental science