Translational Cardiology

Author : Cam Patterson,Monte S. Willis
Publisher : Springer Science & Business Media
Page : 556 pages
File Size : 40,8 Mb
Release : 2012-07-04
Category : Medical
ISBN : 9781617798917

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Translational Cardiology by Cam Patterson,Monte S. Willis Pdf

Translational Cardiology: Molecular Basis of Cardiac Metabolism, Cardiac Remodeling, Translational Therapies and Imaging Techniques provides an up-to-date introduction to the role circadian rhythms, cardiac plasticity, and mechanotransduction play in the heart, while at the same time introducing new developments in cellular, viral, and non-biologic therapies that are in the process of being developed. Importantly, the focus of this book is on topics that, due to their novelty, are largely not covered in the other major textbooks. A special emphasis is placed on the molecular basis of cardiac metabolism, new concepts in cardiac remodeling, and translational therapies and imaging techniques currently under development for clinical use. The chapters are written by experts from diverse clinical and biomedical research backgrounds. Translational Cardiology: Molecular Basis of Cardiac Metabolism, Cardiac Remodeling, Translational Therapies and Imaging Techniques simplifies the complexity of the molecular basis of disease by focusing on patient-oriented disease mechanisms and therapies and is of great value to a broad audience including physicians (e.g. cardiologists, cardiovascular surgeons, pathologists) as well as translational biomedical researchers in a wide range of disciplines.

Author : Dennis V. Cokkinos
Publisher : Springer
Page : 609 pages
File Size : 54,9 Mb
Release : 2014-11-06
Category : Medical
ISBN : 9783319087986

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Introduction to Translational Cardiovascular Research by Dennis V. Cokkinos Pdf

The term “Translational Research” reflects today’s integration of basic research (“bench”) findings with the clinical practice of medicine, and in a wider scope the application of results from the individual patient (“bedside”) to entire populations for the improvement of public health. This book offers future researchers a stimulus in many aspects of cardiovascular research, so as to promote their interest in future fields of cardiovascular disease, diagnosis and treatment. Introduction to Translational Cardiovascular Research discusses the fundamental and important aspects of the topic. It describes the renin-angiotensin-aldosterone system, the beta adrenergic receptors and the hypothalamic-pituitary-adrenal axis, while covering genetic polymorphisms both generally and specifically as regards the vascular endothelium and the use of microRNAs. As such, this book will be relevant to young physicians, nurses and other scientists engaged in the clinical cardiovascular field who want to added research-oriented dimension to their efforts towards better understanding and practicing of medicine. It also aims to attract young basic researchers who want to develop a better comprehension of the organism as a whole, man or animal, that they are investigating.

Author : Jozef Bartunek,Marc Vanderheyden
Publisher : Springer Science & Business Media
Page : 501 pages
File Size : 43,6 Mb
Release : 2013-07-13
Category : Medical
ISBN : 9781461473459

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Translational Approach to Heart Failure by Jozef Bartunek,Marc Vanderheyden Pdf

The refined pathophysiologal understanding of the heart failure syndrome together with the surge of new technological advances led to innovative medical and interventional treatment strategies improving the outcome of heart failure patients. However the complex interplay between the clinical presentation and the array of the interventions requires a coordinated multidisciplinary “heart team” approach involving various specialists in the cardiovascular field including clinicians, interventionalists, surgeons and cardiac intensivists. In this book, opinion leaders will review of state-of-the-art management of heart failure with particular emphasis on burning clinical questions and challenges faced by the heart team. New medical and interventional therapies for chronic and acute heart failure are addressed by bridging bench to bedside translation in science and technology into practical clinical application and guidance.

Author : Anonim
Publisher : Springer
Page : 560 pages
File Size : 50,8 Mb
Release : 2012-08-01
Category : Electronic
ISBN : 1617798924

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Translational Cardiology by Anonim Pdf

Author : Jeffrey A. Bakal,Michael Gibson,Adam E.M. Eltorai
Publisher : Academic Press
Page : 0 pages
File Size : 42,5 Mb
Release : 2025-01-01
Category : Science
ISBN : 0323917909

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Translational Cardiology by Jeffrey A. Bakal,Michael Gibson,Adam E.M. Eltorai Pdf

Translational research is essential to the advancement of medicine. This Cardiology-specific instructional guide to translational medical research serves as a practical, step-by-step roadmap for taking a biomedical device, potential therapeutic agent, or research question from idea through demonstrated clinical benefit. Fundamentally, the volume aims to help bridge the gap between current research and practice. Written by a team of expert medical, biomedical engineering, and clinical research experts in Cardiology, this volume provides a clear process for understanding, designing, executing, and analyzing clinical and translational research

Author : Wilbert S. Aronow,John Arthur McClung
Publisher : Academic Press
Page : 244 pages
File Size : 47,7 Mb
Release : 2015-10-29
Category : Medical
ISBN : 9780128026052

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Translational Research in Coronary Artery Disease by Wilbert S. Aronow,John Arthur McClung Pdf

Translational Research in Coronary Artery Disease: Pathophysiology to Treatment covers the entire spectrum of basic science, genetics, drug treatment, and interventions for coronary artery disease. With an emphasis on vascular biology, this reference fully explains the fundamental aspects of coronary artery disease pathophysiology. Included are important topics, including endothelial function, endothelial injury, and endothelial repair in various disease states, vascular smooth muscle function and its interaction with the endothelium, and the interrelationship between inflammatory biology and vascular function. By providing this synthesis of current research literature, this reference allows the cardiovascular scientist and practitioner to access everything they need from one source. Provides a concise summary of recent developments in coronary and vascular research, including previously unpublished data Summarizes in-depth discussions of the pathobiology and novel treatment strategies for coronary artery disease Provides access to an accompanying website that contains photos and videos of noninvasive diagnostic modalities for evaluation of coronary artery disease

Author : Endre Zima
Publisher : BoD – Books on Demand
Page : 154 pages
File Size : 48,7 Mb
Release : 2022-03-09
Category : Medical
ISBN : 9781839695056

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Cardiac Arrhythmias by Endre Zima Pdf

Cardiac arrhythmias are common triggers of emergency admission to cardiology or high-dependency departments. Most cases are easy to diagnose and treat, while others may present a challenge to healthcare professionals. A translational approach to arrhythmias links molecular and cellular scientific research with clinical diagnostics and therapeutic methods, which may include both pharmacological and non-pharmacologic treatments. This book presents a comprehensive overview of specific cardiac arrhythmias and discusses translational approaches to their diagnosis and treatment.

Author : Dennis V. Cokkinos
Publisher : Springer
Page : 405 pages
File Size : 47,5 Mb
Release : 2019-01-28
Category : Medical
ISBN : 9783319981864

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Myocardial Preservation by Dennis V. Cokkinos Pdf

This timely book reveals an integrated approach to myocardial preservation focusing on translational research and clinical applications. Chapters cover both the mechanisms of heart failure in addition to therapeutic considerations, including forms of cardiac cell death, cardiac remodelling and cardiac regeneration. Potential future research directions are also proposed, enabling the reader to gain a broad in-depth understanding of the topic. Myocardial Preservation: Translational Research and Clinical Application presents a thorough review of myocardial preservation. Its comprehensive approach provides a valuable reference for cardiology researchers and practising and trainee cardiologists seeking new insight to the topic.

Author : Ragavendra R. Baliga,George A. Mensah
Publisher : Elsevier Health Sciences
Page : 217 pages
File Size : 47,5 Mb
Release : 2022-06-23
Category : Medical
ISBN : 9780323987486

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Translational Research in Cardio-Oncology, An Issue of Heart Failure Clinics by Ragavendra R. Baliga,George A. Mensah Pdf

In this issue of Heart Failure Clinics, guest editors Drs. Ragavendra R Baliga and George A. Mensah bring their considerable expertise to the topic of Translational Research in Cardio-Oncology. Top experts in the field cover key topics such as radiation-induced cardiac dysfunction; training and career development; cardiovascular imaging; CAR-T cell therapy and cardiovascular disease; and more. Contains 12 relevant, practice-oriented topics including cardio-protection of high-risk individuals; myocardial metabolism; amyloidosis; arrhythmic complications associated with cancer therapies; and more. Provides in-depth clinical reviews on translational research in cardio-oncology, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Author : Anonim
Publisher : Elsevier
Page : 2800 pages
File Size : 41,7 Mb
Release : 2017-11-27
Category : Medical
ISBN : 9780128051542

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Encyclopedia of Cardiovascular Research and Medicine by Anonim Pdf

Encyclopedia of Cardiovascular Research and Medicine offers researchers over 200 articles covering every aspect of cardiovascular research and medicine, including fully annotated figures, abundant color illustrations and links to supplementary datasets and references. With contributions from top experts in the field, this book is the most reputable and easily searchable resource of cardiovascular-focused basic and translational content for students, researchers, clinicians and teaching faculty across the biomedical and medical sciences. The panel of authors chosen from an international board of leading scholars renders the text trustworthy, contemporary and representative of the global scientific expertise in these domains. The book's thematic structuring of sections and in-depth breakdown of topics encourages user-friendly, easily searchable chapters. Cross-references to related articles and links to further reading and references will further guide readers to a full understanding of the topics under discussion. Readers will find an unparalleled, one-stop resource exploring all major aspects of cardiovascular research and medicine. Presents comprehensive coverage of every aspect of cardiovascular medicine and research Offers readers a broad, interdisciplinary overview of the concepts in cardiovascular research and medicine with applications across biomedical research Includes reputable, foundational content on genetics, cancer, immunology, cell biology and molecular biology Provides a multi-media enriched color-illustrated text with high quality images, graphs and tables.

Author : Sharmila Dorbala,Piotr Slomka
Publisher : Elsevier Health Sciences
Page : 128 pages
File Size : 52,5 Mb
Release : 2016-01-07
Category : Medical
ISBN : 9780323416832

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Nuclear Cardiology, An Issue of Cardiology Clinics, by Sharmila Dorbala,Piotr Slomka Pdf

This issue of Cardiology Clinics, edited by Sharmila Dorbala and Piotr Slomka, examines Nuclear Cardiology. Topics include Advances in SPECT Hardware and Software; Advances in PET Hardware and Software; Technical Advances and Clinical Applications of Cardiac PET/MR; Translational Coronary Atherosclerosis Imaging (NaF PET, FDG); Quantitative Nuclear Cardiology Using New Generation Equipment; Myocardial Perfusion Flow Tracers; Translational Molecular Nuclear Cardiology; Radionuclide Imaging in Congestive Heart Failure (Sarcoid, Amyloid, Viability); Clinical Applications of Imaging Myocardial Innervation; Gated Radionuclide Imaging Including Dyssynchrony Assessment; Clinical PET Myocardial Perfusion Imaging Including Flow Quantitation; and Novel Applications of Radionuclide Imaging in Peripheral Vascular Disease.

Author : David Abraham,Clive Handler,Michael Dashwood,Gerry Coghlan
Publisher : Springer Science & Business Media
Page : 268 pages
File Size : 44,5 Mb
Release : 2011-11-19
Category : Medical
ISBN : 9780857299208

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Translational Vascular Medicine by David Abraham,Clive Handler,Michael Dashwood,Gerry Coghlan Pdf

Translational medicine underpins vascular medicine. It is fundamental to understanding how we treat patients with vascular disease and more importantly, how to prevent it. It is the rationale for drug design and production. Vascular medicine and translational medicine will take over and become the main reason for referring patients to hospital. Therefore, hospital-based clinicians working with basic scientists need to know about translational medicine, which educates and informs them about vascular medicine and how management should be based. This book is a primer for translational vascular medicine and discusses the evolving and exciting areas of basic science applied to vascular medicine. The book is based on the third vascular biology conference held at The Royal College of Physicians in 2008. It provides a large amount of new basic and clinical information and the contributors are world leaders.

Author : Dorairaj Prabhakaran,Raman Krishna Kumar,Nitish Naik
Publisher : Wolters kluwer india Pvt Ltd
Page : 1700 pages
File Size : 47,7 Mb
Release : 2019-01-17
Category : Medical
ISBN : 9789388696166

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Tandon’s Textbook of Cardiology by Dorairaj Prabhakaran,Raman Krishna Kumar,Nitish Naik Pdf

An authoritative, comprehensive, and accessible cardiology textbook that caters to the needs of trainees and practicing cardiologists. Cardiovascular disease is now the largest contributor to global mortality. Low and middle income countries. (Lmics) presently bear the brunt of this global epidemic, accounting for over three quarters of cardiovascular deaths and 90% of these deaths under 70 years of age. The experience and expertise of health professionals in these countries will therefore be the principal determinant of global success in countering and curbing the global cardiovascular epidemic in the coming decades. This book covers the fundamentals of cardiology in depth, to provide conceptual clarity, and delves into specific cardiovascular disorders with detailed descriptions that range from aetiology and pathophysiology to evidence informed approaches to diagnosis and management. It does all of this by blending contextual relevance with uncompromising academic rigor.

Author : José Marín-García
Publisher : Academic Press
Page : 935 pages
File Size : 45,9 Mb
Release : 2014-05-09
Category : Medical
ISBN : 9780124046429

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Post-Genomic Cardiology by José Marín-García Pdf

In this second edition of Post-Genomic Cardiology, developing and new technologies such as translational genomics, next generation sequencing (NGS), bioinformatics, and systems biology in molecular cardiology are assessed in light of their therapeutic potential. As new methods of mutation screening emerge, both for the genome and for the “epigenome, comprehensive understanding of the many mutations that underlie cardiovascular diseases and adverse drug reactions is within our reach. This book, written by respected cardiologist José Marín-García, features discussion on the Hap-Map: the largest international effort to date aiming to define the differences between our individual genomes. This unique reference further reviews and investigates genome sequences from our evolutionary relatives that could help us decipher the signals of genes, and offers a comprehensive and critical evaluation of regulatory elements from the complicated network of the background DNA. Offers updated discussion of cutting-edge molecular techniques including new genomic sequencing / NGS / Hap-Map / bioinformatics / systems biology approaches Analyzes mitochondria dynamics and their role in cardiac dysfunction, up-to-date analysis of cardio-protection, and cardio-metabolic syndrome Presents recent translational studies, gene therapy, transplantation of stem cells, and pharmacological treatments in CVDs

Author : Giuseppe Limongelli,Eduardo Bossone
Publisher : Elsevier Health Sciences
Page : 225 pages
File Size : 52,9 Mb
Release : 2021-11-18
Category : Medical
ISBN : 9780323919883

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Rare Cardiovascular Diseases, An Issue of Heart Failure Clinics, E-Book by Giuseppe Limongelli,Eduardo Bossone Pdf

In this issue of Heart Failure Clinics, Guest Editors Giuseppe Limongelli and Eduardo Bossone bring their considerable expertise to the topic of rare cardiovascular diseases. Top experts in the field cover key topics such as coronary artery dissection, genetics in congenital heart disease, HCM in Rasopathies, and more. Provides in-depth, clinical reviews on Rare Cardiovascular Diseases, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews. Contains 17 relevant, practice-oriented topics including The influence of genotype on the phenotype, clinical course, and risk of adverse events in children with Hypertrophic cardiomyopathy; Unravelling the genetic background in heritable and non-heritable BAV: a long roadmap; The risk of sudden unexpected cardiac death in children: epidemiology, clinical causes, and prevention; The renal involvement in patients with storage and infiltrative cardiomyopathies; and more.