Translational Systems Medicine And Oral Disease

Author : Stephen Sonis,Alessandro Villa
Publisher : Academic Press
Page : 458 pages
File Size : 41,8 Mb
Release : 2019-09-14
Category : Medical
ISBN : 9780128137635

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Translational Systems Medicine and Oral Disease by Stephen Sonis,Alessandro Villa Pdf

Translational Systems Medicine and Oral Disease bridges the gap between discovery science and clinical oral medicine, providing opportunities for both the scientific and clinical communities to understand how to apply recent findings in cell biology, genomic profiling, and systems medicine to favorably impact the diagnosis, treatment and management of oral diseases. Fully illustrated chapters from leading international contributors explore clinical applications of genomics, proteomics, metabolomics, microbiomics and epigenetics, as well as analytic methods and functional omics in oral medicine. Disease specific chapters detail systems approaches to periodontal disease, salivary gland diseases, oral cancer, bone disease, and autoimmune disease, among others. In addition, the book emphasizes biological synergisms across disciplines and their translational impact for clinicians, researchers and students in the fields of dentistry, dermatology, gastroenterology, otolaryngology, oncology and primary care. Presents the work of leading international researchers and clinicians who speak on the clinical applications of genomics, proteomics, metabolomics, microbiomics, and epigenetics, as well as analytic methods and functional omics in oral medicine Provides full-color, richly illustrated chapters that examine systems approaches to periodontal disease, salivary gland diseases, oral cancer, bone disease and autoimmune diseases Includes clinical case studies that illustrate examples of oral disease diagnostics and management, highlighting points of key importance for the reader Emphasizes biological synergisms across disciplines and their translational impact for clinicians, researchers, and students in the fields of dentistry, dermatology, gastroenterology, otolaryngology, oncology, and primary care

Author : Jukka H. Meurman
Publisher : Springer
Page : 173 pages
File Size : 54,6 Mb
Release : 2018-06-18
Category : Medical
ISBN : 9783319782058

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Translational Oral Health Research by Jukka H. Meurman Pdf

This book is the first to be devoted to translational research – which aims to expedite the transfer of knowledge gained in the lab to clinical practice – within the field of oral health. It is examined how basic sciences and basic research are providing new methods and materials that will enable clinicians to treat patients more effectively. Readers will gain a translational perspective on a variety of oral conditions and related systemic diseases. Individual chapters are devoted to such topics as dental biomaterials, implants, and tissue engineering. The importance of evidence-based research and the roles and comparative value of preclinical and clinical trials are also highlighted. Knowledge of translational and clinical research is essential in understanding how new inventions and developments are being accomplished, and what regulations and guidelines need to be taken into account when planning studies, and not forgetting the ethical aspects of any research. Translational Oral Health Research is the first book to be devoted entirely to the subject, and it will be of interest to both researchers and practitioners.

Author : Brian Henderson,Michael Curtis,Robert Seymour,Nikolaos Donos
Publisher : John Wiley & Sons
Page : 465 pages
File Size : 53,8 Mb
Release : 2009-07-07
Category : Medical
ISBN : 9781405122191

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Periodontal Medicine and Systems Biology by Brian Henderson,Michael Curtis,Robert Seymour,Nikolaos Donos Pdf

This book provides a systems-based approach to periodontology and offers a scientific roadmap of the interactions which can lead to periodontal disease.

Author : Georgios N. Belibasakis,George Hajishengallis,Nagihan Bostanci,Michael A. Curtis
Publisher : Springer Nature
Page : 192 pages
File Size : 50,5 Mb
Release : 2019-11-15
Category : Medical
ISBN : 9783030285241

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Oral Mucosal Immunity and Microbiome by Georgios N. Belibasakis,George Hajishengallis,Nagihan Bostanci,Michael A. Curtis Pdf

The first International Conference on Oral Mucosal Immunity and Microbiome (OMIM) aimed to highlight cutting-edge basic and translational research from an oral immunological and microbiological perspective. Oral diseases with a microbial etiology are the most prevalent chronic diseases of humans. Whilst not life-threatening, they can significantly compromise quality of life, are associated with increased risk for certain systemic diseases, and pose heavy financial burdens to national health systems. Hence, periodontal and peri-implant diseases, dental caries, root canal infections and mucosal infections are significant global public health problems. In this book global experts summarize and discuss the latest progress made in oral mucosal immunity and the oral microbiome. Target audience is basic and/or translational researchers with expertise in host immunity and microbiome research, and interest in oral health and disease. This volume provides a much needed quantum leap in the field, by joining forces to address gaps at the oral mucosal immunity-microbiome cross-talk.

Author : Gary D. Miner,Linda A. Miner,Scott Burk,Mitchell Goldstein,Robert Nisbet,Nephi Walton,Thomas Hill
Publisher : Academic Press
Page : 578 pages
File Size : 40,8 Mb
Release : 2023-02-08
Category : Computers
ISBN : 9780323952750

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Practical Data Analytics for Innovation in Medicine by Gary D. Miner,Linda A. Miner,Scott Burk,Mitchell Goldstein,Robert Nisbet,Nephi Walton,Thomas Hill Pdf

Practical Data Analytics for Innovation in Medicine: Building Real Predictive and Prescriptive Models in Personalized Healthcare and Medical Research Using AI, ML, and Related Technologies, Second Edition discusses the needs of healthcare and medicine in the 21st century, explaining how data analytics play an important and revolutionary role. With healthcare effectiveness and economics facing growing challenges, there is a rapidly emerging movement to fortify medical treatment and administration by tapping the predictive power of big data, such as predictive analytics, which can bolster patient care, reduce costs, and deliver greater efficiencies across a wide range of operational functions. Sections bring a historical perspective, highlight the importance of using predictive analytics to help solve health crisis such as the COVID-19 pandemic, provide access to practical step-by-step tutorials and case studies online, and use exercises based on real-world examples of successful predictive and prescriptive tools and systems. The final part of the book focuses on specific technical operations related to quality, cost-effective medical and nursing care delivery and administration brought by practical predictive analytics. Brings a historical perspective in medical care to discuss both the current status of health care delivery worldwide and the importance of using modern predictive analytics to help solve the health care crisis Provides online tutorials on several predictive analytics systems to help readers apply their knowledge on today’s medical issues and basic research Teaches how to develop effective predictive analytic research and to create decisioning/prescriptive analytic systems to make medical decisions quicker and more accurate

Author : Anupam Nath Jha,Sandeep Swargam,Indu Kumari
Publisher : Bentham Science Publishers
Page : 335 pages
File Size : 44,5 Mb
Release : 2023-11-08
Category : Science
ISBN : 9789815165623

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Systems Biology, Bioinformatics and Livestock Science by Anupam Nath Jha,Sandeep Swargam,Indu Kumari Pdf

This book explores the intricate world of livestock sciences and production through the lens of systems biology. Offering a comprehensive exploration of both fundamental and advanced aspects, it unearths the potential of systems biology in the realm of livestock. The book presents 13 edited chapters on cutting-edge knowledge about systems biology and omics technology, showcasing genomics, transcriptomics, proteomics, metabolomics, and more. It illuminates the role of systems biology in livestock and disease management. Readers will learn about power of technologies that merge computational biology, nanobiotechnology, artificial intelligence, and single-cell sequencing. Each chapter is written by scientific experts and includes references for further reading. The book covers 4 key themes: Introduction to Systems Biology in Livestock Science: Uncover the foundation of integrating systems biology with omics data for animal scientists. Multi-scale Modeling Techniques: Explore how multi-scale modeling is shaping the future of system biology. Livestock Viral Diseases: Gain insights into how systems biology is revolutionizing our understanding of livestock viral diseases. Single Cell RNA-Sequencing: Understand the potential of this advanced technique in studying livestock animals at a cellular level. This book is a timely resource for students and researchers, offering a pathway to comprehend the crucial role systems biology plays in sustainable livestock production and management.

Author : Imran Kazmi,Sanmoy Karmakar,Md Adil Shaharyar,Muhammad Afzal,Fahad A. Al-Abbasi
Publisher : Academic Press
Page : 601 pages
File Size : 46,5 Mb
Release : 2022-09-06
Category : Medical
ISBN : 9780323913683

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How Synthetic Drugs Work by Imran Kazmi,Sanmoy Karmakar,Md Adil Shaharyar,Muhammad Afzal,Fahad A. Al-Abbasi Pdf

How Synthetic Drugs Work: Insights into Molecular Pharmacology of Classic and New Pharmaceuticals provides comprehensive, structured access to robust information on molecular pharmacology for clinicians, research scientists and advanced health care students. The book covers the foundations of molecular pharmacology and the main drug classes, including detailed information on their mechanisms of action and the application of molecular pharmacology in drug development. This book is an ideal reference for graduate students and researchers in pharmacology, however, researchers in corporate settings will also benefit from the book's structured and detailed coverage of mechanisms of action of synthetic drugs. Presents the mechanism of action of most recent synthetic drugs available Includes newly reported action mechanisms of conventional drugs Contains colored illustrations of the pathway through which the drug exerts therapeutic action

Author : Sajal Chakraborti
Publisher : Springer Nature
Page : 4078 pages
File Size : 49,9 Mb
Release : 2022-09-28
Category : Medical
ISBN : 9789811654220

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Handbook of Oxidative Stress in Cancer: Therapeutic Aspects by Sajal Chakraborti Pdf

This reference book, which is the second volume of Targeting Oxidative Stress in Cancer, explores oxidative stress as the potential therapeutic target for cancer therapy. The initial chapters discuss the molecular mechanisms of oxidative stress and its effects on different signaling pathways. Subsequently, the sections examine the impact of redox signaling on tumor cell proliferation and consider the therapeutic potential of dietary phytochemicals and nutraceuticals in reactive oxygen species (ROS)-induced cancer. In turn, it examines the evidence supporting the use of Vitamin C in cancer management, before presenting various synthetic and natural compounds that have therapeutic implications for oxidative stress-induced cancer. It also explores the correlation between non-coding RNA and oxidative stress. Furthermore, the book summarizes the role of stem cells in ROS-induced cancer therapy and reviews the therapeutic applications of nanoparticles to alter redox haemostasis in cancer cells. Lastly, it explores heat-shock proteins, ubiquitin ligases, and probiotics as potential therapeutic agents in ROS-mediated cancer. This book is a useful resource for basic and translational scientists as well as clinicians interested in the field of oxidative stress and cancer therapy. ​

Author : William V. Giannobile,Brian A. Burt,Robert J. Genco
Publisher : John Wiley & Sons
Page : 394 pages
File Size : 47,5 Mb
Release : 2009-12-09
Category : Medical
ISBN : 9780813820552

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Clinical Research in Oral Health by William V. Giannobile,Brian A. Burt,Robert J. Genco Pdf

Clinical Research in Oral Health surveys the essentials of clinical research in oral health, anchoring these principles within the specific context of the oral health arena. Addressing research questions exclusively applicable to dentistry and oral health, the book thoroughly illustrates the principles and practice of oral health clinical research. Clinical Research in Oral Health also clarifies the framework of regulatory issues and presents emerging concepts in clinical translation, relating the research principles to clinical improvement.

Author : Stephen T. Sonis, DMD, DMSc
Publisher : Springer
Page : 408 pages
File Size : 53,5 Mb
Release : 2015-09-17
Category : Medical
ISBN : 9783319179421

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Genomics, Personalized Medicine and Oral Disease by Stephen T. Sonis, DMD, DMSc Pdf

The objective of this book is to catalyze the application of genomics to the diagnosis and treatment of oral diseases by comprehensively presenting focused discussions on the current state of knowledge. The first section book provides basic information about genetics, genomics and personalized medicine and the informatical methods available to apply and organize genetic data so that it has clinical relevance. Recognizing the genetic robustness of the oral cavity, the introductory section includes chapters on the oral micro biome and host genomics and response to infectious agents. The next two sections contain chapters which describe the genomics of specific oral diseases and conditions, including the genetic basis for mechanism and risk of treatment toxicities associated with cancer therapy and bisphosphonates. Four chapters focus on gene-based therapies and the pharmacogenomics applied to oral disease. The final chapter presents a provocative summary which describes a comprehensive vision of the melding of genomics to personalized medicine and the potential actionable outcomes that will likely affect clinical practice in the upcoming years.

Author : A Sandeep Kranthi Kiran,Seeram Ramakrishna
Publisher : World Scientific
Page : 413 pages
File Size : 53,9 Mb
Release : 2021-04-22
Category : Technology & Engineering
ISBN : 9789811228193

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An Introduction To Biomaterials Science And Engineering by A Sandeep Kranthi Kiran,Seeram Ramakrishna Pdf

This book presents a broad scope of the field of biomaterials science and technology, focusing on theory, advances and applications. It is written for those who would like to develop their interest and knowledge towards biomaterials or materials science and engineering. All aspects of biomaterials science are thoroughly addressed, from basic principles of biomaterials, organs and medical devices to advanced topics such as tissue engineering, surface engineering, sterilization techniques, 3D printing and drug delivery systems. Readers are also introduced to major concepts of surface modification techniques, and potential applications of different classes of biomaterials. Multiple-choice questions at the end of every chapter will be helpful for students to test their understanding of each topic, with answers provided at the end of the book.Ultimately, this book offers a one-stop source of information on the essentials of biomaterials and engineering. It is useful both as an introduction and advanced reference on recent advances in the biomaterials field. Suitable readers include undergraduate and graduate students, especially those in Materials Science, Biomedical Engineering and Bioengineering.

Author : M. Chen
Publisher : Unknown
Page : 360 pages
File Size : 40,6 Mb
Release : 1997
Category : Health & Fitness
ISBN : CHI:57959001

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Comparing Oral Health Care Systems by M. Chen Pdf

Author : Irwin Walter Scopp
Publisher : Mosby
Page : 466 pages
File Size : 53,6 Mb
Release : 1973
Category : Medical
ISBN : UOM:39015000840713

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Oral Medicine by Irwin Walter Scopp Pdf

Author : Anthony Atala,Julie Allickson
Publisher : Academic Press
Page : 606 pages
File Size : 42,7 Mb
Release : 2014-12-01
Category : Science
ISBN : 9780124104570

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Translational Regenerative Medicine by Anthony Atala,Julie Allickson Pdf

Translational Regenerative Medicine is a reference book that outlines the life cycle for effective implementation of discoveries in the dynamic field of regenerative medicine. By addressing science, technology, development, regulatory, manufacturing, intellectual property, investment, financial, and clinical aspects of the field, this work takes a holistic look at the translation of science and disseminates knowledge for practical use of regenerative medicine tools, therapeutics, and diagnostics. Incorporating contributions from leaders in the fields of translational science across academia, industry, and government, this book establishes a more fluid transition for rapid translation of research to enhance human health and well-being. Provides formulaic coverage of the landscape, process development, manufacturing, challenges, evaluation, and regulatory aspects of the most promising regenerative medicine clinical applications Covers clinical aspects of regenerative medicine related to skin, cartilage, tendons, ligaments, joints, bone, fat, muscle, vascular system, hematopoietic /immune system, peripheral nerve, central nervous system, endocrine system, ophthalmic system, auditory system, oral system, respiratory system, cardiac system, renal system, hepatic system, gastrointestinal system, genitourinary system Identifies effective, proven tools and metrics to identify and pursue clinical and commercial regenerative medicine

Author : A. Shabo (Shvo),I. Madsen,H.-U. Prokosch
Publisher : IOS Press
Page : 294 pages
File Size : 46,9 Mb
Release : 2019-04-17
Category : Medical
ISBN : 9781614999591

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ICT for Health Science Research by A. Shabo (Shvo),I. Madsen,H.-U. Prokosch Pdf

Information and Communications Technology (ICT) is used in healthcare and health science research in application domains such as clinical trials and the development of drug and medical devices, as well as in translational medicine, with the aim of improving prevention, diagnosis, and interventions in health and care. This book presents accepted papers from the 2019 European Federation of Medical Informatics conference (EFMI STC 2019), held in Hanover, Germany, from 7 – 10 April 2019. More than 90 submissions were received, from which, after review, the Scientific Program Committee (SPC) accepted 50 full papers to be included in this volume of proceedings. In addition, 16 poster presentations were accepted. This year, ICT for Health Science Research was selected as the focus topic, and the conference also honors Prof. Peter Leo Reichertz (1930 – 1987), one of the founding fathers of ICT healthcare and an originator of the term Medical Informatics. The conference focuses on recent research & development supporting information systems in biomedical, translational and clinical research, as well as semantic interoperability across such systems for the purpose of data sharing and the analytics of cross-system integrated data. Papers are divided into 12 categories covering topics including digitization; data privacy; interoperability; data-driven decision support; mobile data capture; and ICT for clinical trials. The book will be of interest to all healthcare researchers and practitioners whose work involves the use of ICT.