Tumor Progression And Metastasis

Author : Anonim
Publisher : BoD – Books on Demand
Page : 320 pages
File Size : 54,8 Mb
Release : 2020-04-08
Category : Medical
ISBN : 9781789853490

Get Book

Tumor Progression and Metastasis by Anonim Pdf

This book offers significant coverage on different aspects of cancer from risk factors to the mechanisms leading to tumor progression and metastasis. Although tremendous progress has been made in cancer research and treatment, cancer metastasis remains a major unmet clinical need. The life and death of many cancer patients hangs on the degree of metastasis. This book provides new perspectives for diagnosis and cancer therapy. It includes new technologies and a new basis for current cancer therapies. To guarantee the high quality of this book, important topics are included and rigorously discussed in a simple and authentic way. The book addresses important challenges governing tumor progression and metastasis and brings new responses to both diagnosis and therapy. This book is a great source of knowledge and will be useful for researchers, medical doctors, oncologists, graduate and medical students, continued medical educators, health care providers, and all individuals interested in understanding cancer and its challenges.

Author : Ian Tannock
Publisher : McGraw Hill Professional
Page : 596 pages
File Size : 50,7 Mb
Release : 2005
Category : Medical
ISBN : 0071387749

Get Book

The Basic Science of Oncology by Ian Tannock Pdf

This concise text examines cancer causation and biology as well as the biology underlying cancer treatment. Thoroughly updated and reorganized with five new chapters, the Fourth Edition emphasizes new development in molecular biology, hormone therapy, and the pharmacology of anti-cancer drugs. Features updated coverage of the basic science of radiotherapy and experimental radiation in addition to expansive coverage of new drugs developments.

Author : Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland
Publisher : John Wiley & Sons
Page : 2008 pages
File Size : 45,8 Mb
Release : 2017-03-10
Category : Medical
ISBN : 9781119000846

Get Book

Holland-Frei Cancer Medicine by Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland Pdf

Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Author : Hans E. Kaiser,Aejaz Nasir
Publisher : Springer Science & Business Media
Page : 251 pages
File Size : 46,5 Mb
Release : 2008-05-20
Category : Medical
ISBN : 9781402067297

Get Book

Selected Aspects of Cancer Progression: Metastasis, Apoptosis and Immune Response by Hans E. Kaiser,Aejaz Nasir Pdf

The processes of tumor metastasis, apoptosis and anti-tumor immune response are among the most complex yet rapidly advancing fields in the area of cancer research. This monograph, with its leading authorship, presents a comprehensive coverage of the recent advances in the various key concepts in these fundamental aspects of human cancer. It contains state-of-the-science reviews on invasion, metastasis, angiogenesis, apoptosis and immunologic aspects related to cancer.

Author : Yasemin Basbinar,Gizem Calibasi Kocal
Publisher : BoD – Books on Demand
Page : 154 pages
File Size : 48,9 Mb
Release : 2018-12-05
Category : Medical
ISBN : 9781789846324

Get Book

Cancer Metastasis by Yasemin Basbinar,Gizem Calibasi Kocal Pdf

Metastasis of cancer cells from primary tumor site to secondary locations is considered a late event in multistep tumorigenesis, and causes most cancer-related mortality. The process from the spreading of cancer cells to the seeding of newly formed tumor colonizations is governed by sequential events, including local invasion, intravasation into stroma and blood vessels, survival in circulation, extravasation, and colonization at secondary tumor sites. Cancer research provides information on the fate of metastatic cancer cells in each sequential movement or heterogeneous tumor microenvironment. However, the complexity of this mechanism remains the most stringent concept of cancer management. This book provides information for cancer researchers on metastatic phenotypes of cancer cells, and diverse promoting factors and molecular mechanisms of metastasis.

Author : Fred Hollande,Delphine Merino
Publisher : MDPI
Page : 314 pages
File Size : 41,7 Mb
Release : 2021-01-21
Category : Science
ISBN : 9783039288533

Get Book

Metastatic Progression and Tumour Heterogeneity by Fred Hollande,Delphine Merino Pdf

Improved understanding of the cellular and molecular makeup of tumors in the last 30 years has unraveled a previously unexpected level of heterogeneity among tumor cells as well as within the tumor microenvironment. The concept of tumor heterogeneity underlines the realization that different tumors can display significant differences in their genomic content as well as in their overall behavior. Our capacity to better understand the heterogeneous make up of tumors has very important consequences on our ability to design efficient therapeutic strategies to improve patient survival. This book highlights several aspects of tumor heterogeneity in the context of metastatic development and summarize some of the challenges posed by heterogeneity for tumor diagnostics and therapeutic management of tumors.

Author : Anonim
Publisher : Unknown
Page : 128 pages
File Size : 48,6 Mb
Release : 1988
Category : Electronic
ISBN : 0845126776

Get Book

Tumor Progression and Metastasis by Anonim Pdf

Author : Elizier L. Gorelik
Publisher : Springer Science & Business Media
Page : 318 pages
File Size : 48,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789400925342

Get Book

Metastasis / Dissemination by Elizier L. Gorelik Pdf

This volume emphasizes metastasis/dissemination as im nective tissues, muscle, tumours of neuronal origins and portant processes in cancer growth and progression. teratomas. Previous volumes in this series have emphasized aspects of The broad array of neoplastic diseases, multiple target cancer progression, tumor invasion and tumor metastasis sites, and patterns of metastasis and dissemination underlie and the importance of these processes to the pathophysiol the importance of achieving crucial insights into particular ogy and morbidity of malignant disease. This volume builds neoplasms. An understanding of metastasis and dissemina on these earlier themes and emphasizes metastasis/disse tion in man remains an essential objective for the design of mination in man. Following a review of general patterns of new diagnostic and therapeutic strategies for the therapy of metastatic spread in man, metastasis to, or progression of established metastatic disease and spread accompanying neoplasms in several organ systems are highlighted, includ site-specific tumor progression. ing: the central nervous system, esophageal cancer, the lung, the large intestine, the liver, bone, epithelial neoplasms, Series Editor Volume Editor endocrine cells, pigmented tissues, supporting tissues, con- Hans E. Kaiser Elizier L. Gorelik VII ACKNOWLEDGEMENT Inspiration and encouragement for this wide ranging project on cancer distribution and dissemination from a comparative biological and clinical point of view, was given by my late friend E. H. Krokowski.

Author : Chris Maxwell,Cal Roskelley
Publisher : Springer
Page : 247 pages
File Size : 54,5 Mb
Release : 2014-12-04
Category : Medical
ISBN : 9783319121369

Get Book

Genomic Instability and Cancer Metastasis by Chris Maxwell,Cal Roskelley Pdf

Metastasis is the primary cause of mortality associated with cancer, and tumor genomic heterogeneity is a likely source for the cells that support cancer progression, resistance to therapy, and disease relapse. This book connects cancer metastasis with genomic instability in a comprehensive manner. Section 1 outlines the fundamental mechanisms responsible for these cellular and tissue phenotypes. Section 2 discusses in silico, in vitro, and in vivo models used for the experimental study of these processes. Section 3 reviews emerging themes (ex., microenvironment, mechanotransduction, and immunomodulation), and Section 4 highlights new therapeutic approaches to overcome the unique challenges presented by the heterogeneous and metastatic tumor. This book is intended for undergraduates and postgraduates with an interest in the areas of medicine, oncology, and cancer biology as well as for the content expert searching for thorough reviews of current knowledge in these areas.

Author : Ajit Varki,Maarten J. Chrispeels
Publisher : CSHL Press
Page : 694 pages
File Size : 40,9 Mb
Release : 1999
Category : Medical
ISBN : 0879696818

Get Book

Essentials of Glycobiology by Ajit Varki,Maarten J. Chrispeels Pdf

Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.

Author : Antonella Zannetti,Gennaro Ilardi,Wolfgang Link
Publisher : Frontiers Media SA
Page : 566 pages
File Size : 53,7 Mb
Release : 2021-09-30
Category : Medical
ISBN : 9782889714483

Get Book

Tumor Microenvironment: Molecular Mechanisms and Signaling Pathways Involved in Metastatic Progression by Antonella Zannetti,Gennaro Ilardi,Wolfgang Link Pdf

Author : Garth L. Nicolson,Isaiah J. Fidler,Triton Biosciences, Inc,Smith, Kline & French Laboratories,University of California, Los Angeles
Publisher : Unknown
Page : 332 pages
File Size : 46,6 Mb
Release : 1988
Category : Medical
ISBN : UOM:39015013213247

Get Book

Tumor Progression and Metastasis by Garth L. Nicolson,Isaiah J. Fidler,Triton Biosciences, Inc,Smith, Kline & French Laboratories,University of California, Los Angeles Pdf

Author : Anne Le
Publisher : Springer Nature
Page : 283 pages
File Size : 54,9 Mb
Release : 2021-05-20
Category : Medical
ISBN : 9783030657680

Get Book

The Heterogeneity of Cancer Metabolism by Anne Le Pdf

This open access volume will introduce recent discoveries in cancer metabolism since the publication of the first edition in 2018, providing readers with an up-to-date understanding of developments in the field. Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, the authors delve into the complexity and diversity of cancer metabolism and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies for cancer treatment. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer treatment. This book has four major parts. Part one will cover the basic metabolism of cancer cells, followed by a discussion of the heterogeneity of cancer metabolism in part two. Part three addresses the relationship between cancer cells and cancer-associated fibroblasts, and the new part four will explore the metabolic interplay between cancer and other diseases. This new section makes the book unique from other texts currently available on the market. The second edition will be useful for cancer metabolism researchers, cancer biologists, epidemiologists, physicians, health care professionals in related disciplines, policymakers, marketing and economic strategists, among others. It may also be used in courses such as intro to cancer metabolism, cancer biology, and related biochemistry courses for undergraduate and graduate students.

Author : Keshav Singh,Leslie Costello
Publisher : Springer Science & Business Media
Page : 294 pages
File Size : 53,7 Mb
Release : 2009-04-05
Category : Medical
ISBN : 9780387848358

Get Book

Mitochondria and Cancer by Keshav Singh,Leslie Costello Pdf

Nearly a century of scientific research has revealed that mitochondrial dysfunction is one of the most common and consistent phenotypes of cancer cells. A number of notable differences in the mitochondria of normal and cancer cells have been described. These include differences in mitochondrial metabolic activity, molecular composition of mitochondria and mtDNA sequence, as well as in alteration of nuclear genes encoding mitochondrial proteins. This book, Mitochondria and Cancer, edited by Keshav K. Singh and Leslie C. Costello, presents thorough analyses of mitochondrial dysfunction as one of the hallmarks of cancer, discusses the clinical implications of mitochondrial defects in cancer, and as unique cellular targets for novel and selective anti-cancer therapy.

Author : Bozena Smolkova,Julie Earl,Agapi Kataki
Publisher : Unknown
Page : 0 pages
File Size : 44,9 Mb
Release : 2023
Category : Chemotherapy
ISBN : 3036571841

Get Book

Genetic and Epigenetic Regulations of Tumor Progression and Metastasis by Bozena Smolkova,Julie Earl,Agapi Kataki Pdf

Genetic aberrations and epigenetic modifications are critical drivers of cancer progression and metastasis. Although recurrent mutations in primary and metastatic cancers have been shown to be concordant, there are several metastasis-associated mutations responsible for resistance to specific therapies that are frequently located in genes that regulate DNA methylation and chromatin modifications. Recent studies have shown that distinct subgroups of poor-prognosis tumors lack genetic alterations but are epigenetically regulated, pointing to the critical role of epigenetic modifications in cancer progression. This Special Issue provides novel insights into the mechanisms underlying processes associated with cancer cell plasticity and the development of metastatic disease.