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Ultra Low-Power Biomedical Signal Processing by Sandro Augusto Pavlik Haddad,Wouter A. Serdijn Pdf
Often WT systems employ the discrete wavelet transform, implemented on a digital signal processor. However, in ultra low-power applications such as biomedical implantable devices, it is not suitable to implement the WT by means of digital circuitry due to the relatively high power consumption associated with the required A/D converter. Low-power analog realization of the wavelet transform enables its application in vivo, e.g. in pacemakers, where the wavelet transform provides a means to extremely reliable cardiac signal detection. In Ultra Low-Power Biomedical Signal Processing we present a novel method for implementing signal processing based on WT in an analog way. The methodology presented focuses on the development of ultra low-power analog integrated circuits that implement the required signal processing, taking into account the limitations imposed by an implantable device.
Analog IC Design Techniques for Nanopower Biomedical Signal Processing by Chutham Sawigun,Wouter A. Serdijn Pdf
As the requirements for low power consumption and very small physical dimensions in portable, wearable and implantable medical devices are calling for integrated circuit design techniques using MOSFETs operating in the subthreshold regime, this book first revisits some well-known circuit techniques that use CMOS devices biased in subthreshold in order to establish nanopower integrated circuit designs. Based on the these findings, this book shows the development of a class-AB current-mode sample-and-hold circuit with an order of magnitude improvement in its figure of merit compared to other state-of-the-art designs. Also, the concepts and design procedures of 1) single-branch filters 2) follower-integrator-based lowpass filters and 3) modular transconductance reduction techniques for very low frequency filters are presented. Finally, to serve the requirement of a very large signal swing in an energy-based action potential detector, a nanopower class-AB current-mode analog multiplier is designed to handle input current amplitudes of more than 10 times the bias current of the multiplier circuit. The invented filter circuits have been fabricated in a standard 0.18 μ CMOS process in order to verify our circuit concepts and design procedures. Their experimental results are reported.
Ultra-Low-Voltage Frequency Synthesizer and Successive-Approximation Analog-to-Digital Converter for Biomedical Applications by Chung-Chih Hung,Shih-Hsing Wang Pdf
This book introduces the origin of biomedical signals and the operating principles behind them and introduces the characteristics of common biomedical signals for subsequent signal measurement and judgment. Since biomedical signals are captured by wearable devices, sensor devices, or implanted devices, these devices are all battery-powered to maintain long working time. We hope to reduce their power consumption to extend service life, especially for implantable devices, because battery replacement can only be done through surgery. Therefore, we must understand how to design low-power integrated circuits. Both implantable and in-vitro medical signal detectors require two basic components to collect and transmit biomedical signals: an analog-to-digital converter and a frequency synthesizer because these measured biomedical signals are wirelessly transmitted to the relevant receiving unit. The core unit of wireless transmission is the frequency synthesizer, which provides a wide frequency range and stable frequency to demonstrate the quality and performance of the wireless transmitter. Therefore, the basic operating principle and model of the frequency synthesizer are introduced. We also show design examples and measurement results of a low-power low-voltage integer-N frequency synthesizer for biomedical applications. The detection of biomedical signals needs to be converted into digital signals by an analog-to-digital converter to facilitate subsequent signal processing and recognition. Therefore, the operating principle of the analog-to-digital converter is introduced. We also show implementation examples and measurement results of low-power low-voltage analog-to-digital converters for biomedical applications.
Ultra Low Power Bioelectronics by Rahul Sarpeshkar Pdf
This book provides, for the first time, a broad and deep treatment of the fields of both ultra low power electronics and bioelectronics. It discusses fundamental principles and circuits for ultra low power electronic design and their applications in biomedical systems. It also discusses how ultra energy efficient cellular and neural systems in biology can inspire revolutionary low power architectures in mixed-signal and RF electronics. The book presents a unique, unifying view of ultra low power analog and digital electronics and emphasizes the use of the ultra energy efficient subthreshold regime of transistor operation in both. Chapters on batteries, energy harvesting, and the future of energy provide an understanding of fundamental relationships between energy use and energy generation at small scales and at large scales. A wealth of insights and examples from brain implants, cochlear implants, bio-molecular sensing, cardiac devices, and bio-inspired systems make the book useful and engaging for students and practicing engineers.
Ultra Low Power ECG Processing System for IoT Devices by Temesghen Tekeste Habte,Hani Saleh,Baker Mohammad,Mohammed Ismail Pdf
This book describes an ECG processing architecture that guides biomedical SoC developers, from theory to implementation and testing. The authors provide complete coverage of the digital circuit implementation of an ultra-low power biomedical SoC, comprised of a detailed description of an ECG processor implemented and fabricated on chip. Coverage also includes the challenges and tradeoffs of designing ECG processors. Describes digital circuit architecture for implementing ECG processing algorithms on chip; Includes coverage of signal processing techniques for ECG processing; Features ultra-low power circuit design techniques; Enables design of ECG processing architectures and their respective on-chip implementation.
Biopotential Readout Circuits for Portable Acquisition Systems by Refet Firat Yazicioglu,Chris van Hoof,Robert Puers Pdf
Biopotential Readout Circuits for Portable Acquisition Systems describes one of the main building blocks of such miniaturized biomedical signal acquisition systems. The focus of this book is on the implementation of low-power and high-performance integrated circuit building blocks that can be used to extract biopotential signals from conventional biopotential electrodes. New instrumentation amplifier architectures are introduced and their design is described in detail. These amplifiers are used to implement complete acquisition demonstrator systems that are a stepping stone towards practical miniaturized and low-power systems.
Analog IC Design Techniques for Nanopower Biomedical Signal Processing by Chutham Sawigun,Wouter A. Serdijn Pdf
As the requirements for low power consumption and very small physical dimensions in portable, wearable and implantable medical devices are calling for integrated circuit design techniques using MOSFETs operating in the subthreshold regime, this book first revisits some well-known circuit techniques that use CMOS devices biased in subthreshold in order to establish nanopower integrated circuit designs. Based on the these findings, this book shows the development of a class-AB current-mode sample-and-hold circuit with an order of magnitude improvement in its figure of merit compared to other state-of-the-art designs. Also, the concepts and design procedures of 1) single-branch filters 2) follower-integrator-based lowpass filters and 3) modular transconductance reduction techniques for very low frequency filters are presented. Finally, to serve the requirement of a very large signal swing in an energy-based action potential detector, a nanopower class-AB current-mode analog multiplier is designed to handle input current amplitudes of more than 10 times the bias current of the multiplier circuit. The invented filter circuits have been fabricated in a standard 0.18 µ CMOS process in order to verify our circuit concepts and design procedures. Their experimental results are reported.
Analog-and-Algorithm-Assisted Ultra-low Power Biosignal Acquisition Systems by Venkata Rajesh Pamula,Chris Van Hoof,Marian Verhelst Pdf
This book discusses the design and implementation aspects of ultra-low power biosignal acquisition platforms that exploit analog-assisted and algorithmic approaches for power savings.The authors describe an approach referred to as “analog-and-algorithm-assisted” signal processing.This enables significant power consumption reductions by implementing low power biosignal acquisition systems, leveraging analog preprocessing and algorithmic approaches to reduce the data rate very early in the signal processing chain.They demonstrate savings for wearable sensor networks (WSN) and body area networks (BAN), in the sensors’ stimulation power consumption, as well in the power consumption of the digital signal processing and the radio link. Two specific implementations, an adaptive sampling electrocardiogram (ECG) acquisition and a compressive sampling (CS) photoplethysmogram (PPG) acquisition system, are demonstrated. First book to present the so called, “analog-and-algorithm-assisted” approaches for ultra-low power biosignal acquisition and processing platforms; Covers the recent trend of “beyond Nyquist rate” signal acquisition and processing in detail, including adaptive sampling and compressive sampling paradigms; Includes chapters on compressed domain feature extraction, as well as acquisition of photoplethysmogram, an emerging optical sensing modality, including compressive sampling based PPG readout with embedded feature extraction; Discusses emerging trends in sensor fusion for improving the signal integrity, as well as lowering the power consumption of biosignal acquisition systems.
Sophisticated techniques for signal processing are now available to the biomedical specialist! Written in an easy-to-read, straightforward style, Biomedical Signal Processing presents techniques to eliminate background noise, enhance signal detection, and analyze computer data, making results easy to comprehend and apply. In addition to examining techniques for electrical signal analysis, filtering, and transforms, the author supplies an extensive appendix with several computer programs that demonstrate techniques presented in the text.
Low Power Analog CMOS for Cardiac Pacemakers by Fernando Silveira,Denis Flandre Pdf
Low Power Analog CMOS for Cardiac Pacemakers proposes new techniques for the reduction of power consumption in analog integrated circuits. Our main example is the pacemaker sense channel, which is representative of a broader class of biomedical circuits aimed at qualitatively detecting biological signals. The first and second chapters are a tutorial presentation on implantable medical devices and pacemakers from the circuit designer point of view. This is illustrated by the requirements and solutions applied in our implementation of an industrial IC for pacemakers. There from, the book discusses the means for reduction of power consumption at three levels: base technology, power-oriented analytical synthesis procedures and circuit architecture.
Biomedical Signal Analysis for Connected Healthcare by Sridhar Krishnan Pdf
Biomedical Signal Analysis for Connected Healthcare provides rigorous coverage on several generations of techniques, including time domain approaches for event detection, spectral analysis for interpretation of clinical events of interest, time-varying signal processing for understanding dynamical aspects of complex biomedical systems, the application of machine learning principles in enhanced clinical decision-making, the application of sparse techniques and compressive sensing in providing low-power applications that are essential for wearable designs, the emerging paradigms of the Internet of Things, and connected healthcare. Provides comprehensive coverage of biomedical engineering, technologies, and healthcare applications of various physiological signals Covers vital signals, including ECG, EEG, EMG and body sounds Includes case studies and MATLAB code for selected applications
Practical Biomedical Signal Analysis Using MATLAB® by Katarzyna J. Blinowska,Jarosław Żygierewicz Pdf
Covering the latest cutting-edge techniques in biomedical signal processing while presenting a coherent treatment of various signal processing methods and applications, this second edition of Practical Biomedical Signal Analysis Using MATLAB® also offers practical guidance on which procedures are appropriate for a given task and different types of data. It begins by describing signal analysis techniques—including the newest and most advanced methods in the field—in an easy and accessible way, illustrating them with Live Script demos. MATLAB® routines are listed when available, and freely available software is discussed where appropriate. The book concludes by exploring the applications of the methods to a broad range of biomedical signals while highlighting common problems encountered in practice. These chapters have been updated throughout and include new sections on multiple channel analysis and connectivity measures, phase-amplitude analysis, functional near-infrared spectroscopy, fMRI (BOLD) signals, wearable devices, multimodal signal analysis, and brain-computer interfaces. By providing a unified overview of the field, this book explains how to integrate signal processing techniques in biomedical applications properly and explores how to avoid misinterpretations and pitfalls. It helps readers to choose the appropriate method as well as design their own methods. It will be an excellent guide for graduate students studying biomedical engineering and practicing researchers in the field of biomedical signal analysis. Features: Fully updated throughout with new achievements, technologies, and methods and is supported with over 40 original MATLAB Live Scripts illustrating the discussed techniques, suitable for self-learning or as a supplement to college courses Provides a practical comparison of the advantages and disadvantages of different approaches in the context of various applications Applies the methods to a variety of signals, including electric, magnetic, acoustic, and optical Katarzyna J. Blinowska is a Professor emeritus at the University of Warsaw, Poland, where she was director of Graduate Studies in Biomedical Physics and head of the Department of Biomedical Physics. Currently, she is employed at the Institute of Biocybernetics and Biomedical Engineering of the Polish Academy of Sciences. She has been at the forefront in developing new advanced time-series methods for research and clinical applications. Jarosław Żygierewicz is a Professor at the University of Warsaw, Poland. His research focuses on developing methods for analyzing EEG and MEG signals, brain-computer interfaces, and applications of machine learning in signal processing and classification.
Practical Biomedical Signal Analysis Using MATLAB® by Katarzyn J. Blinowska,Jaroslaw Zygierewicz Pdf
Practical Biomedical Signal Analysis Using MATLAB® presents a coherent treatment of various signal processing methods and applications. The book not only covers the current techniques of biomedical signal processing, but it also offers guidance on which methods are appropriate for a given task and different types of data. The first several chapters of the text describe signal analysis techniques—including the newest and most advanced methods—in an easy and accessible way. MATLAB routines are listed when available and freely available software is discussed where appropriate. The final chapter explores the application of the methods to a broad range of biomedical signals, highlighting problems encountered in practice. A unified overview of the field, this book explains how to properly use signal processing techniques for biomedical applications and avoid misinterpretations and pitfalls. It helps readers to choose the appropriate method as well as design their own methods.
