Ultrastructure Of The Connective Tissue Matrix

Author : P. Motta,A. Ruggeri
Publisher : Springer Science & Business Media
Page : 224 pages
File Size : 46,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461328315

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Ultrastructure of the Connective Tissue Matrix by P. Motta,A. Ruggeri Pdf

In recent years, the techniques of electron microscopy have developed so widely and rapidly that they now cover the fields of research once the unique ll:panage of sister research techniques such as biochemistry, physiology, immunology, X-ray diffraction, etc. It is now possible to reach molecular and submolecular levels, making this technique indispensable in every type of research. Electron microscopy alone often provides enough information to solve given problems. In the field of the connective tissue matrix, knowledge of the molecular structure of collagen, pro teoglycans and elastin and their interaction has been to a large extent elucidated by electron microscopy. The field over which electron microscopy ranges in the investigation of the connective tissue matrix is so wide that the aim of this volume is to collect the main ultrastructural acquisitions disseminated in various journals and monographs in one book. The intent ofthis volume is to: (a) integrate different and new microscopic methods and review the results of such an integrative approach; (b) present a comprehensive ultrastructural account of selected aspects of the field; (c) point out gaps or controversial topics in our knowledge; (d) outline pertinent future research and expansion of the subject.

Author : E. Bonucci,P. Motta
Publisher : Springer Science & Business Media
Page : 302 pages
File Size : 42,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461314875

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Ultrastructure of Skeletal Tissues by E. Bonucci,P. Motta Pdf

The calcified tissues have fundamental functions in the biology of organisms, not only because their strength, solidity, and elasticity permit movement and mechanical activities, and protect soft tissues against traumatic forces, but also on account of their role in mineral homeostasis. For this reason, extensive investigation in the last 30 years has provided much to explain the complex chemical and physical processes occurring in cells and matrices composing the skeleton, and their alterations in pathological conditions. The use of ultrastructural methods such as immunocytochemistry, scanning and transmission electron microscopy, cytoautoradiography, freeze/fracture etching, high voltage, etc. has proven to be of great value when applied to cells and matrix components of bone and cartilage, in spite of the technical difficulties due to the hardness of these tissues. However, available information on this subject is disseminated in a variety of scientific and medical articles. This volume is an attempt to collect together the most significant data on the ultrastructure of cartilage and bone in normalcy and pathology. Obviously, it cannot be a complete report of all these data, its principal aim being that of: a) giving a comprehensive statement of the results concerning the basic structures common to these tissues, especially collagen fibrils, noncollagenous proteins, and proteoglycans, and their relationships with the mineral substance (for which another volume of this series can also be consulted; see Ruggeri A. , Motta P. M. (eds.

Author : Laszlo Modis
Publisher : CRC Press
Page : 295 pages
File Size : 44,7 Mb
Release : 2018-05-04
Category : Science
ISBN : 9781351083737

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Organization of the Extracellular Matrix by Laszlo Modis Pdf

This book describes analysis techniques and results of topics such as physical backgrounds, chemical backgrounds, and principal methods of topo-optical reactions used in ultrastructure research of the ECM; orientation patterns of GAGs and collagen in different tissues/cartilage, cornea, kidney basement membranes, and skin; factors involved in the formation of submicroscopically ordered matrix structure; and cell-matrix interactions, including cytoskeleton-cell-membrane-matrix relationships. A summarization of the advantages and limitations of polarization microscopy compared to electron microscopy in ultracellular research is also included. Cell biologists, histologists, pathologists, and biochemists in connective tissue research will find this book to be an invaluable reference tool.

Author : Margit Pavelka,Jürgen Roth
Publisher : Springer Science & Business Media
Page : 340 pages
File Size : 44,6 Mb
Release : 2005-12-05
Category : Medical
ISBN : 9783211263921

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Functional Ultrastructure by Margit Pavelka,Jürgen Roth Pdf

The period between 1950 and 1980 were the golden It also provides unique insights into how pathological years of transmission electron microscopy and pro- processes affect cell organization. duced a plethora of new information on the structure of This information is vital to current work in which cells that was coupled to and followed by biochemical the emphasis is on integrating approaches from p- and functional studies. TEM was king and each micro- teomics, molecular biology, molecular imaging and graph of a new object produced new information that physiology, and pathology to understand cell functions led to new insights on cell and tissue organization and and derangements in disease. In this current era, there is their functions. The quality of data represented by the a growing tendency to substitute modern light mic- images of cells and tissues had been perfected to a very scopic techniques for electron microscopy because it is high level by the great microscopists of the era including less technically demanding and is more readily available Palade, Porter, Fawcett, Sjostrand, Rhodin and many to researchers. This atlas reminds us that the infor- others. At present, the images that we see in leading tion obtained by electron microscopy is invaluable and journals for the most part do not reach the same techni- has no substitute.

Author : Edward F. Delagi
Publisher : Charles C. Thomas Publisher
Page : 580 pages
File Size : 45,5 Mb
Release : 1976
Category : Medical
ISBN : UOM:39015000862626

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The Ultrastructure of Collagen by Edward F. Delagi Pdf

Author : Isidore Gersh
Publisher : Elsevier
Page : 264 pages
File Size : 46,6 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780323158626

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Membranes, Mitochondria, and Connective Tissues by Isidore Gersh Pdf

Submicroscopic Cytochemistry, Volume II: Membranes, Mitochondria, and Connective Tissues presents laboratory findings and theoretical aspects of the cytochemistry of cellular membranes, mitochondria, and connective tissues. Emphasis is on the molecular and macromolecular organization of cellular membranes, along with the origin and distribution of the major macromolecular aggregates of connective tissue. This volume consists of 11 chapters and begins by discussing the results of cytochemical studies on lipid and protein components of membranes in acinar and hepatic cells of the murine pancreas. The following chapters focus on densitometric studies of lipid membranes in pancreatic acinar cells of the mouse; the distribution of lipids and proteins in mitochondria of hepatic and exocrine pancreatic cells of adult mice, and of nucleic acids in mitochondria of embryonic cells; and possible precursor granules in fibroblasts, chondrocytes, and osteoblasts. The distribution of DNA and of soluble and insoluble RNAs in chondrocytes of the epiphyseal plate of the rat tibia is also examined, along with vascularity in tendons of young rats. This monograph will be of interest to cytochemists, biochemists, and molecular biologists.

Author : David W. L. Hukins
Publisher : Wiley-VCH
Page : 266 pages
File Size : 40,7 Mb
Release : 1984
Category : Medical
ISBN : UOM:39015008746854

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Connective Tissue Matrix by David W. L. Hukins Pdf

Author : Keith R. Porter,Mary A. Bonneville
Publisher : Unknown
Page : 220 pages
File Size : 54,5 Mb
Release : 1973
Category : Medical
ISBN : UOM:39015013215614

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Fine Structure of Cells and Tissues by Keith R. Porter,Mary A. Bonneville Pdf

With the collaboration of Susan A. Badenhausen in transmission electron microscopy and Peter Andrews in scanning electron microscopy.

Author : E.D. Hay
Publisher : Springer Science & Business Media
Page : 478 pages
File Size : 47,5 Mb
Release : 2013-11-11
Category : Science
ISBN : 9781461537700

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Cell Biology of Extracellular Matrix by E.D. Hay Pdf

In the ten-year interval since the first edition of this volume went to press, our knowledge of extracellular matrix (ECM) function and structure has enor mously increased. Extracellular matrix and cell-matrix interaction are now routine topics in the meetings and annual reviews sponsored by cell biology societies. Research in molecular biology has so advanced the number of known matrix molecules and the topic of gene structure and regulation that we won dered how best to incorporate the new material. For example, we deliberated over the inclusion of chapters on molecular genetics. We decided that with judicious editing we could present the recent findings in molecular biology within the same cell biology framework that was used for the first edition, using three broad headings: what is extracellular matrix, how is it made, and what does it do for cells? Maintaining control over the review of literature on the subject of ECM was not always an easy task, but we felt it was essential to production of a highly readable volume, one compact enough to serve the the student as an introduction and the investigator as a quick update on graduate the important recent discoveries. The first edition of this volume enjoyed con hope the reader finds this edition equally useful. siderable success; we D. Hay Elizabeth vii Contents Introductory Remarks 1 Elizabeth D. Hay PART I. WHAT IS EXTRACELLULAR MATRIX? Chapter 1 Collagen T. F. Linsenmayer 1. Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 2. The Collagen Molecule . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 2. 1. Triple-Helical Domain(s) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Author : Peter M. Royce,Beat Steinmann
Publisher : John Wiley & Sons
Page : 1201 pages
File Size : 49,9 Mb
Release : 2003-04-14
Category : Medical
ISBN : 9780471461173

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Connective Tissue and Its Heritable Disorders by Peter M. Royce,Beat Steinmann Pdf

The Second Edition of Connective Tissue and Its Heritable Disorders: Molecular, Genetic, and Medical Aspects is the definitive reference text in its field, with over 40% more pages on the nature, diagnosis, and treatment of disease than its predecessor. Collecting new research on disorders detailed in the first edition as well as on those previously excluded, editors Peter Royce and Beat Steinmann provide the most up-to-date clinical and scientific information for medical specialists treating affected individuals. Features of this revised and updated volume include detailed reviews of the clinical diagnosis, mode of inheritance, risk of recurrence, and prenatal diagnosis of each inherited connective tissue disorder; a thorough description of the morphology of connective tissues; a completely updated and revised section on the biology of the extracellular matrix; and the addition of syndromes such as craniosyntosis, and disorders of sulfate metabolism.

Author : Laszlo Modis
Publisher : CRC Press
Page : 331 pages
File Size : 55,7 Mb
Release : 2018-05-04
Category : Science
ISBN : 9781351092180

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Organization of the Extracellular Matrix by Laszlo Modis Pdf

This book describes analysis techniques and results of topics such as physical backgrounds, chemical backgrounds, and principal methods of topo-optical reactions used in ultrastructure research of the ECM; orientation patterns of GAGs and collagen in different tissues/cartilage, cornea, kidney basement membranes, and skin; factors involved in the formation of submicroscopically ordered matrix structure; and cell-matrix interactions, including cytoskeleton-cell-membrane-matrix relationships. A summarization of the advantages and limitations of polarization microscopy compared to electron microscopy in ultracellular research is also included. Cell biologists, histologists, pathologists, and biochemists in connective tissue research will find this book to be an invaluable reference tool.

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 43,6 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf

Author : Peter D. Yurchenco
Publisher : Academic Press
Page : 483 pages
File Size : 43,5 Mb
Release : 2013-10-22
Category : Science
ISBN : 9781483289427

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Extracellular Matrix Assembly and Structure by Peter D. Yurchenco Pdf

The complex and critical process of extracellular matrix (ECM) assembly is described in this book. Assembly may involve molecules interacting with molecules of the same matrix class, such as in collagen, or interactions between different ECM molecules, such as in basement membranes. The text shows how this is driven by structural information within the matrix monomer. This information will be of interest to cell, developmental, and molecular biologists, biochemists, biophysicists, and biomedical researchers involved in macromolecular assembly, biological macromolecules, and extracellular matrix. Addresses assembly of most of the known classes of extracellular matrix macromolecules Discusses higher order structures produced by ECM Gives important concepts in ECM and cell-matrix interactions, Protein structure and protein-protein interactions, Development and tissue remodeling

Author : P. Motta
Publisher : Springer Science & Business Media
Page : 258 pages
File Size : 48,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461306832

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Ultrastructure of Smooth Muscle by P. Motta Pdf

Recent advances in electron microscopy have opened up new dimensions and perspectives in the field of morphology, and these are presently being integrated with biochemical and physiopathological phenomena occurring in cells, tissues, and organs. Methods such as freeze-fracture, freeze-etching, scanning, and high-voltage electron microscopy have contributed immensely to this progress, as well as to the study of smooth muscle tissue and contractile cells in general. The articles composing this book have been selected and edited with the purpose of updating and reviewing the most important aspects of smooth muscle cells as revealed by the integration of these submicroscopic techniques. The chapters of this volume have been prepared by some of the most authoritative experts in the discipline. Therefore each article not only offers the reader a concise review of the specific topic, but also seeks to highlight areas that require further investigation. Much of the volume is presented in an illustrative format so as to emphasize the remarkable results obtainable by the combination of the aforementioned methods, which allow a better appreciation of smooth muscle structure and ultrastructure. This volume, like others in the series, is intended not only for researchers in the field, but also for graduate students of histology, embryology, anatomy, physiology, and pathology in both medical and veterinary colleges. My hope is that this book will prove to be a valuable academic resource to the audience of the world in this fascinating and expanding field.

Author : G. Familiari,Sayoko Makabe,P. Motta
Publisher : Springer Science & Business Media
Page : 330 pages
File Size : 45,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461539445

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Ultrastructure of the Ovary by G. Familiari,Sayoko Makabe,P. Motta Pdf