Use Of Biomarkers For Environmental Quality Assessment
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Use of Biomarkers for Environmental Quality Assessment by Jean-Claude Amiard,Thierry Caquet,Laurent Lagadic Pdf
This work is primarily designed for any person or organization in charge of assessment of the quality of natural resources and of pollution prevention.
The aim of this book is to provide the reader with a basic understanding of the use of bioindicators both in assessing environmental quality and as a means of support in environmental impact assessment (EIA) procedures.
Biological markers used to assess the effects of environmental pollution have attracted considerable attention from regulatory agencies and are currently under evaluation at a number of research facilities throughout the world. However promising a biomarker-based biomonitoring approach may be, the development of this concept is complicated by a range of technical issues. This book provides a conceptional framework for research and application of biomarkers. International experts on biomonitoring have formulated a unified strategy for the development and validation of biomarkers in assessing environmental health as well as appropriate protocols for their implementation and interpretation in a biological monitoring program.
Use of Biomarkers in Assessing Health and Environmental Impacts of Chemical Pollutants by Curtis C. Travis Pdf
Biological markers (biomarkers) are useful tools for understanding the nature and extent of human exposure and risk from environmental toxicants. Biomarkers are classified into three basic categories: exposure, effect, or susceptibility. A marker of exposure is the product of the interaction between a target cell or molecule and a foreign substance (NAS, 1989). These markers can be used to determine the biologically effective dose necessary to elicit a particular physiological change in an organism. A marker of effect is a biochemical or physiological change in an organism that can predict the onset of adverse health effects resulting from a given exposure. Lastly, markers of susceptibility act as indicators of an inherent or acquired tendency of an organism to experience an adverse health effect (NAS, 1989). These markers are already used to detect a variety of diseases and show great promise for developing a better understanding of the mechanicisms of disease. Additionally, biomarkers can be used to establish a more rational basis for quantitative risk extrapolation between species, as weIl as to obtain more precise estimates of the time of critical exposure. These markers can also prove helpful in identifying potentially damaging exposures before the onset of adverse health effects. Biomarkers serve as a valuable exposure assessment tool because they take into account exposure from all routes and integrate exposure from all sources. They have the potential to yield better risk estimates than current monitoring and modeling protocols. In lune 1992, Dr. Travis and Dr.
Bioindicators and Biomarkers of Environmental Pollution and Risk Assessment by Jamil Kaiser Pdf
Provides the reader with an overview of the variety of animal and plants that are available for use as environmental monitors. The author emphasizes that the use of a single species of target bioindicator is not appropriate or scientifically sound for the monitoring of several toxic pollutants.
Medical Research Council (Great Britain). Institute for Environment and Health
Author : Medical Research Council (Great Britain). Institute for Environment and Health Publisher : Unknown Page : 124 pages File Size : 54,5 Mb Release : 1996 Category : Air ISBN : IND:30000054045798
IEH Report on the Use of Biomarkers in Environmental Exposure Assessment by Medical Research Council (Great Britain). Institute for Environment and Health Pdf
National Research Council,Division on Earth and Life Studies,Board on Environmental Studies and Toxicology,Committee on Human Biomonitoring for Environmental Toxicants
Author : National Research Council,Division on Earth and Life Studies,Board on Environmental Studies and Toxicology,Committee on Human Biomonitoring for Environmental Toxicants Publisher : National Academies Press Page : 316 pages File Size : 40,5 Mb Release : 2006-10-30 Category : Science ISBN : 9780309133906
Human Biomonitoring for Environmental Chemicals by National Research Council,Division on Earth and Life Studies,Board on Environmental Studies and Toxicology,Committee on Human Biomonitoring for Environmental Toxicants Pdf
Biomonitoring—a method for measuring amounts of toxic chemicals in human tissues—is a valuable tool for studying potentially harmful environmental chemicals. Biomonitoring data have been used to confirm exposures to chemicals and validate public health policies. For example, population biomonitoring data showing high blood lead concentrations resulted in the U.S. Environmental Protection Agency's (EPA's) regulatory reduction of lead in gasoline; biomonitoring data confirmed a resultant drop in blood lead concentrations. Despite recent advances, the science needed to understand the implications of the biomonitoring data for human health is still in its nascent stages. Use of the data also raises communication and ethical challenges. In response to a congressional request, EPA asked the National Research Council to address those challenges in an independent study. Human Biomonitoring for Environmental Chemicals provides a framework for improving the use of biomonitoring data including developing and using biomarkers (measures of exposure), research to improve the interpretation of data, ways to communicate findings to the public, and a review of ethical issues.
Biomarkers: A Pragmatic Basis for Remediation of Severe Pollution in Eastern Europe by David B. Peakall,Colin H. Walker,Pawel Migula Pdf
Many areas of Eastern Europe have been polluted to an extent unknown in the West. Four such sites - Kola Peninsula, northern Bohemia, upper Vistula Basin, and Katowice - have been identified and detailed accounts of the pollution at these sites are given. The current status of the use of biomarkers in hazard assessment is given by several scientists from NATO countries. Four working groups, comprising scientists working on the polluted sites and western scientists with expertise in biomarkers, examine the use of biomarkers to assess the environmental health of each of these areas and make recommendations on the future direction of remedial action in these areas.
Ecological Biomarkers by Claude Amiard-Triquet,Jean-Claude Amiard,Philip S. Rainbow Pdf
Does a change, which affects a few biological macro-molecules, some cells, or a few individuals within a population, have any ecological significance that would allow the prediction of deleterious effects at higher levels of biological organization, namely the population, community, and ultimately the ecosystem? With contributions from experts in t
Biomarkers in Environmental and Human Health Biomonitoring by Ritu Mishra,Sughosh Madhav,Rahul Kumar Dhaka,Parveen Garg Pdf
Biomarkers in Environmental and Human Health Biomonitoring: An Integrated Perspective provides a holistic view of the biomonitoring of environmental degradation, accumulated toxicity, and associated human health concerns. The book incorporates theoretical and practical aspects of the biomonitoring of environmental pollution and the health surveillance of ecological communities using samples from living organisms which are analyzed for contaminants and toxin levels. In the first half, the book provides a general overview if the different types of biomarkers, their significance as bioindicators for contaminants and detection of toxicity, as well as how they can be utilized in the restoration of degraded ecosystems. The second half of the book discusses molecular biomarkers and how they are used as diagnostic and prognostic tools for pollution monitoring. It also reviews analytical tools used to validate the biomarkers in the detection and monitoring of pollution and disease. Finally, the book delves into how novel approaches like genetic ecotoxicology; Big Data, and artificial intelligence calculates the potential consequences of environmental pollution on the ecosystems and on human health. Covers the fundamentals, types, significance, and limitations of biomarkers Examines various types of plants, animals, and secondary metabolites in identifying and monitoring toxicity in different ecosystems and potential impacts on health Reviews biomarker-based and bioinformatic tools in the detection and monitoring of environmental pollution and associated human health
Institute of Medicine,Board on Health Promotion and Disease Prevention,Committee to Assess the Science Base for Tobacco Harm Reduction
Author : Institute of Medicine,Board on Health Promotion and Disease Prevention,Committee to Assess the Science Base for Tobacco Harm Reduction Publisher : National Academies Press Page : 657 pages File Size : 49,5 Mb Release : 2001-10-17 Category : Medical ISBN : 9780309072823
Clearing the Smoke by Institute of Medicine,Board on Health Promotion and Disease Prevention,Committee to Assess the Science Base for Tobacco Harm Reduction Pdf
Despite overwhelming evidence of tobacco's harmful effects and pressure from anti-smoking advocates, current surveys show that about one-quarter of all adults in the United States are smokers. This audience is the target for a wave of tobacco products and pharmaceuticals that claim to preserve tobacco pleasure while reducing its toxic effects. Clearing the Smoke addresses the problems in evaluating whether such products actually do reduce the health risks of tobacco use. Within the context of regulating such products, the committee explores key questions: Does the use of such products decrease exposure to harmful substances in tobacco? Is decreased exposure associated with decreased harm to health? Are there surrogate indicators of harm that could be measured quickly enough for regulation of these products? What are the public health implications? This book looks at the types of products that could reduce harm and reviews the available evidence for their impact on various forms of cancer and other major ailments. It also recommends approaches to governing these products and tracking their public health effects. With an attitude of healthy skepticism, Clearing the Smoke will be important to health policy makers, public health officials, medical practitioners, manufacturers and marketers of "reduced-harm" tobacco products, and anyone trying to sort through product claims.
Biomarkers of Environmental Contamination by 0 McCarthy Pdf
How can biological markers help assess and predict human health risks? Find out the answers to this question and others in this timely new book examining the use of biological markers in animals and plants for evaluating the ecological and health effects of environmental contamination. The book explains the concept of environmental sentinels, presents example of field studies and discusses the utility of biomarkers within a risk analysis paradigm. Anyone who needs to know how to assess and predict environmental contamination should consider this book essential reading.