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Using Optical Probes To Study The Behavior Of Voltage Gated Ion Channels Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Using Optical Probes To Study The Behavior Of Voltage Gated Ion Channels book. This book definitely worth reading, it is an incredibly well-written.
Author : Albert Cha
Publisher : Unknown
Page : 252 pages
File Size : 48,9 Mb
Release : 1999
Category : Electronic
ISBN : UCLA:L0078710324
Author : Wim E. Crusio,R.T. Gerlai
Publisher : Elsevier
Page : 962 pages
File Size : 42,8 Mb
Release : 1999-10-18
Category : Psychology
ISBN : 0080536867
The book gives a broad overview of recombinant DNA techniques for the behavioral neuroscientist, with illustrative examples of applications. Species covered include rodents (mainly mice), Drosophila melanogaster, Caenorhabditis elegans and Danio rerio. Experimental techniques required to characterize the behavioral phenotypes of mutant animals is provided. Several aspects of novel molecular-genetic techniques are overviewed and possible research strategies are explained. The sections of the book start with general descriptions of techniques followed by illustrative examples. It is divided into six sections. Section 1, bioinformatics and genomics research. Section 2, top-down strategies, where the researcher starts with the phenotype and then analyzes the associated genes; bottom-up strategies, where the physiological chain leading to a phenotype is analyzed starting from the gene product. Section 3, transgenic approaches in rodents including overexpressing foreign genes and gene-targeting; systemic manipulation approaches directly targeting the central nervous system and methods used with invertebrates. Section 4, methods used to evaluate relevant behavioral phenotypes, including learning and aggression. Section 5, examples on molecular brain research in man. Section 6, ethical aspects of research in this field.
Author : University of California, Los Angeles. Brain Research Institute
Publisher : Unknown
Page : 442 pages
File Size : 53,9 Mb
Release : 1999
Category : Brain
ISBN : UCBK:C077320903
Author : Anonim
Publisher : Unknown
Page : 846 pages
File Size : 49,7 Mb
Release : 2006
Category : Dissertations, Academic
ISBN : STANFORD:36105123430014
Author : Robert T. Gerlai
Publisher : Academic Press
Page : 710 pages
File Size : 49,9 Mb
Release : 2018-04-24
Category : Mathematics
ISBN : 9780128041161
Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research presents the most exciting molecular and recombinant DNA techniques used in the analysis of brain function and behavior, a critical piece of the puzzle for clinicians, scientists, course instructors and advanced undergraduate and graduate students. Chapters examine neuroinformatics, genetic and neurobehavioral databases and data mining, also providing an analysis of natural genetic variation and principles and applications of forward (mutagenesis) and reverse genetics (gene targeting). In addition, the book discusses gene expression and its role in brain function and behavior, along with ethical issues in the use of animals in genetics testing. Written and edited by leading international experts, this book provides a clear presentation of the frontiers of basic research as well as translationally relevant techniques that are used by neurobehavioral geneticists. Focuses on new techniques, including electrocorticography, functional mapping, stereo EEG, motor evoked potentials, optical coherence tomography, magnetoencephalography, laser evoked potentials, transmagnetic stimulation, and motor evoked potentials Presents the most exciting molecular and recombinant DNA techniques used in the analysis of brain function and behavior Written and edited by leading international experts
Author : Anonim
Publisher : Unknown
Page : 834 pages
File Size : 41,8 Mb
Release : 1987
Category : Medicine
ISBN : UOM:39015011769695
Author : Gildas Loussouarn,Mounir Tarek
Publisher : Frontiers E-books
Page : 211 pages
File Size : 45,8 Mb
Release : 2024-06-16
Category : Electronic
ISBN : 9782889191154
Voltage-gated ion channels are transmembrane proteins in which at least one gate is controlled by the transmembrane potential. They are frequently very selectively permeable to sodium (Nav channels), potassium (Kv channels) or calcium (Cav channels) ions. Depending on the channels, opening of the activation gate is triggered by membrane depolarization (Kv, Nav and Cav channels) or hyperpolarization (HCN channels for instance). In addition, in many voltage-gated channels, a so-called inactivation gate is also present. Compared to the activation gate, the latter is oppositely coupled to the potential: In Kv, Nav and Cav channels, upon membrane depolarization, the inactivation gate closes whereas the activation gate opens. Depending on the cell types in which they are expressed and their physiological role, various voltage-dependent channels can be characterized by their conductance, ion selectivity, pharmacology and voltage-sensitivity. These properties are mainly dictated by the amino-acids sequence and structure of the pore forming subunit(s), presence of accessory subunit(s), membrane composition, intra- and extracellular ions concentration. Noteworthy, despite a profound variety of these ion channels characteristics, it seems that most of them obey to the same global, four-fold structure now obtained by several X-ray crystallography experiments. Given the wealth of electrophysiological, biochemical, optical, and structural data regarding ion channels voltage-dependency, we decided to put together in this e-book, up to date reviews describing the molecular details of these complex voltage-gated channels.
Author : Peter Hegemann,Stephan Sigrist
Publisher : Walter de Gruyter
Page : 240 pages
File Size : 40,7 Mb
Release : 2013-08-28
Category : Science
ISBN : 9783110270723
Optogenetics combines genetic engineering with optics to observe and control the function of cells using light, with clinical implications for restoration of vision and treatment of neurological diseases. As a new discipline much of the basic science and methods are currently under investigation and active development, thus there is a strong need for introductory literature in this field. This graduate level textbook provides an overview of the field of optogenetics in 5 concise chapters: Optogenetic tools, Applications in cellular systems, Mapping neuronal networks, Clinical applications and Restoration of vision and hearing. The concept and content was developed with top international researchers and students at a prestigious Dahlem Conference workshop.
Author : Donald Cheng
Publisher : Springer Science & Business Media
Page : 495 pages
File Size : 50,9 Mb
Release : 2013-11-11
Category : Medical
ISBN : 9781461593379
This book is a collection of up-to-date research reviews dealing with various aspects of the structure and function of excitable cells. Its overall objective is to further the search for a better understanding of the mechanism of excitation on a structural and physicochemical basis. The chapters are written by active investigators from a variety of disciplines, repre senting many different points of view. Their complementary fields of expertise give this book the rare feature of extraordinary breadth. Excitability is a fundamental property of many biological systems. The mechanisms by which nerve impulses are initiated and propagated, and by which rhythmical activities are produced in nerve, muscle, and cardiac cells, can be fully elucidated only when the process of excitation is derived from fundamental principles applied to known structural forms, at both the macroscopic and the molecular level. The problems of excitation are complex, requiring knowledge of many aspects of cells, including their morphology, elec trobiology, chemical physics, and biochemistry.
Author : Gerard Marriott
Publisher : Academic Press
Page : 584 pages
File Size : 47,8 Mb
Release : 1998-06-22
Category : Medical
ISBN : UVA:X004242750
The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. More than 285 volumes have been published (all of them still in print) and much of the material is relevant even today--truly an essential publication for researchers in all fields of life sciences.
Author : Ming Lei,Christopher Huang
Publisher : Frontiers Media SA
Page : 147 pages
File Size : 54,9 Mb
Release : 2020-06-25
Category : Electronic
ISBN : 9782889638031
Author : Osei Kwame Asamoah
Publisher : Unknown
Page : 350 pages
File Size : 42,9 Mb
Release : 2004
Category : Electronic
ISBN : UCLA:L0089499123
Author : Somnath Mukhopadhyay,Sunita Sarkar,Paramartha Dutta,Jyotsna Kumar Mandal,Sudipta Roy
Publisher : Springer Nature
Page : 460 pages
File Size : 41,6 Mb
Release : 2022-07-21
Category : Computers
ISBN : 9783031107665
This book constitutes the refereed proceedings of the 4th International Conference on Computational Intelligence, Communications, and Business Analytics, CICBA 2022, held in Silchar, India, in January 2022. The 21 full papers and 13 short papers presented in this volume were carefully reviewed and selected from 107 submissions. The papers are organized in topical sections on computational intelligence; computational intelligence in communication; and computational intelligence in analytics.
Author : Alan Longstaff,Michael R. Ronczkowski
Publisher : Taylor & Francis
Page : 463 pages
File Size : 48,5 Mb
Release : 2011-03-16
Category : Medical
ISBN : 9781136667657
BIOS Instant Notes in Neuroscience, 3rd edition, has been reorganized and some detail removed from both text and figures in order to make it a more effective resource for students. While concentrating on core themes, areas where there have been significant advances, especially learning, memory, and cognition, have been thoroughly updated. There will be a separate section on methods allowing students to separate results from methodology.
Author : Enric Brillas,Carlos Alberto Mart¿nez-Huitle
Publisher : John Wiley & Sons
Page : 713 pages
File Size : 51,8 Mb
Release : 2011-08-24
Category : Science
ISBN : 9781118062357
The book gives an overview on the current development status of synthetic diamond films and their applications. Its initial part is devoted to discuss the different types of conductive diamond electrodes that have been synthesized, their preparation methods, and their chemical properties and characterization. The electrochemical properties of diamond films in different scientific areas, with special attention in electroanalysis, are further described. Different strategies to modify these electrodes are also discussed as important technologies with ability to change their electrochemical characteristics for a more specific electroanalytical use. The second part of the book deals with practical applications of diamond electrodes to the industry, organic electrosynthesis, electrochemical energy technology, and biotechnology. Special emphasis is made on the properties of these materials for the production of strong oxidizing species allowing the fast mineralization of organics and their use for water disinfection and decontamination. Recent biotechnological development on biosensors, microelectrodes, and nanostructured electrodes, as well as on neurochemistry, is also presented. The book will be written by a large number of internationally recognized experts and comprises 24 chapters describing the characteristics and theoretical fundaments of the different electrochemical uses and applications of synthetic diamond films.
