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Author : Donald Cheng
Publisher : Unknown
Page : 516 pages
File Size : 42,5 Mb
Release : 2014-01-15
Category : Electronic
ISBN : 1461593387
Author : Donald Cheng
Publisher : Springer Science & Business Media
Page : 495 pages
File Size : 41,8 Mb
Release : 2013-11-11
Category : Medical
ISBN : 9781461593379
This book is a collection of up-to-date research reviews dealing with various aspects of the structure and function of excitable cells. Its overall objective is to further the search for a better understanding of the mechanism of excitation on a structural and physicochemical basis. The chapters are written by active investigators from a variety of disciplines, repre senting many different points of view. Their complementary fields of expertise give this book the rare feature of extraordinary breadth. Excitability is a fundamental property of many biological systems. The mechanisms by which nerve impulses are initiated and propagated, and by which rhythmical activities are produced in nerve, muscle, and cardiac cells, can be fully elucidated only when the process of excitation is derived from fundamental principles applied to known structural forms, at both the macroscopic and the molecular level. The problems of excitation are complex, requiring knowledge of many aspects of cells, including their morphology, elec trobiology, chemical physics, and biochemistry.
Author : F. A. Miles
Publisher : Elsevier
Page : 156 pages
File Size : 49,6 Mb
Release : 2013-09-17
Category : Science
ISBN : 9781483183008
Monographs in Modern Biology for Upper School and University Courses: Excitable Cells focuses on the fundamental nature of the signals carried in the nervous system, including nervous activity, synapses, and membrane permeability. The publication first elaborates on the elements of structure and function in the nervous system and resting nerve. Discussions focus on neuron, synapse, effect of changes in membrane permeability on membrane potential, recording nervous activity, movement of ions through solutions and membranes, and permeability of the resting membrane. The text then takes a look at the nerve impulse, including permeability changes associated with the nerve impulse, voltage clamp studies, and electrical model of the nerve membrane. The manuscript examines input signal and synapse. Topics include receptor discharge, generator potential, coding of the input message, frog neuromuscular junction, functional aspects of the vertebrate neuromuscular junction, nervous control of crustacean muscle, and central synapses. The publication is a dependable source material for biologists and readers interested in pursuing studies on excitable cells.
Author : Juliusz Ashot Kozak,James W. Putney, Jr.
Publisher : CRC Press
Page : 343 pages
File Size : 54,9 Mb
Release : 2017-07-14
Category : Science
ISBN : 9781498752732
Calcium Entry Channels in Non-Excitable Cells focuses on methods of investigating the structure and function of non-voltage gated calcium channels. Each chapter presents important discoveries in calcium entry pathways, specifically dealing with the molecular identification of store-operated calcium channels which were reviewed by earlier volumes in the Methods in Signal Transduction series. Crystallographic and pharmacological approaches to the study of calcium channels of epithelial cells are also discussed. Calcium ion is a messenger in most cell types. Whereas voltage gated calcium channels have been studied extensively, the non-voltage gated calcium entry channel genes have only been identified relatively recently. The book will fill this important niche.
Author : David J. Aidley
Publisher : Cambridge University Press
Page : 496 pages
File Size : 51,8 Mb
Release : 1998-09-03
Category : Medical
ISBN : 0521574218
The fourth edition of this highly successful text has been extensively revised and restructured to take account of the many recent advances in the subject and bring it right up to date. The classic observations of recent years can now be interpreted with the powerful new techniques of molecular biology. Consequently there is much new material throughout the book, including many new illustrations and extensive references to recent work. Its essential philosophy remains the same, though: fundamental concepts are clearly explained, and key experiments are examined in some detail. This textbook will be used by students of physiology, neuroscience, cell biology and biophysics. Specializing undergraduates and graduates as well as lecturers and researchers will find the text thorough and clearly written.
Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 45,8 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181
Author : J. Salánki
Publisher : Elsevier
Page : 338 pages
File Size : 53,9 Mb
Release : 2013-10-22
Category : Science
ISBN : 9781483189949
Advances in Physiological Sciences, Volume 3: Physiology of Non-Excitable Cells is a collection of papers presented at the 28th International Congress of Physiology, held in Budapest on July 13-19, 1980. This book is organized into five parts encompassing 36 chapters that cover the various physiological aspects of non-excitable cells and neuronal membranes. The first two parts describe cellular models of iso-osmotic and epithelial transport. The third part highlights the relationship between cell transport and cellular metabolism. This part also deals with the genetic and hormonal control of cellular transport, as well as the lipoprotein synthesis and secretion by hepatocyte. The fourth part explores cell-to-cell communication through junctional membrane channels and calmodulin. The fifth part examines the temporal structure of biological systems in the sub-second time domains. This book will be of value to physiologists, cell biologists, researchers, and biology students.
Author : Thomas E. Andreoli,Darrell D. Fanestil,Joseph F. Hoffman,Stanley G. Schultz
Publisher : Springer Science & Business Media
Page : 397 pages
File Size : 41,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461319436
Membrane Physiology (Second Edition) is a soft-cover book containing portions of Physiology of Membrane Disorders (Second Edition). The parent volume contains six major sections. This text encompasses the first three sections: The Nature of Biological Membranes, Methods for Studying Membranes, and General Problems in Membrane Biology. We hope that this smaller volume will be helpful to individuals interested in general physiology and the methods for studying general physiology. THOMAS E. ANDREOLI JOSEPH F. HOFFMAN DARRELL D. FANESTIL STANLEY G. SCHULTZ vii Preface to the Second Edition The second edition of Physiology of Membrane Disorders represents an extensive revision and a considerable expansion of the first edition. Yet the purpose of the second edition is identical to that of its predecessor, namely, to provide a rational analysis of membrane transport processes in individual membranes, cells, tissues, and organs, which in tum serves as a frame of reference for rationalizing disorders in which derangements of membrane transport processes playa cardinal role in the clinical expression of disease. As in the first edition, this book is divided into a number of individual, but closely related, sections. Part V represents a new section where the problem of transport across epithelia is treated in some detail. Finally, Part VI, which analyzes clinical derangements, has been enlarged appreciably.
Author : Bertil Hille
Publisher : Sinauer Associates, Incorporated
Page : 632 pages
File Size : 41,7 Mb
Release : 1992
Category : Excitable membranes
ISBN : UOM:39015024124383
This new, fully revised and expanded edition of Ionic Channels of Excitable Membranes includes new chapters on fast chemical synapses, modulation through G protein coupled receptors and second messenger systems, molecules cloning, site directed mutagenesis, and cell biology. It begins with the classical biophysical work of Hodgkin and Huxley and then weaves a description of the known ionic channels together with their biological functions. The book continues by developing the physical and molecular principles needed for explaining permeation, gating, pharmacological modification, and molecular diversity, and ends with a discussion of channel evolution. Ionic Channels of Excitable Membranes is written to be accessible and interesting to biological and physical scientists of all kinds.
Author : Peter C. Ruben
Publisher : Springer Science & Business Media
Page : 295 pages
File Size : 55,5 Mb
Release : 2014-04-15
Category : Medical
ISBN : 9783642415883
A number of techniques to study ion channels have been developed since the electrical basis of excitability was first discovered. Ion channel biophysicists have at their disposal a rich and ever-growing array of instruments and reagents to explore the biophysical and structural basis of sodium channel behavior. Armed with these tools, researchers have made increasingly dramatic discoveries about sodium channels, culminating most recently in crystal structures of voltage-gated sodium channels from bacteria. These structures, along with those from other channels, give unprecedented insight into the structural basis of sodium channel function. This volume of the Handbook of Experimental Pharmacology will explore sodium channels from the perspectives of their biophysical behavior, their structure, the drugs and toxins with which they are known to interact, acquired and inherited diseases that affect sodium channels and the techniques with which their biophysical and structural properties are studied.
Author : J. Gordon Betts,Peter DeSaix,Jody E. Johnson,Oksana Korol,Dean H. Kruse,Brandon Poe,James A. Wise,Mark Womble,Kelly A. Young
Publisher : Unknown
Page : 0 pages
File Size : 45,9 Mb
Release : 2013-04-25
Category : Electronic
ISBN : 1947172808
Author : Jeffrey L. Noebels,Massimo Avoli
Publisher : OUP USA
Page : 1258 pages
File Size : 44,7 Mb
Release : 2012-06-29
Category : Medical
ISBN : 9780199746545
Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.
Author : Stanley A. Briller,Hadley L. Conn, Jr.
Publisher : University of Pennsylvania Press
Page : 376 pages
File Size : 42,5 Mb
Release : 2017-04-10
Category : Science
ISBN : 9781512814798
This book is a volume in the Penn Press Anniversary Collection. To mark its 125th anniversary in 2015, the University of Pennsylvania Press rereleased more than 1,100 titles from Penn Press's distinguished backlist from 1899-1999 that had fallen out of print. Spanning an entire century, the Anniversary Collection offers peer-reviewed scholarship in a wide range of subject areas.
Author : Greg Conradi Smith
Publisher : Cambridge University Press
Page : 395 pages
File Size : 52,8 Mb
Release : 2019-03-14
Category : Mathematics
ISBN : 9781107005365
What every neuroscientist should know about the mathematical modeling of excitable cells, presented at an introductory level.
Author : Gonzalo Alarcón,Antonio Valentín
Publisher : Cambridge University Press
Page : 641 pages
File Size : 43,5 Mb
Release : 2012-04-26
Category : Medical
ISBN : 9780521691581
Covers all aspects of epilepsy, from basic mechanisms to diagnosis and management, as well as legal and social considerations.