Uveal Melanoma

Author : Eric H. Bernicker
Publisher : Springer Nature
Page : 229 pages
File Size : 47,5 Mb
Release : 2021-08-03
Category : Medical
ISBN : 9783030781170

Get Book

Uveal Melanoma by Eric H. Bernicker Pdf

This book provides a comprehensive examination of uveal melanoma, a rare neoplasm that carries a very high mortality and whose natural history makes it fairly unique among adult tumors. Split into three sections, this book explores the basic science behind the disease and inherited genetic syndromes that predispose some patients, as well as the pathology and use of gene expression profiling to determine risk of recurrence. It also focuses on the management of the primary tumor in the eye, including surgical intervention and lesion imaging. Elucidating treatment options for metastatic disease, the book reviews chemotherapy agents and immunotherapy approaches, as well as liver-directed therapies, cellular therapies, and various treatments after primary treatment but before the development of metastases. Uveal Melanoma: Biology and Management is the most up-to-date and comprehensive text devoted solely to this disease and will be useful to medical oncologists, ophthalmologists, radiation therapists, interventional radiologists, pathologists, molecular biologists and immunology researchers, as well as trainees in those fields.

Author : L. Desjardins,T. Kivelä,B.E. Damato,M.J. Jager
Publisher : Karger Medical and Scientific Publishers
Page : 196 pages
File Size : 43,6 Mb
Release : 2011-10-24
Category : Science
ISBN : 9783805597913

Get Book

Current Concepts in Uveal Melanoma by L. Desjardins,T. Kivelä,B.E. Damato,M.J. Jager Pdf

Uveal melanoma is an aggressive form of cancer that can involve the iris, the ciliary body, and/or the choroid, which is the main location of this tumor. Patients often wish to be informed about treatment choices and the results of different approaches. Important current clinical questions are whether a biopsy should be taken of choroidal melanomas, what should be done with this biopsy, and whether high-risk patients should be screened regularly.This volume describes the clinical characteristics of uveal melanoma along with the different current techniques available for treatment, such as radioactive plaque treatment, proton beam therapy, and local tumor resection. Furthermore, techniques for taking biopsies and characterizing biopsy material are demonstrated. Future therapies such as anti-VEGF treatment and options for the treatment of metastases are also discussed. Residents with an interest in ocular oncology, ophthalmologists or physicians dealing with uveal melanoma, as well as patients wishing to know more about this malignancy will find a topical update on uveal melanoma in this publication.

Author : Bita Esmaeli
Publisher : Springer Science & Business Media
Page : 483 pages
File Size : 44,6 Mb
Release : 2011-01-06
Category : Medical
ISBN : 9781441903747

Get Book

Ophthalmic Oncology by Bita Esmaeli Pdf

This book highlights the unique aspects of oncologic ophthalmology as a medical and surgical discipline practiced at a comprehensive cancer center. Multi-disciplinary management of ocular, orbital and adnexal cancers are highlighted using simple and tried-and-true algorithms. In addition, ocular problems caused as a direct result of cancer treatment are reviewed using illustrative photographs and case presentations. The content is provided by full-time ophthalmology faculty and fellows at M. D. Anderson Cancer Center. Experts in complementary disciplines such as ophthalmic pathology, dermatopathology, radiation oncology, radiology, and other surgical subspecialties have brought their unique perspective to each chapter. The book is abundant with clinical photographs as well as interesting case presentations that will help the clinician correctly diagnose cancers of the orbit, eye, and adnexal structures, initiate appropriate management, as well as recognize and treat common ocular complications of cancer therapy.

Author : J. G. Journée-de Korver
Publisher : Kugler Publications
Page : 122 pages
File Size : 52,5 Mb
Release : 1998
Category : Medical
ISBN : 9062991610

Get Book

Transpupillary Thermotherapy by J. G. Journée-de Korver Pdf

Author : M J Jager,J Y Niederkorn,B R Ksander
Publisher : CRC Press
Page : 280 pages
File Size : 41,9 Mb
Release : 2004-06
Category : Medical
ISBN : UOM:39015059179187

Get Book

Uveal Melanoma by M J Jager,J Y Niederkorn,B R Ksander Pdf

Presenting key research into the most common intraocular malignancy in adults, this text explores advances in the biology and metastasis of uveal melanoma, as well as the pathobiology of the disease and the need for further treatment options.

Author : Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland
Publisher : John Wiley & Sons
Page : 2008 pages
File Size : 51,6 Mb
Release : 2017-03-10
Category : Medical
ISBN : 9781119000846

Get Book

Holland-Frei Cancer Medicine by Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland Pdf

Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Author : Arun D. Singh,A. Linn Murphree,Bertil E. Damato
Publisher : Springer
Page : 225 pages
File Size : 44,7 Mb
Release : 2014-10-27
Category : Medical
ISBN : 9783662434512

Get Book

Clinical Ophthalmic Oncology by Arun D. Singh,A. Linn Murphree,Bertil E. Damato Pdf

Written by internationally renowned experts, Clinical Ophthalmic Oncology provides practical guidance and advice on the diagnosis and management of the complete range of ocular cancers. The book supplies all of the state-of-the-art knowledge required in order to identify these cancers early and to treat them as effectively as possible. Using the information provided, readers will be able to provide effective patient care using the latest knowledge on all aspects of ophthalmic oncology, to verify diagnostic conclusions based on comparison with numerous full-color clinical photographs, and to locate required information quickly owing to the clinically focused and user-friendly format. In this volume, all aspects of the diagnosis, histopathology, genetics and treatment of retinoblastoma are discussed in detail.

Author : Jerry A. Shields,Carol L. Shields
Publisher : Lippincott Williams & Wilkins
Page : 608 pages
File Size : 45,7 Mb
Release : 2015-08-10
Category : Medical
ISBN : 9781496321367

Get Book

Intraocular Tumors: An Atlas and Textbook by Jerry A. Shields,Carol L. Shields Pdf

For outstanding visual clarity in ocular diagnosis ... nothing else comes close. In this updated and revised third edition, world-renowned authorities at the Wills Eye Hospital provide outstanding guidance on recognition, evaluation, and treatment of ocular tumors, highlighted by more than 2,500 stunning photographs and surgical drawings. This unsurpassed ocular oncology resource is a comprehensive guide to the clinical features, diagnosis, management, and pathology of intraocular tumors and pseudotumors, depicting clinical variations, treatment, and histopathologic characteristics of the many varied benign and malignant lesions that affect the uveal tract, retina, and other intraocular structures. Now brought thoroughly up to date with recent clinical and scientific innovations, this unique volume has been greatly expanded with over 25% new material, and offers more high-quality images than any other text/atlas in the field. Presents each entity in an easy-to-follow format: a concise description with references on the left-hand page and six illustrations on the right-hand page. Depicts in precise photographic detail the gross and microscopic features that distinguish each condition, while professional drawings and intraoperative photographs demonstrate key surgical principles and procedures. Features numerous new references regarding diagnosis and treatment, as well as new scientific tables containing key information for your clinical practice. Features 25% new images, including panoramic images, surgical images, diagnostic testing images from multiple modalities, and updated OCT images with numerous enhanced depth imaging OCT (EDI-OCT). Covers new information on evolving conditions such as the management of choroidal nevus and melanoma with guidance for early detection using risk factors; information on the newest treatment for retinoblastoma with intra-arterial and intravenous chemotherapy; management of intraocular tumors with photodynamic therapy. Important new information on genetics of uveal melanoma, the implications of genetics, and treatment outcomes is described

Author : Daniel M. Albert,Arthur Polans
Publisher : CRC Press
Page : 525 pages
File Size : 47,7 Mb
Release : 2003-08-26
Category : Medical
ISBN : 9780824756314

Get Book

Ocular Oncology by Daniel M. Albert,Arthur Polans Pdf

Survival rates in cases of uveal melanoma and retinoblastoma - the leading intraocular malignancies in adults and children - may be high, but means of earlier diagnosis and improved treatment options are needed to preserve vision and prevent metastasis. This reference deals principally with the molecular biology and genetic factors which trigger an

Author : Jack J. Kanski,Brad Bowling
Publisher : Elsevier Health Sciences
Page : 931 pages
File Size : 48,6 Mb
Release : 2015-03-24
Category : Medical
ISBN : 9780702055744

Get Book

Kanski's Clinical Ophthalmology E-Book by Jack J. Kanski,Brad Bowling Pdf

Kanski’s Clinical Ophthalmology: A Systematic Approach is the classic specialty text providing the perfect ophthalmology foundation for trainees through to experienced practitioners. The famous visually dynamic and succinct format enables easy comprehension and focused guidance in the diagnosis and management of ophthalmic disorders. Build the ultimate foundation in ophthalmology with this market-leading resource. Benefit from guidance on examination, imaging, and the recognition of systemic conditions associated with ocular disease. Completely revised by award-winning ophthalmic educator Brad Bowling, the eighth edition reflects the latest advances, making this an indispensable resource to enhance learning, aid exam preparation and guide clinical practice. Designed for rapid reference and efficient recall, the concise but comprehensive chapters use crisp targeted text, bulleted lists, tables, and visual aids to highlight salient points across all ophthalmology subspecialties. Features detailed updates on key evolving topics such as the spectrum of macular disease, with many new disorders added to this edition across a range of subspecialties. Increased emphasis on practical investigation and management. Includes 2,600 illustrations, images and artworks, with over 900 brand new for this edition, including ultra wide-field imaging, fundus autofluorescence, and high-resolution OCT. Consult this title on your favourite e-reader.

Author : Rosario Caltabiano,Carla Loreto
Publisher : MDPI
Page : 168 pages
File Size : 46,7 Mb
Release : 2021-09-02
Category : Medical
ISBN : 9783036504001

Get Book

Immunohistochemical Expression by Rosario Caltabiano,Carla Loreto Pdf

Immunohistochemistry (IHC) is an ancillary method, widely used in pathologists’ practice, that allows identifying diagnostic and prognostic/predictive of therapeutic response protein markers on tissue samples by the use of specific monoclonal antibodies and chromogenic substances that guarantee the visualization of an antibody–antigene binding complex under a light microscope [1]. Coon et al., in 1941 [2], first introduced the use of fluorochrome-conjugated antibodies in clinical practice. Since then, IHC has gone from being a useful tool for identifying the differentiation line of otherwise undifferentiated cells to a technique capable of providing not only diagnostic but also prognostic and predictive indications of responses to specific therapeutic options [1,3]. The abovementioned peculiarities have made IHC one of the most used ancillary methods in the histopathological approach to human neoplastic and non-neoplastic diseases [3-5]. This Special Issue contains 11 accepted papers that provide readers with a comprehensive update on current and future applications of IHC in medical practice.

Author : Sonal S. Chaugule,Santosh G. Honavar,Paul T. Finger
Publisher : Springer Nature
Page : 213 pages
File Size : 52,7 Mb
Release : 2019-10-03
Category : Medical
ISBN : 9783030187576

Get Book

Surgical Ophthalmic Oncology by Sonal S. Chaugule,Santosh G. Honavar,Paul T. Finger Pdf

Designed as an easy-to-use, practical guide to tumors of the eye, lids, and orbit, this Open Access book comprehensively addresses surgical treatment and management of diseases related to ophthalmic oncology. Surgical Ophthalmic Oncology: A Collaborative Open Access Reference is an ideal reference for general ophthalmologists, surgeons, fellows and trainees around the world who encounter these diseases in the care of their patients. Notably, this book includes considerations for those ophthalmologists offering subspecialty care in environments with limited access to advanced technology and instrumentation. Individual chapters address diagnostic indications, pre-operative and post-operative concerns, and provide detailed explanations of surgical techniques required to manage various eye cancer ailments with help of ample illustrations. High-quality videos included throughout the book provide readers with the opportunity to review surgical steps in real-time as a learning tool. Chapters thoroughly cover tumors of eyelid, cornea and conjunctiva, orbit as well as intraocular tumors, while later chapters discuss ophthalmic radiation therapy. The book concludes with a section on ophthalmic pathology which details essential guidelines on relevant aspects from specimen collection and transport, to interpretation of the pathology report. Surgical Ophthalmic Oncology: A Collaborative Open Access Reference is a unique and necessary valuable resource for ophthalmologists, trainees, and related medical professionals working in underserved areas in providing quality care for patients suffering from ocular cancers.

Author : Bertil Damato,Arun D. Singh
Publisher : Springer
Page : 382 pages
File Size : 44,6 Mb
Release : 2014-05-20
Category : Medical
ISBN : 9783642542558

Get Book

Clinical Ophthalmic Oncology by Bertil Damato,Arun D. Singh Pdf

Written by internationally renowned experts, Clinical Ophthalmic Oncology provides practical guidance and advice on the diagnosis and management of the complete range of ocular cancers. The book supplies all of the state-of-the-art knowledge required in order to identify these cancers early and to treat them as effectively as possible. Using the information provided, readers will be able to provide effective patient care using the latest knowledge on all aspects of ophthalmic oncology, to verify diagnostic conclusions based on comparison with numerous full-color clinical photographs, and to locate required information quickly owing to the clinically focused and user-friendly format. This volume, devoted solely to uveal tumors, explains the various diagnostic and biopsy techniques that may be used and describes the therapeutic options of potential value for different types of tumor.

Author : Alfredo Conti,Pantaleo Romanelli,Evangelos Pantelis,Scott G. Soltys,Young Hyun Cho,Michael Lim
Publisher : Springer Nature
Page : 588 pages
File Size : 55,5 Mb
Release : 2020-08-07
Category : Medical
ISBN : 9783030506681

Get Book

CyberKnife NeuroRadiosurgery by Alfredo Conti,Pantaleo Romanelli,Evangelos Pantelis,Scott G. Soltys,Young Hyun Cho,Michael Lim Pdf

This book is a practical guide on image-guided robotic (CyberKnife®) radiosurgery of the brain and the spine. The volume introduces the radiosurgical community to the potential of image-guidance in the treatment of neurosurgical diseases including neuro-oncological, vascular and functional disorders. Principles of image-guided radiosurgery, including physics and radiobiology are considered. Each chapter provides a critical review of the literature and analyses of several aspects to offer an assessment of single and hypofractionated treatments. Based on the authors’ experience, tables or summaries presenting the treatment approaches and associated risks are included as well. Providing a practical guide to define the selection of dose, fractionation schemes, isodose line, margins, imaging, constraints to the structures at risk will support safe practice of neuroradiosurgery. This book aims to shed new light on the treatment of neoplastic and non-neoplastic diseases of the central nervous system using the CyberKnife® image-guided robotic radiosurgery system. It will be adopted by neurosurgery residents and neurosurgery consultants as well as residents in radiation oncology and radiation oncologists; medical physicists involved in radiosurgery procedures may also benefit from this book.

Author : Ilkka Raivio
Publisher : Unknown
Page : 64 pages
File Size : 42,5 Mb
Release : 1977
Category : Cancer
ISBN : 8787473186

Get Book

Uveal Melanoma in Finland by Ilkka Raivio Pdf