Vaccine Analysis Strategies Principles And Control

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Vaccine Analysis: Strategies, Principles, and Control

Brian K. Nunnally,Vincent E. Turula,Robert D. Sitrin

Author : Brian K. Nunnally,Vincent E. Turula,Robert D. Sitrin
Publisher : Springer
Page : 669 pages
File Size : 40,7 Mb
Release : 2014-11-27
Category : Medical
ISBN : 9783662450246

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Vaccine Analysis: Strategies, Principles, and Control by Brian K. Nunnally,Vincent E. Turula,Robert D. Sitrin Pdf

This book is an indispensable tool for anyone involved in the research, development, or manufacture of new or existing vaccines. It describes a wide array of analytical and quality control technologies for the diverse vaccine modalities. Topics covered include the application of both classical and modern bio-analytical tools; procedures to assure safety and control of cross contamination; consistent biological transition of vaccines from the research laboratory to manufacturing scale; whole infectious attenuated organisms, such as live-attenuated and inactivated whole-cell bacterial vaccines and antiviral vaccines using attenuated or inactivated viruses; principles of viral inactivation and the application of these principles to vaccine development; recombinant DNA approaches to produce modern prophylactic vaccines; bacterial subunit, polysaccharide and glycoconjugate vaccines; combination vaccines that contain multiple antigens as well as regulatory requirements and the hurdles of licensure.

Framework for Equitable Allocation of COVID-19 Vaccine

National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice,Board on Health Sciences Policy,Committee on Equitable Allocation of Vaccine for the Novel Coronavirus

Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice,Board on Health Sciences Policy,Committee on Equitable Allocation of Vaccine for the Novel Coronavirus
Publisher : National Academies Press
Page : 273 pages
File Size : 43,6 Mb
Release : 2020-11-30
Category : Medical
ISBN : 9780309682244

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Framework for Equitable Allocation of COVID-19 Vaccine by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice,Board on Health Sciences Policy,Committee on Equitable Allocation of Vaccine for the Novel Coronavirus Pdf

In response to the coronavirus disease 2019 (COVID-19) pandemic and the societal disruption it has brought, national governments and the international community have invested billions of dollars and immense amounts of human resources to develop a safe and effective vaccine in an unprecedented time frame. Vaccination against this novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), offers the possibility of significantly reducing severe morbidity and mortality and transmission when deployed alongside other public health strategies and improved therapies. Health equity is intertwined with the impact of COVID-19 and there are certain populations that are at increased risk of severe illness or death from COVID-19. In the United States and worldwide, the pandemic is having a disproportionate impact on people who are already disadvantaged by virtue of their race and ethnicity, age, health status, residence, occupation, socioeconomic condition, or other contributing factors. Framework for Equitable Allocation of COVID-19 Vaccine offers an overarching framework for vaccine allocation to assist policy makers in the domestic and global health communities. Built on widely accepted foundational principles and recognizing the distinctive characteristics of COVID-19, this report's recommendations address the commitments needed to implement equitable allocation policies for COVID-19 vaccine.

The Ethics of Vaccination

Alberto Giubilini

Author : Alberto Giubilini
Publisher : Springer
Page : 126 pages
File Size : 40,9 Mb
Release : 2018-12-28
Category : Philosophy
ISBN : 9783030020682

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The Ethics of Vaccination by Alberto Giubilini Pdf

This open access book discusses individual, collective, and institutional responsibilities with regard to vaccination from the perspective of philosophy and public health ethics. It addresses the issue of what it means for a collective to be morally responsible for the realisation of herd immunity and what the implications of collective responsibility are for individual and institutional responsibilities. The first chapter introduces some key concepts in the vaccination debate, such as ‘herd immunity’, ‘public goods’, and ‘vaccine refusal’; and explains why failure to vaccinate raises certain ethical issues. The second chapter analyses, from a philosophical perspective, the relationship between individual, collective, and institutional responsibilities with regard to the realisation of herd immunity. The third chapter is about the principle of least restrictive alternative in public health ethics and its implications for vaccination policies. Finally, the fourth chapter presents an ethical argument for unqualified compulsory vaccination, i.e. for compulsory vaccination that does not allow for any conscientious objection. The book will appeal to philosophers interested in public health ethics and the general public interested in the philosophical underpinning of different arguments about our moral obligations with regard to vaccination.

Vaccines for the 21st Century

Institute of Medicine,Division of Health Promotion and Disease Prevention,Committee to Study Priorities for Vaccine Development

Author : Institute of Medicine,Division of Health Promotion and Disease Prevention,Committee to Study Priorities for Vaccine Development
Publisher : National Academies Press
Page : 472 pages
File Size : 51,5 Mb
Release : 2001-02-21
Category : Medical
ISBN : 9780309174985

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Vaccines for the 21st Century by Institute of Medicine,Division of Health Promotion and Disease Prevention,Committee to Study Priorities for Vaccine Development Pdf

Vaccines have made it possible to eradicate the scourge of smallpox, promise the same for polio, and have profoundly reduced the threat posed by other diseases such as whooping cough, measles, and meningitis. What is next? There are many pathogens, autoimmune diseases, and cancers that may be promising targets for vaccine research and development. This volume provides an analytic framework and quantitative model for evaluating disease conditions that can be applied by those setting priorities for vaccine development over the coming decades. The committee describes an approach for comparing potential new vaccines based on their impact on morbidity and mortality and on the costs of both health care and vaccine development. The book examines: Lessons to be learned from the polio experience. Scientific advances that set the stage for new vaccines. Factors that affect how vaccines are used in the population. Value judgments and ethical questions raised by comparison of health needs and benefits. The committee provides a way to compare different forms of illness and set vaccine priorities without assigning a monetary value to lives. Their recommendations will be important to anyone involved in science policy and public health planning: policymakers, regulators, health care providers, vaccine manufacturers, and researchers.

The Children's Vaccine Initiative

Institute of Medicine,Committee on the Children's Vaccine Initiative: Planning Alternative Strategies

Author : Institute of Medicine,Committee on the Children's Vaccine Initiative: Planning Alternative Strategies
Publisher : National Academies Press
Page : 238 pages
File Size : 47,9 Mb
Release : 1993-02-01
Category : Medical
ISBN : 9780309049405

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The Children's Vaccine Initiative by Institute of Medicine,Committee on the Children's Vaccine Initiative: Planning Alternative Strategies Pdf

The Children's Vaccine Initiative is an international endeavor to ensure that children throughout the world are immunized. This book notes that one of the best opportunities to address the growing problem of immunization in the United States and to improve the health of children in developing countries lies in marshaling the vaccine development and production efforts in the United States and abroad. The book contains information on the nature and status of vaccine development and production efforts in the United States and abroad, and it recommends ways to enhance participation in the International Children's Vaccine Initiative.

Priorities for the National Vaccine Plan

Institute of Medicine,Board on Population Health and Public Health Practice,Committee on Review of Priorities in the National Vaccine Plan

Author : Institute of Medicine,Board on Population Health and Public Health Practice,Committee on Review of Priorities in the National Vaccine Plan
Publisher : National Academies Press
Page : 368 pages
File Size : 42,8 Mb
Release : 2010-05-17
Category : Medical
ISBN : 9780309156202

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Priorities for the National Vaccine Plan by Institute of Medicine,Board on Population Health and Public Health Practice,Committee on Review of Priorities in the National Vaccine Plan Pdf

Vaccination is a fundamental component of preventive medicine and public health. The use of vaccines to prevent infectious diseases has resulted in dramatic decreases in disease, disability, and death in the United States and around the world. The current political, economic, and social environment presents both opportunities for and challenges to strengthening the U.S. system for developing, manufacturing, regulating, distributing, funding, and administering safe and effective vaccines for all people. Priorities for the National Vaccine Plan examines the extraordinarily complex vaccine enterprise, from research and development of new vaccines to financing and reimbursement of immunization services. Priorities for the National Vaccine Plan examines the extraordinarily complex vaccine enterprise, from research and development of new vaccines to financing and reimbursement of immunization services. The book makes recommendations about priority actions in the update to the National Vaccine Plan that are intended to achieve the objectives of disease prevention and enhancement of vaccine safety. It is centered on the plan's five goals in the areas of vaccine development, safety, communication, supply and use, and global health.

Immunization in Practice

World Health Organization

Author : World Health Organization
Publisher : World Health Organization
Page : 292 pages
File Size : 46,7 Mb
Release : 2015
Category : Medical
ISBN : 9789241549097

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Immunization in Practice by World Health Organization Pdf

This practical guide contains seven modules targeted at district and health facility staff. It intends to meet the demands to improve immunization services so as to reach more infants in a sustainable way, building upon the experiences of polio eradication. It includes materials adapted from polio on planning, monitoring and use of data to improve the service, that can be used at any level. Revising the manual has been a team exercise. There are contributions from a large number of experts, organizations and institutions. This new edition has seven modules. Several new vaccines that have become more readily available and used in recent years have been added. Also the section on integration with other health interventions has been expanded as exciting opportunities and experiences have become evident in the years following the previous edition. Module 1: Target diseases and vaccines Module 2: The vaccine cold chain Module 3: Ensuring safe injections Module 4: Microplanning for reaching every community Module 5: Managing an immunization session Module 6: Monitoring and surveillance Module 7: Partnering with communities.

Immunization Safety Review

Institute of Medicine,Board on Health Promotion and Disease Prevention,Immunization Safety Review Committee

Author : Institute of Medicine,Board on Health Promotion and Disease Prevention,Immunization Safety Review Committee
Publisher : National Academies Press
Page : 152 pages
File Size : 53,7 Mb
Release : 2002-07-02
Category : Medical
ISBN : 9780309169882

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Immunization Safety Review by Institute of Medicine,Board on Health Promotion and Disease Prevention,Immunization Safety Review Committee Pdf

By two years of age, healthy infants in the United States can receive up to 20 vaccinations to protect against 11 diseases. Although most people know that vaccines effectively protect against serious infectious diseases, approximately one-quarter of parents in a recent survey believe that infants get more vaccines than are good for them, and that too many immunizations could overwhelm an infant's immune system. The Immunization Safety Review Committee reviewed the evidence regarding the hypothesis that multiple immunizations increase the risk for immune dysfunction. Specifically, the committee looked at evidence of potential biological mechanisms and at epidemiological evidence for or against causality related to risk for infections, the autoimmune disease type 1 diabetes, and allergic disorders.

Veterinary Vaccines

Samia Metwally,Gerrit Viljoen,Ahmed El Idrissi

Author : Samia Metwally,Gerrit Viljoen,Ahmed El Idrissi
Publisher : John Wiley & Sons
Page : 350 pages
File Size : 46,9 Mb
Release : 2021-04-01
Category : Medical
ISBN : 9781119506263

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Veterinary Vaccines by Samia Metwally,Gerrit Viljoen,Ahmed El Idrissi Pdf

Provides a concise and authoritative reference on the use of vaccines against diseases of livestock Compiled by Senior Animal Health Officers at The Food and Agriculture Organization of the United Nations, and with contributions from international leading experts, Veterinary Vaccines: Principles and Applications is a concise and authoritative reference featuring easily readable reviews of the latest research in vaccinology and vaccine immune response to pathogens of major economic impact to livestock. It covers advice and recommendations for vaccine production, quality control, and effective vaccination schemes including vaccine selection, specifications, vaccination programs, vaccine handling in the field, application, failures, and assessment of herd protection. In addition, the book presents discussions on the current status and potential future developments of vaccines and vaccination against selected transboundary animal diseases. Provides a clear and comprehensive guide on using veterinary vaccines to protect livestock from diseases Teaches the principles of vaccinology and vaccine immune response Highlights the vaccine production schemes and standards for quality control testing Offers easy-to-read reviews of the most current research on the subject Gives readers advice and recommendations on which vaccination schemes are most effective Discusses the today’s state of vaccines and vaccination against selected transboundary animal diseases as well as possible future developments in the field Veterinary Vaccines: Principles and Applications is an important resource for veterinary practitioners, animal health department officials, vaccine scientists, and veterinary students. It will also be of interest to professional associations and NGO active in livestock industry.

Immunization Safety Review

Institute of Medicine,Board on Health Promotion and Disease Prevention,Immunization Safety Review Committee

Author : Institute of Medicine,Board on Health Promotion and Disease Prevention,Immunization Safety Review Committee
Publisher : National Academies Press
Page : 118 pages
File Size : 41,9 Mb
Release : 2003-12-26
Category : Medical
ISBN : 9780309086103

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Immunization Safety Review by Institute of Medicine,Board on Health Promotion and Disease Prevention,Immunization Safety Review Committee Pdf

The Immunization Safety Review Committee was established by the Institute of Medicine (IOM) to evaluate the evidence on possible causal associations between immunizations and certain adverse outcomes, and to then present conclusions and recommendations. The committee's mandate also includes assessing the broader societal significance of these immunization safety issues. While all the committee members share the view that immunization is generally beneficial, none of them has a vested interest in the specific immunization safety issues that come before the group. The committee reviews three immunization safety review topics each year, addressing each one at a time. In this fifth report in a series, the committee examines the hypothesis that exposure to polio vaccine contaminated with simian virus 40 (SV40), a virus that causes inapparent infection in some monkeys, can cause certain types of cancer.

Bioprocessing of Viral Vaccines

Amine Kamen,Laura Cervera

Author : Amine Kamen,Laura Cervera
Publisher : CRC Press
Page : 329 pages
File Size : 51,5 Mb
Release : 2022-09-06
Category : Medical
ISBN : 9781000643022

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Bioprocessing of Viral Vaccines by Amine Kamen,Laura Cervera Pdf

This book focuses on cell culture-produced viral vaccines to meet the needs of the rapidly expanding research and development in academia and industry in the field. This book introduces the basic principles of vaccination and the manufacturing of viral vaccines. Bioprocessing of Viral Vaccines, will provide an overview of the advanced strategies needed to respond to the challenges of new and established viral infection diseases. The first few chapters cover the basics of virology and immunology as essential concepts to understand the function and design of viral vaccines. The core of the content is dedicated to process development, including upstream processing and cell culture of viral vaccines, downstream processing, and extensive analytical technologies specific to viral vaccines. Advanced process analytical technologies (PAT) and Quality by Design (QbD) concepts are also introduced in the context of vaccine manufacturing. The case studies included cover inactivated, attenuated vaccines exemplified by influenza vaccines, sub-unit vaccines exemplified by Virus Like Particles (VLPs: HPV vaccines) and sub-unit vaccines (Flublock), vectored vaccines: adenoviruses and Vesicular stomatitis Virus (VSV) vectored vaccines, genomic vaccines (DNA and mRNA) vaccines as developed for COVID-19 response in particular and a review of COVID-19 vaccines approved or in advanced clinical trials. This book is aimed at graduate engineers and professionals in the fields of vaccinology, bioprocessing, and biomanufacturing of viral vaccines.

Guidance for Managing Ethical Issues in Infectious Disease Outbreaks

World Health Organization

Author : World Health Organization
Publisher : Unknown
Page : 0 pages
File Size : 44,7 Mb
Release : 2016
Category : Medical
ISBN : 9241549831

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Guidance for Managing Ethical Issues in Infectious Disease Outbreaks by World Health Organization Pdf

"Infectious disease outbreaks are frequently characterized by scientific uncertainty, social and institutional disruption, and an overall climate of fear and distrust. Policy makers and public health professionals may be forced to weigh and prioritize potentially competing ethical values in the face of severe time and resource constraints. This document seeks to assist policy-makers, health care providers, researchers, and others prepare for outbreak situations by anticipating and preparing for the critical ethical issues likely to arise."--Publisher.

Crisis Communication Related to Vaccine Safety

W. H. O. Regional WHO Regional Office for Europe,Centers for Centers for Disease Control

Author : W. H. O. Regional WHO Regional Office for Europe,Centers for Centers for Disease Control
Publisher : Pan American Health Organization
Page : 76 pages
File Size : 52,7 Mb
Release : 2021-02-03
Category : Electronic
ISBN : 9275123136

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Crisis Communication Related to Vaccine Safety by W. H. O. Regional WHO Regional Office for Europe,Centers for Centers for Disease Control Pdf

Vaccine- and vaccination-related crises require a communication response that is different from the communication strategies used to promote the benefits and importance of vaccines in general. This document presents the technical guidance needed to develop a communication plan that is appropriate for managing crises related to vaccine safety. This guidance will be useful for managers in the areas of immunization and vaccine and vaccination safety. They will also help preparedness and response teams working in safety crises to optimize their communication plans in order to regain, maintain, or strengthen trust in vaccines, vaccination, and immunization programs in general. Each chapter presents a phase (preparation, implementation, and evaluation) with suggested actions and support tools to prepare, implement, and evaluate a communication response in a crisis situation. Also, some sections can also be used to strengthen routine national communication activities such as interaction with media, message generation, spokespeople preparation among others. The current document complements the Manual for the surveillance of events supposedly attributable to vaccination or immunization (ESAVI) in the Region of the Americas. This document is published within the framework of a joint project that aims to promote communication-related to safe vaccination in the Region of the Americas and support health authorities that need to develop a communication plan to manage crises related to vaccine safety. Some of the sections in this publication are based on the guidance documents available in the WHO Regional Office for Europe's virtual library and can be consulted on their website.

Mass Vaccination: Global Aspects - Progress and Obstacles

Stanley A. Plotkin

Author : Stanley A. Plotkin
Publisher : Springer Science & Business Media
Page : 276 pages
File Size : 55,5 Mb
Release : 2006-09-21
Category : Medical
ISBN : 9783540365839

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Mass Vaccination: Global Aspects - Progress and Obstacles by Stanley A. Plotkin Pdf

Mass immunization is the blitzkrieg of vaccination practice. It serves to rapidly protect populations, both because of the high coverage achieved and because of the herd immunity thereby induced. However, as in war, mass immunization campaigns must be conducted intelligently, with careful strategy and strong attention to logistics of supply and deployment. If conducted badly, mass immunization may fail or even be counter-productive. In this volume, some of the most successful practitioners of mass im- nization tell us about its art and science. David Heymann and Bruce Aylward of WHO begin the book with a theoretical and practical overview of mass immunization. Michael Lane, who participated in the successful effort to eradicate smallpox relates how this was done using mass vaccination and other strategies. Application of mass immunization by the US military is c- ered by John Grabenstein and Remington Nevin, who have a large experience in these matters. Karen Noakes and David Salisbury recount the striking s- cesses of mass immunization in the United Kingdom. The global control of the clostridia that produce diphtheria toxin is described by Charles Vitek. Hepa- tis A is decreasing dramatically under the impact of large-scale vaccination, as Francis André illustrates. The French experience with Hepatitis B vac- nation has been mixed, and François Denis and Daniel Levy-Bruhl explain the circumstances. In?uenza vaccination is an annual example of large-scale campaigns, the complexity of which is recounted by Benjamin Schwartz and Pascale Wortley.

Epidemiology and Prevention of Vaccine-Preventable Diseases, 13th Edition E-Book

Jennifer Hamborsky, MPH, MCHES,Andrew Kroger, MD, MPH,Charles (Skip) Wolfe

Author : Jennifer Hamborsky, MPH, MCHES,Andrew Kroger, MD, MPH,Charles (Skip) Wolfe
Publisher : Public Health Foundation
Page : 512 pages
File Size : 43,5 Mb
Release : 2015-10-19
Category : Health & Fitness
ISBN : 9780990449126

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Epidemiology and Prevention of Vaccine-Preventable Diseases, 13th Edition E-Book by Jennifer Hamborsky, MPH, MCHES,Andrew Kroger, MD, MPH,Charles (Skip) Wolfe Pdf

The Public Health Foundation (PHF) in partnership with the Centers for Disease Control and Prevention (CDC) is pleased to announce the availability of Epidemiology and Prevention of Vaccine-Preventable Diseases, 13th Edition or “The Pink Book” E-Book. This resource provides the most current, comprehensive, and credible information on vaccine-preventable diseases, and contains updated content on immunization and vaccine information for public health practitioners, healthcare providers, health educators, pharmacists, nurses, and others involved in administering vaccines. “The Pink Book E-Book” allows you, your staff, and others to have quick access to features such as keyword search and chapter links. Online schedules and sources can also be accessed directly through e-readers with internet access. Current, credible, and comprehensive, “The Pink Book E-Book” contains information on each vaccine-preventable disease and delivers immunization providers with the latest information on: Principles of vaccination General recommendations on immunization Vaccine safety Child/adult immunization schedules International vaccines/Foreign language terms Vaccination data and statistics The E-Book format contains all of the information and updates that are in the print version, including: · New vaccine administration chapter · New recommendations regarding selection of storage units and temperature monitoring tools · New recommendations for vaccine transport · Updated information on available influenza vaccine products · Use of Tdap in pregnancy · Use of Tdap in persons 65 years of age or older · Use of PCV13 and PPSV23 in adults with immunocompromising conditions · New licensure information for varicella-zoster immune globulin Contact [email protected] for more information. For more news and specials on immunization and vaccines visit the Pink Book's Facebook fan page

Vaccine Analysis Strategies Principles And Control

Vaccine Analysis: Strategies, Principles, and Control by Brian K. Nunnally,Vincent E. Turula,Robert D. Sitrin Pdf

The Ethics of Vaccination by Alberto Giubilini Pdf

Vaccines for the 21st Century by Institute of Medicine,Division of Health Promotion and Disease Prevention,Committee to Study Priorities for Vaccine Development Pdf

The Children's Vaccine Initiative by Institute of Medicine,Committee on the Children's Vaccine Initiative: Planning Alternative Strategies Pdf

Priorities for the National Vaccine Plan by Institute of Medicine,Board on Population Health and Public Health Practice,Committee on Review of Priorities in the National Vaccine Plan Pdf

Immunization in Practice by World Health Organization Pdf

Immunization Safety Review by Institute of Medicine,Board on Health Promotion and Disease Prevention,Immunization Safety Review Committee Pdf

Veterinary Vaccines by Samia Metwally,Gerrit Viljoen,Ahmed El Idrissi Pdf

Immunization Safety Review by Institute of Medicine,Board on Health Promotion and Disease Prevention,Immunization Safety Review Committee Pdf

Bioprocessing of Viral Vaccines by Amine Kamen,Laura Cervera Pdf

Guidance for Managing Ethical Issues in Infectious Disease Outbreaks by World Health Organization Pdf

Crisis Communication Related to Vaccine Safety by W. H. O. Regional WHO Regional Office for Europe,Centers for Centers for Disease Control Pdf

Mass Vaccination: Global Aspects - Progress and Obstacles by Stanley A. Plotkin Pdf

Epidemiology and Prevention of Vaccine-Preventable Diseases, 13th Edition E-Book by Jennifer Hamborsky, MPH, MCHES,Andrew Kroger, MD, MPH,Charles (Skip) Wolfe Pdf

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