Vicinal Diaryl Substituted Heterocycles

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Vicinal Diaryl Substituted Heterocycles

M. R. Yadav,P. R. Murumkar,R. B. Ghuge
Vicinal Diaryl Substituted Heterocycles Book PDF

Author : M. R. Yadav,P. R. Murumkar,R. B. Ghuge
Publisher : Elsevier
Page : 430 pages
File Size : 52,8 Mb
Release : 2018-03-14
Category : Science
ISBN : 9780081022498

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Vicinal Diaryl Substituted Heterocycles by M. R. Yadav,P. R. Murumkar,R. B. Ghuge Pdf

Vicinal Diaryl-Substituted Heterocycles: A Gold Mine for the Discovery of Novel Therapeutic Agents draws together all of the key information about these compounds in one place for the first time. Following an informative overview of the importance of these structures to the discovery of potential therapeutic agents, the text goes on to outline the main compound types, with each chapter focusing on the activities of a different structure. Designed to support researchers by consolidating this important information in a single, practical guide, the authors hope to encourage further advancement and development in the discovery of novel therapeutic agents. As flexible building blocks for the production of novel compounds, vicinal diaryl-substituted heterocycles are a rich source of leads for the development of new drugs. Their adaptability means that they can be used to produce structures with a broad range of attractive characteristics, and a large number of vicinal diaryl-substituted heterocyclic compounds have already been synthesized and investigated by medicinal chemists as promising lead molecules. Collects together details of the key vicinal diaryl-substituted heterocyclic compounds in one place for the first time Highlights biological activities and SAR of derivatives Structured practically for ease of navigation between different derivatives

Advances in Heterocyclic Chemistry

Anonim
Advances in Heterocyclic Chemistry Book PDF

Author : Anonim
Publisher : Academic Press
Page : 492 pages
File Size : 45,6 Mb
Release : 2020-05-08
Category : Science
ISBN : 9780128211687

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Advances in Heterocyclic Chemistry by Anonim Pdf

Advances in Heterocyclic Chemistry is the definitive series in the field - one of great importance to organic chemists, polymer chemists, and many biological scientists. Because biology and organic chemistry increasingly intersect, the associated nomenclature also is being used more frequently in explanations. Written by established authorities in the field from around the world, this comprehensive review combines descriptive synthetic chemistry and mechanistic insight to yield an understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds. Considered the definitive serial in the field of heterocyclic chemistry Serves as the go-to reference for organic chemists, polymer chemists and many biological scientists Provides the latest comprehensive reviews written by established authorities in the field Combines descriptive synthetic chemistry and mechanistic insight to enhance understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds

Artificial Metalloenzymes and MetalloDNAzymes in Catalysis

Montserrat Diéguez,Jan-E. Bäckvall,Oscar Pàmies
Artificial Metalloenzymes and MetalloDNAzymes in Catalysis Book PDF

Author : Montserrat Diéguez,Jan-E. Bäckvall,Oscar Pàmies
Publisher : John Wiley & Sons
Page : 1200 pages
File Size : 52,6 Mb
Release : 2018-02-21
Category : Technology & Engineering
ISBN : 9783527804078

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Artificial Metalloenzymes and MetalloDNAzymes in Catalysis by Montserrat Diéguez,Jan-E. Bäckvall,Oscar Pàmies Pdf

An important reference for researchers in the field of metal-enzyme hybrid catalysis Artificial Metalloenzymes and MetalloDNAzymes in Catalysis offers a comprehensive review of the most current strategies, developed over recent decades, for the design, synthesis, and optimization of these hybrid catalysts as well as material about their application. The contributors—noted experts in the field—present information on the preparation, characterization, and optimization of artificial metalloenzymes in a timely and authoritative manner. The authors present a thorough examination of this interesting new platform for catalysis that combines the excellent selective recognition/binding properties of enzymes with transition metal catalysts. The text includes information on the various applications of metal-enzyme hybrid catalysts for novel reactions, offers insights into the latest advances in the field, and contains an informative perspective on the future: Explores the development of artificial metalloenzymes, the modern and strongly evolving research field on the verge of industrial application Contains a comprehensive reference to the research area of metal-enzyme hybrid catalysis that has experienced tremendous growth in recent years Includes contributions from leading researchers in the field Shows how this new catalysis combines the selective recognition/binding properties of enzymes with transition metal catalysts Written for catalytic chemists, bioinorganic chemists, biochemists, and organic chemists, Artificial Metalloenzymes and MetalloDNAzymes in Catalysis offers a unique reference to the fundamentals, concepts, applications, and the most recent developments for more efficient and sustainable synthesis.

Modern Strategies for Heterocycle Synthesis

Gianfranco Favi
Modern Strategies for Heterocycle Synthesis Book PDF

Author : Gianfranco Favi
Publisher : MDPI
Page : 372 pages
File Size : 51,6 Mb
Release : 2021-03-17
Category : Medical
ISBN : 9783036503400

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Modern Strategies for Heterocycle Synthesis by Gianfranco Favi Pdf

Heterocycles feature widely in natural products, agrochemicals, pharmaceuticals and dyes, and their synthesis is of great interest to synthetic chemists in both academia and industry. The contributions of recent applications of new methodologies in C–H activation, photoredox chemistry, cross-coupling strategies, borrowing hydrogen catalysis, multicomponent and solvent-free reactions, regio- and stereoselective syntheses, as well as other new, attractive approaches for the construction of heterocyclic scaffolds are of great interest. This Special Issue is dedicated to featuring the latest research that is ongoing in the field of heterocyclic synthesis. It is expected that most submissions will focus on five- and six-membered oxygen and nitrogen-containing heterocycles, but structures incorporating other rings/heteroatoms will also be considered. Original research (communications, full papers and reviews) that discusses innovative methodologies for assembling heterocycles with potential application in materials, catalysis and medicine are therefore welcome.

Bioactive Heterocycles VI

Noboru Motohashi
Bioactive Heterocycles VI Book PDF

Author : Noboru Motohashi
Publisher : Springer
Page : 283 pages
File Size : 51,6 Mb
Release : 2008-07-02
Category : Science
ISBN : 9783540792185

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Bioactive Heterocycles VI by Noboru Motohashi Pdf

Heterocyclic chemistry is the biggest branch of chemistry covering two-thirds of the chemical literature and this book covers the hot topics of frontier research summarized by reputed scientists in the field.

Heterocycles via Cross Dehydrogenative Coupling

Ananya Srivastava,Chandan K. Jana
Heterocycles via Cross Dehydrogenative Coupling Book PDF

Author : Ananya Srivastava,Chandan K. Jana
Publisher : Springer Nature
Page : 494 pages
File Size : 54,8 Mb
Release : 2019-08-23
Category : Science
ISBN : 9789811391446

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Heterocycles via Cross Dehydrogenative Coupling by Ananya Srivastava,Chandan K. Jana Pdf

This book discusses the developments in the synthesis and functionalization of different heterocycles based on the formation of carbon-carbon (C-C) and carbon-heteroatom (C-X) bonds using cross-dehydrogenative coupling (CDC). Consisting of 13 chapters, the book systematically describes the advances in the synthesis and functionalization of nitrogen, oxygen, and sulfur-containing heterocycles. It also discusses the various mechanistic pathways to help readers gain an in-depth understanding of the CDC reactions of heterocycles. Lastly, in order to promote green chemistry, it addresses a range of metal-free CDC reactions of heterocycles – an area that has attracted significant attention in both academic and industrial research.

Advances in Heterocyclic Chemistry

Alan R. Katritzky
Advances in Heterocyclic Chemistry Book PDF

Author : Alan R. Katritzky
Publisher : Academic Press
Page : 312 pages
File Size : 49,7 Mb
Release : 2011-02-17
Category : Science
ISBN : 9780123854650

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Advances in Heterocyclic Chemistry by Alan R. Katritzky Pdf

Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area—one of great importance to organic chemists, polymer chemists, and many biological scientists. Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties. Provides up-to-date material on a fast-growing and highly topical subject area Contains the latest research covering a wide variety of heterocyclic topics Written by leading authorities and designed as a handbook for students and industry and academic researchers

Bio-Based Solvents

François Jérôme,Rafael Luque
Bio Based Solvents Book PDF

Author : François Jérôme,Rafael Luque
Publisher : John Wiley & Sons
Page : 200 pages
File Size : 51,9 Mb
Release : 2017-06-29
Category : Science
ISBN : 9781119065449

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Bio-Based Solvents by François Jérôme,Rafael Luque Pdf

A multidisciplinary overview of bio-derived solvent applications, life cycle analysis, and strategies required for industrial commercialization This book provides the first and only comprehensive review of the state-of-the-science in bio-derived solvents. Drawing on their own pioneering work in the field, as well as an exhaustive survey of the world literature on the subject, the authors cover all the bases—from bio-derived solvent applications to life cycle analysis to strategies for industrial commercialization—for researchers and professional chemists working across a range of industries. In the increasingly critical area of sustainable chemistry, the search for new and better green solvents has become a top priority. Thanks to their renewability, biodegradability and low toxicity, as well as their potential to promote advantageous organic reactions, green solvents offer the promise of significantly reducing the pernicious effects of chemical processes on human health and the environment. Following an overview of the current solvents markets and the challenges and opportunities presented by bio-derived solvents, a series of dedicated chapters cover all significant classes of solvent arranged by origin and/or chemical structure. Throughout, real-world examples are used to help demonstrate the various advantages, drawbacks, and limitations of each class of solvent. Topics covered include: The commercial potential of various renewably sourced solvents, such as glycerol The various advantages and disadvantages of bio-derived versus petroleum-based solvents Renewably-sourced and waste-derived solvents in the design of eco-efficient processes Life cycle assessment and predictive methods for bio-based solvents Industrial and commercial viability of bio-based solvents now and in the years ahead Potential and limitations of methodologies involving bio-derived solvents New developments and emerging trends in the field and the shape of things to come Considering the vast potential for new and better products suggested by recent developments in this exciting field, Bio-Based Solvents will be a welcome resource among students and researchers in catalysis, organic synthesis, electrochemistry, and pharmaceuticals, as well as industrial chemists involved in manufacturing processes and formulation, and policy makers.

Dienamine Catalysis for Organic Synthesis

Kengadarane Anebouselvy,Dhevalapally B. Ramachary,Indresh Kumar
Dienamine Catalysis for Organic Synthesis Book PDF

Author : Kengadarane Anebouselvy,Dhevalapally B. Ramachary,Indresh Kumar
Publisher : Royal Society of Chemistry
Page : 206 pages
File Size : 52,7 Mb
Release : 2018-03-02
Category : Electronic
ISBN : 9781782620907

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Dienamine Catalysis for Organic Synthesis by Kengadarane Anebouselvy,Dhevalapally B. Ramachary,Indresh Kumar Pdf

In the last decade a new era in asymmetric catalysis has been realised by the discovery of L-proline induced chiral enamines from carbonyls. Inspired by this, researchers have developed many other primary catalytic species in situ, more recently secondary catalytic species such as aminals have been identified for use in asymmetric synthesis. High-yielding asymmetric synthesis of bioactive and natural products through mild catalysis is an efficient approach in reaction engineering. In the early days, synthetic chemists mainly focused on the synthesis of complex molecules, with less attention on the reaction efficiency and eco-friendly conditions. Recent investigations have been directed towards the development of atom economy, eco-friendly and enantioselective synthesis for more targeted and efficient synthesis. Building on the momentum of this rapidly expanding research area, Dienamine catalysis for organic synthesis will provide a comprehensive introduction, from the preformed species, in situ generation and onto their applications in the synthesis of bioactive molecules and natural products.

N-Sulfonated-N-Heterocycles

Galal H. Elgemeie,Rasha A. Azzam,Wafaa A. Zaghary,Ashraf A. Aly,Nadia H Metwally,Mona O. Sarhan,Elshimaa M. Abdelhafez,Rasha E. Elsayed
N Sulfonated N Heterocycles Book PDF

Author : Galal H. Elgemeie,Rasha A. Azzam,Wafaa A. Zaghary,Ashraf A. Aly,Nadia H Metwally,Mona O. Sarhan,Elshimaa M. Abdelhafez,Rasha E. Elsayed
Publisher : Elsevier
Page : 523 pages
File Size : 52,9 Mb
Release : 2022-08-30
Category : Science
ISBN : 9780128221822

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N-Sulfonated-N-Heterocycles by Galal H. Elgemeie,Rasha A. Azzam,Wafaa A. Zaghary,Ashraf A. Aly,Nadia H Metwally,Mona O. Sarhan,Elshimaa M. Abdelhafez,Rasha E. Elsayed Pdf

N-Sulfonated-N-Heterocycles covers the synthesis, chemistry and biological applications of these compounds, focusing on pioneering synthetic approaches, mechanistic insights and their limitations, as well as recent advances in this field. The synthesis of some of N-sulfonated N-heterocycles and their transformation to other useful cyclic and acyclic compounds are discussed, as well as their uses as useful intermediates in the preparation of polymeric and medicinal materials. This book includes detailed methods and protocols, and the focus on applications makes this resource an essential guide for all researchers in the area of organic, medicinal and polymeric synthetic study. Reviews the use of N-sulfonated N-heterocycles as important precursors for the synthesis of biologically active compounds Includes information on synthetically useful transformations of N-sulfonated N-heterocycles Covers a wide synthetic methods used for an important branch of heterocycles and their biological evaluation in detail Features over 500 schemes to illustrate different synthetic pathways and reactions of N-sulfonated N-heterocycles

Heterocyclic Chemistry

John A. Joule,Keith Mills
Heterocyclic Chemistry Book PDF

Author : John A. Joule,Keith Mills
Publisher : John Wiley & Sons
Page : 719 pages
File Size : 55,8 Mb
Release : 2010-06-15
Category : Science
ISBN : 9781405193658

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Heterocyclic Chemistry by John A. Joule,Keith Mills Pdf

This book has so closely matched the requirements of its readership over the years that it has become the first choice for chemists worldwide. Heterocyclic chemistry comprises at least half of all organic chemistry research worldwide. In particular, the vast majority of organic work done in the pharmaceutical and agrochemical industries is heterocyclic chemistry. The fifth edition of Heterocyclic Chemistry maintains the principal objective of earlier editions – to teach the fundamentals of heterocyclic reactivity and synthesis in a way that is understandable to second- and third-year undergraduate chemistry students. The inclusion of more advanced and current material also makes the book a valuable reference text for postgraduate taught courses, postgraduate researchers, and chemists at all levels working with heterocyclic compounds in industry. Fully updated and expanded to reflect important 21st century advances, the fifth edition of this classic text includes the following innovations: Extensive use of colour to highlight changes in structure and bonding during reactions Entirely new chapters on organometallic heterocyclic chemistry, heterocyclic natural products, especially in biochemical processes, and heterocycles in medicine New sections focusing on heterocyclic fluorine compounds, isotopically labeled heterocycles, and solid-phase chemistry, microwave heating and flow reactors in the heterocyclic context Essential teaching material in the early chapters is followed by short chapters throughout the text which capture the essence of heterocyclic reactivity in concise resumés suitable as introductions or summaries, for example for examination preparation. Detailed, systematic discussions cover the reactivity and synthesis of all the important heterocyclic systems. Original references and references to reviews are given throughout the text, vital for postgraduate teaching and for research scientists. Problems, divided into straightforward revision exercises, and more challenging questions (with solutions available online), help the reader to understand and apply the principles of heterocyclic reactivity and synthesis.

Quinoxalines

Vakhid A. Mamedov
Quinoxalines Book PDF

Author : Vakhid A. Mamedov
Publisher : Springer
Page : 437 pages
File Size : 50,6 Mb
Release : 2016-04-26
Category : Science
ISBN : 9783319297736

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Quinoxalines by Vakhid A. Mamedov Pdf

This book reviews the fundamental aspects of quinoxaline chemistry: synthesis, reactions, mechanisms, structure, properties, and uses. The first four chapters present a survey of the developments in quinoxaline chemistry since the publication of the monograph on “Condensed Pyrazines” by Cheeseman and Cookson in 1979. These chapters give comprehensive coverage of all the methods of the synthesis of quinoxalines and the important quinoxaline-containing ring systems such as thiazolo[3,4-a]-, pyrrolo[1,2-a]-, and imidazo[1,5-a]quinoxalines. Chapter five describes many new methods for the construction of quinoxaline macrocycles, which are important in applications such as optical devices and materials. The final chapter reviews all previously known rearrangements of heterocyclic systems that lead to benzimidazole derivatives. Mamedov critically analyses these transformations to reveal a novel acid-catalyzed rearrangement of quinoxalinones giving 2-heteroarylbenzimidazoles and 1-heteroarylbenzimidazolones in the presence of nucleophilic reactants (MAMEDOV Heterocycle Rearrangement). This book is of interest to researchers in the fields of heterocyclic and synthetic organic chemistry.

Green Synthetic Approaches for Biologically Relevant Heterocycles

Goutam Brahmachari
Green Synthetic Approaches for Biologically Relevant Heterocycles Book PDF

Author : Goutam Brahmachari
Publisher : Elsevier
Page : 823 pages
File Size : 50,7 Mb
Release : 2021-02-26
Category : Science
ISBN : 9780323851336

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Green Synthetic Approaches for Biologically Relevant Heterocycles by Goutam Brahmachari Pdf

Green Synthetic Approaches for Biologically Relevant Heterocycles, Second Edition, Volume Two: Green Catalytic Systems and Solvents reviews this significant group of organic compounds within the context of sustainable methods and processes, expanding on the first edition with fully updated coverage and a whole range of new chapters. Volume Two explores green catalytic systems and solvents and the techniques surrounding this approach, including metal and magnetic catalysis to organocatalysis and solid acid catalysis, cycloaddition reactions, and varied approaches using ionic liquids. This updated edition is an essential resource on sustainable approaches for academic researchers, R&D professionals, and students working across medicinal, organic, natural product and green chemistry. Provides fully updated coverage of the field with an emphasis on sustainability Highlights a range of different eco-friendly solvents and environmentally-friendly catalysts Collates the experience of a global team of expert contributors

Green Chemistry: Synthesis of Bioactive Heterocycles

K. L. Ameta,Anshu Dandia
Green Chemistry Synthesis of Bioactive Heterocycles Book PDF

Author : K. L. Ameta,Anshu Dandia
Publisher : Springer
Page : 418 pages
File Size : 43,5 Mb
Release : 2014-06-17
Category : Science
ISBN : 9788132218500

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Green Chemistry: Synthesis of Bioactive Heterocycles by K. L. Ameta,Anshu Dandia Pdf

The book presents a succinct summary of methods for the synthesis and biological activities of various different-sized bioactive heterocycles using different green chemistry synthetic methodologies, like microwave, ultrasonic, water mediated, ionic liquids, etc. The book also provides an insight of how green chemistry techniques are specific to the bioactive heterocyclic compounds.

Chemistry of Biologically Potent Natural Products and Synthetic Compounds

Shahid Ul-Islam,Javid Ahmad Banday
Chemistry of Biologically Potent Natural Products and Synthetic Compounds Book PDF

Author : Shahid Ul-Islam,Javid Ahmad Banday
Publisher : John Wiley & Sons
Page : 434 pages
File Size : 40,8 Mb
Release : 2021-06-29
Category : Science
ISBN : 9781119640349

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Chemistry of Biologically Potent Natural Products and Synthetic Compounds by Shahid Ul-Islam,Javid Ahmad Banday Pdf

In view of their promising biological and pharmaceutical activities, natural product inspired and heterocyclic compounds have recently gained a reputation in the field of medicinal chemistry. Over the past decades, intensive research efforts have been ongoing to understand the synthesis, biochemistry and engineering involved in their preparation and action mechanisms. Several novel natural product derivatives, heterocyclic and other synthetic compounds, have been reported to have shown interesting biological activities including anticancer, antimicrobial, anti-inflammatory, anti-glycemic, anti-allergy and antiviral etc. Chemistry of Biologically Potent Natural Products and Synthetic Compounds provides up-to-date information on new developments and most recent medicinal applications of the natural products and derivatives, as well as the chemistry and synthesis of heterocyclic and other related compounds.