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Author : Abhay P. S. Rathore,Vivian Vasconcelos Costa,Ashley L. St John
Publisher : Frontiers Media SA
Page : 165 pages
File Size : 44,5 Mb
Release : 2022-02-28
Category : Medical
ISBN : 9782889745869
Author : Bernard Gonik
Publisher : Springer Science & Business Media
Page : 285 pages
File Size : 50,7 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461226406
The pregnant host is at risk for any of the viral diseases her nonpregnant counterpart acquires. Additionally, pregnancy heightens our concerns regarding specific viral diseases be cause of their potential for enhanced adverse effects on both maternal and fetal well-being. All too often the obstetrician relinquishes responsibility for the management of the gravida infected by a viral pathogen, and those expert in infectious diseases are confounded by the influence of pregnancy on these conditions. A major goal of this textbook is to narrow the gap between the two aforementioned management dichotomies in the virally infected pregnant woman. Weare at the infancy of our understanding of viral infections in pregnancy. The current and anticipated advancements are due in large part to a burgeoning oftechnological achievements in the areas of immunodiagnostics, molecular biology, and pharmacotherapeutics. Our in utero diagnostic capabilities, both invasive and noninvasive, have also allowed us new opportunities to study the effects of various maternal infectious disease processes on the developing fetus. New insights have been recognized pertaining to the maternal-fetal interface, the placenta, in that this structure is now acknowledged to function as both a mechanical and an immunological barrier to vertical transmission of infection. These observations suggest that there will be an outpouring of new data in the next several years that clinicians will need to master to maintain an appropriate level of expertise in the care of their patients.
Author : Bernard Gonik
Publisher : Springer
Page : 267 pages
File Size : 48,8 Mb
Release : 1994-06-24
Category : Science
ISBN : 0387942076
The pregnant host is at risk for any of the viral diseases her nonpregnant counterpart acquires. Additionally, pregnancy heightens our concerns regarding specific viral diseases be cause of their potential for enhanced adverse effects on both maternal and fetal well-being. All too often the obstetrician relinquishes responsibility for the management of the gravida infected by a viral pathogen, and those expert in infectious diseases are confounded by the influence of pregnancy on these conditions. A major goal of this textbook is to narrow the gap between the two aforementioned management dichotomies in the virally infected pregnant woman. Weare at the infancy of our understanding of viral infections in pregnancy. The current and anticipated advancements are due in large part to a burgeoning oftechnological achievements in the areas of immunodiagnostics, molecular biology, and pharmacotherapeutics. Our in utero diagnostic capabilities, both invasive and noninvasive, have also allowed us new opportunities to study the effects of various maternal infectious disease processes on the developing fetus. New insights have been recognized pertaining to the maternal-fetal interface, the placenta, in that this structure is now acknowledged to function as both a mechanical and an immunological barrier to vertical transmission of infection. These observations suggest that there will be an outpouring of new data in the next several years that clinicians will need to master to maintain an appropriate level of expertise in the care of their patients.
Author : Anthony Carter,Vibeke Dantzer,Thomas Jansson
Publisher : Boydell & Brewer
Page : 456 pages
File Size : 53,7 Mb
Release : 1998
Category : Maternal-fetal exchange
ISBN : 1580460437
The 29 papers contained in this volume look closely at various aspects of what is termed, "The Maternal-Fetal Interface," as it relates to the latest research in placental science. A substantial section of the book is devoted to the troublesome question of vertical transmission of infectious agents: namely, the HIV-1 virus. However, other sections of the volume examine related issues such as drug and toxin transfer across the term placenta and the diversity of placental types and how this can affect a placenta's effectiveness as a barrier. Anthony Carter is at the University of Odense, Denmark Vibeke Dantzer is at the University of Copenhagen, DenmarkThomas Jansson is at the University of Gothenburg, Sweden
Author : Demba Sarr,Ricardo E. Fretes,Ulrike Kemmerling,Sodiomon B. Sirima
Publisher : Frontiers Media SA
Page : 150 pages
File Size : 55,6 Mb
Release : 2020-12-11
Category : Science
ISBN : 9782889662401
Pregnancy is a physiologically and immunologically challenging health state. Immunological and physiological changes throughout the course of pregnancy make pregnant women usually susceptible to infection with microbial agents. Infections with pathogens during pregnancy can have devastating consequences to both the fetus and his/her mother. These infections are linked with adverse pregnancy outcomes. Infections with parasites, viruses, or bacteria can be associated with maternal anemia, abortion, intrauterine growth retardation, preterm delivery, fetal morbidity and high risk of mortality during the first years of life. Despite these significant consequences and complications associated with infections by microbial pathogens during the course of gestation, very little is known about the underlying mechanisms of the pathogenesis and immunopathology of infections during pregnancy. The Research Topic proposed here in, will focus on microbial infections during pregnancy. Studies and review papers addressing the pregnant host/fetus/pathogen interactions, the host/fetus immunological response against infections during gestation, trans-placental transfer of infections during pregnancy are welcome. Topics related to model systems used to mirror the biology in human, the pathogenesis and molecular pathways as well as the mechanisms of the disease at the maternofetal interface including the placenta, the amniotic fluid, and the fetal membranes will be considered making the scope and interest of the topic relatively broad. There is a growing number of pathogens associated with pregnancy. In most cases, women are more susceptible to infections with these pathogens when they become pregnant in comparison to their non-pregnant counterparts. Unfortunately, vertical transmission occurs in most cases but the underlying mechanisms are still unknown. The placenta has always been considered as a barrier against congenital infections but studies have indicated that microbial pathogens breach this barrier. The amniotic fluid, and the fetal membranes are also important components of vertical transmission because of their non-sterile state even in most healthy pregnancies. During pregnancy, infections by malaria or toxoplasmosis as well as other viral or bacterial pathogens lead to an uncontrolled inflammatory response recognized as a significant cause for preterm delivery and intra uterine growth retardation leading to low birth weight, a risk factor to infant morbidity and mortality. To successfully prevent, treat, eradicate or educate about microbial infections during pregnancy, we must understand the molecular mechanisms by which they cause poor birth outcomes including how vertical transmission occurs at the maternofetal interface.
Author : Kristina M. Adams Waldorf,Vikki M. Abrahams
Publisher : Frontiers Media SA
Page : 137 pages
File Size : 55,7 Mb
Release : 2023-01-05
Category : Medical
ISBN : 9782889763658
Viral pandemics, such as influenza A virus H1N1, Zika virus, and most recently SARS-CoV-2 are becoming more common. Depending on the virus, infection during pregnancy may impart risk for more severe maternal disease, preterm birth, preeclampsia, stillbirth or congenital anomalies. The maternal, placental and fetal immune response is essential for viral clearance. However, viral evasion of host immunity may lead to persistent viremia, placental infection and vertical transmission. There is an urgent need to understand the impact of a wide array of viruses on maternal-fetal immunity, maternal health, pregnancy outcomes and fetal development.
Author : Nandor Gabor Than,Sinuhe Hahn,Simona W. Rossi,Julia Szekeres-Bartho
Publisher : Unknown
Page : 0 pages
File Size : 44,9 Mb
Release : 2020
Category : Electronic
ISBN : OCLC:1368445630
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Author : Raymond W. Redline,Theonia K. Boyd,Drucilla J. Roberts
Publisher : Cambridge University Press
Page : 367 pages
File Size : 45,5 Mb
Release : 2018-08-23
Category : Medical
ISBN : 9781316632536
A guide to identifying disease processes in the placenta affecting pregnancy outcome, with current diagnostic criteria and clinical consequences.
Author : Gil Mor
Publisher : Springer Science & Business Media
Page : 338 pages
File Size : 52,5 Mb
Release : 2007-12-27
Category : Medical
ISBN : 9780387349442
This book covers in detail contemporary hypotheses and studies related to the immunology of implantation and provides a practical approach for the application of basic reproductive immunology research to pregnancy complications such as preeclampsia, pre-term labor and IUGR. Provides complete and up to date review of current knowledge of the role of the immune system during pregnancy and the interactions between the placenta and the maternal immune system.
Author : Gil Mor
Publisher : Academic Press
Page : 462 pages
File Size : 40,9 Mb
Release : 2021-02-12
Category : Medical
ISBN : 9780128189306
Reproductive Immunology: Basic Concepts gives a holistic insight into the understanding of the complex interactions between the maternal immune system and the fetal/placental unit necessary for the success of pregnancy. This interaction is critical for the support of the human fetal semiallograft and the protection against infections. The book covers various topics such as B cells, macrophages, T cells, discussion on fetal signals and their impact on maternal reproductive cells such as endometrial cells, mast cells, and the role of fetal Hofbauer cells, the immune regulatory role of glucorticoids, and many other novel topics within the field of reproductive immunology. Edited and written by experts in the field, this book introduces the up-to-date knowledge of the role of the immune system during pregnancy and provides the necessary background to understand pregnancy complications associated with alterations in the functioning of the immune system. The book provides a complete discussion on the immunological aspects of pregnancy and serves as a great tool for research scientists, students, reproductive immunologists and OBGYNs. Shows the detailed evaluation of the knowledge related to each immune cell type in the pregnant and not pregnant uterus Evaluates each immune cell type and its function during specific reproductive events Provides the biological background for understanding the clinical aspects that will be discussed in subsequent volumes in the series
Author : Cilia Abad,Mariana Farina,Alicia E Damiano,Reinaldo Marín
Publisher : Frontiers Media SA
Page : 264 pages
File Size : 40,9 Mb
Release : 2023-12-18
Category : Medical
ISBN : 9782832541067
Author : Jean W. Keeling,T.Yee Khong
Publisher : Springer Science & Business Media
Page : 888 pages
File Size : 44,6 Mb
Release : 2009-07-11
Category : Medical
ISBN : 9781846287435
The fourth edition of the classic reference in the field of fetal and neonatal pathology, this revised and updated book retains the overall format of previous editions, presenting the same practical approach to the examination of both fetuses and perinatal deaths. It provides essential clinical and pathophysiological information and discusses the pathogenesis of abnormalities as a basis for appropriate methods of investigation. While primarily addressing the morbid anatomist and histopathologist, it is also a valuable resource for obstetricians, neonatologists and paediatricians.
Author : King K. Holmes,Stefano Bertozzi,Barry R. Bloom,Prabhat Jha
Publisher : World Bank Publications
Page : 506 pages
File Size : 47,7 Mb
Release : 2017-11-06
Category : Medical
ISBN : 9781464805257
Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.
Author : Christoph Lees,Gerard H. A. Visser,Kurt Hecher
Publisher : Cambridge University Press
Page : 299 pages
File Size : 53,9 Mb
Release : 2018-08-02
Category : Medical
ISBN : 9781107101395
Master the effective evaluation of placental-fetal growth restriction (PFGR), whilst developing strategies to reduce the risk of perinatal mortality and morbidity in patients worldwide.
Author : Ane C.F. Nunes
Publisher : BoD – Books on Demand
Page : 249 pages
File Size : 51,5 Mb
Release : 2020-01-08
Category : Medical
ISBN : 9781789843576
Inflammation is known worldwide, from the bench to the bedside, but it is a hard theme to approach with one single point of view.In this sense, a selection of translational studies would support the medical-scientific community to better understand the complex network of the inflammatory process, its maintenance, and potential treatment targets. The eleven chapters that compose this book present interesting insights into inflammation and its mechanisms, merging classic background with innovative approaches. From the molecular basis to experimental models, the chapters selected for this book bring to readers at different academic levels updated and practical data on inflammation. Find out what drives interdisciplinary medical research on inflammation and enjoy this informative collection.
