Viruses Immunity And Immunodeficiency

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Viruses, Immunity, and Immunodeficiency

Andor Szentivanyi,Herman Friedman
Viruses Immunity and Immunodeficiency Book PDF

Author : Andor Szentivanyi,Herman Friedman
Publisher : Springer Science & Business Media
Page : 353 pages
File Size : 42,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461321859

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Viruses, Immunity, and Immunodeficiency by Andor Szentivanyi,Herman Friedman Pdf

This publication, "Viruses, Immunity and Immunodeficiency," is based on the first symposium in a series of International Biomedical Symposia sponsored by the College of Medicine of the University of South Florida in Tampa, Florida. There is an explosive interest concerning the effects of viruses on the immune response, especially the immunosuppressive effects of viral infection. This has come about because of the recognition that the Acquired Immunodeficiency Syndrome, which has taken biomedical scientists and the public in general by surprise, is just one of the many examples that viruses can influence the immune response system and, under appropriate circumstances, alter immunity in such a way that an infected individual becomes hi~lly susceptible to a variety of other organisms to which normal individuals would be resistant. This symposium series, sponsored by the University of South Florida College of Medicine, brings to the biomedical con®unity topics of current interest. We thank the members of the faculty of various departments of the College of Medicine and the administration of the College for their support and encouragement in having these symposiaat this medical school. This volume, based or. this symposium onviruses and immunity is a good exam ple of the interdisciplinary nature of modern irrJ!1I1nobiology and modern biomedical science in general. Many investigators with many different back grounds and training experiences, including microbiologists, immunologists, biochemists, oncologists, and physicians, are interested in how and why viruses influence the immune response system.

Viruses, Immunity, and Immunodeficiency

Andor Szentivanyi,Herman Friedman
Viruses Immunity and Immunodeficiency Book PDF

Author : Andor Szentivanyi,Herman Friedman
Publisher : Springer
Page : 365 pages
File Size : 48,6 Mb
Release : 2012-12-27
Category : Medical
ISBN : 1461292867

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Viruses, Immunity, and Immunodeficiency by Andor Szentivanyi,Herman Friedman Pdf

This publication, "Viruses, Immunity and Immunodeficiency," is based on the first symposium in a series of International Biomedical Symposia sponsored by the College of Medicine of the University of South Florida in Tampa, Florida. There is an explosive interest concerning the effects of viruses on the immune response, especially the immunosuppressive effects of viral infection. This has come about because of the recognition that the Acquired Immunodeficiency Syndrome, which has taken biomedical scientists and the public in general by surprise, is just one of the many examples that viruses can influence the immune response system and, under appropriate circumstances, alter immunity in such a way that an infected individual becomes hi~lly susceptible to a variety of other organisms to which normal individuals would be resistant. This symposium series, sponsored by the University of South Florida College of Medicine, brings to the biomedical con®unity topics of current interest. We thank the members of the faculty of various departments of the College of Medicine and the administration of the College for their support and encouragement in having these symposiaat this medical school. This volume, based or. this symposium onviruses and immunity is a good exam ple of the interdisciplinary nature of modern irrJ!1I1nobiology and modern biomedical science in general. Many investigators with many different back grounds and training experiences, including microbiologists, immunologists, biochemists, oncologists, and physicians, are interested in how and why viruses influence the immune response system.

Viral Pathogenesis and Immunity

Neal Nathanson
Viral Pathogenesis and Immunity Book PDF

Author : Neal Nathanson
Publisher : Elsevier
Page : 280 pages
File Size : 44,7 Mb
Release : 2007-04-04
Category : Medical
ISBN : 0080471056

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Viral Pathogenesis and Immunity by Neal Nathanson Pdf

Based on the highly successful reference work Viral Pathogenesis published in 1997, this concise, economical version can be used both as an introductory text or for self-education by medical students and biologists alike. This latest edition provides a completely revised overview of the subject with new chapters on innate immunity, emerging viral diseases, and antiviral therapy in a format that is easy to understand without continually referring to additional information. Used by the author in his graduate classes at the University of Pennsylvania, it sets forth the essential principles and discusses the details of how the immune system responds to viral invasion including the treatment and prevention of infection. Illustrated by pertinent examples it is one of the only books devoted exclusively to this topic. * Offers almost a 20% expansion over the first edition * Focuses specifically on viral pathogenesis unlike other texts where only a few chapters are devoted to the topic * Neal Nathanson is one of the primary authorities in the field and has authored chapters on viral pathogenesis in two of the most well known virology and microbiology titles Field's Virology and Topley and Wilson's Microbiology * Now in four color throughout!

Immunodeficiency and Disease

A.D.B Webster
Immunodeficiency and Disease Book PDF

Author : A.D.B Webster
Publisher : Springer Science & Business Media
Page : 192 pages
File Size : 43,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789400912755

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Immunodeficiency and Disease by A.D.B Webster Pdf

The AIDS epidemic has popularized immune deficiency and has led to a rapid increase in the funding for research into the effect of viruses on immunity. There is now a real possibility of finding out whether some of the rare, so-called 'primary' immunodeficiency syndromes of children and adults, first described in the 1950s, may have a viral aetiology. Most of these syndromes have already been extensively reviewed more than once over the past 10 years, and their diagnosis and management is now included in most standard medical textbooks. In this volume, I have chosen to highlight what I consider to be the potentially exciting aspects of immunodeficiency in humans, hopefully providing clinicians and medical academics with some insight into the recent breakthroughs and disappointments. There are three chapters discussing viral interactions with the immune system. Although much has been written about AIDS already, I make no apology for including an extensive review of both the clinical and laboratory aspects of this disease. AIDS is an important precedent, and it is likely that other less pathogenic retroviruses will eventually turn dut to cause some of the rarer immunodeficiency disorders in children and adults. For instance, it has long been suspected that viruses may cause some of the non-familial types of severe combined immunodeficiency in infants; in fact HIV-I infection now has to be considered in the differential diagnosis.

Neuropathogenic Viruses and Immunity

Steven Specter,Mauro Bendinelli,Herman Friedman
Neuropathogenic Viruses and Immunity Book PDF

Author : Steven Specter,Mauro Bendinelli,Herman Friedman
Publisher : Springer Science & Business Media
Page : 360 pages
File Size : 55,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781468458862

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Neuropathogenic Viruses and Immunity by Steven Specter,Mauro Bendinelli,Herman Friedman Pdf

There has been a tremendous increase in interest in the neuropathogenicity of viruses during the past decade as we have come to recognize that the human immunodeficiency virus, which causes the acquired immunodeficiency syndrome (AIDS), can infect glial cells and cause neurological disease. Yet this increase has not been limited to AIDS but has extended to viruses that infect either or both the central and peripheral nervous systems. The changes examined here include both neurological and psychological diseases or syndromes. Moreover, the chapters in this volume review the interaction of the host immune system with the viruses examined and how such interactions may increase or decrease the neuropatho genicity of the viruses. Questions regarding viral neuropathogenesis include: (I) What is the mode of transmission of virus to the nervous system? (2) What types of cells are infected, and do they contain receptors for the virus? (3) What is the extent of damage that results from viral infection? (4) What are the immunologic mecha nisms by which damage is mediated or limited? Many of these questions remain unanswered, but this volume delves into efforts to provide some answers.

Janeway's Immunobiology

Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter
Janeway s Immunobiology Book PDF

Author : Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter
Publisher : Garland Science
Page : 128 pages
File Size : 46,5 Mb
Release : 2010-06-22
Category : Medical
ISBN : 0815344570

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Janeway's Immunobiology by Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter Pdf

The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Immunodeficiency Disorders

Jordan S. Orange
Immunodeficiency Disorders Book PDF

Author : Jordan S. Orange
Publisher : Unknown
Page : 0 pages
File Size : 44,6 Mb
Release : 2008
Category : Immunological deficiency syndromes
ISBN : 1416058567

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Immunodeficiency Disorders by Jordan S. Orange Pdf

Topics include: "Genetic Diagnosis ofPrimary Immunodeficiencies","IPEX syndrome and Treg deficiency in primaryimmunodeficiency","DiGeorge syndrome and other thymic hypoplasias","Common VariableImmunodeficiency", "Hyper IgE syndromes","Hyper IgM syndromes","Hematophagocyticlymphohistiocytoses", "Defects of the Toll LikeReceptor System", "Congenital Neutropenias", "Advances in Severe Combined Immunodeficiency", "Genetic Defects of Apoptosis and PrimaryImmunodeficiency", "Principles of and Advances inimmunoglobuin replacement therapy for primary immunodeficiency", "Gene therapy for primary immunodeficiency"

Virus Dynamics : Mathematical Principles of Immunology and Virology

Martin Nowak,Robert M. May
Virus Dynamics Mathematical Principles of Immunology and Virology Book PDF

Author : Martin Nowak,Robert M. May
Publisher : Oxford University Press, UK
Page : 253 pages
File Size : 52,5 Mb
Release : 2000-11-23
Category : Electronic
ISBN : 9780191588518

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Virus Dynamics : Mathematical Principles of Immunology and Virology by Martin Nowak,Robert M. May Pdf

This groundbreaking book describes the emerging field of theoretical immunology, in particular the use of mathematical models to describe the spread of infectious diseases within patients. It reveals fascinating insights into the dynamics of viral and other infections, and the interactions between infectious agents and immune responses. Structured around the examples of HIV/AIDS and hepatitis B, Nowak and May show how mathematical models can help researchers to understand the detailed dynamics of infection and the effects of antiviral therapy. Models are developed to describe the dynamics of drug resistance, immune responses, viral evolution and mutation, and to optimise the design of therapy and vaccines. - ;We know, down to the tiniest details, the molecular structure of the human immunodeficiency virus (HIV). Yet despite this tremendous accomplishment, and despite other remarkable advances in our understanding of individual viruses and cells of the immune system, we still have no agreed understanding of the ultimate course and variability of the pathogenesis of AIDS. Gaps in our understanding like these impede our efforts towards developing effective therapies and preventive vaccines. Martin Nowak and Robert M May describe the emerging field of theoretical immunology in this accessible and well- written text. Using mathematical modelling techniques, the authors set out their ideas about how populations of viruses and populations of immune system cells may interact in various circumstances, and how infectious diseases spread within patients. They explain how this approach to understanding infectious diseases can reveal insights into the dynamics of viral and other infections, and the interactions between infectious agents and immune responses. The book is structured around the examples of HIV/AIDS and Hepatitis B virus, although the approaches described will be more widely applicable. The authors use mathematical tools to uncover the detailed dynamics of the infection and the effects of antiviral therapy. Models are developed to describe the emergence of drug resistance, and the dynamics of immune responses, viral evolution, and mutation. The practical implications of this work for optimisation of the design of therapy and vaccines are discussed. The book concludes with a glance towards the future of this fascinating, and potentially highly useful, field of study. - ;... an excellent introduction to a field that has the potential to advance substantially our understanding of the complex interplay between virus and host - Nature

Persistent Viral Infections

R. Ahmed,Irvin Chen
Persistent Viral Infections Book PDF

Author : R. Ahmed,Irvin Chen
Publisher : Wiley-Blackwell
Page : 754 pages
File Size : 47,8 Mb
Release : 1999
Category : Medical
ISBN : UOM:39015041993448

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Persistent Viral Infections by R. Ahmed,Irvin Chen Pdf

Persistent Viral Infections Edited by Rafi Ahmed Emory Vaccine Center, Atlanta, USA and Irvin S. Y. Chen UCLA School of Medicine, Los Angeles, USA During the past decade much of our attention has focused on diseases associated with viral persistence. Major breakthroughs in immunology, and the advent of molecular approaches to study pathogenesis have increased our understanding of the complex virus-host interactions that occur during viral persistence. Persistent Viral Infections focuses on: * The pathogenesis and immunology of chronic infections * Animal models that provide, or have the potential to provide, major insights This volume will be essential reading for virologists, immunologists, oncologists and neurologists.

Chimpanzees in Biomedical and Behavioral Research

National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Institute of Medicine,Board on Health Sciences Policy,Committee on the Use of Chimpanzees in Biomedical and Behavioral Research
Chimpanzees in Biomedical and Behavioral Research Book PDF

Author : National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Institute of Medicine,Board on Health Sciences Policy,Committee on the Use of Chimpanzees in Biomedical and Behavioral Research
Publisher : National Academies Press
Page : 200 pages
File Size : 54,9 Mb
Release : 2012-01-05
Category : Science
ISBN : 9780309220392

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Chimpanzees in Biomedical and Behavioral Research by National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Institute of Medicine,Board on Health Sciences Policy,Committee on the Use of Chimpanzees in Biomedical and Behavioral Research Pdf

For many years, experiments using chimpanzees have been instrumental in advancing scientific knowledge and have led to new medicines to prevent life-threatening and debilitating diseases. However, recent advances in alternate research tools have rendered chimpanzees largely unnecessary as research subjects. The Institute of Medicine, in collaboration with the National Research Council, conducted an in-depth analysis of the scientific necessity for chimpanzees in NIH-funded biomedical and behavioral research. The committee concludes that while the chimpanzee has been a valuable animal model in the past, most current biomedical research use of chimpanzees is not necessary, though noted that it is impossible to predict whether research on emerging or new diseases may necessitate chimpanzees in the future.

Viruses that Affect the Immune System

Hung Fan
Viruses that Affect the Immune System Book PDF

Author : Hung Fan
Publisher : ASM Press
Page : 272 pages
File Size : 44,8 Mb
Release : 1991
Category : HIV
ISBN : UOM:39015025206387

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Viruses that Affect the Immune System by Hung Fan Pdf

From a March 1990 conference in Newport Beach, California, 16 papers explore the effect of retroviruses and herpes viruses on the immune systems of mice and men. They cover autoimmunity, immunodeficiency, and oncogenesis induced by the viruses, discussing such topics as regulatory genes, cellular proteins, molecular genetics, immortalization of lymphocytes, and various findings on HIV and leukemia. The price is $45 for members of the society. Annotation copyrighted by Book News, Inc., Portland, OR

Case Studies in Immunology

Raif Geha,FRED Rosen
Case Studies in Immunology Book PDF

Author : Raif Geha,FRED Rosen
Publisher : Garland Science
Page : 353 pages
File Size : 48,5 Mb
Release : 2010-07-29
Category : Medical
ISBN : 9781135153069

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Case Studies in Immunology by Raif Geha,FRED Rosen Pdf

This book presents case histories to illustrate in a clinical context essential points about the mechanisms of immunity. It includes cases that illustrate both recently discovered genetic immunodeficiencies and some more familiar and common diseases with interesting immunology.

The Human Immunodeficiency Virus

Emilio Emini
The Human Immunodeficiency Virus Book PDF

Author : Emilio Emini
Publisher : Princeton University Press
Page : 546 pages
File Size : 46,9 Mb
Release : 2021-04-13
Category : Medical
ISBN : 9780691228839

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The Human Immunodeficiency Virus by Emilio Emini Pdf

The past few years have witnessed an explosive increase in our collective knowledge of the biology of the human immunodeficiency virus (HIV). Researchers have acquired new understanding of the virus's biochemistry, molecular biology, pathogenesis, genetics, and immunobiology. Resulting therapeutic advances have significantly prolonged the lives of thousands. Yet, the need to develop better therapies is ever more acute and--given the virus's continued spread through the human population--the need for an effective vaccine is urgent. These goals can be accomplished only through the experienced synthesis of information from the many disciplines participating in HIV research and through the insights of new investigators. This volume is designed to lower the barriers imposed on investigators by the sheer volume of available information--information that often can be found only in far-flung and specialized journals. It provides, in a single resource, an in-depth overview of the diverse areas that constitute HIV research. The result is a broad introduction for students and researchers new to the field as well as an integrated overview for researchers specialized in particular areas of HIV investigation. The volume will also benefit those seeking technical understanding of the virus's biology, including physicians treating HIV-infected patients. Each chapter is a comprehensive presentation of one area of current AIDS research--including work on the virus life cycle, epidemiology, genetics, protease and reverse transcriptase inhibitors, receptor and co-receptor interactions, therapeutic targets, clinical treatment, immunobiology, and vaccines--written by a leading researcher in that area. The contributors are Jon P. Anderson, Jan Balzarini, Elana Cherry, Thomas J. Coates, Chris Collins, Jon H. Condra, Mark B. Feinberg, Richard B. Gaynor, Matthias Götte, Daria J. Hazuda, Spyros Kalams, Nathaniel R. Landau, Gerald H. Learn, Norman L. Letvin, James I. Mullins, Willscott E. Naugler, David Nickle, Matthew Rain, Allen G. Rodrigo, Daniel Shriner, Shalom Spira, Mario Stevenson, Todd Summers, Catherine Ulich, Joseph P. Vacca, Mark A. Wainberg, Bruce D. Walker, and Yang Wang.

Asthma

Richard F. Lockey,Dennis K. Ledford
Asthma Book PDF

Author : Richard F. Lockey,Dennis K. Ledford
Publisher : Oxford University Press, USA
Page : 513 pages
File Size : 44,5 Mb
Release : 2014
Category : Medical
ISBN : 9780199918065

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Asthma by Richard F. Lockey,Dennis K. Ledford Pdf

Diagnosing asthma requires knowledge of the multiple conditions that emulate it, and treatment requires addressing factors that modify the disease. This comprehensive, single reference will help practitioners identify and care for co-morbid conditions and improve asthma treatment.

Virus-Induced Immunosuppression

Steven Specter,Mauro Bendinelli,Herman Friedman
Virus Induced Immunosuppression Book PDF

Author : Steven Specter,Mauro Bendinelli,Herman Friedman
Publisher : Springer Science & Business Media
Page : 486 pages
File Size : 49,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781468455830

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Virus-Induced Immunosuppression by Steven Specter,Mauro Bendinelli,Herman Friedman Pdf

It is now widely acknowledged that at the beginning of this century Claude von Pirquet first pointed out that a viral disease, i. e. , measles, resulted in an anergy or depression of preexisting immune response, namely, delayed continuous hypersensitivity to PPD derived from Mycobacterium tuberculosis. Thereafter ob servations that viral infections may result in immunosuppression have been recorded by many clinicians and infectious disease investigators for six or seven decades. Nevertheless, despite sporadic reports that infectious diseases caused by viruses may result in either transient or prolonged immunodepression, investigation of this phenomenon languished until the mid-1960s, when it was pointed out that a number of experimental retroviral infections of mice with tumor viruses may result in marked immunosuppression. However, it was not until the recognition of the new epidemic of acquired immunodeficiency syn drome (AIDS) caused by the human immunodeficiency virus and related vi ruses that acquired immunodeficiencies associated with virus infection became general knowledge among biomedical investigators as well as the lay public. A number of reviews published during the past decade or so pointed out that numerous viruses may affect humoral and cellular immune responses. Furthermore, expanding knowledge about the nature and mechanisms of both humoral and cellular immunity and pathogenesis of viral infections has pro vided clinical and experimental models for investigating in depth how and why viruses of man and animals profoundly affect immune responses.