What You Need To Know About An Evolutionary Technique Of Mitochondrial Replacement Therapy Mrt A K A Mitochondrial Donation Technique A Concise Review

Author : Dr. Hakim. K. Saboowala
Publisher : Dr.Hakim Saboowala
Page : 46 pages
File Size : 42,5 Mb
Release : 2024-06-16
Category : Medical
ISBN : 8210379456XXX

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What you need to know about an Evolutionary Technique of “Mitochondrial Replacement Therapy(MRT)” a.k.a. “Mitochondrial Donation technique”: A Concise Review. by Dr. Hakim. K. Saboowala Pdf

What you need to know about an Evolutionary Technique of “Mitochondrial Replacement Therapy(MRT)” a.k.a. “Mitochondrial Donation technique”: A Concise Review. Mitochondrial Replacement Therapy also referred to as “Mitochondrial Donation technique” pertains to the category of techniques in which the embryo possessing the nuclear DNA of the parents is subjected to the IVF procedure to have mitochondrial DNA of the donor female. In this era of advanced scientific technologies, MRT aims to treat the infecundity of the diseased females and provide them a suitable chance to have biologically related healthy offspring Mitochondrial replacement therapy (MRT) is a new form of reproductive in vitro fertilization (IVF) which works on the principle of replacing a women's abnormal mitochondrial DNA (mt-DNA) with the donor's healthy one. MRT include different techniques like: § Spindles transfer (ST), § Pronuclear transfer (PNT) or § Polar body transfer (PBT). Transmission of defective mitochondrial DNA to the next generation can also be prevented by using these approaches. The development of healthy baby free from genetic disorders and to terminate the lethal mitochondrial disorders are the chief motive of this technique. However, moral, social, and cultural objections have restricted its exploration. Therefore, it is attempted in this E-Booklet to summarize: · The various methods involved in MRT, · The global status, and · The exaggerated censure over the years which depicts a strong emphasis for social acceptance and clinical application in the world of medical science along with few relevant Illustrations for better understanding the subject at Molecular Level. …Dr. H. K. Saboowala. M.B.(Bom) .M.R.S.H.(London)

Author : Peter Kokkinos,Puneet Narayan
Publisher : Springer
Page : 443 pages
File Size : 40,9 Mb
Release : 2019-03-18
Category : Medical
ISBN : 9783030048167

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Cardiorespiratory Fitness in Cardiometabolic Diseases by Peter Kokkinos,Puneet Narayan Pdf

This book examines the links between physical activity (PA), cardiorespiratory fitness (CRF), and cardiovascular and metabolic diseases. It presents an overview of the role of PA and CRF in the prevention and management of risk factors associated with cardiometabolic diseases such as hypertension, peripheral vascular disease, stroke, type 2 diabetes, metabolic syndrome, dyslipidemia, obesity, and atherosclerosis. In addition, it explores how these risks vary with different populations such as the elderly and people of various racial backgrounds. The book also highlights risks associated with exercise and presents a prescription for appropriate and efficacious exercise to minimize risk and maximize health benefits for the heart. Cardiorespiratory Fitness in Prevention and Management of Cardiometabolic Disease is an essential resource for physicians, exercise physiologists, medical students, residents, fellows, nurses, and researchers in cardiology, cardiorespiratory fitness, exercise science, health promotion and disease prevention, public health, and epidemiology.

Author : Jud G. Isebrands,Jim Richardson
Publisher : CABI
Page : 700 pages
File Size : 50,8 Mb
Release : 2014-02-12
Category : Technology & Engineering
ISBN : 9781780641089

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Poplars and Willows by Jud G. Isebrands,Jim Richardson Pdf

Poplars and willows form an important component of forestry and agricultural systems, providing a wide range of wood and non-wood products. This book synthesizes research on poplars and willows, providing a practical worldwide overview and guide to their basic characteristics, cultivation and use, issues, problems and trends. Prominence is given to environmental benefits and the importance of poplar and willow cultivation in meeting the needs of people and communities, sustainable livelihoods, land use and development.

Author : Pons Batugal
Publisher : Bioversity International
Page : 797 pages
File Size : 50,7 Mb
Release : 2005
Category : Coconut
ISBN : 9789290436294

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Coconut Genetic Resources by Pons Batugal Pdf

Author : Erno Sajo,Piotr Zygmansk
Publisher : Unknown
Page : 128 pages
File Size : 55,8 Mb
Release : 2020
Category : MEDICAL
ISBN : 0750323957

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Nanoparticle Enhanced Radiation Therapy by Erno Sajo,Piotr Zygmansk Pdf

Improved targeting of abnormal cells and tissue in the radiotherapy of cancer has been a long-standing goal of researchers. The central purpose in Nanoparticle-Enhanced Radiotherapy (NPRT) is to more precisely control where the radiation dose is delivered, desirably with subcellular precision, provided we can find a method to bring the nanoparticles to target and control their concentration and size distribution. The contents within this book will cover the rationale and fundamental principles of NPRT, optimal nanoparticle sizes, concentrations, design and fabrication, effective nanoparticle delivery methods, emerging clinical applications of NRT modalities, treatment planning and quality assurance and the potential of NPRT in global health. This volume will serve as a resource for researchers, educators and industry, and as a practical guide or comprehensive reference for students, research trainees and others working in cancer nanomedicine. Part of IOP Series in Global Health and Radiation Oncology.

Author : Vasili Tsakanov,Helmut Wiedemann
Publisher : Springer Science & Business Media
Page : 484 pages
File Size : 52,7 Mb
Release : 2007-03-31
Category : Medical
ISBN : 9781402057229

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Brilliant Light in Life and Material Sciences by Vasili Tsakanov,Helmut Wiedemann Pdf

This book contains an excellent overview of the status and highlights of brilliant light facilities and their applications in biology, chemistry, medicine, materials and environmental sciences. Overview papers on diverse fields of research by leading experts are accompanied by the highlights in the near and long-term perspectives of brilliant X-Ray photon beam usage for fundamental and applied research.

Author : B. Venkateswarlu,Arun K. Shanker,Chitra Shanker,M. Maheswari
Publisher : Springer Science & Business Media
Page : 612 pages
File Size : 53,7 Mb
Release : 2011-11-22
Category : Technology & Engineering
ISBN : 9400722206

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Crop Stress and its Management: Perspectives and Strategies by B. Venkateswarlu,Arun K. Shanker,Chitra Shanker,M. Maheswari Pdf

Crops experience an assortment of environmental stresses which include abiotic viz., drought, water logging, salinity, extremes of temperature, high variability in radiation, subtle but perceptible changes in atmospheric gases and biotic viz., insects, birds, other pests, weeds, pathogens (viruses and other microbes). The ability to tolerate or adapt and overwinter by effectively countering these stresses is a very multifaceted phenomenon. In addition, the inability to do so which renders the crops susceptible is again the result of various exogenous and endogenous interactions in the ecosystem. Both biotic and abiotic stresses occur at various stages of plant development and frequently more than one stress concurrently affects the crop. Stresses result in both universal and definite effects on plant growth and development. One of the imposing tasks for the crop researchers globally is to distinguish and to diminish effects of these stress factors on the performance of crop plants, especially with respect to yield and quality of harvested products. This is of special significance in view of the impending climate change, with complex consequences for economically profitable and ecologically and environmentally sound global agriculture. The challenge at the hands of the crop scientist in such a scenario is to promote a competitive and multifunctional agriculture, leading to the production of highly nourishing, healthy and secure food and animal feed as well as raw materials for a wide variety of industrial applications. In order to successfully meet this challenge researchers have to understand the various aspects of these stresses in view of the current development from molecules to ecosystems. The book will focus on broad research areas in relation to these stresses which are in the forefront in contemporary crop stress research.

Author : Surinder Kumar Gupta
Publisher : Academic Press
Page : 582 pages
File Size : 52,8 Mb
Release : 2015-09-25
Category : Technology & Engineering
ISBN : 9780128014691

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Breeding Oilseed Crops for Sustainable Production by Surinder Kumar Gupta Pdf

Breeding Oilseed Crops for Sustainable Production: Opportunities and Constraints presents key insights into accelerating the breeding of sustainable and superior varieties. The book explores the genetic engineering/biotechnology that has played a vital role in transforming economically important traits from distant/wild species to cultivated varieties, enhancing the quality and quantity of oil and seed yield production. Integrated nutrient management, efficient water management, and forecasting models for pests diseases outbreaks and integrated pest and pest management have also added new dimensions in breeding for sustainable production. With the rise in demand, the scientific community has responded positively by directing a greater amount of research towards sustainable production both for edible and industrial uses. Covering the latest information on various major world oil crops including rapeseed mustard, sunflower, groundnut, sesame, oilpalm, cotton, linseed/flax, castor and olive, this book brings the latest advances together in a single volume for researchers and advanced level students. Describes various methods and systems to achieve sustainable production in all major oilseed crops Addresses breeding, biology and utilization aspects simultaneously including those species whose information is not available elsewhere Includes information on modern biotechnological and molecular techniques and production technologies Relevant for international government, industrial and academic programs in research and development

Author : Stefan Ioan Voicu,Marian Miculescu
Publisher : MDPI
Page : 184 pages
File Size : 48,8 Mb
Release : 2021-03-25
Category : Science
ISBN : 9783036507644

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Advanced Composite Biomaterials by Stefan Ioan Voicu,Marian Miculescu Pdf

Biomaterials is currently one of the most important fields of study. This is because of the high degree of interdisciplinarity and the many practical solutions it provides in relation to medicine, biology, chemistry, and physics. This Special Issue provides readers with research from the domain of composite biomaterials in different applications, from controlled drug release systems to tissue engineering.

Author : Bhupinder Singh
Publisher : CRC Press
Page : 465 pages
File Size : 55,9 Mb
Release : 2018-11-19
Category : Science
ISBN : 9781351139267

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NanoAgroceuticals & NanoPhytoChemicals by Bhupinder Singh Pdf

This book volume encompasses the recent trends made in the applications of nanoscale tools for diverse constituents of plants and agriculture, particularly in addressing the critical issues related to their safety, efficacy, and efficient and cost-efficient development and production.

Author : Anonim
Publisher : Academic Press
Page : 588 pages
File Size : 52,9 Mb
Release : 2014-06-25
Category : Science
ISBN : 9780124202016

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Quantitative Imaging in Cell Biology by Anonim Pdf

This new volume, number 123, of Methods in Cell Biology looks at methods for quantitative imaging in cell biology. It covers both theoretical and practical aspects of using optical fluorescence microscopy and image analysis techniques for quantitative applications. The introductory chapters cover fundamental concepts and techniques important for obtaining accurate and precise quantitative data from imaging systems. These chapters address how choice of microscope, fluorophores, and digital detector impact the quality of quantitative data, and include step-by-step protocols for capturing and analyzing quantitative images. Common quantitative applications, including co-localization, ratiometric imaging, and counting molecules, are covered in detail. Practical chapters cover topics critical to getting the most out of your imaging system, from microscope maintenance to creating standardized samples for measuring resolution. Later chapters cover recent advances in quantitative imaging techniques, including super-resolution and light sheet microscopy. With cutting-edge material, this comprehensive collection is intended to guide researchers for years to come. Covers sections on model systems and functional studies, imaging-based approaches and emerging studies Chapters are written by experts in the field Cutting-edge material

Author : Claudia Parvanta,Sarah Bass
Publisher : Jones & Bartlett Learning
Page : 1054 pages
File Size : 54,5 Mb
Release : 2018-08-27
Category : Education
ISBN : 9781284175028

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Health Communication: Strategies and Skills for a New Era by Claudia Parvanta,Sarah Bass Pdf

Health Communication: Strategies and Skills for a New Era provides a practical process model for developing a health communication intervention. The book also explores exposure to media and how it shapes our conceptions of health and illness. Using a life stages and environments approach, the book touches on the patient role and how we ‘hear’ information from health care providers as well as guidance on how to be a thoughtful consumer of health information.

Author : Olena Fesenko,Leonid Yatsenko
Publisher : Springer
Page : 473 pages
File Size : 46,5 Mb
Release : 2019-07-31
Category : Science
ISBN : 9783030177553

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Nanophotonics, Nanooptics, Nanobiotechnology, and Their Applications by Olena Fesenko,Leonid Yatsenko Pdf

This book highlights some of the latest advances in nanotechnology and nanomaterials from leading researchers in Ukraine, Europe, and beyond. It features contributions from participants in the 6th International Science and Practice Conference Nanotechnology and Nanomaterials (NANO2018) in Kiev, Ukraine on August 27-30, 2018 organized by the Institute of Physics of the National Academy of Sciences of Ukraine, University of Tartu (Estonia), University of Turin (Italy), and Pierre and Marie Curie University (France). Internationally recognized experts from a wide range of universities and research institutions share their knowledge and key results on nanooptics, energy storage and biomedical applications. This book's companion volume also addresses topics such as materials properties, behavior, and synthesis.

Author : Tapan Kumar Mondal
Publisher : Springer Science & Business Media
Page : 167 pages
File Size : 51,7 Mb
Release : 2014-02-10
Category : Science
ISBN : 9788132217046

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Breeding and Biotechnology of Tea and its Wild Species by Tapan Kumar Mondal Pdf

Tea is an important non-alcoholic beverage plant of the world. Cultivation of tea is very important as it earns revenue for the tea growing nations especially the developing countries such as India. Although conventional breeding is well-established and has contributed significantly for varietal improvement of this plant and other Camellia species with ornamental value, yet applications of biotechnology are required to intervene some of the issues where conventional breeding is restricted particularly for woody plants such as tea. It is note-worthy to mention that some amounts of biotechnology works in several facets of tea and its wild species have also been done. In the present book, a state-of-the-art on various aspects of breeding and biotechnology has been complied in eight chapters. They are: i) Origin and descriptions of health benefits as well as morphological classification as first chapter, ii) Breeding and cytogenetics that comprise with various conventional approaches of varietal improvement of tea along with their genetic resources, iii) Micropropagation which deals with in-depth study of clonal propagation, iv) Somatic embryogenesis along with alternative techniques such as suspension culture, cry-preservation etc. v) Molecular breeding that deals with application of various DNA-based markers, linkage map etc., vi) Genetic transformation and associated factors, vii) Stress physiology complied with various works done in tea along with its wild relatives on abiotic as well as biotic stress, and viii) Functional genomics that describe the various works of molecular cloning and characterizations, differential gene expression, high-throughput sequencing, bioinformatics etc. Importantly, the author has made exclusive tables in most of the chapters that include the summary of the works in particular topic. In a nutshell, the book compiles the work already been done, identifies the problems, analyzes the gaps on breeding and biotechnological works of tea as well as its wild species and discusses the future scope as conclusion. Every effort has been made to include all the published works till June 2013. The book will be a useful resource for post-graduate, doctoral as well post-doctoral students working on tea as well as other woody plants. This will also be useful for the scientists working in the areas of life sciences, genomics, biotechnology and molecular biology.

Author : Yingwei Peng,Binbing Yu
Publisher : CRC Press
Page : 268 pages
File Size : 51,7 Mb
Release : 2021-03-22
Category : Mathematics
ISBN : 9780429629686

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Cure Models by Yingwei Peng,Binbing Yu Pdf

Cure Models: Methods, Applications and Implementation is the first book in the last 25 years that provides a comprehensive and systematic introduction to the basics of modern cure models, including estimation, inference, and software. This book is useful for statistical researchers and graduate students, and practitioners in other disciplines to have a thorough review of modern cure model methodology and to seek appropriate cure models in applications. The prerequisites of this book include some basic knowledge of statistical modeling, survival models, and R and SAS for data analysis. The book features real-world examples from clinical trials and population-based studies and a detailed introduction to R packages, SAS macros, and WinBUGS programs to fit some cure models. The main topics covered include the foundation of statistical estimation and inference of cure models for independent and right-censored survival data, cure modeling for multivariate, recurrent-event, and competing-risks survival data, and joint modeling with longitudinal data, statistical testing for the existence and difference of cure rates and sufficient follow-up, new developments in Bayesian cure models, applications of cure models in public health research and clinical trials.