Who Manual For Hiv Drug Resistance Testing Using Dried Blood Spot Specimens

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HIV drug resistance strategy, 2021 update

Author : Anonim
Publisher : World Health Organization
Page : 36 pages
File Size : 47,5 Mb
Release : 2020-07-23
Category : Medical
ISBN : 9789240030565

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HIV drug resistance strategy, 2021 update by Anonim Pdf

Laboratory-based survey of acquired HIV drug resistance using remnant viral load specimens

Author : Anonim
Publisher : World Health Organization
Page : 91 pages
File Size : 45,7 Mb
Release : 2021-06-29
Category : Medical
ISBN : 9789240025417

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Laboratory-based survey of acquired HIV drug resistance using remnant viral load specimens by Anonim Pdf

WHO’s laboratory-based acquired drug resistance survey method yields robust estimates of acquired HIV drug resistance in adults, children and adolescents taking both dolutegravir and non-dolutegravir based regimens by genotyping remnant specimens from routine viral load testing. Results are used to inform programme decision making regarding optimal ART regimens and support evaluation of programme quality with respect to maximizing viral load suppression and minimizing emergence of resistance in people taking ART.

Dried Blood Spots

Author : Wenkui Li,Mike S. Lee
Publisher : John Wiley & Sons
Page : 711 pages
File Size : 55,7 Mb
Release : 2014-05-21
Category : Science
ISBN : 9781118890899

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Dried Blood Spots by Wenkui Li,Mike S. Lee Pdf

An informative and comprehensive book on the applications and techniques of dried blood spot sampling Dried blood spot (DBS) sampling involves the collection of a small volume of blood, via a simple prick or other means, from a study subject onto a cellulose or polymer paper card, which is followed by drying and transfer to the laboratory for analysis. For many years, this method of blood sample collection has been extensively utilized in some important areas of human healthcare (for example, newborn screening for inherited metabolic disorders and HIV-related epidemiological studies). Because of its advantages over conventional blood, plasma, or serum sample collection, DBS sampling has been valued by the pharmaceutical industry in drug research and development. Dried Blood Spots: Applications and Techniques features contributions from an international team of leading scientists in the field. Their contributions present a unique resource on the history, principles, procedures, methodologies, applications, and emerging technologies related to DBS. Presented in three parts, the book thoroughly examines: Applications of DBS sampling and associated procedures and methodologies in various human healthcare studies Applications and perspectives of DBS sampling in drug research and development, and therapeutic drug monitoring New technologies and emerging applications related to DBS sampling and analysis Dried Blood Spots: Applications and Techniques is a valuable working guide for researchers, professionals, and students in healthcare, medical science, diagnostics, clinical chemistry, and pharmaceuticals, etc.

Laboratory and point-of-care diagnostic testing for sexually transmitted infections, including HIV

Author : World Health Organization
Publisher : World Health Organization
Page : 308 pages
File Size : 45,6 Mb
Release : 2023-11-20
Category : Medical
ISBN : 9789240077089

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Laboratory and point-of-care diagnostic testing for sexually transmitted infections, including HIV by World Health Organization Pdf

The WHO laboratory manual provides microbiologists and medical technologists with an up-to- date comprehensive guide on how to isolate, detect, and diagnose STIs, including HIV. The scope of the manual has been expanded to include chapters on the use of molecular tests, rapid point-of-care tests, and quality management of diagnostic tests and hence the manual will also be of interest to STI and HIV programme managers and clinical staff.

Therapeutic Drug Monitoring

Author : Amitava Dasgupta
Publisher : Elsevier
Page : 580 pages
File Size : 40,9 Mb
Release : 2024-04-26
Category : Medical
ISBN : 9780443186509

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Therapeutic Drug Monitoring by Amitava Dasgupta Pdf

Therapeutic Drug Monitoring 2nd Edition is an updated reference on TDM analytical techniques in diverse clinical settings. This new edition reviews the exciting new developments in the area, including seven new chapters covering immunoassay design and applications, combined chromatographic techniques in therapeutic monitoring, drug monitoring in alternative specimens, pharmacogenomics of anticancer drugs, pharmacogenomics testing for patient management, selected antifungal agents, pharmacodynamic monitoring, and therapeutic drug monitoring of selected anticoagulants. All remaining chapters in the first edition were thoroughly revised and updated. Therapeutic Drug Monitoring 2nd Edition is the ideal reference for clinical pathologists, pharmacologists, and toxicologists involved with TDM. Scientists working in diagnostic companies, developing reagents for monitoring therapeutic drugs will also find relevant information in this book. Includes new chapters covering antifungal, anticoagulant, and anticancer drugs monitoring Discusses limitations of current immunoassays, new and sophisticated chromatographic techniques, the clinical effectiveness of newer antiretroviral agents, anticonvulsants and antidepressants Provides full coverage of pharmacogenomics and personalized medicine, principles of pharmacokinetics and pharmacodynamics, and the application of biomarkers in TDM

Clinical Virology Manual

Author : Richard L. Hodinka,Stephen A. Young,Benjamin A. Pinksy
Publisher : John Wiley & Sons
Page : 622 pages
File Size : 46,6 Mb
Release : 2020-07-10
Category : Medical
ISBN : 9781555819156

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Clinical Virology Manual by Richard L. Hodinka,Stephen A. Young,Benjamin A. Pinksy Pdf

The definitive clinical virology resource for physicians and clinical laboratory virologists The clinical virology field is rapidly evolving and, as a result, physicians and clinical laboratory virologists must have a reliable reference tool to aid in their ability to identify and diagnose viral infections to prevent future outbreaks. In this completely revised edition of the Clinical Virology Manual, Editor in Chief, Michael Loeffelholz, along with Section Editors, Richard Hodinka, Benjamin Pinsky, and Stephen Young, have complied expert perspectives of a renowned team of clinical virology experts and divided these contributions into three sections to provide the latest information on the diagnosis of viral infections, including ebola, HIV and Human papillomavirus state of the art diagnostic technologies, including next-generation sequencing and nucleic acid amplification methods taxonomy of clinically important viruses such as polyomaviruses and zoonotic viruses This comprehensive reference also includes three appendices with vital information on reference virology laboratories at the Centers for Disease Control and Prevention, state and local public health laboratories, and international reference laboratories and laboratory systems. Additionally, a new section "Diagnostic Best Practices," which summarizes recommendations for diagnostic testing, and cites evidence-based guidelines, is included in each viral pathogens chapter. Clinical Virology Manual, Fifth Edition serves as a reference source to healthcare professionals and laboratorians in providing clinical and technical information regarding viral diseases and the diagnosis of viral infections.

Target product profile for HIV drug resistance tests in low- and middle-income countries: Africa

Author : World Health Organization
Publisher : World Health Organization
Page : 30 pages
File Size : 55,9 Mb
Release : 2023-09-12
Category : Medical
ISBN : 9789240076662

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Target product profile for HIV drug resistance tests in low- and middle-income countries: Africa by World Health Organization Pdf

HIV-1 drug resistance tests may be useful tools for optimizing ART regimens when used in the context of information about viral load, immune and clinical status, adherence practices and available treatment options. Several types of drug resistance tests are available, either as commercial kits or based on published methods for in-house assays. The target product profile for HIV drug resistance tests in low- and middle-income countries: Africa is designed to guide the development of new HIV drug resistance tests in the era of dolutegravir-based antiretroviral therapy (ART) and to facilitate the evaluation of the suitability of currently available HIV drug resistance tests for specific applications. The target product profiles focus on the new-term future for available ART regimens and their use and anticipates an innovate test that will meet the projected demand.

Manual of Commercial Methods in Clinical Microbiology

Author : Anonim
Publisher : John Wiley & Sons
Page : 616 pages
File Size : 50,8 Mb
Release : 2016-03-28
Category : Science
ISBN : 9781119021841

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Manual of Commercial Methods in Clinical Microbiology by Anonim Pdf

The Manual of Commercial Methods in Clinical Microbiology 2nd Edition, International Edition reviews in detail the current state of the art in each of the disciplines of clinical microbiology, and reviews the sensitivities, specificities and predictive values, and subsequently the effectiveness, of commercially available methods – both manual and automated. This text allows the user to easily summarize the available methods in any particular field, or for a specific pathogen – for example, what to use for an Influenza test, a Legionella test, or what instrument to use for identification or for an antibiotic susceptibility test. The Manual of Commercial Methods in Clinical Microbiology, 2nd Edition, International Edition presents a wealth of relevant information to clinical pathologists, directors and supervisors of clinical microbiology, infectious disease physicians, point-of-care laboratories, professionals using industrial applications of diagnostic microbiology and other healthcare providers. The content will allow professionals to analyze all commercially available methods to determine which works best in their particular laboratory, hospital, clinic, or setting. Updated to appeal to an international audience, The Manual of Commercial Methods in Clinical Microbiology, 2nd Edition, International Edition is an invaluable reference to those in the health science and medical fields.