Who Think Tank Meeting On Optimizing Antiretroviral Therapy
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WHO Think-tank Meeting on Optimizing AntiRetroviral Therapy by Anonim Pdf
On 12th March 2020, WHO organized a think-tank meeting with people living with HIV, academics, researchers and key stakeholders to identify the most important research questions that need prioritisation to better understand the safety of new antiretroviral drugs for the treatment of HIV, interventions to prevent interruption of treatment during the scale-up of HIV treatment programmes, and highlight critical gaps in knowledge.
Author : World Health Organization Publisher : World Health Organization Page : 44 pages File Size : 52,7 Mb Release : 2024-05-14 Category : Medical ISBN : 9789240093386
WHO think tank on treatment optimization of HIV by World Health Organization Pdf
This report reviews key clinical trials, observational studies, and programmatic data on newer antiretrovirals to inform future updates to global HIV treatment policies. The report also reviewed the latest data on the safety and efficacy of dolutegravir, tenofovir alafenamide, and long-acting ARV-containing regimens in people living with HIV, including pregnant women. Critical gaps in clinical knowledge, research, monitoring, and surveillance on the transition to these new antiretrovirals were discussed, and future research priorities were summarized. The primary audience for this report includes national HIV program managers, clinicians, and healthcare providers. This document will also be of interest to treatment advisory boards, international agencies and organizations that provide technical and financial support to HIV programmes.
Author : World Health Organization Publisher : World Health Organization Page : 23 pages File Size : 42,8 Mb Release : 2022-07-26 Category : Medical ISBN : 9789240053335
Author : World Health Organization Publisher : World Health Organization Page : 34 pages File Size : 54,8 Mb Release : 2022-06-30 Category : Medical ISBN : 9789240053038
Updated recommendations on HIV prevention, infant diagnosis, antiretroviral initiation and monitoring by Anonim Pdf
These guidelines provide new and updated recommendations on the use of point-of-care testing in children under 18 months of age and point-of-care tests to monitor treatment in people living with HIV; the treatment monitoring algorithm; and timing of antiretroviral therapy (ART) among people living with HIV who are being treated for tuberculosis. WHO is currently in the process of collating all HIV normative guidance developed since 2016 in order to publish the third edition of the consolidated HIV guidelines in July 2021. This updated version will include the new clinical guidance presented here.
Consolidated Guidelines on the Use of Antiretroviral Drugs for Treating and Preventing HIV Infection by World Health Organization Pdf
These guidelines provide guidance on the diagnosis of human immunodeficiency virus (HIV) infection, the use of antiretroviral (ARV) drugs for treating and preventing HIV infection and the care of people living with HIV. They are structured along the continuum of HIV testing, prevention, treatment and care. This edition updates the 2013 consolidated guidelines on the use of antiretroviral drugs following an extensive review of evidence and consultations in mid-2015, shared at the end of 2015, and now published in full in 2016. It is being published in a changing global context for HIV and for health more broadly.
Author : World Health Organization Publisher : World Health Organization Page : 592 pages File Size : 55,5 Mb Release : 2021-07-16 Category : Medical ISBN : 9789240031593
Consolidated guidelines on HIV prevention, testing, treatment, service delivery and monitoring by World Health Organization Pdf
These consolidated guidelines on HIV prevention, testing, treatment, service delivery and monitoring bring together existing and new clinical and programmatic recommendations across different ages, populations and settings, bringing together all relevant WHO guidance on HIV produced since 2016. It serves as an update to the previous edition of the consolidated guidelines on HIV. These guidelines continue to be structured along the continuum of HIV care. Information on new combination prevention approaches, HIV testing, ARV regimens and treatment monitoring are included. There is a new chapter on advanced HIV disease that integrates updated guidance on the management of important HIV comorbidities, including cryptococcal disease, histoplasmosis and tuberculosis. The chapter on general HIV care, contains a new section on palliative care and pain management, and up to date information on treatment of several neglected tropical diseases, such as visceral leishmaniasis and Buruli ulcer. New recommendations for screening and treating of cervical pre-cancer lesions in women living with HIV are also addressed in this chapter. Guidance on service delivery was expanded to help the implementation and strengthening the HIV care cascade. Importantly, this guidance emphasizes the need for differentiated approaches to care for people who are established on ART, such as reduced frequency of clinic visits, use of multi-month drug dispensing and implementation of community ART distribution. The adoption of these efficiencies is essential to improve the quality of care of people receiving treatment and reduce the burden on health facilities, particularly in resource limited settings.
Optimization of Behavioral, Biobehavioral, and Biomedical Interventions by Linda M. Collins Pdf
This book presents a framework for development, optimization, and evaluation of behavioral, biobehavioral, and biomedical interventions. Behavioral, biobehavioral, and biomedical interventions are programs with the objective of improving and maintaining human health and well-being, broadly defined, in individuals, families, schools, organizations, or communities. These interventions may be aimed at, for example, preventing or treating disease, promoting physical and mental health, preventing violence, or improving academic achievement. This volume introduces the multiphase optimization strategy (MOST), pioneered at The Methodology Center at the Pennsylvania State University, as an alternative to the classical approach of relying solely on the randomized controlled trial (RCT). MOST borrows heavily from perspectives taken and approaches used in engineering, and also integrates concepts from statistics and behavioral science, including the RCT. As described in detail in this book, MOST consists of three phases: preparation, in which the conceptual model underlying the intervention is articulated; optimization, in which experimentation is used to gather the information necessary to identify the optimized intervention; and evaluation, in which the optimized intervention is evaluated in a standard RCT. Through numerous examples, the book demonstrates that MOST can be used to develop interventions that are more effective, efficient, economical, and scalable. Optimization of Behavioral, Biobehavioral, and Biomedical Interventions: The Multiphase Optimization Strategy is the first book to present a comprehensive introduction to MOST. It will be an essential resource for behavioral, biobehavioral, and biomedical scientists; statisticians, biostatisticians, and analysts working in epidemiology and public health; and graduate-level courses in development and evaluation of interventions.
Author : World Health Organization Publisher : World Health Organization Page : 24 pages File Size : 45,5 Mb Release : 2022-07-11 Category : Medical ISBN : 9789240052871
Virtual workshop on postnatal prophylaxis to reach elimination of HIV vertical transmission by World Health Organization Pdf
Despite decades of progress in reducing the rates of vertical transmission, children continue to acquire HIV. Options for more effective regimens to prevent HIV infection among infants have been considered and a number of innovative strategies hold promise to substantially transform postnatal prophylaxis so that elimination of HIV vertical transmission can be achieved. This meeting report synthetizes the outcomes of a workshop held in 2021 by IMPAACT and WHO to achieve consensus on the approach to investigating innovative strategies to prevent HIV vertical transmission perinatally and in the postnatal period and establish the next steps for implementing such studies.
Institute for Operations Research and the Management Sciences. National Meeting
Author : Institute for Operations Research and the Management Sciences. National Meeting Publisher : Unknown Page : 480 pages File Size : 43,6 Mb Release : 2008 Category : Industrial management ISBN : CORNELL:31924083389233
Institute of Medicine,Board on Health Care Services,Committee on Standards for Systematic Reviews of Comparative Effectiveness Research
Author : Institute of Medicine,Board on Health Care Services,Committee on Standards for Systematic Reviews of Comparative Effectiveness Research Publisher : National Academies Press Page : 267 pages File Size : 54,6 Mb Release : 2011-06-20 Category : Medical ISBN : 9780309216715
Finding What Works in Health Care by Institute of Medicine,Board on Health Care Services,Committee on Standards for Systematic Reviews of Comparative Effectiveness Research Pdf
Healthcare decision makers in search of reliable information that compares health interventions increasingly turn to systematic reviews for the best summary of the evidence. Systematic reviews identify, select, assess, and synthesize the findings of similar but separate studies, and can help clarify what is known and not known about the potential benefits and harms of drugs, devices, and other healthcare services. Systematic reviews can be helpful for clinicians who want to integrate research findings into their daily practices, for patients to make well-informed choices about their own care, for professional medical societies and other organizations that develop clinical practice guidelines. Too often systematic reviews are of uncertain or poor quality. There are no universally accepted standards for developing systematic reviews leading to variability in how conflicts of interest and biases are handled, how evidence is appraised, and the overall scientific rigor of the process. In Finding What Works in Health Care the Institute of Medicine (IOM) recommends 21 standards for developing high-quality systematic reviews of comparative effectiveness research. The standards address the entire systematic review process from the initial steps of formulating the topic and building the review team to producing a detailed final report that synthesizes what the evidence shows and where knowledge gaps remain. Finding What Works in Health Care also proposes a framework for improving the quality of the science underpinning systematic reviews. This book will serve as a vital resource for both sponsors and producers of systematic reviews of comparative effectiveness research.
