3d Printable Gel Inks For Tissue Engineering

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3D printable Gel-inks for Tissue Engineering

Author : Anuj Kumar,Stefan Ioan Voicu,Vijay Kumar Thakur
Publisher : Springer Nature
Page : 395 pages
File Size : 48,8 Mb
Release : 2021-09-11
Category : Technology & Engineering
ISBN : 9789811646676

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3D printable Gel-inks for Tissue Engineering by Anuj Kumar,Stefan Ioan Voicu,Vijay Kumar Thakur Pdf

This book provides the necessary fundamentals and background for researchers and research professionals working in the field of 3D bioprinting in tissue engineering. In 3D bioprinting, design and development of the biomaterial-inks/bio-inks is a major challenge in providing 3D microenvironments specific to anatomical and architectural demands of native tissues. The focal point of this book is to provide the basic chemistry of biomaterials, updates on current processing, developments, and challenges, and recent advancements in tissue-specific 3D printing/bioprinting. This book is will serve as a go-to reference on bioprinting and is ideal for students, researchers and professionals, working academia, government, the medical industry, and healthcare.

3D Printing for Tissue Engineering and Regenerative Medicine

Author : Murat Guvendiren ,Vahid Serpooshan
Publisher : MDPI
Page : 166 pages
File Size : 50,8 Mb
Release : 2020-12-02
Category : Technology & Engineering
ISBN : 9783039361120

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3D Printing for Tissue Engineering and Regenerative Medicine by Murat Guvendiren ,Vahid Serpooshan Pdf

Three-dimensional (3D) printing enables the fabrication of tissue-engineered constructs and devices from a patient’s own medical data, leading to the creation of anatomically matched and patient-specific constructs. There is a growing interest in applying 3D printing technologies in the fields of tissue engineering and regenerative medicine. The main printing methods include extrusion-based, vat photopolymerization, droplet-based, and powder-based printing. A variety of materials have been used for printing, from metal alloys and ceramics to polymers and elastomers as well as from hydrogels to extracellular matrix proteins. More recently, bioprinting, a subcategory of 3D printing, has enabled the precise assembly of cell-laden biomaterials (i.e., bioinks) for the construction of complex 3D functional living tissues or artificial organs. In this Special Issue, we aim to capture state-of-the-art research papers and the most current review papers focusing on 3D printing for tissue engineering and regenerative medicine. In particular, we seek novel studies on the development of 3D printing and bioprinting approaches, developing printable materials (inks and bioinks), and utilizing 3D-printed scaffolds for tissue engineering and regenerative medicine applications. These applications are not limited to but include scaffolds for in vivo tissue regeneration and tissue analogues for in vitro disease modeling and/or drug screening.

Advanced 3D-Printed Systems and Nanosystems for Drug Delivery and Tissue Engineering

Author : Lisa C. du Toit,Pradeep Kumar,Yahya E. Choonara,Viness Pillay
Publisher : Elsevier
Page : 318 pages
File Size : 50,8 Mb
Release : 2020-03-08
Category : Technology & Engineering
ISBN : 9780128184721

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Advanced 3D-Printed Systems and Nanosystems for Drug Delivery and Tissue Engineering by Lisa C. du Toit,Pradeep Kumar,Yahya E. Choonara,Viness Pillay Pdf

Advanced 3D-Printed Systems and Nanosystems for Drug Delivery and Tissue Engineering explores the intricacies of nanostructures and 3D printed systems in terms of their design as drug delivery or tissue engineering devices, their further evaluations and diverse applications. The book highlights the most recent advances in both nanosystems and 3D-printed systems for both drug delivery and tissue engineering applications. It discusses the convergence of biofabrication with nanotechnology, constructing a directional customizable biomaterial arrangement for promoting tissue regeneration, combined with the potential for controlled bioactive delivery. These discussions provide a new viewpoint for both biomaterials scientists and pharmaceutical scientists. Shows how nanotechnology and 3D printing are being used to create systems which are intelligent, biomimetic and customizable to the patient Explores the current generation of nanostructured 3D printed medical devices Assesses the major challenges of using 3D printed nanosystems for the manufacture of new pharmaceuticals

3D Bioprinting in Medicine

Author : Murat Guvendiren
Publisher : Springer
Page : 209 pages
File Size : 54,5 Mb
Release : 2019-08-02
Category : Medical
ISBN : 9783030239060

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3D Bioprinting in Medicine by Murat Guvendiren Pdf

This book provides current and emerging developments in bioprinting with respect to bioprinting technologies, bioinks, applications, and regulatory pathways. Topics covered include 3D bioprinting technologies, materials such as bioinks and bioink design, applications of bioprinting complex tissues, tissue and disease models, vasculature, and musculoskeletal tissue. The final chapter is devoted to clinical applications of bioprinting, including the safety, ethical, and regulatory aspects. This book serves as a go-to reference on bioprinting and is ideal for students, researchers and professionals, including those in academia, government, the medical industry, and healthcare.

3D Printing in Medicine and Surgery

Author : Daniel J. Thomas,Deepti Singh
Publisher : Woodhead Publishing
Page : 306 pages
File Size : 46,6 Mb
Release : 2020-08-14
Category : Technology & Engineering
ISBN : 9780081025437

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3D Printing in Medicine and Surgery by Daniel J. Thomas,Deepti Singh Pdf

3D Printing in Medicine and Surgery: Applications in Healthcare is an advanced book on surgical and enhanced medical applications that can be achieved with 3D printing. It is an essential handbook for medical practitioners, giving access to a range of practical methods, while also focusing on applied knowledge. This comprehensive resource features practical experiments and processes for preparing 3D printable materials. Early chapters cover foundational knowledge and background reading, while later chapters discuss and review the current technologies used to engineer specific tissue types, experiments and methods, medical approaches and the challenges that lie ahead for future research. The book is an indispensable reference guide to the various methods used by current medical practitioners working at the forefront of 3D printing applications in medicine. Provides a detailed introduction and narrative on how 3-D printing can be used towards developing future medicine-based therapies Covers up-to-date methods across a range of application areas for the first time in book form Presents the only book on all current areas of 3D printing in medicine that is catered to a medical rather than engineering audience

Biocomposite Inks for 3D Printing

Author : Gary Chinga Carrasco
Publisher : Mdpi AG
Page : 214 pages
File Size : 55,8 Mb
Release : 2021-09-30
Category : Science
ISBN : 3036517383

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Biocomposite Inks for 3D Printing by Gary Chinga Carrasco Pdf

Three-dimensional (3D) printing has evolved massively during the last years. The 3D printing technologies offer various advantages, including: i) tailor-made design, ii) rapid prototyping, and iii) manufacturing of complex structures. Importantly, 3D printing is currently finding its potential in tissue engineering, wound dressings, tissue models for drug testing, prosthesis, and biosensors, to name a few. One important factor is the optimized composition of inks that can facilitate the deposition of cells, fabrication of vascularized tissue and the structuring of complex constructs that are similar to functional organs. Biocomposite inks can include synthetic and natural polymers, such as poly (ε-caprolactone), polylactic acid, collagen, hyaluronic acid, alginate, nanocellulose, and may be complemented with cross-linkers to stabilize the constructs and with bioactive molecules to add functionality. Inks that contain living cells are referred to as bioinks and the process as 3D bioprinting. Some of the key aspects of the formulation of bioinks are, e.g., the tailoring of mechanical properties, biocompatibility and the rheological behavior of the ink which may affect the cell viability, proliferation, and cell differentiation.

3D Printing in Medicine

Author : Deepak M. Kalaskar
Publisher : Woodhead Publishing
Page : 424 pages
File Size : 42,8 Mb
Release : 2022-10-18
Category : Technology & Engineering
ISBN : 9780323902205

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3D Printing in Medicine by Deepak M. Kalaskar Pdf

3D Printing in Medicine, Second Edition examines the rapidly growing market of 3D-printed biomaterials and their clinical applications. With a particular focus on both commercial and premarket tools, the book looks at their applications within medicine and the future outlook for the field. The chapters are written by field experts actively engaged in educational and research activities at the top universities in the world. The earlier chapters cover the fundamentals of 3D printing, including topics such as materials and hardware. The later chapters go on to cover innovative applications within medicine such as computational analysis of 3D printed constructs, personalized 3D printing - including 3D cell and organ printing and the role of AI - with a subsequent look at the applications of high-resolution printing, 3D printing in diagnostics, drug development, 4D printing, and much more. This updated new edition features completely revised content, with additional new chapters covering organs-on-chips, bioprinting regulations and standards, intellectual properties, and socio-ethical implications of organs-on-demand. Reviews a broad range of biomedical applications of 3D printing biomaterials and technologies Provides an interdisciplinary look at 3D printing in medicine, bridging the gap between engineering and clinical fields Includes completely updated content with additional new chapters, covering topics such as organs-on-chips, bioprinting regulations, intellectual properties, medical standards in 3D printing, and more

Injectable Hydrogels for 3D Bioprinting

Author : Insup Noh,Xiumei Wang,Sandra van Vlierberghe
Publisher : Royal Society of Chemistry
Page : 505 pages
File Size : 43,7 Mb
Release : 2021-07-30
Category : Technology & Engineering
ISBN : 9781788018838

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Injectable Hydrogels for 3D Bioprinting by Insup Noh,Xiumei Wang,Sandra van Vlierberghe Pdf

Hydrogels represent one of the cornerstones in tissue engineering and regenerative medicine, due to their biocompatibility and physiologically relevant properties. These inherent characteristics mean that they can be widely exploited as bioinks in 3D bioprinting for tissue engineering applications as well as injectable gels for cell therapy and drug delivery purposes. The research in these fields is booming and this book provides the reader with a terrific introduction to the burgeoning field of injectable hydrogel design, bioprinting and tissue engineering. Edited by three leaders in the field, users of this book will learn about different classes of hydrogels, properties and synthesis strategies to produce bioinks. A section devoted to the key processing and design challenges at the hydrogel/3D bioprinting/tissue interface is also covered. The final section of the book closes with pertinent clinical applications. Tightly edited, the reader will find this book to be a coherent resource to learn from. It will appeal to those working across biomaterials science, chemical and biomedical engineering, tissue engineering and regenerative medicine.

Cell Assembly with 3D Bioprinting

Author : Yong He,Qing Gao,Yifei Jin
Publisher : John Wiley & Sons
Page : 370 pages
File Size : 43,9 Mb
Release : 2022-03-14
Category : Technology & Engineering
ISBN : 9783527347964

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Cell Assembly with 3D Bioprinting by Yong He,Qing Gao,Yifei Jin Pdf

Provides an up-to-date outline of cell assembly methods and applications of 3D bioprinting Cell Assembly with 3D Bioprinting provides an accesible overview of the layer-by-layer manufacturing of living structures using biomaterials. Focusing on technical implemention in medical and bioengineering applications, this practical guide summarize each key aspect of the 3D bioprinting process. Contributions from a team of leading researchers describe bioink preparation, printing method selection, experimental protocols, integration with specific applications, and more. Detailed, highly illustrated chapters cover different bioprinting approaches and their applications, including coaxial bioprinting, digital light projection, direct ink writing, liquid support bath-assisted 3D printing, and microgel-, microfiber-, and microfluidics-based biofabrication. The book includes practical examples of 3D bioprinting, a protocol for typical 3D bioprinting, and relevant experimental data drawn from recent research. * Highlights the interdisciplinary nature of 3D bioprinting and its applications in biology, medicine, and pharmaceutical science * Summarizes a variety of commonly used 3D bioprinting methods * Describes the design and preparation of various types of bioinks * Discusses applications of 3D bioprinting such as organ development, toxicological research, clinical transplantation, and tissue repair Covering a wide range of topics, Cell Assembly with 3D Bioprinting is essential reading for advanced students, academic researchers, and industry professionals in fields including biomedicine, tissue engineering, bioengineering, drug development, pharmacology, bioglogical screening, and mechanical engineering.

3D Bioprinting for Reconstructive Surgery

Author : Daniel Thomas,Zita M. Jessop,Iain S. Whitaker
Publisher : Woodhead Publishing
Page : 450 pages
File Size : 55,7 Mb
Release : 2017-11-14
Category : Technology & Engineering
ISBN : 9780081012161

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3D Bioprinting for Reconstructive Surgery by Daniel Thomas,Zita M. Jessop,Iain S. Whitaker Pdf

3D Bioprinting for Reconstructive Surgery: Techniques and Applications examines the combined use of materials, procedures and tools necessary for creating structural tissue constructs for reconstructive purposes. Offering a broad analysis of the field, the first set of chapters review the range of biomaterials which can be used to create 3D-printed tissue constructs. Part Two looks at the techniques needed to prepare biomaterials and biological materials for 3D printing, while the final set of chapters examines application-specific examples of tissues formed from 3D printed biomaterials. 3D printing of biomaterials for tissue engineering applications is becoming increasingly popular due to its ability to offer unique, patient-specific parts—on demand—at a relatively low cost. This book is a valuable resource for biomaterials scientists, biomedical engineers, practitioners and students wishing to broaden their knowledge in the allied field. Discusses new possibilities in tissue engineering with 3D printing Presents a comprehensive coverage of the materials, techniques and tools needed for producing bioprinted tissues Reviews emerging technologies in addition to commercial techniques

3D Bioprinting in Regenerative Engineering

Author : Ali Khademhosseini,Gulden Camci-Unal
Publisher : CRC Press
Page : 300 pages
File Size : 49,5 Mb
Release : 2018-04-17
Category : Technology & Engineering
ISBN : 9781315280479

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3D Bioprinting in Regenerative Engineering by Ali Khademhosseini,Gulden Camci-Unal Pdf

Regenerative engineering is the convergence of developmental biology, stem cell science and engineering, materials science, and clinical translation to provide tissue patches or constructs for diseased or damaged organs. Various methods have been introduced to create tissue constructs with clinically relevant dimensions. Among such methods, 3D bioprinting provides the versatility, speed and control over location and dimensions of the deposited structures. Three-dimensional bioprinting has leveraged the momentum in printing and tissue engineering technologies and has emerged as a versatile method of fabricating tissue blocks and patches. The flexibility of the system lies in the fact that numerous biomaterials encapsulated with living cells can be printed. This book contains an extensive collection of papers by world-renowned experts in 3D bioprinting. In addition to providing entry-level knowledge about bioprinting, the authors delve into the latest advances in this technology. Furthermore, details are included about the different technologies used in bioprinting. In addition to the equipment for bioprinting, the book also describes the different biomaterials and cells used in these approaches. This text: Presents the principles and applications of bioprinting Discusses bioinks for 3D printing Explores applications of extrusion bioprinting, including past, present, and future challenges Includes discussion on 4D Bioprinting in terms of mechanisms and applications

3D Bioprinting

Author : Dong-Woo Cho,Byoung Soo Kim,Jinah Jang,Ge Gao,Wonil Han,Narendra K. Singh
Publisher : Springer Nature
Page : 124 pages
File Size : 49,6 Mb
Release : 2019-12-04
Category : Medical
ISBN : 9783030322229

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3D Bioprinting by Dong-Woo Cho,Byoung Soo Kim,Jinah Jang,Ge Gao,Wonil Han,Narendra K. Singh Pdf

This text advances fundamental knowledge in modeling in vitro tissues/organs as an alternative to 2D cell culture and animal testing. Prior to engineering in vitro tissues/organs,the descriptions of prerequisites (from pre-processing to post-processing) in modeling in vitro tissues/organs are discussed. The most prevalent technologies that have been widely used for establishing the in vitro tissue/organ models are also described, including transwell, cell spheroids/sheets, organoids, and microfluidic-based chips. In particular, the authors focus on 3D bioprinting in vitro tissue/organ models using tissue-specific bioinks. Several representative bioprinting methods and conventional bioinks are introduced. As a bioink source, decellularized extracellular matrix (dECM) are importantly covered, including decellularization methods, evaluation methods for demonstrating successful decellularization, and material safety. Taken together, the authors delineate various application examples of 3D bioprinted in vitro tissue/organ models especially using dECM bioinks.

Applications of 3D printing in Biomedical Engineering

Author : Neeta Raj Sharma,Karupppasamy Subburaj,Kamalpreet Sandhu,Vivek Sharma
Publisher : Springer Nature
Page : 216 pages
File Size : 49,5 Mb
Release : 2021-04-21
Category : Science
ISBN : 9789813368880

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Applications of 3D printing in Biomedical Engineering by Neeta Raj Sharma,Karupppasamy Subburaj,Kamalpreet Sandhu,Vivek Sharma Pdf

This book focuses on applications of three-dimensional (3D) printing in healthcare. It first describes a range of biomaterials, including their physicochemical and biological properties. It then reviews the current state of the art in bioprinting techniques and the potential application of bioprinting, computer-aided additive manufacturing of cells, tissues, and scaffolds to create organs in regenerative medicine. Further, it discusses the orthopedic applications of 3D printing in the design and fabrication of dental implants, and the use of 3D bioprinting in oral and maxillofacial surgery and in tissue and organ engineering. Lastly, the book examines the 3D printing technologies that are used for the fabrication of the drug delivery system. It also explores the current challenges and the future of 3D bioprinting in medical sciences, as well as the market demand.

Biofabrication and 3D Tissue Modeling

Author : Dong-Woo Cho
Publisher : Royal Society of Chemistry
Page : 369 pages
File Size : 55,5 Mb
Release : 2019-01-02
Category : Technology & Engineering
ISBN : 9781788011983

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Biofabrication and 3D Tissue Modeling by Dong-Woo Cho Pdf

3D tissue modelling is an emerging field used for the investigation of disease mechanisms and drug development. The two key drivers of this upsurge in research lie in its potential to offer a way to reduce animal testing with respect to biotoxicity analysis, preferably on physiology recapitulated human tissues and, additionally, it provides an alternative approach to regenerative medicine. Integrating physics, chemistry, materials science, and stem cell and biomedical engineering, this book provides a complete foundation to this exciting, and interdisciplinary field. Beginning with the basic principles of 3D tissue modelling, the reader will find expert reviews on key fabrication technologies and processes, including microfluidics, microfabrication technology such as 3D bioprinting, and programming approaches to emulating human tissue complexity. The next stage introduces the reader to a range of materials used for 3D tissue modelling, from synthetic to natural materials, as well as the emerging field of tissue derived decellularized extracellular matrix (dECM). A whole host of critical applications are covered, with several chapters dedicated to hard and soft tissues, as well as focused reviews on the respiratory and central nervous system. Finally, the development of in vitro tissue models to screen drugs and study progression and etiologies of diseases, with particular attention paid to cancer, can be found.

3D Bioprinting and Nanotechnology in Tissue Engineering and Regenerative Medicine

Author : Lijie Grace Zhang,Kam Leong,John P. Fisher
Publisher : Academic Press
Page : 563 pages
File Size : 45,8 Mb
Release : 2022-02-18
Category : Technology & Engineering
ISBN : 9780128245538

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3D Bioprinting and Nanotechnology in Tissue Engineering and Regenerative Medicine by Lijie Grace Zhang,Kam Leong,John P. Fisher Pdf

3D Bioprinting and Nanotechnology in Tissue Engineering and Regenerative Medicine, Second Edition provides an in-depth introduction to bioprinting and nanotechnology and their industrial applications. Sections cover 4D Printing Smart Multi-responsive Structure, Cells for Bioprinting, 4D Printing Biomaterials, 3D/4D printing functional biomedical devices, 3D Printing for Cardiac and Heart Regeneration, Integrating 3D printing with Ultrasound for Musculoskeletal Regeneration, 3D Printing for Liver Regeneration, 3D Printing for Cancer Studies, 4D Printing Soft Bio-robots, Clinical Translation and Future Directions. The book's team of expert contributors have pooled their expertise in order to provide a summary of the suitability, sustainability and limitations of each technique for each specific application. The increasing availability and decreasing costs of nanotechnologies and 3D printing technologies are driving their use to meet medical needs. This book provides an overview of these technologies and their integration. Includes clinical applications, regulatory hurdles, and a risk-benefit analysis of each technology Assists readers in selecting the best materials and how to identify the right parameters for printing Includes the advantages of integrating 3D printing and nanotechnology in order to improve the safety of nano-scale materials for biomedical applications