A Concise Review Of Molecular Pathology Of Breast Cancer

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A Concise Review of Molecular Pathology of Breast Cancer

Mehmet Gunduz
A Concise Review of Molecular Pathology of Breast Cancer Book PDF

Author : Mehmet Gunduz
Publisher : BoD – Books on Demand
Page : 236 pages
File Size : 42,9 Mb
Release : 2015-03-25
Category : Medical
ISBN : 9789535120308

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A Concise Review of Molecular Pathology of Breast Cancer by Mehmet Gunduz Pdf

Cancer is one of the leading causes of death in most countries and its consequences result in huge economic, social and psychological burden. Breast cancer is the most frequently diagnosed cancer type and the leading cause of cancer death among females. In this book, we discussed gene expression and DNA abnormalities including methylation in breast cancer. A recent important topic, roles of miRNAs and their potential use in cancer therapy have been discussed in this cancer type as well. Bioinformatics is very important part of recent human genome developments and data mining and thus this topic has also been added for the readers. It is hoped that this book will contribute to development of novel diagnostic as well as therapeutic approaches, which lead to cure of breast cancer.

Precision Molecular Pathology of Breast Cancer

Ashraf Khan,Ian O. Ellis,Andrew M. Hanby,Ediz F. Cosar,Emad A. Rakha,Dina Kandil
Precision Molecular Pathology of Breast Cancer Book PDF

Author : Ashraf Khan,Ian O. Ellis,Andrew M. Hanby,Ediz F. Cosar,Emad A. Rakha,Dina Kandil
Publisher : Springer
Page : 338 pages
File Size : 48,8 Mb
Release : 2015-08-12
Category : Medical
ISBN : 9781493928866

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Precision Molecular Pathology of Breast Cancer by Ashraf Khan,Ian O. Ellis,Andrew M. Hanby,Ediz F. Cosar,Emad A. Rakha,Dina Kandil Pdf

This volume provides a comprehensive review of the molecular mechanisms involved in precancerous lesions and benign and malignant breast tumors. Given the complex molecular pathways in breast cancer biology, the book simplifies these complex mechanisms and highlights the practical issues important for daily practice. Sections are structured to review breast carcinogenesis and the role of familial predisposition and stem cells in initiation and progression of breast cancer. In-depth chapters present morphologic and molecular correlations in precancerous and malignant breast lesions, while outlining highly practical issues that are in practice today in breast pathology, such as evaluation of estrogen, progesterone receptors, and HER-2. Written by experts in the field, Precision Molecular Pathology of Breast Cancer is a valuable resource that covers the current practice of breast pathology and looks into the future with an emphasis on the molecular basis of breast cancer.

Basic Concepts of Molecular Pathology

Philip T. Cagle,Timothy Craig Allen
Basic Concepts of Molecular Pathology Book PDF

Author : Philip T. Cagle,Timothy Craig Allen
Publisher : Springer Science & Business Media
Page : 195 pages
File Size : 46,7 Mb
Release : 2009-06-10
Category : Medical
ISBN : 9780387896267

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Basic Concepts of Molecular Pathology by Philip T. Cagle,Timothy Craig Allen Pdf

Over the past two decades there has been an explosion in knowledge about the molecular pathology of human diseases which accelerated with the sequencing of the human genome in 2003. Molecular diagnostics and molecular targeted therapy have contributed to the current concept of personalized patient care that is now routine in many medical centers. As a result, general and subspecialty pathologists, clinical practitioners of all types and radiologists must now have an understanding of the basic concepts of molecular pathology and their role in new diagnostic and therapeutic applications to patient care. The Molecular Pathology Library series was created to bridge the gap between traditional basic science textbooks in molecular biology and traditional medical textbooks for organ-specific diseases. Basic Concepts of Molecular Pathology is designed as a stand-alone book to provide the pathologist, clinician or radiologist with a concise review of the essential terminology, concepts and tools of molecular biology that are applied to the understanding, diagnosis and treatment of human diseases in the age of personalized medicine. Those medical practitioners, residents, fellows and students who need to refer to the terminology and concepts of molecular pathology in their patient care will find the Basic Concepts of Molecular Pathology to be a succinct, portable, user-friendly aid in their practice and studies. The service-based physician will find this handy reference to be valuable at the laboratory benchside, at the patient bedside, at multidisciplinary patient care conferences or as a review for examinations.

Molecular Surgical Pathology

Liang Cheng,John N. Eble
Molecular Surgical Pathology Book PDF

Author : Liang Cheng,John N. Eble
Publisher : Springer Science & Business Media
Page : 442 pages
File Size : 53,6 Mb
Release : 2012-11-15
Category : Medical
ISBN : 9781461449003

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Molecular Surgical Pathology by Liang Cheng,John N. Eble Pdf

Molecular Surgical Pathology provides a concise review of recent advancement of molecular pathology in each organ system. The text is intended as a “first knowledge base” in the rapidly evolving field of molecular pathology and is organized in a user friendly outline format. Each chapter is organ-based and covers important aspects of molecular pathology and its impact on our daily practice of surgical pathology. The topics presented herein constitute the fundamentals and core base of knowledge required for the daily practice of surgical pathology. This book focuses on the practical utilities of molecular techniques and molecular biomarkers in daily practice of surgical pathology. The emphasis is on the impact of molecular pathology for tumor classification, diagnosis and differential diagnosis as well as its implications for patient management and personalized care. Numerous tables, diagrams and color illustrations are included throughout. Molecular Surgical Pathology will prove a very useful resource for pathologists in training who are preparing for the Board and in-service examination. It will also be a unique and invaluable resource for medical oncologists, physicians, other medical professionals and basic research scientists with interest in molecular pathology of human cancers.

Essential Concepts in Molecular Pathology

William B. Coleman,Gregory J. Tsongalis
Essential Concepts in Molecular Pathology Book PDF

Author : William B. Coleman,Gregory J. Tsongalis
Publisher : Academic Press
Page : 634 pages
File Size : 40,9 Mb
Release : 2019-11-23
Category : Medical
ISBN : 9780128132586

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Essential Concepts in Molecular Pathology by William B. Coleman,Gregory J. Tsongalis Pdf

Essential Concepts in Molecular Pathology, Second Edition, offers an introduction to molecular genetics and the "molecular" aspects of human disease. The book illustrates how pathologists harness their understanding of these entities to develop new diagnostics and treatments for various human diseases. This new edition offers pathology, genetics residents, and molecular pathology fellows an advanced understanding of the molecular mechanisms of disease that goes beyond what they learned in medical and graduate school. By bridging molecular concepts of pathogenesis to the clinical expression of disease in cell, tissue and organ, this fully updated, introductory reference provides the background necessary for an understanding of today’s advances in pathology and medicine. Explains the practice of "molecular medicine" and the translational aspects of molecular pathology, including molecular diagnostics, molecular assessment and personalized medicine Orients non-pathologists on what pathologists look for and how they interpret their observational findings based on histopathology Provides the reader with what is missing from most targeted introductions to pathology—the cell biology behind pathophysiology

Pathology and Epidemiology of Cancer

Massimo Loda,Lorelei A. Mucci,Megan L. Mittelstadt,Mieke Van Hemelrijck,Maura Bríd Cotter
Pathology and Epidemiology of Cancer Book PDF

Author : Massimo Loda,Lorelei A. Mucci,Megan L. Mittelstadt,Mieke Van Hemelrijck,Maura Bríd Cotter
Publisher : Springer
Page : 670 pages
File Size : 48,5 Mb
Release : 2016-09-01
Category : Medical
ISBN : 9783319351537

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Pathology and Epidemiology of Cancer by Massimo Loda,Lorelei A. Mucci,Megan L. Mittelstadt,Mieke Van Hemelrijck,Maura Bríd Cotter Pdf

This book integrates the disciplines of cancer pathology and epidemiology to provide a synergistic and complementary approach to understanding the molecular mechanisms of cancer. This book provides relevant information on the diagnostic, prognostic and predictive molecular pathology of cancer. Epidemiological studies, including descriptive epidemiology, risk factors and molecular mechanisms of disease inform on the etiology and progression of cancer. The text concentrates on major cancers that are currently prevalent and those for which substantial molecular, pathological and epidemiological data is available. Each section is designed to provide an overview of that cancer type in terms of basic biology, review the current epidemiological data surrounding that cancer type and provide information on common practices and challenges related to the molecular pathology of that cancer type. Several relevant techniques in molecular pathology, which facilitate diagnosis and treatment are also explored. Pathology and Epidemiology of Cancer provides a succinct and comprehensive overview of multiple cancer types to guide clinicians during patient care and to guide scientists for innovations in research. It represents an integral resource for pathologists, epidemiologists, medical students as well as translational, basic and clinical science researchers who are all working to progress the field of cancer in terms of diagnosis, treatment and prevention.

Molecular Pathology

William B. Coleman,Gregory J. Tsongalis
Molecular Pathology Book PDF

Author : William B. Coleman,Gregory J. Tsongalis
Publisher : Academic Press
Page : 802 pages
File Size : 52,6 Mb
Release : 2017-11-09
Category : Medical
ISBN : 9780128027875

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Molecular Pathology by William B. Coleman,Gregory J. Tsongalis Pdf

As the molecular basis of human disease becomes better characterized, and the implications for understanding the molecular basis of disease becomes realized through improved diagnostics and treatment, Molecular Pathology, Second Edition stands out as the most comprehensive textbook where molecular mechanisms represent the focus. It is uniquely concerned with the molecular basis of major human diseases and disease processes, presented in the context of traditional pathology, with implications for translational molecular medicine. The Second Edition of Molecular Pathology has been thoroughly updated to reflect seven years of exponential changes in the fields of genetics, molecular, and cell biology which molecular pathology translates in the practice of molecular medicine. The textbook is intended to serve as a multi-use textbook that would be appropriate as a classroom teaching tool for biomedical graduate students, medical students, allied health students, and others (such as advanced undergraduates). Further, this textbook will be valuable for pathology residents and other postdoctoral fellows that desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. In addition, this textbook is useful as a reference book for practicing basic scientists and physician scientists that perform disease-related basic science and translational research, who require a ready information resource on the molecular basis of various human diseases and disease states. Explores the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease Explains the practice of “molecular medicine and the translational aspects of molecular pathology Teaches from the perspective of “integrative systems biology Enhanced digital version included with purchase

Treatment Landscape of Targeted Therapies in Oncology

Pawan Kumar Maurya,Vikas Saini
Treatment Landscape of Targeted Therapies in Oncology Book PDF

Author : Pawan Kumar Maurya,Vikas Saini
Publisher : Elsevier
Page : 271 pages
File Size : 51,7 Mb
Release : 2023-07-29
Category : Science
ISBN : 9780443160356

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Treatment Landscape of Targeted Therapies in Oncology by Pawan Kumar Maurya,Vikas Saini Pdf

Treatment Landscape of Targeted Therapies in Oncology: Challenges and Opportunities provides up-to-date knowledge on antitumor-targeted therapies and immunotherapy. The book's chapters are written by researchers dynamically working/focusing on cancer treatment. The content is designed to help those who are new to the field (beginners) and various specialized scientists and researchers involved in cancer research. For decades, the hallmark of cancer treatment has been conventional chemotherapy. But with the rapid increase in our understanding of the immune system, more and more small molecules, peptides, recombinant antibodies, vaccines and cellular therapeutic modalities are being applied to manipulate the immune response for cancer treatment. Covers basic concepts and updated knowledge of the latest anticancer drugs Brings comprehensive understanding of the treatment of cancer in context of immunotherapy and targeted therapy Introduces the latest drugs and advancements in the treatment of cancer Includes detailed diagrams to give insight to the mechanisms of action

Advanced Nanoformulations

Md Saquib Hasnain,Amit Kumar Nayak,Tejraj M. Aminabhavi
Advanced Nanoformulations Book PDF

Author : Md Saquib Hasnain,Amit Kumar Nayak,Tejraj M. Aminabhavi
Publisher : Academic Press
Page : 873 pages
File Size : 44,5 Mb
Release : 2023-03-24
Category : Medical
ISBN : 9780323885799

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Advanced Nanoformulations by Md Saquib Hasnain,Amit Kumar Nayak,Tejraj M. Aminabhavi Pdf

Advanced Nanoformulations: Theranostic Nanosystems, Volume Three examines the applications of nanotherapeutic systems and nanodiagnostics in relation to polymeric nanosystems. In the last decade, numerous biopolymers have been utilized to prepare polymeric nanosystems for therapeutic applications. These biopolymers include polylactic acid, polylactide-co-glycolide, polycaprolactone, acrylic polymers, cellulose and cellulose derivatives, alginates, chitosan, gellan gum, gelatin, albumin, chontroitin sulfate, hyaluronic acid, guar gum, gum Arabic, gum tragacanth, xanthan gum, and starches. Besides these biopolymers, grafted polymers are also being used as advanced polymeric materials to prepare many theranostic nanocarriers and nanoformulations. This book explores the array of polymeric nanosystems to understand therapeutic potentials. It will be useful to pharmaceutical scientists, including industrial pharmacists and analytical scientists, health care professionals, and regulatory scientists actively involved in the pharmaceutical product and process development of tailor-made polysaccharides in drug delivery applications. Contains in-depth discussions of the advanced formulations using nanosystems including high-quality graphics, flowcharts, and graphs for enhanced understanding Reviews the literature on advanced formulations while also suggesting new avenues Includes contributions in all areas of advanced formulations, providing a thorough and interdisciplinary work

Applications of Bioinformatics in Rice Research

Manoj Kumar Gupta,Lambodar Behera
Applications of Bioinformatics in Rice Research Book PDF

Author : Manoj Kumar Gupta,Lambodar Behera
Publisher : Springer Nature
Page : 363 pages
File Size : 43,5 Mb
Release : 2021-09-24
Category : Science
ISBN : 9789811639975

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Applications of Bioinformatics in Rice Research by Manoj Kumar Gupta,Lambodar Behera Pdf

This book summarizes the advanced computational methods for mapping high-density linkages and quantitative trait loci in the rice genome. It also discusses the tools for analyzing metabolomics, identifying complex polyploidy genomes, and decoding the extrachromosomal genome in rice. Further, the book highlights the application of CRISPR-Cas technology and methods for understanding the evolutionary development and the de novo evolution of genes in rice. Lastly, it discusses the role of artificial intelligence and machine learning in rice research and computational tools to analyze plant-pathogen co-evolution in rice crops.

WHO Classification of Tumours of the Breast

Sunil R. Lakhani,International Agency for Research on Cancer
WHO Classification of Tumours of the Breast Book PDF

Author : Sunil R. Lakhani,International Agency for Research on Cancer
Publisher : World Health Organization
Page : 240 pages
File Size : 40,7 Mb
Release : 2012
Category : Medical
ISBN : 9283224337

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WHO Classification of Tumours of the Breast by Sunil R. Lakhani,International Agency for Research on Cancer Pdf

WHO Classification of Tumours of the Breast is the fourth volume of the WHO series on histological and genetic typing of human tumours. This authoritative, concise reference book provides an international standard for oncologists and pathologists and will serve as an indispensable guide for use in the design of studies monitoring response to therapy and clinical outcome. Diagnostic criteria, pathological features, and associated genetic alterations are described in a strictly disease-oriented manner. Sections on all recognized neoplasms and their variants include new ICD-O codes, epidemiology, clinical features, macroscopy, pathology, genetics, and prognosis and predictive factors. The book, prepared by 90 authors from 24 countries, contains more than 340 colour photographs, tables and figures, and more than 1600 references.

Advances in Surgical Pathology: Breast Cancer

Omar Hameed,Shi Wei,Mohamed Mokhtar Desouki,Heidi Umphrey
Advances in Surgical Pathology Breast Cancer Book PDF

Author : Omar Hameed,Shi Wei,Mohamed Mokhtar Desouki,Heidi Umphrey
Publisher : Lippincott Williams & Wilkins
Page : 489 pages
File Size : 48,8 Mb
Release : 2015-04-28
Category : Medical
ISBN : 9781469883410

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Advances in Surgical Pathology: Breast Cancer by Omar Hameed,Shi Wei,Mohamed Mokhtar Desouki,Heidi Umphrey Pdf

The latest, groundbreaking addition to the Advances in Surgical Pathology series, Breast Cancer offers a thorough overview of the disease and the most recent data and technologies used in breast cancer surgery and diagnosis. Whether you’re a new or experienced pathologist or oncologist, or prepping for boards or certification, this is an irreplaceable volume.

Central Nervous System Tumours: Who Classification of Tumours

WHO Classification of Tumours Editorial Board
Central Nervous System Tumours Who Classification of Tumours Book PDF

Author : WHO Classification of Tumours Editorial Board
Publisher : WHO Classification of Tumours
Page : 584 pages
File Size : 55,9 Mb
Release : 2022-02-15
Category : Medical
ISBN : 9283245083

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Central Nervous System Tumours: Who Classification of Tumours by WHO Classification of Tumours Editorial Board Pdf

****When not purchasing directly from the official sales agents of the WHO, especially at online bookshops, please note that there have been issues with counterfeited copies. Buy only from known sellers and if there are quality issues, please contact the seller for a refund.***** The WHO Classification of Tumours Central Nervous System Tumours is the sixth volume in the 5th edition of the WHO series on the classification of human tumors. This series (also known as the WHO Blue Books) is regarded as the gold standard for the diagnosis of tumors and comprises a unique synthesis of histopathological diagnosis with digital and molecular pathology. These authoritative and concise reference books provide indispensable international standards for anyone involved in the care of patients with cancer or in cancer research, underpinning individual patient treatment as well as research into all aspects of cancer causation, prevention, therapy, and education. What's new in this edition? The 5th edition, guided by the WHO Classification of Tumours Editorial Board, will establish a single coherent cancer classification presented across a collection of individual volumes organized on the basis of anatomical site (digestive system, breast, soft tissue and bone, etc.) and structured in a systematic manner, with each tumor type listed within a taxonomic classification: site, category, family (class), type, and subtype. In each volume, the entities are now listed from benign to malignant and are described under an updated set of headings, including histopathology, diagnostic molecular pathology, staging, and easy-to-read essential and desirable diagnostic criteria. Who should read this book? Pathologists Neuro-oncologists Neuroradiologists Medical oncologists Radiation oncologists Neurosurgeons Oncology nurses Cancer researchers Epidemiologists Cancer registrars This volume Prepared by 199 authors and editors Contributors from around the world More than 1100 high-quality images More than 3600 references WHO Classification of Tumours Online The content of this renowned classification series is now also available in a convenient digital format by purchasing a subscription directly from IARC here.

WHO Classification of Breast Tumours

WHO Classification of Tumours Editorial Board
WHO Classification of Breast Tumours Book PDF

Author : WHO Classification of Tumours Editorial Board
Publisher : International Agency for Research on Cancer
Page : 0 pages
File Size : 43,5 Mb
Release : 2019-11-21
Category : Medical
ISBN : 9283245008

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WHO Classification of Breast Tumours by WHO Classification of Tumours Editorial Board Pdf

Table of contents : - TNM staging of carcinomas of the breast - 1. Introduction to tumours of the breast - 2. Epithelial tumours of the breast - 3. Fibroepithelial tumours and hamartomas of the breast - 4. Tumours of the nipple - 5. Mesenchymal tumours of the breast - 6. Haematolymphoid tumours of the breast - 7. Tumours of the male breast - 8. Metastases to the breast - 9. Genetic tumours syndromes of the breast.

Molecular Diagnosis of Cancer

Joseph E. Roulston,John M. S. Bartlett
Molecular Diagnosis of Cancer Book PDF

Author : Joseph E. Roulston,John M. S. Bartlett
Publisher : Springer Science & Business Media
Page : 389 pages
File Size : 51,5 Mb
Release : 2008-02-01
Category : Medical
ISBN : 9781592597604

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Molecular Diagnosis of Cancer by Joseph E. Roulston,John M. S. Bartlett Pdf

We are currently experiencing a fundamental shift in the way in which we approach the characterization of cancer. Never before has the make up of cancer tissues and individual cells been so exhaustively researched and char- terized. We are now capable of producing molecular “fingerprints” that ch- acterize the expression of all known and unknown genes within tumors and their surrounding tissues. More than 30,000 different genes may be measured in each patient’s tumor in a single experiment. Simultaneously, novel therapies that exploit the molecular roadmap have been developed and are now being offered to patients. These novel agents, such as Glivec, Herceptin, Iressa, and others, specifically target individual genes within tumors and can produce d- matic responses in some patients. These drugs are only the forerunners of a coming tidal wave of novel therapeutics that individually target specific m- ecules within cancer cells—more than 300 such agents are currently in phase I or II clinical trials. This is an exciting time for cancer specialists and patients alike. However, if we have learned anything from the past 50 or more years of research into cancer, it is that Lord Beaverbrook, in founding the British national health service in the 1950s, was frighteningly prescient when he defined the primary goal of health care to be “Diagnosis, Diagnosis, Diag- sis. ” Now, more than ever, it is essential that appropriate diagnostic methods and approaches are applied to the selection of patients for treatment.