A Modern Approach To Biofilm Related Orthopaedic Implant Infections

Author : Lorenzo Drago
Publisher : Springer
Page : 119 pages
File Size : 51,5 Mb
Release : 2017-05-16
Category : Medical
ISBN : 9783319522746

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A Modern Approach to Biofilm-Related Orthopaedic Implant Infections by Lorenzo Drago Pdf

This book discusses Prosthetic Joint Infection (PJI), which remains one of the most common problems necessitating revision arthroplasty. It pursues a multidisciplinary approach, bringing together opinions from the leading experts in the field. The book identifies the potential causes of these infections, provides sound diagnostic criteria guidelines, and explains how these prosthetic infections are managed from orthopedic surgery, clinical and diagnostic perspectives. PJI can lead to multiple revision surgeries and significant patient morbidity. Periprosthetic infection rates remain around 1–2% after primary total hip and knee arthroplasty and account for approximately 7–12% of all revision cases. Orthopedic hardware infections are much-feared and costly complications that can occur when these devices are implemented both in traumatic cases as well as in joint replacement surgery. Because these infections can lead to higher morbidity, it is important to understand their pathophysiology and the principles behind their diagnosis and initial treatment. The pathogenesis of these kinds of infections is intimately connected to the biofilm-producing trait characteristic of many microorganisms, which can have a critical effect on the likely success of treatments. The book offers a unique guide for all scientists working in arthroplasty who are seeking an update on the field, and for newcomers alike.

Author : Axel Cloeckaert,Karl Kuchler,Enea Gino Di Domenico,Fiorentina Ascenzioni,Catherine Dunyach-Remy,María Guembe
Publisher : Frontiers Media SA
Page : 134 pages
File Size : 41,5 Mb
Release : 2022-01-19
Category : Science
ISBN : 9782889740994

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Microbial Biofilms in Chronic and Recurrent Infections by Axel Cloeckaert,Karl Kuchler,Enea Gino Di Domenico,Fiorentina Ascenzioni,Catherine Dunyach-Remy,María Guembe Pdf

Author : Melanie Coathup
Publisher : Springer Nature
Page : 378 pages
File Size : 51,6 Mb
Release : 2022-02-01
Category : Medical
ISBN : 9783030832513

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Musculoskeletal Infection by Melanie Coathup Pdf

This book gathers international knowledge and contemporary clinical and scientific evidence on infections associated with the musculoskeletal system at a time when we are confronted with significant challenges and uncertainty. A key focus of the book is enhancing and advancing future discovery in the detection, prevention and treatment of musculoskeletal infection. This is an ideal book for physicians, surgeons, research scientists, university students, as well as medical and allied health students.

Author : Trisha Peel
Publisher : Springer
Page : 263 pages
File Size : 44,6 Mb
Release : 2017-11-28
Category : Medical
ISBN : 9783319652504

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Prosthetic Joint Infections by Trisha Peel Pdf

This book outlines the most updated clinical guidelines that are vital for the prevention infections and care of patients with joint infections following a replacement surgery, one of the highest volume medical interventions globally. Sections address the diagnosis, management approaches and prevention of prosthetic joint infections. Written by experts in the field, this text provides a brief overview of the literature and current recommendations in each of the specified areas. Given the rapidly evolving state-of-play in this clinical area, this compendium grows increasingly important to clinicians in their management decisions. Prosthetic Joint Infections is a valuable resource for infectious disease specialists, epidemiologists, surgeons, and orthopedic specialists who may work with patients with prosthetic joint infections.

Author : Aldo R. Boccaccini,P.X. Ma,Liliana Liverani
Publisher : Woodhead Publishing
Page : 890 pages
File Size : 43,5 Mb
Release : 2021-10-27
Category : Technology & Engineering
ISBN : 9780128205792

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Tissue Engineering Using Ceramics and Polymers by Aldo R. Boccaccini,P.X. Ma,Liliana Liverani Pdf

Tissue Engineering Using Ceramics and Polymers, Third Edition is a valuable reference tool for both academic researchers and scientists involved in biomaterials or tissue engineering, including the areas of bone and soft-tissue reconstruction, repair and organ regeneration. With its distinguished editors and international team of contributors, this book reviews the latest research and advances in this thriving area and how they can be used to develop treatments for disease states. New sections cover nanobiomaterials, drug delivery, advanced imaging and MRI for tissue engineering, and characterization of vascularized scaffolds. Technology and research in the field of tissue engineering has drastically increased within the last few years to the extent that almost every tissue and organ of the human body could potentially be regenerated with the aid of biomaterials. Provides updated and new information on ceramic and polymer biomaterials for tissue engineering Presents readers with systematic coverage of the processing, characterization and modeling of each material Includes content that will be relevant to a range of readers, including biomedical engineers, materials scientists, and those interested in regenerative medicine

Author : Thomas Bjarnsholt,Peter Østrup Jensen,Claus Moser,Niels Høiby
Publisher : Springer
Page : 0 pages
File Size : 48,6 Mb
Release : 2014-10-11
Category : Science
ISBN : 1489982280

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Biofilm Infections by Thomas Bjarnsholt,Peter Østrup Jensen,Claus Moser,Niels Høiby Pdf

This book will cover both the evidence for biofilms in many chronic bacterial infections as well as the problems facing these infections such as diagnostics and treatment regimes. A still increasing interest and emphasis on the sessile bacterial lifestyle biofilms has been seen since it was realized that that less than 0.1% of the total microbial biomass lives in the planktonic mode of growth. The term was coined in 1978 by Costerton et al. who defined the term biofilm for the first time.In 1993 the American Society for Microbiology (ASM) recognised that the biofilmmode of growth was relevant to microbiology. Lately many articles have been published on the clinical implications of bacterial biofilms. Both original articles and reviews concerning the biofilm problem are available.

Author : Dustin L. Williams
Publisher : Springer
Page : 162 pages
File Size : 42,5 Mb
Release : 2020-11-15
Category : Medical
ISBN : 3030306690

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Targeting Biofilms in Translational Research, Device Development, and Industrial Sectors by Dustin L. Williams Pdf

This book offers a much-needed discussion on the targeting of biofilm-related infections. Chapters include discussions on the impact of biofilm on medical implants, industrial applications, as well as wound and tissue infections. It also offers discussions on regulatory management for industrial sectors and medical environments. Given that there continues to be a paucity of effective antimicrobial products, devices, and coatings in clinical and industrial use that effectively reduce rates of infection or biofilm-related problems, Targeting Biofilms in Translational Research, Device Development, and Industrial Sectors, offers a fresh and much-needed perspective aimed at helping create healthier controlled environments and safer devices. This comprehensive book is indispensable for industrial and academic translational researchers, device developers, and regulatory experts looking to create more effective antimicrobial products.

Author : W. Zimmerli
Publisher : John Wiley & Sons
Page : 429 pages
File Size : 51,9 Mb
Release : 2015-01-27
Category : Science
ISBN : 9781118581773

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Bone and Joint Infections by W. Zimmerli Pdf

Infections of the bones (osteomyelitis) and joints (septic arthritis) are serious health problems which require antibiotics and often surgery. Awareness among health professionals of the causes and treatment options for various types of bone and joint infections is essential for effective resolution. Bone and Joint Infections takes a multidisciplinary approach in covering the diagnostic and therapeutic treatment of osteomyelitis and septic arthritis, including different types of implant-associated infections. Correct and rapid diagnosis of bone and joint infection is crucial, and requires the input of a variety of specialists. Bone and Joint Infection takes a similarly collaborative and comprehensive approach, including chapters authored by clinicians, laboratory specialists, and surgeons. Covering the basic microbiology and clinical aspects of bone and joint infection, this book will be a valuable resource both for researchers in the lab and for physicians and surgeons seeking a comprehensive reference on osteomyelitis and septic arthritis.

Author : Dominik Duscher,Melvin A. Shiffman
Publisher : Springer Nature
Page : 466 pages
File Size : 45,9 Mb
Release : 2019-11-26
Category : Science
ISBN : 9783030199586

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Regenerative Medicine and Plastic Surgery by Dominik Duscher,Melvin A. Shiffman Pdf

This book discusses the current research concepts and the emerging technologies in the field of stem cells and tissue engineering. It is the first authoritative reference documenting all the ways that plastic surgical practice and regenerative medicine science overlap or provide a road map for the future of both specialties. The Editors have provided a valuable service by gathering in one place the leading voices in these two fields in clear and concise manner. Divided into five parts, the book opens with a description of the elements of regenerative medicine including definitions, basic principles of soft and bone tissue regeneration, biomaterials and scaffolds. Current research concepts are explored in the second part of this book, for example mechanotransduction and the utility of extracellular vesicles. In the third part, the editors present the emerging technologies and highlight the novel perspectives on bionic reconstruction and biomimetics in surgery and regenerative medicine. Part four deals with translational aspects including practical information on moving scientific findings from bench to bedside. The final part then describes in detail applications in clinical plastic surgery. Written by leading experts this book is an invaluable resource for researchers, students, beginners and experienced clinicians in a range of specialties. "In your hands is a comprehensive encyclopedia of two rapidly converging fields. Drs Duscher and Shiffman have done an outstanding job of highlighting the interdependent relationship between plastic surgery and regenerative medicine. Ultimately, this is to the benefit of both fields." - Geoffrey C. Gurtner, MD, FACS Johnson and Johnson Distinguished Professor of Surgery Professor (by courtesy) of Bioengineering and Materials Science Inaugural Vice Chairman of Surgery for Innovation Stanford University School of Medicine

Author : David Schlossberg
Publisher : Springer Science & Business Media
Page : 196 pages
File Size : 54,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461238706

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Orthopedic Infection by David Schlossberg Pdf

This comprehensive, clinically oriented reference details the state-of-the-art approach to infections of bones and joints. Utility for all practitioners is ensured by the wide range of contributors who include infectious disease specialists, rheumatologists, orthopedic surgeons, and radiologists. This is the definitive resource for the clinician who treats orthopedic infections.

Author : Ying Deng,Wei Lv
Publisher : Woodhead Publishing
Page : 238 pages
File Size : 41,7 Mb
Release : 2016-10-24
Category : Technology & Engineering
ISBN : 9780081003985

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Biofilms and Implantable Medical Devices by Ying Deng,Wei Lv Pdf

Biofilms and Implantable Medical Devices: Infection and Control explores the increasing use of permanent and semi-permanent implants and indwelling medical devices. As an understanding of the growth and impact of biofilm formation on these medical devices and biomaterials is vital for protecting the health of the human host, this book provides readers with a comprehensive treatise on biofilms and their relationship with medical devices, also reporting on infections and associated strategies for prevention. Provides useful information on the fundamentals of biofilm problems in medical devices Discusses biofilm problems in a range of medical devices Focuses on strategies for prevention of biofilm formation

Author : William G. Characklis,P. A. Wilderer
Publisher : Wiley-Blackwell
Page : 412 pages
File Size : 53,5 Mb
Release : 1989
Category : Science
ISBN : UOM:39015017731376

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Structure and Function of Biofilms by William G. Characklis,P. A. Wilderer Pdf

Structure and Function of Biofilms W.G. Characklis P.A. Wilderer Editors Biofilms, the accumulation of microorganisms at surfaces (e.g. a rock, a heat exchanger tube, an oil droplet, a tooth, or a medical implant) play an important role in nature and have recently received increasing attention in science as well as in technology. This volume contains a summary of the current state of knowledge concerning the behavior of microorganisms in a biofilm and their physical, chemical, and biological interactions with each other and with the environment at both the biofilm—substratum and the biofilm—bulk liquid interfaces. New techniques to investigate biofilms and to predict the performance of biofilm systems are presented and future research needs are identified. An excellent source of information for microbiologists, medical scientists and engineers is provided.

Author : Margaret Jean Hall
Publisher : Unknown
Page : 24 pages
File Size : 47,7 Mb
Release : 2000
Category : Hospital surveys
ISBN : MINN:31951D03735503L

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1998 Summary by Margaret Jean Hall Pdf

Author : Mahmood Aliofkhazraei
Publisher : BoD – Books on Demand
Page : 242 pages
File Size : 40,6 Mb
Release : 2013-05-22
Category : Technology & Engineering
ISBN : 9789535111498

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Modern Surface Engineering Treatments by Mahmood Aliofkhazraei Pdf

Surface engineering can be defined as an enabling technology used in a wide range of industrial activities. Surface engineering was founded by detecting surface features which destroy most of pieces, e.g. abrasion, corrosion, fatigue, and disruption; then it was recognized, more than ever, that most technological advancements are constrained with surface requirements. In a wide range of industry (such as gas and oil exploitation, mining, and manufacturing), the surfaces generate an important problem in technological advancement. Passing time shows us new interesting methods in surface engineering. These methods usually apply to enhance the surface properties, e.g. wear rate, fatigue, abrasion, and corrosion resistance. This book collects some of new methods in surface engineering.

Author : Mark Shirtliff,Jeff G. Leid
Publisher : Springer Science & Business Media
Page : 276 pages
File Size : 49,5 Mb
Release : 2008-12-19
Category : Medical
ISBN : 9783540681199

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The Role of Biofilms in Device-Related Infections by Mark Shirtliff,Jeff G. Leid Pdf

Approximately 60% of all hospital-associated infections, over one million cases per year, are due to biofilms that have formed on indwelling medical devices. Device-related biofilm infections increase hospital stays and add over one billion dollars/year to U.S. hospitalization costs. Since the use and the types of indwelling medical devices commonly used in modern healthcare are continuously expanding, especially with an aging population, the incidence of biofilm infections will also continue to rise. The central problem with microbial biofilm infections of foreign bodies is their propensity to resist clearance by the host immune system and all antimicrobial agents tested to date. In fact, compared to their free floating, planktonic counterparts, microbes within a biofilm are 50 – 500 times more resistant to antimicrobial agents. Therefore, achieving therapeutic and non-lethal dosing regimens within the human host is impossible. The end result is a conversion from an acute infection to one that is persistent, chronic, and recurrent, most often requiring device removal in order to eliminate the infection. This text will describe the major types of device-related infections, and will explain the host, pathogen, and the unique properties of their interactions in order to gain a better understanding of these recalcitrant infections.