A Pharmacology Primer

Author : Terry Kenakin
Publisher : Elsevier
Page : 318 pages
File Size : 47,8 Mb
Release : 2010-07-26
Category : Medical
ISBN : 0080465307

Get Book

A Pharmacology Primer by Terry Kenakin Pdf

The Second Edition will continue this tradition of better preparing researchers in the basics of pharmacology. In addition, new human interest material including historical facts in pharmacology will be added. A new section on therapeutics will help readers identify with diseases and drug treatments. Over 30 new figures and tables More human interest information to provide readers with historical facts on pharmacology research New section on therapeutics to help identify diseaes and drug treatments New section on new biological concepts relevant to pharmacological research (i.e., systems biology) New study sections organized with ASPET and other international pharmacology organizations New coverage of pharmacokinetics and drug disposition

Author : Terry Kenakin
Publisher : Academic Press
Page : 488 pages
File Size : 49,6 Mb
Release : 2018-10-26
Category : Medical
ISBN : 9780128139585

Get Book

A Pharmacology Primer by Terry Kenakin Pdf

A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, Fifth Edition features the latest ideas and research regarding the application of pharmacology to the process of drug discovery. Written by well-respected pharmacologist, Terry P. Kenakin, this primer is an indispensable resource for all those involved in drug discovery. This updated edition has been thoroughly revised to include material on quantifying drug efficacy through bias and cluster analysis, the impact of molecular dynamics and protein structural analysis, the real time kinetic analysis of drug effect, virtual screening for new drug chemical scaffolds, and much more. With full color illustrations and new examples throughout, this book remains a top reference for all industry and academic scientists that is also ideal for students directly involved in drug discovery or pharmacologic research. Highlights changes surrounding strategies for drug discovery, providing a comprehensive reference and featuring advances in the methods involved Includes multiple new sections, such as development and utilization of models in pharmacology, de-orphanization of new drug targets, predicting impact of disease on drug pharmacokinetics, and the impact of enzyme kinetics on drug-drug interactions Illustrates the application of rapid inexpensive assays to predict activity in the therapeutic setting, showing data outcomes and the limitations inherent in interpreting this data

Author : Terry Kenakin
Publisher : Academic Press
Page : 416 pages
File Size : 47,8 Mb
Release : 2009-02-07
Category : Medical
ISBN : 008092333X

Get Book

A Pharmacology Primer by Terry Kenakin Pdf

This successful guide assists scientists trained in molecular biology and related fields who now need to know the basic theories, principles and practical applications of pharmacology. This latest edition continues the tradition of better preparing researchers in the basics of pharmacology. With expanded hands-on exercises and the addition of Pharmacokinetics coverage, new human interest material including historical facts in pharmacology and a new section on therapeutics that will help readers identify with diseases and drug treatments. The ideal book for researchers in drug discovery who have seen their role shift from "individual" to "team player" where that team includes chemists, biologists, and others with strong, but varied, science backgrounds who must now work together toward their common pharmacology goal. At GlaxoSmithKline, a pharmaceuticals world-leader, Terry Kenakin regularly teaches a course for their research scientists and has drawn on his experience to create a pharmacology primer. *New - Latest coverage of the chemistry of drugs including expanded coverage of the pharmacokinetic discussion of druglike properties -- Increases reader understanding of necessary ADME (Absorption, Distribution, Metabolism, and Excretion) properties and increases the rate of drug approval and acceptance. *Context - Unique discussions on various drug discovery teams and the role of the chemist on those teams -- Promotes the understanding of these expanding roles and responsibilities and how to maximize the effective contributions of each matrix team member. *Real-world learning - There are hands-on exercises, with extensive answers, utilizing real data on structure activity relationships; utilization of pharmacological principles to make general statements about how changes in structure lead to changes in drug activity. + hands on exercises with extensive answers on Pharmacokinetics -- Stengthens practical application and understanding of core concepts and principles. *Study sections are organized with ASPET (American Society for Pharmacology and Experimental Therapeutics)and other international organizations -- Ensures that learning follows professional industry standards.

Author : TERRY. KENAKIN
Publisher : Unknown
Page : 0 pages
File Size : 40,5 Mb
Release : 2023
Category : Electronic
ISBN : 0323983790

Get Book

PHARMACOLOGY PRIMER. by TERRY. KENAKIN Pdf

Author : Terry Kenakin
Publisher : Academic Press
Page : 0 pages
File Size : 40,5 Mb
Release : 2018-11-05
Category : Medical
ISBN : 0128139579

Get Book

A Pharmacology Primer by Terry Kenakin Pdf

A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, Fifth Edition features the latest ideas and research regarding the application of pharmacology to the process of drug discovery. Written by well-respected pharmacologist, Terry P. Kenakin, this primer is an indispensable resource for all those involved in drug discovery. This updated edition has been thoroughly revised to include material on quantifying drug efficacy through bias and cluster analysis, the impact of molecular dynamics and protein structural analysis, the real time kinetic analysis of drug effect, virtual screening for new drug chemical scaffolds, and much more. With full color illustrations and new examples throughout, this book remains a top reference for all industry and academic scientists that is also ideal for students directly involved in drug discovery or pharmacologic research.

Author : Robert M. Julien, Ph.D.
Publisher : Holt Paperbacks
Page : 514 pages
File Size : 53,6 Mb
Release : 2013-08-06
Category : Health & Fitness
ISBN : 9781466851184

Get Book

A Primer of Drug Action by Robert M. Julien, Ph.D. Pdf

Since 1975, Robert Julien's A Primer of Drug Action has been the definitive guide to the effects of psychoactive drugs on the brain and on behavior. Now fully updated, this popular guide continues to lead the way through a rapidly changing field, providing readers with a clear, contemporary, and objective look at every drug and medication that either positively or adversely affects brain function. This edition includes important new information on: -Herbal medications -Drug therapy for behavioral and anxiety disorders -Clinical practice guidelines for treating psychological disorders -Depression and the action of antidepressant drugs -The use of newer anticonvulsants in the treatment of bipolar disorder, pain syndromes, and behavioral disorders -Drug therapy for children, adolescents and the elderly -"New generation" antipsychotic agents Authoritative, comprehensive, and suitable for those with little background in biology, A Primer of Drug Action is an indispensable source of information for anyone interested in drug use, abuse, and education.

Author : David R. Bright,Mary F. Powers
Publisher : Morton Publishing Company
Page : 359 pages
File Size : 55,6 Mb
Release : 2012-01-01
Category : Medical
ISBN : 9781617310904

Get Book

Medication Workbook for Pharmacy Technicians: A Pharmacology Primer by David R. Bright,Mary F. Powers Pdf

Officially endorsed by the American Pharmacists Association (APhA), this practical workbook provides a basic introduction to pharmacology and reinforces the use of medications for prospective technicians to work in a pharmacy and to help prepare them for the pharmacy technician national certification exams.

Author : P. J. Bentley
Publisher : Cambridge University Press
Page : 170 pages
File Size : 50,9 Mb
Release : 1981-08-31
Category : Medical
ISBN : 0521280745

Get Book

Elements of Pharmacology by P. J. Bentley Pdf

Written primarily for students of medicine, pharmacy, and pharmacology, this introductory book provides a concise summary of the principles that underlie the science of pharmacology. It presents the basic concepts required for understanding the use, mechanisms of action, toxicity and side effects, and therapeutic application of drugs in man. Thus the book may also be of interest to medical practitioners and to biological and medical scientists. Among topics covered are the sources of drugs, the way they are administered and dealt with in the body, as well as concepts about the nature of their actions. The last include their chemical interactions with components of cells and the manner in which these lead to therapeutically desirable as well as undesirable and even toxic effects. In addition, clinically related subjects, such as drug interactions, teratogenic and carcinogenic effects are discussed. The development and testing of new drugs are also described. For easy reference, at the back of the book there is a glossary of drugs named in the text.

Author : Deluca
Publisher : Unknown
Page : 128 pages
File Size : 50,6 Mb
Release : 2012-11-01
Category : Electronic
ISBN : 0763758205

Get Book

The Pharmacology Primer by Deluca Pdf

Author : Thorsteinn Loftsson
Publisher : Academic Press
Page : 178 pages
File Size : 53,5 Mb
Release : 2015-03-25
Category : Medical
ISBN : 9780128014912

Get Book

Essential Pharmacokinetics by Thorsteinn Loftsson Pdf

Essential Pharmacokinetics: A Primer for Pharmaceutical Scientists is an introduction to the concepts of pharmacokinetics intended for graduate students and new researchers working in the pharmaceutical sciences. This book describes the mathematics used in the mammillary model as well as the application of pharmacokinetics to pharmaceutical product development, and is useful as both a self-study and classroom resource. Content coverage includes detailed discussions of common models and important pharmacokinetic concepts such as biological half-life, clearance, excretion, multiple dosage regimens and more. Numerous equations, practical examples and figures are incorporated to clearly illustrate the theoretical background of pharmacokinetic behavior of drugs and excipients. Shows how to apply basic pharmacokinetic methods to evaluate drugs, excipients and drug products Uses guided practice questions, mathematical concepts and real-world examples for self-assessment and retention purposes Illustrates how to write and evaluate drug registration files

Author : George J. Christ,Karl-Erik Andersson
Publisher : Cambridge University Press
Page : 361 pages
File Size : 41,6 Mb
Release : 2013-04-15
Category : Medical
ISBN : 9781107354739

Get Book

Regenerative Pharmacology by George J. Christ,Karl-Erik Andersson Pdf

Regenerative medicine is broadly defined as the repair or replacement of damaged cells, tissues and organs. It is a multidisciplinary effort in which technologies derive from the fields of cell, developmental and molecular biology; chemical and material sciences (i.e. nanotechnology); engineering; surgery; transplantation; immunology; molecular genetics; physiology; and pharmacology. As regenerative medicine technologies continue to evolve and expand across the boundaries of numerous scientific disciplines, they remain at the forefront of the translational research frontier with the potential to radically alter the treatment of a wide variety of disease and dysfunction. This book will draw attention to the critical role that pharmacological sciences will undeniably play in the advancement of these treatments. This book is invaluable for advanced students, postdoctoral fellows, researchers new to the field of regenerative medicine/tissue engineering, and experienced investigators looking for new research avenues. The first state-of-the-art book in this rapidly evolving field of research.

Author : Geoffrey Currie
Publisher : Unknown
Page : 128 pages
File Size : 51,7 Mb
Release : 2020-11
Category : Electronic
ISBN : 0932004970

Get Book

Pharmacology Primer for Medications in Nuclear Medicine and Medical Imaging by Geoffrey Currie Pdf

Author : Thomas Byrne,Alan Poling
Publisher : New Harbinger Publications
Page : 254 pages
File Size : 50,5 Mb
Release : 2000-05-01
Category : Medical
ISBN : 9781608826735

Get Book

Introduction to Behavioral Pharmacology by Thomas Byrne,Alan Poling Pdf

There are hundreds, if not thousands, of substances that are used to modify behavior. While different classes of substances have known effects, one has only to see a group of people drinking to excess to recognize that not everyone responds in the same way to a given substance. Why do substances have the behavioral effects they do, and why do individuals vary in their responses to them? This book provides a conceptual framework for answering such questions. Introduction to Behavioral Pharmacology includes a short overview of behavioral analysis and general pharmacology, followed by detailed discussion of assessment of drug effects, the stimulus properties of drugs, drug abuse, and more.

Author : Jerika T. Lam,Mary A Gutierrez
Publisher : McGraw Hill Professional
Page : 186 pages
File Size : 45,6 Mb
Release : 2020-12-22
Category : Medical
ISBN : 9781260457117

Get Book

Pharmacogenomics: A Primer for Clinicians by Jerika T. Lam,Mary A Gutierrez Pdf

An invaluable resource to the rapidly emerging field of pharmacogenomics—complete with case studies, clinical pearls, and treatment recommendations The aim of pharmacogenomics is to improve personalized medicine by taking into account how genes affect an individual’s tolerability and response to drugs. Approaching pharmacogenomics from the current clinical, scientific, and implementation perspectives, this guide serves as an invaluable evidence-based resource to the subject. Reflecting the shift from genetics to genomics in the pharmaceutical sphere, the book covers pharmacogenomics fundamentals; genotyping tests and evidence; clinical implementation; ethical, legal, and social issues; and more. You’ll also find illuminating case scenarios, clinical pearls, and evidence-based recommendations for treatments and alternatives based on CPIC, PharmGKB, and FDA guidelines.

Author : Anonim
Publisher : Unknown
Page : 0 pages
File Size : 47,9 Mb
Release : 1975
Category : Psychopharmacology
ISBN : LCCN:74023271

Get Book

A Primer of Drug Action by Anonim Pdf