A Primer Of Drug Action

Author : Robert M. Julien, Ph.D.
Publisher : Holt Paperbacks
Page : 514 pages
File Size : 47,5 Mb
Release : 2013-08-06
Category : Health & Fitness
ISBN : 9781466851184

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A Primer of Drug Action by Robert M. Julien, Ph.D. Pdf

Since 1975, Robert Julien's A Primer of Drug Action has been the definitive guide to the effects of psychoactive drugs on the brain and on behavior. Now fully updated, this popular guide continues to lead the way through a rapidly changing field, providing readers with a clear, contemporary, and objective look at every drug and medication that either positively or adversely affects brain function. This edition includes important new information on: -Herbal medications -Drug therapy for behavioral and anxiety disorders -Clinical practice guidelines for treating psychological disorders -Depression and the action of antidepressant drugs -The use of newer anticonvulsants in the treatment of bipolar disorder, pain syndromes, and behavioral disorders -Drug therapy for children, adolescents and the elderly -"New generation" antipsychotic agents Authoritative, comprehensive, and suitable for those with little background in biology, A Primer of Drug Action is an indispensable source of information for anyone interested in drug use, abuse, and education.

Author : Robert M. Julien
Publisher : Unknown
Page : 548 pages
File Size : 47,9 Mb
Release : 1998
Category : Psychopharmaciology
ISBN : 0716731134

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A Primer of Drug Action by Robert M. Julien Pdf

Since 1975, Robert Julien's A Primer of Drug Action has been the definitive guide to the effects of psychoactive drugs on the brain and on behavior. Now in its Ninth Edition, with over 40% of its references dated from between 1998 and 2000, this popular guide continues to lead the way through a rapidly changing field, providing readers with a clear, contemporary, and objective look at every drug and medication that either positively or adversely affects brain function. These include antidepressants, sedatives, opiods, alcohol, marijuana, anabolic steroids, antimanic drugs, hallucinogens, and many others.A Primer of Drug Action, Ninth Edition includes important new information on* Herbal medications* Drug therapy for behavioral and anxiety disorders* Clinical practice guidelines for treating psychological disorders* Depression and the action of antidepressant drugs* The use of newer anticonvulsants in the treatment of bipolar disorder, pain syndromes, and behavioral disorders* Drug therapy for children, adolescents, and the elderly* New generation antipsychotic agents* Treatments for people who both abuse drugs and suffer from psychological disorders such as anxiety and depressionAuthoritative, comprehensive, and suitable for those with little background in biology, A Primer of Drug Action, Ninth Edition is an indispensable source of information for anyone interested in drug use, abuse, and education.

Author : Claire D. Advokat,Robert Julien,Joseph Comaty
Publisher : Worth
Page : 672 pages
File Size : 55,6 Mb
Release : 2019-01-17
Category : Psychology
ISBN : 1319248942

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Julien's Primer of Drug Action by Claire D. Advokat,Robert Julien,Joseph Comaty Pdf

Julien’s Primer of Drug Action continues to evolve side by side with the field it covers providing a thoroughly up to date look at psychotherapeutic and recreational drugs, including the latest research and the newest formulations. The thoroughly updated 14th edition features: New coverage of opioids of abuse, and drugs used to treat of opioid dependence and opioid overdose New research on the use of marijuana to treat Alzheimers, PTSD, and Epilepsy New coverage of pharmacological, physiological, and psychoactive effects of synthetic marijuana including its toxicity New research on Cannabidiol (CBD) and its therapeutic uses New research of the efficacy of antipsychotics to treat dementia, Parkinson’s, bipolar, OCD, and PTSD The use of genetic testing to predict effectiveness of antidepressant treatment New research on the use of ketamine for the treatment of depression

Author : Robert M. Julien
Publisher : Worth Publishers
Page : 0 pages
File Size : 52,7 Mb
Release : 2007-10-12
Category : Psychology
ISBN : 1429206799

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A Primer of Drug Action by Robert M. Julien Pdf

From its first edition 30 years ago, Robert Julien’s A Primer of Drug Action has evolved side by side with the field it covers, capturing the current state of the science of psychopharmacology with each new edition. Furthering that tradition, the new edition takes its place as the definitive guide to the pharmacology of drugs that affect the mind and behavior as understood today. With over 40% new research citations, there is no clearer, more current presentation available on the mechanisms of drug action, etiologies of major psychological disorders, rationales for drug treatment, and the uses of psychopharmacology in patient care.

Author : P. J. Bentley
Publisher : Cambridge University Press
Page : 170 pages
File Size : 54,5 Mb
Release : 1981-08-31
Category : Medical
ISBN : 0521280745

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Elements of Pharmacology by P. J. Bentley Pdf

Written primarily for students of medicine, pharmacy, and pharmacology, this introductory book provides a concise summary of the principles that underlie the science of pharmacology. It presents the basic concepts required for understanding the use, mechanisms of action, toxicity and side effects, and therapeutic application of drugs in man. Thus the book may also be of interest to medical practitioners and to biological and medical scientists. Among topics covered are the sources of drugs, the way they are administered and dealt with in the body, as well as concepts about the nature of their actions. The last include their chemical interactions with components of cells and the manner in which these lead to therapeutically desirable as well as undesirable and even toxic effects. In addition, clinically related subjects, such as drug interactions, teratogenic and carcinogenic effects are discussed. The development and testing of new drugs are also described. For easy reference, at the back of the book there is a glossary of drugs named in the text.

Author : Terry Kenakin
Publisher : Academic Press
Page : 488 pages
File Size : 53,9 Mb
Release : 2018-10-26
Category : Medical
ISBN : 9780128139585

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A Pharmacology Primer by Terry Kenakin Pdf

A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, Fifth Edition features the latest ideas and research regarding the application of pharmacology to the process of drug discovery. Written by well-respected pharmacologist, Terry P. Kenakin, this primer is an indispensable resource for all those involved in drug discovery. This updated edition has been thoroughly revised to include material on quantifying drug efficacy through bias and cluster analysis, the impact of molecular dynamics and protein structural analysis, the real time kinetic analysis of drug effect, virtual screening for new drug chemical scaffolds, and much more. With full color illustrations and new examples throughout, this book remains a top reference for all industry and academic scientists that is also ideal for students directly involved in drug discovery or pharmacologic research. Highlights changes surrounding strategies for drug discovery, providing a comprehensive reference and featuring advances in the methods involved Includes multiple new sections, such as development and utilization of models in pharmacology, de-orphanization of new drug targets, predicting impact of disease on drug pharmacokinetics, and the impact of enzyme kinetics on drug-drug interactions Illustrates the application of rapid inexpensive assays to predict activity in the therapeutic setting, showing data outcomes and the limitations inherent in interpreting this data

Author : Terry Kenakin
Publisher : Elsevier
Page : 318 pages
File Size : 40,6 Mb
Release : 2010-07-26
Category : Medical
ISBN : 0080465307

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A Pharmacology Primer by Terry Kenakin Pdf

The Second Edition will continue this tradition of better preparing researchers in the basics of pharmacology. In addition, new human interest material including historical facts in pharmacology will be added. A new section on therapeutics will help readers identify with diseases and drug treatments. Over 30 new figures and tables More human interest information to provide readers with historical facts on pharmacology research New section on therapeutics to help identify diseaes and drug treatments New section on new biological concepts relevant to pharmacological research (i.e., systems biology) New study sections organized with ASPET and other international pharmacology organizations New coverage of pharmacokinetics and drug disposition

Author : Robert M. Julien
Publisher : Unknown
Page : 305 pages
File Size : 46,8 Mb
Release : 1985
Category : Psychopharmacologie
ISBN : 071671714X

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A Primer of Drug Action by Robert M. Julien Pdf

Author : Robert M. Julien
Publisher : Unknown
Page : 716 pages
File Size : 46,6 Mb
Release : 2011
Category : Psychopharmacology
ISBN : OCLC:1285751697

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A Primer of Drug Action by Robert M. Julien Pdf

Author : Alex S. Evers,Mervyn Maze,Evan D. Kharasch
Publisher : Cambridge University Press
Page : 128 pages
File Size : 52,9 Mb
Release : 2011-03-10
Category : Medical
ISBN : 9781139497022

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Anesthetic Pharmacology by Alex S. Evers,Mervyn Maze,Evan D. Kharasch Pdf

In recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the practice of anesthesiology has expanded to the preoperative environment and numerous locations outside the OR. Anesthetic Pharmacology: Basic Principles and Clinical Practice, 2nd edition, is an outstanding therapeutic resource in anesthesia and critical care: Section 1 introduces the principles of drug action, Section 2 presents the molecular, cellular and integrated physiology of the target organ/functional system and Section 3 reviews the pharmacology and toxicology of anesthetic drugs. The new Section 4, Therapeutics of Clinical Practice, provides integrated and comparative pharmacology and the practical application of drugs in daily clinical practice. Edited by three highly acclaimed academic anesthetic pharmacologists, with contributions from an international team of experts, and illustrated in full colour, this is a sophisticated, user-friendly resource for all practitioners providing care in the perioperative period.

Author : Ross L. Stein
Publisher : John Wiley & Sons
Page : 322 pages
File Size : 53,8 Mb
Release : 2011-08-08
Category : Science
ISBN : 9781118084403

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Kinetics of Enzyme Action by Ross L. Stein Pdf

Few scientists have the knowledge to perform the studies that are necessary to discover and characterize enzyme inhibitors, despite the vested interest the pharmaceutical industry has in this field. Beginning with the most basic principles pertaining to simple, one-substrate enzyme reactions and their inhibitors, and progressing to a thorough treatment of two-substrate enzymes, Kinetics of Enzyme Action: Essential Principles for Drug Hunters provides biochemists, medicinal chemists, and pharmaceutical scientists with numerous case study examples to outline the tools and techniques necessary to perform, understand, and interpret detailed kinetic studies for drug discovery.

Author : Margareta Hammarlund-Udenaes,Elizabeth C.M. de Lange,Robert G. Thorne
Publisher : Springer Science & Business Media
Page : 731 pages
File Size : 48,7 Mb
Release : 2013-12-03
Category : Medical
ISBN : 9781461491057

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Drug Delivery to the Brain by Margareta Hammarlund-Udenaes,Elizabeth C.M. de Lange,Robert G. Thorne Pdf

The development of new CNS drugs is notoriously difficult. Drugs must reach CNS target sites for action and these sites are protected by a number of barriers, the most important being the blood –brain barrier (BBB). Many factors are therefore critical to consider for CNS drug delivery, e.g. active/passive transport across the BBB, intra-brain distribution, and central/systemic pharmacokinetics, to name a few. Neurological disease and trauma conditions add further complexity because CNS barriers, drug distribution and pharmacokinetics are dynamic and often changed by disease/trauma. Knowledge of all these factors and their interplay in different conditions is of utmost importance for proper CNS drug development and disease treatment. In recent years much information has become available for a better understanding of the many factors important for CNS drug delivery and how they interact to affect drug action. This book describes small and large drug delivery to the brain with an emphasis on the physiology of the BBB and the principles and concepts for drug delivery across the BBB and distribution within the brain. It contains methods descriptions for studying drug delivery, routes and approaches of administering drugs into the brain, the influence of disease, and drug industry perspectives. Therewith, it contributes to an in-depth understanding of the interplay between brain (patho)-physiology and drug characteristics. Furthermore, the content is designed to be both cutting-edge and educational, so that the book can be used in high-level training of academic and industry scientists with full references to original publications. ​

Author : R. W. Ryall
Publisher : Cambridge University Press
Page : 256 pages
File Size : 47,9 Mb
Release : 1989-05-25
Category : Medical
ISBN : 0521254248

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Mechanisms of Drug Action on the Nervous System by R. W. Ryall Pdf

Drugs affecting the nerves and the brain are among the most commonly used in contemporary medicine. This study examines the mechanisms by which such substances cause their therapeutic or undesirable side-effects in relation to underlying processes and pathological phenomena. The book fills the information gap between large textbooks and highly specialized reviews and monographs. Mechanisms of drug actions are examined mainly at the cellular and subcellular levels. Molecular, neurochemical and electrophysiological approaches are used in an attempt to provide a rational study of drugs acting on the nervous system.

Author : Shiew-Mei Huang,Juan J.L. Lertora,Paolo Vicini,Arthur J. Atkinson Jr.
Publisher : Academic Press
Page : 764 pages
File Size : 53,6 Mb
Release : 2021-10-16
Category : Medical
ISBN : 9780128198841

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Atkinson's Principles of Clinical Pharmacology by Shiew-Mei Huang,Juan J.L. Lertora,Paolo Vicini,Arthur J. Atkinson Jr. Pdf

Atkinson’s Principles of Clinical Pharmacology, Fourth Edition is the essential reference on the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This well-regarded survey continues to focus on the basics of clinical pharmacology for the development, evaluation and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the fourth edition has been thoroughly updated to provide readers with an ideal reference on the wide range of important topics impacting clinical pharmacology. Presents the essential knowledge for effective practice of clinical pharmacology Includes a new chapter and extended discussion on the role of personalized and precision medicine in clinical pharmacology Offers an extensive regulatory section that addresses US and international issues and guidelines Provides extended coverage of earlier chapters on transporters, pharmacogenetics and biomarkers, along with further discussion on "Phase 0" studies (microdosing) and PBPK

Author : Mark Muse,Bret A. Moore
Publisher : John Wiley & Sons
Page : 532 pages
File Size : 53,9 Mb
Release : 2012-03-22
Category : Psychology
ISBN : 9781118235089

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Handbook of Clinical Psychopharmacology for Psychologists by Mark Muse,Bret A. Moore Pdf

Praise for Handbook of Clinical Psychopharmacology for Psychologists "Handbook of Clinical Psychopharmacology for Psychologists is a remarkably thorough introductory textbook for integrating psychotropic drug prescribing into psychological practices. It covers basic concepts in physiology, neurology, and pharmacology in easily understood language. Not only is this book a requirement for any psychologist seeking to gain prescriptive authority, but it is also helpful for any mental health clinician who collaborates with prescribers of any discipline. I recommend it highly." Daniel Carlat, MD, Editor in Chief of The Carlat Psychiatry Report "An important resource for any psychologist who is preparing to become a prescribing psychologist or for any psychologist who wants to be informed about the practice of medical psychology." Joseph E. Comaty, PhD, MP, coauthor of A Primer of Drug Action "Handbook of Clinical Psychopharmacology for Psychologists is an excellent treatise written by psychologists for psychologists." From the Foreword by Patrick H. DeLeon, PhD, and Jack G. Wiggins, PhD, former presidents of the American Psychological Association An essential and practical guide to integrating psychopharmacology into clinical practice Edited by medical psychologists with contributions by notable experts in their respective specialties, Handbook of Clinical Psychopharmacology for Psychologists covers key topics including: Ethics, standards of care, laws, and regulations relevant to clinical psychopharmacology Disorders of the nervous system, with particular relevance to psychopharmacology Use of comprehensive diagnostic strategies to establish differential diagnoses among possible medical and psychological symptoms Integration of pharmacotherapy with psychotherapy This essential book also provides an introduction to the qualifying exam for psychologists seeking specialty training in psychopharmacology, the Psychopharmacology Exam for Psychologists (PEP). The PEP-like practice test is available on the companion CD-ROM.