A Practical Guide To The Histology Of The Mouse

Author : Cheryl L. Scudamore
Publisher : John Wiley & Sons
Page : 258 pages
File Size : 44,5 Mb
Release : 2014-02-10
Category : Medical
ISBN : 9781119941200

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A Practical Guide to the Histology of the Mouse by Cheryl L. Scudamore Pdf

A Practical Guide to the Histology of the Mouse provides a full-colour atlas of mouse histology. Mouse models of disease are used extensively in biomedical research with many hundreds of new models being generated each year. Complete phenotypic analysis of all of these models can benefit from histologic review of the tissues. This book is aimed at veterinary and medical pathologists who are unfamiliar with mouse tissues and scientists who wish to evaluate their own mouse models. It provides practical guidance on the collection, sampling and analysis of mouse tissue samples in order to maximize the information that can be gained from these tissues. As well as illustrating the normal microscopic anatomy of the mouse, the book also describes and explains the common anatomic variations, artefacts associated with tissue collection and background lesions to help the scientist to distinguish these changes from experimentally- induced lesions. This will be an essential bench-side companion for researchers and practitioners looking for an accessible and well-illustrated guide to mouse pathology. Written by experienced pathologists and specifically tailored to the needs of scientists and histologists Full colour throughout Provides advice on sampling tissues, necropsy and recording data Includes common anatomic variations, background lesions and artefacts which will help non-experts understand whether histologic variations seen are part of the normal background or related to their experimental manipulation

Author : Gunasegaran
Publisher : Elsevier India
Page : 428 pages
File Size : 52,9 Mb
Release : 2007
Category : Histology
ISBN : 8131203514

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Textbook Of Histology And A Practical Guide by Gunasegaran Pdf

Author : Piper M. Treuting,Suzanne M. Dintzis,Kathleen S. Montine
Publisher : Academic Press
Page : 570 pages
File Size : 48,8 Mb
Release : 2017-08-29
Category : Science
ISBN : 9780128029190

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Comparative Anatomy and Histology by Piper M. Treuting,Suzanne M. Dintzis,Kathleen S. Montine Pdf

The second edition of Comparative Anatomy and Histology is aimed at the new rodent investigator as well as medical and veterinary pathologists who need to expand their knowledge base into comparative anatomy and histology. It guides the reader through normal mouse and rat anatomy and histology using direct comparison to the human. The side by side comparison of mouse, rat, and human tissues highlight the unique biology of the rodents, which has great impact on the validation of rodent models of human disease. Offers the only comprehensive source for comparing mouse, rat, and human anatomy and histology through over 1500 full-color images, in one reference work Enables human and veterinary pathologists to examine tissue samples with greater accuracy and confidence Teaches biomedical researchers to examine the histologic changes in their model rodents Experts from both human and veterinary fields take readers through each organ system in a side-by-side comparative approach to anatomy and histology - human Netter anatomy images along with Netter-style rodent images

Author : Piper M. Treuting,Suzanne M. Dintzis,Charles W. Frevert,Denny Liggitt,Kathleen S. Montine
Publisher : Academic Press
Page : 475 pages
File Size : 44,9 Mb
Release : 2012
Category : Medical
ISBN : 9780123813619

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Comparative Anatomy and Histology by Piper M. Treuting,Suzanne M. Dintzis,Charles W. Frevert,Denny Liggitt,Kathleen S. Montine Pdf

1. Introduction -- 2. Phenotyping -- 3. Necropsy and histology -- 4. Mammary Gland -- 5. Skeletal System -- 6. Nose, sinus, pharynx and larynx -- 7. Oral cavity and teeth -- 8. Salivary glands -- 9. Respiratory -- 10. Cardiovascular -- 11. Upper GI -- 12. Lower GI -- 13. Liver and gallbladder -- 14. Pancreas -- 15. Endocrine System -- 16. Urinary System -- 17. Female Reproductive System -- 18. Male Reproductive System -- 19. Hematopoietic and Lymphoid Tissues -- 20. Nervous System -- 21. Special senses, eye -- 22. Special senses, ear -- 23. Skin and adnexa -- Index.

Author : Adriaan Jacobus Reinecke,S. A. Viljoen
Publisher : Unknown
Page : 35 pages
File Size : 51,8 Mb
Release : 1993
Category : Histology
ISBN : OCLC:668333576

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Introduction to Histology by Adriaan Jacobus Reinecke,S. A. Viljoen Pdf

Author : Hannsjörg Schröder,Natasha Moser,Stefan Huggenberger
Publisher : Springer Nature
Page : 353 pages
File Size : 49,7 Mb
Release : 2020-02-28
Category : Medical
ISBN : 9783030198985

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Neuroanatomy of the Mouse by Hannsjörg Schröder,Natasha Moser,Stefan Huggenberger Pdf

This textbook describes the basic neuroanatomy of the laboratory mouse. The reader will be guided through the anatomy of the mouse nervous system with the help of abundant microphotographs and schemata. Learning objectives and summaries of key facts at the beginning of each chapter provide the reader with an overview on the most important information. As transgenic mice are one of the most widely used paradigms when it comes to modeling human diseases, a basic understanding of the neuroanatomy of the mouse is of considerable value for all students and researchers in the neurosciences and pharmacy, but also in human and veterinary medicine. Accordingly, the authors have included, whenever possible, comparisons of the murine and the human nervous system. The book is intended as a guide for all those who are about to embark on the structural, histochemical and functional phenotyping of the mouse’s central nervous system. It can serve as a practical handbook for students and early researchers, and as a reference book for neuroscience lectures and laboratories.

Author : Stephen R. Peters
Publisher : Springer Science & Business Media
Page : 194 pages
File Size : 49,5 Mb
Release : 2010-03-20
Category : Medical
ISBN : 9781441912343

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A Practical Guide to Frozen Section Technique by Stephen R. Peters Pdf

A Practical Guide to Frozen Section Technique offers an easy to learn approach to frozen section technique in the form of a highly illustrated handbook intended for onsite use in the laboratory. The book begins with a novel, clearly delineated, step by step approach to learning continuous motion brush technique. Emphasis is placed on recognizing and correcting artifacts during the preparation process. The book addresses all of the steps in the preparation of slides from cutting through cover-slipping. The author’s unique, original techniques for tissue embedding including face down embedding in steel well bars, frozen block cryoembedding and paper cryoembedding are detailed. Variables key to the quality of the preparation including block temperature, tissue properties and section thickness are detailed. The book also covers understanding the cryostat and basic maintenance and care.Sections covering techniques used in Mohs dermatologic surgery, and techniques used in basic animal and human research are discussed by noted experts in their field. A Practical Guide to Frozen Section Technique will be of great value to pathologists, pathology residents in training and also experimental pathology researchers that rely upon this methodology to perform tissue analysis in research.

Author : Jesus Ruberte,Ana Carretero,Marc Navarro
Publisher : Elsevier
Page : 602 pages
File Size : 52,9 Mb
Release : 2017-01-27
Category : Medical
ISBN : 9780128128770

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Morphological Mouse Phenotyping by Jesus Ruberte,Ana Carretero,Marc Navarro Pdf

Morphological Mouse Phenotyping: Anatomy, Histology and Imaging is an atlas of explanatory diagrams and text that guides the reader through normal mouse anatomy, histology, and imaging. The book is targeted for mouse researchers and veterinarian and human pathologists, and presents a complete, integrative description of normal mouse morphology. Disease animal models are fundamental in research to improve human health. The success of using genetically engineered mice to evaluate molecular disease hypotheses has encouraged the development of massive global projects, making the mouse the most used animal disease model. Laboratory mouse populations are straining the housing capacity of pharmaceutical and biotechnology companies, as well as public research institutions. However, the scientific community lacks sufficient expertise in morphological phenotyping to effectively characterize and validate these animal models. The mouse displays fundamental morphological similarities to humans; however, a mouse is not a man. Features more than 2,200 original images showing the anatomy, histology, and cellular structure of mouse organs Includes images specifically produced for this book in the Mouse Imaging Platform (Center for Animal Biotechnology and Gene Therapy, Universitat Autònoma de Barcelona) Offers an integrative vision of mouse morphology using correlative X-ray, computed tomography, magnetic resonance, and ultrasound images Employs classical anatomical techniques such as conventional dissection, skeletal preparations, vascular injections, and histological, immunohistochemical, and electron microscopy techniques to characterize mouse morphology

Author : Kwok-Sui Leung,Wing-Hoi Cheung
Publisher : World Scientific
Page : 941 pages
File Size : 51,9 Mb
Release : 2008
Category : Health & Fitness
ISBN : 9789812794093

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A Practical Manual for Musculoskeletal Research by Kwok-Sui Leung,Wing-Hoi Cheung Pdf

This manual provides technical protocols for musculoskeletal research on a translational basis, i.e. a disease-orientated approach. It offers guidance on various laboratory techniques, including cell culture and molecular biology, histology and histomorphometry, microscopy and bioimaging, laboratory animal models, CT- and MRI-based densitometry and microarchitectural analysis, biomechanics and functional analysis of orthopedic kinesiology, etc. The content is simple and straightforward, with illustrations and step-by-step procedures as an easy experimental reference for personnel in basic and clinical musculoskeletal research and education. This book will provide a unique multidisciplinary platform for various professions OCo not only orthopedics, but also biomedical engineering and biomaterial sciences OCo involving both basic and clinical medicine."

Author : Stacey E. Mills
Publisher : Lippincott Williams & Wilkins
Page : 3002 pages
File Size : 47,9 Mb
Release : 2012-07-16
Category : Medical
ISBN : 9781451177800

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Histology for Pathologists by Stacey E. Mills Pdf

A strong grounding in basic histology is essential for all pathologists. However, there had always been a gap between histology and pathology in which histologic information specifically for the pathologist was often lacking. Histology for Pathologists deals with the microscopic features of normal human tissues, from the perspective of the surgical pathologist. This is the only text that uses human (vs. animal) tissues for the histology. It is the best reference in the literature for information on normal histology, and, as such, is essential for all clinical pathologists. Written by pathologists for pathologists, the new edition updates the pathologist's understanding of normal histology up to date with the incremental advances made in the last five years. The 3rd edition has become a "classic" purchased by virtually all residents beginning their pathology training, as well as pathologists in practice. The 4th edition builds on that substantial foundation. The table of contents remains essentially the same with the exception of some changes in authorship.

Author : Elizabeth McInnes
Publisher : John Wiley & Sons
Page : 210 pages
File Size : 55,7 Mb
Release : 2017-05-01
Category : Science
ISBN : 9781118755419

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Pathology for Toxicologists by Elizabeth McInnes Pdf

Non-pathologists, such as toxicologists and study personnel, can find it difficult to understand the data they receive from pathologists. Toxicological pathologists write long, detailed and highly technical reports. Study personnel are under daily pressure to decide whether lesions described in pathology reports are treatment-related and thus important to the pharmaceutical company or whether the lesions are background changes and thus of little significance. Written by experienced toxicological pathologists, Pathology for Toxicologists: Principles and Practices of Laboratory Animal Pathology for Study Personnel serves to bridge the gap in the understanding of pathology data, enabling non-pathologists to more easily comprehend pathology reports, better integrate pathology data into final study reports and ask pathologists relevant questions about the test compound. This succinct, fully referenced, full colour book is suitable for toxicologists at all stages of their training or career who want to know more about the pathology encountered in laboratory animals used in safety studies. Key features include important chapters on spontaneous and target organ lesions in rats, mice, non-human primates, mini pigs, rabbits and beagle dogs as well as information on general pathology, macroscopic target organ lesions, ancillary pathology techniques, haematology, biochemistry and adversity. Pathology for Toxicologists: Principles and Practices of Laboratory Animal Pathology for Study Personnel includes: Colour diagrams explaining how lesions are caused by either external compounds or spontaneously The anatomic variations and background lesions of laboratory animals Advice on sampling tissues, necropsy, ancillary pathology techniques and recording data A chapter on the haematology and biochemistry of laboratory animals Full colour photographs of common macroscopic lesions encountered in laboratory animals A comprehensive glossary

Author : T. Yee Khong,Eoghan E. Mooney,Peter G. J. Nikkels,Terry K. Morgan,Sanne J. Gordijn
Publisher : Springer
Page : 395 pages
File Size : 40,6 Mb
Release : 2018-12-24
Category : Medical
ISBN : 9783319972145

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Pathology of the Placenta by T. Yee Khong,Eoghan E. Mooney,Peter G. J. Nikkels,Terry K. Morgan,Sanne J. Gordijn Pdf

This book provides a comprehensive resource on the pathology of the human singleton placenta. Agreed nomenclature, nosology, definitions and, where possible, thresholds for meaningful clinical corrections for lesions ideal for practical application in clinical practice are presented. Evidence is also featured on relevant potential clinical correlations to aid the reader in deciding upon the most appropriate management strategy. Areas of current uncertainty are also covered for potential future research. Pathology of the Placenta systematically describes placental pathology, and represents a valuable resource for practising and trainee pathologists, obstetricians, neonatologists and epidemiologists.

Author : Yuehuei H. An,Kylie L. Martin
Publisher : Springer Science & Business Media
Page : 588 pages
File Size : 47,9 Mb
Release : 2003-05-01
Category : Medical
ISBN : 9781592594177

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Handbook of Histology Methods for Bone and Cartilage by Yuehuei H. An,Kylie L. Martin Pdf

Histotechnology and histomorphometry are the major methodologies in bone and cartila- related research. Handbook of Histology Methods for Bone and Cartilage is an outgrowth of the editors’ own quest for information on bone and cartilage histology and histomorphometry. It is designed to be an experimental guide for personnel who work in the areas of basic and clinical bone and cartilage, orthopedic, or dental research. It is the first inclusive and organized reference book on histological and histomorphometrical techniques on bone and cartilage specimens. The topic has not previously been covered adequately by any existing books in the field. Handbook of Histology Methods for Bone and Cartilage has six major parts and is designed to be concise as well as inclusive, and more practical than theoretical. The text is simple and straightforward. Large numbers of tables, line drawings, and micro- or macro-photographs, are used to help readers better understand the content. Full bibliographies at the end of each chapter guide readers to more detailed information. A book of this length cannot discuss every method for bone and cartilage histology that has been used over the years, but it is hoped that major methods and their applications have been included.

Author : Hans Hedrich
Publisher : Academic Press
Page : 868 pages
File Size : 44,7 Mb
Release : 2012-06-14
Category : Science
ISBN : 9780123820099

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The Laboratory Mouse by Hans Hedrich Pdf

The Laboratory Mouse, Second Edition is a comprehensive book written by international experts. With inclusions of the newly revised European standards on laboratory animals, this will be the most current, global authority on the care of mice in laboratory research. This well-illustrated edition offers new and updated chapters including immunology, viruses and parasites, behavior, enrichment and care standards of laboratory mice across the life sciences, medical and veterinary fields. Features four-color illustrations with complete instruction on mouse surgery, anatomy, behavior and care of the mouse in laboratory research Offers additional chapters on new mouse strains, phenotyping of strains, bacteria and parasites, and immunology Includes the newly revised EU standards on care, as well as, comparisons to standards and regulations in the US and other countries

Author : Brad Bolon
Publisher : CRC Press
Page : 446 pages
File Size : 53,9 Mb
Release : 2015-04-24
Category : Medical
ISBN : 9781420070095

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Pathology of the Developing Mouse by Brad Bolon Pdf

Pathology of the Developing Mouse provides, in so far as feasible, one complete reference on the design, analysis, and interpretation of abnormal findings that may be detected in developing mice before and shortly after birth. In particular, this book is designed specifically to be not only a "how to do" manual for developmental pathology experimentation in mice but, more importantly, a "how to interpret" resource for pathologists and other biomedical scientists faced for the first or hundredth time with defining the significance of distorted features in some fantastic murine developmental monstrosity. The topics covered in this volume include a full range of subjects encountered when building and wielding a developmental pathology tool kit: baseline anatomic and physiologic traits of developing mice principles of good experimental design and statistical analysis for mouse developmental pathology studies procedures for anatomic pathology examinations, to evaluate structural changes at the macroscopic (gross), microscopic (cells and tissues), and ultrastructural (subcellular) levels, suing conventional autopsy-based or novel non-invasive imaging techniques; methods for clinical pathology testing, to assess the biochemical and cellular composition of tissues and fluids; options and protocols for in situ molecular pathology analysis, to undertake site-specific explorations of the various mechanisms responsible for producing adverse findings (i.e., "lesions") during development; and well-referenced and illustrated guides to the interpretation of anatomic pathology and clinical pathology changes in the animal (embryos, fetuses, neonates, and juveniles) and its support system (placenta).