Advanced Understanding Of Neurodegenerative Diseases

Author : Raymond Chuen-Chung Chang
Publisher : BoD – Books on Demand
Page : 458 pages
File Size : 45,5 Mb
Release : 2011-12-16
Category : Medical
ISBN : 9789533075297

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Advanced Understanding of Neurodegenerative Diseases by Raymond Chuen-Chung Chang Pdf

Advanced Understanding of Neurodegenerative Diseases focuses on different types of diseases, including Alzheimer's disease, frontotemporal dementia, different tauopathies, Parkinson's disease, prion disease, motor neuron diseases such as multiple sclerosis and spinal muscular atrophy. This book provides a clear explanation of different neurodegenerative diseases with new concepts of understand the etiology, pathological mechanisms, drug screening methodology and new therapeutic interventions. Other chapters discuss how hormones and health food supplements affect disease progression of neurodegenerative diseases. From a more technical point of view, some chapters deal with the aggregation of prion proteins in prion diseases. An additional chapter to discuss application of stem cells. This book is suitable for different readers: college students can use it as a textbook; researchers in academic institutions and pharmaceutical companies can take it as updated research information; health care professionals can take it as a reference book, even patients' families, relatives and friends can take it as a good basis to understand neurodegenerative diseases.

Author : Jeffrey L. Cummings,Jagan A. Pillai
Publisher : Oxford University Press
Page : 361 pages
File Size : 52,6 Mb
Release : 2016-11-14
Category : Medical
ISBN : 9780190233563

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Neurodegenerative Diseases by Jeffrey L. Cummings,Jagan A. Pillai Pdf

'Neurodegenerative Diseases' is the result of a conceptual revolution over the last decade in our understanding of neurodegenerative diseases as sharing unifying features. There is an increasing appreciation of the common biological and pathological features across seemingly varied neurodegenerative diseases that entail protein misfolding dysfunction and its consequences over time. Providing an overview of this conceptual change is the main theme for this work.

Author : Orla Hardiman,Colin P. Doherty
Publisher : Springer Science & Business Media
Page : 308 pages
File Size : 51,8 Mb
Release : 2011-06-15
Category : Medical
ISBN : 9781849960113

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Neurodegenerative Disorders by Orla Hardiman,Colin P. Doherty Pdf

Neurodegenerative Disorders provides an accessible guide to the commonest neurodegenerative diseases, outlining the main clinical features, treatment options and outcomes of the conditions most frequently encountered in clinical practice. Beginning with an overview of the general principles that underlie degeneration, and the contribution of established and new diagnostics techniques, the book goes on to describe the most common neurodegenerative conditions including Alzheimer Disease; Dementia and Cerebrovascular Disease; Parkinson’s Disease; Fronto-Temporal Dementia; Amyotrophic Lateral Sclerosis; Huntington’s Disease; Parkinsonism Plus syndromes and Prion Diseases. Final chapters cover important management issues including the use of palliative care strategies, advance directives and competence. Written by experts in the field internationally Neurodegenerative Disorders is a practical guide for clinicians that will be indispensable for the management of these conditions.

Author : Natalie Theresa
Publisher : Unknown
Page : 0 pages
File Size : 43,7 Mb
Release : 2015-02-21
Category : Electronic
ISBN : 1632411814

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Encyclopedia of Neurodegenerative Diseases: Volume VI (Advanced Researches) by Natalie Theresa Pdf

This book provides an extensive account of various diseases, such as Parkinson's disease, prion disease, motor neuron diseases like multiple sclerosis and spinal muscular atrophy. It also offers a profound explanation of various neurodegenerative diseases

Author : Donna J. Cross,Karina Mosci,Satoshi Minoshima
Publisher : Springer Nature
Page : 340 pages
File Size : 41,5 Mb
Release : 2023-09-26
Category : Medical
ISBN : 9783031350986

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Molecular Imaging of Neurodegenerative Disorders by Donna J. Cross,Karina Mosci,Satoshi Minoshima Pdf

This book provides a comprehensive review of the role of molecular imaging in neurodegenerative diseases. A growing field, molecular imaging of neurodegeneration is becoming increasingly relevant with an aging population, and this book serves to provide both an introduction to the concept and background of neurodegeneration and an update on the most recent imaging advances. Throughout, chapters will review current applications of neuroimaging in neurodegenerative disorders, like dementia and movement disorders, and increase knowledge of quantification and semi-quantification methods for neuroimaging. Imaging methods such as PET/CT and PET/MR are covered, as well as more advanced technologies like artificial intelligence algorithms and novel radiotracers. Chapters are also intended to improve competency in reporting and interpretation skills with structured information on current practice. The book concludes with a collection of up to date practice cases for the interpretation of neurodegeneration in nuclear medicine imaging. This is an ideal guide for nuclear medicine physicians, neuroradiologists, neurologists, residents, trainees, and related medical professionals caring for patients with neurodegeneration.

Author : Panagiotis Vlamos,Ilias S. Kotsireas,Ioannis Tarnanas
Publisher : Springer Nature
Page : 1031 pages
File Size : 52,9 Mb
Release : 2023-07-25
Category : Medical
ISBN : 9783319759227

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Handbook of Computational Neurodegeneration by Panagiotis Vlamos,Ilias S. Kotsireas,Ioannis Tarnanas Pdf

The Handbook of Computational Neurodegeneration provides a comprehensive overview of the field and thus bridges the gap between standard textbooks of research on neurodegeneration and dispersed publications for specialists that have a narrowed focus on computational methods to study this complicated process. The handbook reviews the central issues and methodological approaches related to the field for which the reader pursues a thorough overview. It also conveys more advanced knowledge, thus serving both as an introductory text and as a starting point for an in-depth study of a specific area, as well as a quick reference source for the expert by reflecting the state of the art and future prospects. The book includes topics that are usually missing in standard textbooks and that are only marginally represented in the specific literature. The broad scope of this handbook is reflected by five major parts that facilitate an integration of computational concepts, methods and applications in the study of neurodegeneration. Each part is intended to stand on its own, giving an overview of the topic and the most important problems and approaches, which are supported by examples, practical applications, and proposed methodologies. The basic concepts and knowledge, standard procedures and methods are presented, as well as recent advances and new perspectives.

Author : Sangam G. Kanekar
Publisher : Thieme
Page : 1574 pages
File Size : 41,5 Mb
Release : 2015-11-05
Category : Medical
ISBN : 9781604068559

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Imaging of Neurodegenerative Disorders by Sangam G. Kanekar Pdf

The definitive reference on imaging and diagnosis of neurodegenerative diseases FIVE STARS from Doody's Star Ratings™ Imaging of Neurodegenerative Disorders is a comprehensive, up-to-date reference covering the latest techniques used in neuroimaging as well as the basic structural imaging that facilitates diagnosis of various neurodegenerative disorders. All advanced imaging modalities, including MR spectroscopy, DTI, MRI, and PET scans, are discussed in detail, enabling readers to gain a solid understanding of how to use them to diagnose neurodegenerative diseases. Key Features: Each chapter covers the clinical features, pathology, and imaging of a specific disease/disorder Sections on cerebellar degeneration and dysfunction, motor neuron disorders, post-traumatic cognitive disorders, dementia with extrapyramidal syndromes, and deep brain stimulation A final section discusses the distinctions between preventable, potentially reversible, and irreversible dementia This book provides radiologists and all who care for patients suffering from neurodegenerative diseases with an invaluable reference that will be part of their medical library for many years to come.

Author : Uday Kishore
Publisher : BoD – Books on Demand
Page : 642 pages
File Size : 50,7 Mb
Release : 2013-05-15
Category : Medical
ISBN : 9789535110880

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Neurodegenerative Diseases by Uday Kishore Pdf

This book highlights the pathophysiological complexities of the mechanisms and factors that are likely to be involved in a range of neuroinflammatory and neurodegenerative diseases including Alzheimer's disease, other Dementia, Parkinson Diseases and Multiple Sclerosis. The spectrum of diverse factors involved in neurodegeneration, such as protein aggregation, oxidative stress, caspases and secretase, regulators, cholesterol, zinc, microglia, astrocytes, oligodendrocytes, etc, have been discussed in the context of disease progression. In addition, novel approaches to therapeutic interventions have also been presented. It is hoped that students, scientists and clinicians shall find this very informative book immensely useful and thought-provoking.

Author : Natalie Theresa
Publisher : Unknown
Page : 0 pages
File Size : 51,7 Mb
Release : 2015-02-21
Category : Electronic
ISBN : 1632411806

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Encyclopedia of Neurodegenerative Diseases: Volume V (Advanced Topics) by Natalie Theresa Pdf

This book targets various diseases, such as Alzheimer's disease, frontotemporal dementia and various tauopathies. It also provides a profound explanation of various neurodegenerative diseases with novel theories of understanding the etiology, pathological

Author : Anthony Schapira,Zbigniew K. Wszolek,Ted M. Dawson,Nicholas Wood
Publisher : John Wiley & Sons
Page : 344 pages
File Size : 44,6 Mb
Release : 2017-04-24
Category : Medical
ISBN : 9780470672686

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Neurodegeneration by Anthony Schapira,Zbigniew K. Wszolek,Ted M. Dawson,Nicholas Wood Pdf

This book unites the diverse range of complex neurodegenerative diseases into a textbook designed for clinical practice, edited by globally leading authorities on the subject. Presents a clinically oriented guide to the diseases caused by neurodegeneration Templated chapters combine clinical and research information on neurodegenerative diseases beginning with the common elements before treating each disease individually Diseases are grouped by anatomical regions of degeneration and include common disorders such as Parkinson’s Disease, Alzheimer’s Disease, Amyotrophic Lateral Sclerosis/Motor Neuron Disease, and Multiple Sclerosis as well as less common diseases Edited by globally leading authorities on the subject, and written by expert contributing authors

Author : Y. Mizuno,M. B. H. Youdim,D. B. Calne
Publisher : Unknown
Page : 296 pages
File Size : 53,7 Mb
Release : 2014-09-01
Category : Electronic
ISBN : 3709168457

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Advances in Research on Neurodegeneration by Y. Mizuno,M. B. H. Youdim,D. B. Calne Pdf

Author : Raymond Chuen-Chung Chang,Yuen-Shan Ho
Publisher : BoD – Books on Demand
Page : 104 pages
File Size : 52,7 Mb
Release : 2019-08-28
Category : Medical
ISBN : 9781789847369

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Neuroprotection by Raymond Chuen-Chung Chang,Yuen-Shan Ho Pdf

Neuroprotection is a strategy to prevent or delay the progression of chronic neurodegenerative diseases, acute neurological disorders, or even mental disorders. The major aim of this book is to focus on different approaches to achieve neuroprotection. In this book, there are chapters discussing imidazoline ligands and opioid ligands in Alzheimer's disease, the beneficial effects of adenosine A2A receptor antagonist, adrenergic receptor agonists and antagonists modulating microglial responses, and different approaches to achieve neuroprotection against aging-associated macular degeneration. This book will give insights to scientists in the field to stimulate their research, medical professionals to review their clinical practices, and others who would like to learn more about different neuroprotective approaches.

Author : Y. Mizuno,M.B.H. Youdim,D.B. Calne,R. Horowski,W. Poewe,P. Riederer
Publisher : Springer
Page : 0 pages
File Size : 43,6 Mb
Release : 1997-07-22
Category : Medical
ISBN : 3211829342

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Advances in Research on Neurodegeneration by Y. Mizuno,M.B.H. Youdim,D.B. Calne,R. Horowski,W. Poewe,P. Riederer Pdf

Neurodegeneration is one of the most important subjects of the investigation now and in the coming 21st century. Alzheimer's disease is the leading cause of dementia in the elderly people and Parkinson's disease is one of the major neurologic disorders with the prevalence between 1 and 2/1 000 population in advanced countries. Many others are suffering from intractable neurodegener ative disorders such as amyotrophic lateral sclerosis, Huntington's disease, or spinocerebellar degeneration. No truly effective treatment is available for any of these neurodegenerative disorders except for Parkinson's disease; even in Parkinson's disease, still it is impossible to slow down the disease process with the currently available treatment. It is urgently needed to develop new effective technique to halt or slow down the disease process in each of those disorders. Recent advance in the molecular biological and molecular genetic technique has brought us great progress in the understanding of etiology and pathogenesis of these disorders, but still it is not known how neurons are going to die in these disorders. To explore the question, mutual cooperation and exchange of ideas between basic scientists and clinical peoples are of utmost importance.

Author : M. Flint Beal,Anthony E. Lang,Albert C. Ludolph
Publisher : Cambridge University Press
Page : 1009 pages
File Size : 41,6 Mb
Release : 2005-06-02
Category : Medical
ISBN : 9781139443456

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Neurodegenerative Diseases by M. Flint Beal,Anthony E. Lang,Albert C. Ludolph Pdf

Neurodegenerative diseases are major contributors to disability and disease, with Alzheimer's and Parkinson's diseases the most prevalent. This major reference reviews the rapidly advancing knowledge of pathogenesis and treatment of neurodegenerative diseases in the context of a comprehensive survey of each disease and its clinical features. The editors and contributors are among the leading experts in the field internationally. Covering basic science, diagnostic tools and therapeutic approaches, the book focuses on all aspects of neurodegenerative disease, including the normal aging process. The dementias, prion diseases, Parkinson's disease and atypical parkinsonisms, neurodegenerative ataxias, motor neuron diseases, degenerative diseases with chorea, iron and copper disorders, and mitochondrial diseases, are all methodically presented and discussed, with extensive illustrations. In each case the underlying genetics, neuropathological and clinical issues are fully reviewed, making this the most complete as well as the most authoritative reference available to clinicians and neuroscientists.

Author : Dennis Dickson,Roy O. Weller
Publisher : John Wiley & Sons
Page : 497 pages
File Size : 54,7 Mb
Release : 2011-09-09
Category : Medical
ISBN : 9781444341232

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Neurodegeneration by Dennis Dickson,Roy O. Weller Pdf

Most textbooks on neurodegenerative disorders have used a classification scheme based upon either clinical syndromes or anatomical distribution of the pathology. In contrast, this book looks to the future and uses a classification based upon molecular mechanisms, rather than clinical or anatomical boundaries. Major advances in molecular genetics and the application of biochemical and immunocytochemical techniques to neurodegenerative disorders have generated this new approach. Throughout most of the current volume, diseases are clustered according to the proteins that accumulate within cells (e.g. tau, α-synuclein and TDP-43) and in the extracellular compartments (e.g. β-amyloid and prion proteins) or according to a shared pathogenetic mechanism, such as trinucleotide repeats, that are a feature of specific genetic disorders. Chapters throughout the book conform to a standard lay-out for ease of access by the reader and are written by a panel of International Experts Since the first edition of this book, major advances have been made in the discovery of common molecular mechanisms between many neurodegenerative diseases most notably in the frontotemporal lobar degenerations (FTLD) and motor neuron disease or amyotrophic lateral sclerosis. This book will be essential reading for clinicians, neuropathologists and basic neuroscientists who require the firm up-to-date knowledge of mechanisms, diagnostic pathology and genetics of Neurodegenerative diseases that is required for progress in therapy and management.