Advancing Therapeutic Development For Pain And Opioid Use Disorders Through Public Private Partnerships

Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Forum on Neuroscience and Nervous System Disorders
Publisher : National Academies Press
Page : 107 pages
File Size : 40,9 Mb
Release : 2018-06-22
Category : Medical
ISBN : 9780309473996

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Advancing Therapeutic Development for Pain and Opioid Use Disorders Through Public-Private Partnerships by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Forum on Neuroscience and Nervous System Disorders Pdf

Chronic pain is one of the most prevalent, costly, and disabling health conditions in the United States. Estimates show that more than 11 percent of the American population suffer from chronic pain, yet the federal pain research investment has been minimal. In parallel with a gradual increased recognition of the problems of treating chronic pain, the opioid epidemic has emerged as a growing public health emergency. The intersection of these two crises lies in the fact that an unintended consequence of treating pain has been an increasing number of opioid prescriptions and diversion of drugs for illicit purposes. In May 2017, the National Institutes of Health (NIH), and the National Institute on Drug Abuse announced a publicâ€"private partnership to develop solutions to the opioid crisis and cut in half the time it takes to develop non-addictive analgesics. To advance the planning of NIH's anticipated publicâ€"private partnerships, the National Academies' Forum on Neuroscience and Nervous Systems Disorders hosted a public workshop that brought together a diverse group of stakeholders from academia, federal agencies, advocacy organizations and companies developing therapeutics for pain and opioid use disorders. Participants discussed potential strategies to accelerate development of non-addictive pain medications and treatments for opioid use disorders. This publication summarizes the presentations and discussions from the workshop.

Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Forum on Neuroscience and Nervous System Disorders
Publisher : National Academies Press
Page : 107 pages
File Size : 48,8 Mb
Release : 2018-05-22
Category : Medical
ISBN : 9780309474023

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Advancing Therapeutic Development for Pain and Opioid Use Disorders Through Public-Private Partnerships by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Forum on Neuroscience and Nervous System Disorders Pdf

Chronic pain is one of the most prevalent, costly, and disabling health conditions in the United States. Estimates show that more than 11 percent of the American population suffer from chronic pain, yet the federal pain research investment has been minimal. In parallel with a gradual increased recognition of the problems of treating chronic pain, the opioid epidemic has emerged as a growing public health emergency. The intersection of these two crises lies in the fact that an unintended consequence of treating pain has been an increasing number of opioid prescriptions and diversion of drugs for illicit purposes. In May 2017, the National Institutes of Health (NIH), and the National Institute on Drug Abuse announced a publicâ€"private partnership to develop solutions to the opioid crisis and cut in half the time it takes to develop non-addictive analgesics. To advance the planning of NIH's anticipated publicâ€"private partnerships, the National Academies' Forum on Neuroscience and Nervous Systems Disorders hosted a public workshop that brought together a diverse group of stakeholders from academia, federal agencies, advocacy organizations and companies developing therapeutics for pain and opioid use disorders. Participants discussed potential strategies to accelerate development of non-addictive pain medications and treatments for opioid use disorders. This publication summarizes the presentations and discussions from the workshop.

Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Committee on Pain Management and Regulatory Strategies to Address Prescription Opioid Abuse
Publisher : National Academies Press
Page : 483 pages
File Size : 44,8 Mb
Release : 2017-09-28
Category : Medical
ISBN : 9780309459570

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Pain Management and the Opioid Epidemic by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Committee on Pain Management and Regulatory Strategies to Address Prescription Opioid Abuse Pdf

Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.

Author : Hilde Stevens,Michel Goldman
Publisher : Frontiers Media SA
Page : 107 pages
File Size : 45,7 Mb
Release : 2020-08-04
Category : Electronic
ISBN : 9782889639458

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Public-Private Partnerships as Drivers of Innovation in Healthcare, 2nd Edition by Hilde Stevens,Michel Goldman Pdf

Multi-stakeholder collaborations involving partners from public and private sectors are essential to address global health challenges and to move precision medicine forward. This eBook assembles a collection of papers which either illustrate recent achievements or discuss new perspectives offered by public-private partnerships in healthcare. Publisher’s note: In this 2nd edition, the following article has been added: Laverty H and Meulien P (2019) The Innovative Medicines Initiative −10 Years of Public-Private Collaboration. Front. Med. 6:275. doi: 10.3389/fmed.2019.00275

Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Global Health,Board on Health Sciences Policy,Global Forum on Innovation in Health Professional Education,Forum on Neuroscience and Nervous System Disorders
Publisher : National Academies Press
Page : 139 pages
File Size : 51,8 Mb
Release : 2019-05-23
Category : Medical
ISBN : 9780309490948

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The Role of Nonpharmacological Approaches to Pain Management by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Global Health,Board on Health Sciences Policy,Global Forum on Innovation in Health Professional Education,Forum on Neuroscience and Nervous System Disorders Pdf

Pain is a leading cause of disability globally. The dramatic increase in opioid prescriptions within the past decade in the United States has contributed to the opioid epidemic the country currently faces, magnifying the need for longer term solutions to treat pain. The substantial burden of pain and the ongoing opioid crisis have attracted increased attention in medical and public policy communities, resulting in a revolution in thinking about how pain is managed. This new thinking acknowledges the complexity and biopsychosocial nature of the pain experience and the need for multifaceted pain management approaches with both pharmacological and nonpharmacological therapies. The magnitude and urgency of the twin problems of chronic pain and opioid addiction, combined with the changing landscape of pain management, prompted the National Academies of Sciences, Engineering, and Medicine to convene a workshop on December 4â€"5, 2018, in Washington, DC. The workshop brought together a diverse group of stakeholders to discuss the current status of nonpharmacological approaches to pain management, gaps, and future directions. This publication summarizes the presentations and discussions from the workshop.

Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Committee on Medication-Assisted Treatment for Opioid Use Disorder
Publisher : National Academies Press
Page : 175 pages
File Size : 43,9 Mb
Release : 2019-06-16
Category : Medical
ISBN : 9780309486484

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Medications for Opioid Use Disorder Save Lives by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Committee on Medication-Assisted Treatment for Opioid Use Disorder Pdf

The opioid crisis in the United States has come about because of excessive use of these drugs for both legal and illicit purposes and unprecedented levels of consequent opioid use disorder (OUD). More than 2 million people in the United States are estimated to have OUD, which is caused by prolonged use of prescription opioids, heroin, or other illicit opioids. OUD is a life-threatening condition associated with a 20-fold greater risk of early death due to overdose, infectious diseases, trauma, and suicide. Mortality related to OUD continues to escalate as this public health crisis gathers momentum across the country, with opioid overdoses killing more than 47,000 people in 2017 in the United States. Efforts to date have made no real headway in stemming this crisis, in large part because tools that already existâ€"like evidence-based medicationsâ€"are not being deployed to maximum impact. To support the dissemination of accurate patient-focused information about treatments for addiction, and to help provide scientific solutions to the current opioid crisis, this report studies the evidence base on medication assisted treatment (MAT) for OUD. It examines available evidence on the range of parameters and circumstances in which MAT can be effectively delivered and identifies additional research needed.

Author : National Academies of Sciences, Engineering, and Medicine,Policy and Global Affairs,Committee on Science, Technology, and Law,Health and Medicine Division,Board on Health Sciences Policy,Forum on Neuroscience and Nervous System Disorders
Publisher : National Academies Press
Page : 81 pages
File Size : 42,5 Mb
Release : 2018-09-13
Category : Medical
ISBN : 9780309477796

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Neuroforensics by National Academies of Sciences, Engineering, and Medicine,Policy and Global Affairs,Committee on Science, Technology, and Law,Health and Medicine Division,Board on Health Sciences Policy,Forum on Neuroscience and Nervous System Disorders Pdf

Technological advances in noninvasive neuroimaging, neurophysiology, genome sequencing, and other methods together with rapid progress in computational and statistical methods and data storage have facilitated large-scale collection of human genomic, cognitive, behavioral, and brain-based data. The rapid development of neurotechnologies and associated databases has been mirrored by an increase in attempts to introduce neuroscience and behavioral genetic evidence into legal proceedings. In March 2018, the National Academies of Science, Engineering and Medicine organized a workshop in order to explore the current uses of neuroscience and bring stakeholders from neuroscience and legal societies together in both the United Kingdom and the United States. Participants worked together to advance an understanding of neurotechnologies that could impact the legal system and the state of readiness to consider these technologies and where appropriate, to integrate them into the legal system. This publication summarizes the presentations and discussions from the workshop.

Author : Institute of Medicine,Board on Health Sciences Policy,Committee on Advancing Pain Research, Care, and Education
Publisher : National Academies Press
Page : 383 pages
File Size : 55,7 Mb
Release : 2011-10-26
Category : Medical
ISBN : 9780309214841

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Relieving Pain in America by Institute of Medicine,Board on Health Sciences Policy,Committee on Advancing Pain Research, Care, and Education Pdf

Chronic pain costs the nation up to $635 billion each year in medical treatment and lost productivity. The 2010 Patient Protection and Affordable Care Act required the Department of Health and Human Services (HHS) to enlist the Institute of Medicine (IOM) in examining pain as a public health problem. In this report, the IOM offers a blueprint for action in transforming prevention, care, education, and research, with the goal of providing relief for people with pain in America. To reach the vast multitude of people with various types of pain, the nation must adopt a population-level prevention and management strategy. The IOM recommends that HHS develop a comprehensive plan with specific goals, actions, and timeframes. Better data are needed to help shape efforts, especially on the groups of people currently underdiagnosed and undertreated, and the IOM encourages federal and state agencies and private organizations to accelerate the collection of data on pain incidence, prevalence, and treatments. Because pain varies from patient to patient, healthcare providers should increasingly aim at tailoring pain care to each person's experience, and self-management of pain should be promoted. In addition, because there are major gaps in knowledge about pain across health care and society alike, the IOM recommends that federal agencies and other stakeholders redesign education programs to bridge these gaps. Pain is a major driver for visits to physicians, a major reason for taking medications, a major cause of disability, and a key factor in quality of life and productivity. Given the burden of pain in human lives, dollars, and social consequences, relieving pain should be a national priority.

Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Care Services,Committee on Evidence-Based Clinical Practice Guidelines for Prescribing Opioids for Acute Pain
Publisher : National Academies Press
Page : 223 pages
File Size : 42,9 Mb
Release : 2020-03-20
Category : Medical
ISBN : 9780309496872

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Framing Opioid Prescribing Guidelines for Acute Pain by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Care Services,Committee on Evidence-Based Clinical Practice Guidelines for Prescribing Opioids for Acute Pain Pdf

The opioid overdose epidemic combined with the need to reduce the burden of acute pain poses a public health challenge. To address how evidence-based clinical practice guidelines for prescribing opioids for acute pain might help meet this challenge, Framing Opioid Prescribing Guidelines for Acute Pain: Developing the Evidence develops a framework to evaluate existing clinical practice guidelines for prescribing opioids for acute pain indications, recommends indications for which new evidence-based guidelines should be developed, and recommends a future research agenda to inform and enable specialty organizations to develop and disseminate evidence-based clinical practice guidelines for prescribing opioids to treat acute pain indications. The recommendations of this study will assist professional societies, health care organizations, and local, state, and national agencies to develop clinical practice guidelines for opioid prescribing for acute pain. Such a framework could inform the development of opioid prescribing guidelines and ensure systematic and standardized methods for evaluating evidence, translating knowledge, and formulating recommendations for practice.

Author : Michael T. Compton, M.D., M.P.H.,Marc W. Manseau, M.D., M.P.H.
Publisher : American Psychiatric Pub
Page : 462 pages
File Size : 48,9 Mb
Release : 2018-12-31
Category : Medical
ISBN : 9781615371570

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The American Opioid Epidemic by Michael T. Compton, M.D., M.P.H.,Marc W. Manseau, M.D., M.P.H. Pdf

This book provides an in-depth look at clinical and public health approaches to this epidemic from both psychiatric and medical perspectives and gives mental health professionals the big picture necessary to understand the epidemic.

Author : Gerard Moeller,Mishka Terplan
Publisher : Oxford University Press
Page : 400 pages
File Size : 52,5 Mb
Release : 2020-09-17
Category : Medical
ISBN : 9780190920210

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Substance Use Disorders by Gerard Moeller,Mishka Terplan Pdf

Substance Use Disorders provides an overview of substance misuse and addresses the neurobiology, pharmacotherapy, and behavioural therapy management of substance use disorders from a clinical perspective. Examining the opioid epidemic to frame its discussion of the epidemiology of substance misuse, this book explores common barriers that prevent the implementation of effective treatment. Chapters discuss various aspects of substance use disorders, particularly opioids, alcohol, cannabis, and cocaine, to inform better conceptualization and management of these conditions. Part of the Primer On Psychiatry series, this book will provide a solid foundation for residents and fellows in psychiatry and addiction medicine and can also be used in clinical practice.

Author : Anonim
Publisher : Unknown
Page : 35 pages
File Size : 49,6 Mb
Release : 2018
Category : Opioid abuse
ISBN : OCLC:1099609592

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Facing Addiction in America: the Surgeon General's Spotlight on Opioids by Anonim Pdf

Author : Office of the Surgeon General,U.s. Department of Health and Human Services
Publisher : Createspace Independent Publishing Platform
Page : 420 pages
File Size : 45,8 Mb
Release : 2017-08-15
Category : Electronic
ISBN : 1974580628

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Facing Addiction in America by Office of the Surgeon General,U.s. Department of Health and Human Services Pdf

All across the United States, individuals, families, communities, and health care systems are struggling to cope with substance use, misuse, and substance use disorders. Substance misuse and substance use disorders have devastating effects, disrupt the future plans of too many young people, and all too often, end lives prematurely and tragically. Substance misuse is a major public health challenge and a priority for our nation to address. The effects of substance use are cumulative and costly for our society, placing burdens on workplaces, the health care system, families, states, and communities. The Report discusses opportunities to bring substance use disorder treatment and mainstream health care systems into alignment so that they can address a person's overall health, rather than a substance misuse or a physical health condition alone or in isolation. It also provides suggestions and recommendations for action that everyone-individuals, families, community leaders, law enforcement, health care professionals, policymakers, and researchers-can take to prevent substance misuse and reduce its consequences.

Author : U.S. Department of Health and Human Services
Publisher : Lulu.com
Page : 84 pages
File Size : 47,7 Mb
Release : 2019-11-23
Category : Reference
ISBN : 9781794763531

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Federal Guidelines for Opioid Treatment Programs by U.S. Department of Health and Human Services Pdf

The Federal Guidelines for Opioid Treatment Programs (Guidelines) describe the Substance Abuse and Mental Health Services Administration's (SAMHSA) expectation of how the federal opioid treatment standards found in Title 42 of the Code of Federal Regulations Part 8 (42 CFR � 8) are to be satisfied by opioid treatment programs (OTPs). Under these federal regulations, OTPs are required to have current valid accreditation status, SAMHSA certification, and Drug Enforcement Administration (DEA) registration before they are able to administer or dispense opioid drugs for the treatment of opioid addiction.

Author : Michael H. Ebert,Robert D. Kerns
Publisher : Cambridge University Press
Page : 507 pages
File Size : 42,7 Mb
Release : 2010-11-25
Category : Medical
ISBN : 9781139493543

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Behavioral and Psychopharmacologic Pain Management by Michael H. Ebert,Robert D. Kerns Pdf

Pain is the most common symptom bringing a patient to a physician's attention. Physicians training in pain medicine may originate from different disciplines and approach the field with varying backgrounds and experience. This book captures the theory and evidence-based practice of behavioral, psychotherapeutic and psychopharmacological treatments in modern pain medicine. The book's contributors span the fields of psychiatry, psychology, anesthesia, neurology, physical medicine and rehabilitation, and nursing. Thus the structure and content of the book convey the interdisciplinary approach that is the current standard for the successful practice of pain management. The book is designed to be used as a text for training fellowships in pain medicine, as well as graduate courses in psychology, nursing, and other health professions.