Adverse Drug Reactions And The Skin

Author : Neil H. Shear,Roni P. Dodiuk-Gad
Publisher : Springer
Page : 314 pages
File Size : 52,6 Mb
Release : 2018-10-19
Category : Medical
ISBN : 9789811314896

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Advances in Diagnosis and Management of Cutaneous Adverse Drug Reactions by Neil H. Shear,Roni P. Dodiuk-Gad Pdf

This resource guides prescribers, pharmacists, and regulators with an update on the recent expansion of basic and clinical knowledge that forms a framework for understanding cutaneous reactions. This understanding will lead, in turn, to better outcomes and decisions in treatment and management, both in the clinic and in the life cycle of drug development. The skin is a common target for adverse drug events and even mild rashes can be part of life-threatening syndromes. Patients and practitioners often face important decisions about therapy after a drug eruption, including treatment, cross-reactivity with future pharmaceuticals, genetic considerations and dealing with long-term sequelae after a reaction. An international team of experts and leaders in the field share their story and insights into the scientific details and relevant clinical context.

Author : Stephen Breathnach,H. Hintner
Publisher : Wiley-Blackwell
Page : 408 pages
File Size : 49,6 Mb
Release : 1992-11-10
Category : Medical
ISBN : 0632033495

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Adverse Drug Reactions and the Skin by Stephen Breathnach,H. Hintner Pdf

Adverse Drug Reactions and the Skin is a thoroughly modern and comprehensive text/atlas covering the side effects to the skin, from medications, and the dermatological and other internal adverse manifestations of medications used by dermatologists. Illustrated in full color, this major new work will enjoy wide use across a broad cross-section of the medical profession. This volume is divided into three major sections. The first deals with the incidence and mechanisms of drug adverse reactions. The second section discusses reaction patterns that are recognized as characteristic of cutaneous drug reactions to particular medications. The reaction patterns are fully discussed and the text is fully supported by wide use of full-color illustrations. Lists of the drugs most commonly implicated in the causation of these reactions are also included. The final section includes the drugs reported to have caused skin side-effects, in a systematic listing by therapeutic groups. This listing includes dermatological preparations. Thus, the reader is able to research information on skin changes potentially caused by a given drug, and also to determine which drugs cause a given clinical reaction pattern.

Author : Lars E. French
Publisher : Karger Medical and Scientific Publishers
Page : 255 pages
File Size : 54,7 Mb
Release : 2012
Category : Medical
ISBN : 9783805599702

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Adverse Cutaneous Drug Eruptions by Lars E. French Pdf

An indispensable tool for understanding, diagnosing and managing this common clinical problem The skin is one of the most frequently involved organs in adverse drug reactions. Occurring with an incidence of 1-5% for certain types of drugs, cutaneous drug eruptions are mostly benign in nature, and comprise the maculopapular type of eruption and urticaria. However, about one third of them require hospital treatment, leading to a considerable burden for the health care system. In this book, a selected group of experts provide an up-to-date, condensed and clinically relevant overview of the field of cutaneous drug eruptions, ranging from epidemiology and genetic predisposition to available therapeutic measures, including rapid drug desensitization. Reflecting the great progress made in recent years in this field, this publication will be a useful tool for a better understanding, diagnosis and management of cutaneous drug eruptions, not only for general physicians, dermatologists and clinical allergologists, but also for nurses and scientists.

Author : Kirsti Kauppinen,Kristiina Alanko,Matti Hannuksela,Howard I. Maibach
Publisher : CRC Press
Page : 206 pages
File Size : 46,8 Mb
Release : 2020-11-25
Category : Health & Fitness
ISBN : 9781000142341

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Skin Reactions to Drugs by Kirsti Kauppinen,Kristiina Alanko,Matti Hannuksela,Howard I. Maibach Pdf

Skin reactions to drugs are a ubiquitous problem-the most commonly observed drug sensitivity observed in a wide range of specialties. Skin Reactions to Drugs emphasizes the mechanisms and clinical and laboratory proof of a cause-and-effect relationship between drugs and adverse reactions. It discusses the technique of drug challenge, which has been extensively developed in Finland, but not commonly practiced in the rest of the world. In this textbook, 12 of the most common drug eruptions are described both clinically and histologically. It features a chapter on systemic contact dermatitis and also addresses cutaneous adverse drug reactions that appear in HIV-infected patients. 40 full-color photographs provide vivid examples of the reactions being discussed. A highly practical resource for practicing physicians and other health care workers, Skin Reactions to Drugs represents the platinum standard of research conducted on the causation of certain adverse reactions of skin.

Author : Jack Uetrecht
Publisher : Springer Science & Business Media
Page : 552 pages
File Size : 51,7 Mb
Release : 2009-12-18
Category : Medical
ISBN : 9783642006630

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Adverse Drug Reactions by Jack Uetrecht Pdf

This book provides the current state of knowledge of basic mechanisms of adverse drug reactions (ADRs). The main focus is on idiosyncratic drug reactions because they are the most difficult to deal with. It starts with a general description of the major targets for ADRs followed by a description of what are presently believed to be mediators and biochemical pathways involved in idiosyncratic drug reactions. There is also a description of several examples of ADRs that serve to illustrate specific aspects of ADR mechanisms. Eventually the book shows that ultimately better methods are needed to predict which drug candidates are likely to cause ADRs and which patients are at increased risk. But at present research seems to be far from this goal.

Author : Sanford M. Goldstein,Bruce U. Wintroub
Publisher : Lippincott Williams & Wilkins
Page : 164 pages
File Size : 43,8 Mb
Release : 1996
Category : Medical
ISBN : UOM:39015037321588

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Adverse Cutaneous Reactions to Medication by Sanford M. Goldstein,Bruce U. Wintroub Pdf

Author : Esen Özkaya,Kurtuluş Didem Yazganoğlu
Publisher : Springer
Page : 268 pages
File Size : 48,7 Mb
Release : 2014-11-15
Category : Medical
ISBN : 9781447165361

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Adverse Cutaneous Drug Reactions to Cardiovascular Drugs by Esen Özkaya,Kurtuluş Didem Yazganoğlu Pdf

Adverse cutaneous drug reactions (ACDR) are among the most frequent events in patients receiving drug therapy. Cardiovascular (CV) drugs are an important group of drugs with potential risk of developing ACDR especially in elderly as marketing of more new drugs and their prescription continue to increase. However, like with most other drugs the exact incidence of cutaneous side effects from CV drugs is difficult to estimate due to sporadic reporting. Moreover, a reliable designation of a certain drug as the cause of a certain type of reaction can rarely be made. Apart from the well-known angioedema/urticaria from ACE inhibitors, lichen planus / lichenoid reaction from beta adrenergic blockers and photosensitivity from thiazid diuretics, ACDR from CV drugs might be seen in a wide spectrum extending to rare but life-threatening conditions such as erythroderma, Stevens-Johnson syndrome, toxic epidermal necrolysis or drug hypersensitivity syndrome. In this comprehensive review, the reported types of ACDR to CV drugs will be discussed according to drug class and the type of dermatologic reaction with special emphasize on cross-reactions and the role of patch testing in diagnosis.

Author : Haur Yueh Lee,Daniel Creamer
Publisher : Springer Nature
Page : 347 pages
File Size : 40,6 Mb
Release : 2022-10-27
Category : Medical
ISBN : 9783031093883

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Drug Eruptions by Haur Yueh Lee,Daniel Creamer Pdf

Cutaneous adverse drug reactions are common and range from the benign to those which are life-threatening. The clinical presentation of these dermatoses is varied and many may mimic common skin conditions. Consequently, diagnosis in drug-induced skin disease is challenging and the treatment considerations are complex. This book aims to bridge the divide between dermatology and allergy by providing a comprehensive review on the pathomechanisms and clinical features of cutaneous adverse drug reactions. Broken up into three distinct sections: General Considerations, Reaction Patterns, and Special Drug Categories, these chapters cover the common and rare adverse skin reactions and provide information on recent advances - particularly immunopathology and pharmacogenetics - as well as highlighting new adverse drug signals and novel therapies. Drug Eruptions is a must-have resource for dermatologists, allergists, internal physicians and general practitioners.

Author : A. T. Florence,E. G. Salole
Publisher : Elsevier
Page : 134 pages
File Size : 47,5 Mb
Release : 2013-10-22
Category : Medical
ISBN : 9781483183626

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Formulation Factors in Adverse Reactions by A. T. Florence,E. G. Salole Pdf

Topics in Pharmacy, Volume 1: Formulation Factors in Adverse Reactions focuses on the important aspect of drug therapy—the nature of the dosage form or its ingredients that adversely influence therapeutic outcome. This book discusses the adverse reactions to formulation excipients, immunological basis of allergic reactions to drugs, and adverse reactions to parenteral medication. The influence of the shape and size of solid medicines on esophageal transit, and effects of the physical characteristics of formulations on adverse reactions are also deliberated. This volume is intended for senior undergraduate and postgraduate students in pharmacy, medicine, nursing and allied health sciences, and practitioners in the field of drug therapy.

Author : Patricia Illing,Michael R. Ardern-Jones,Nicole Andrea Mifsud,Jason Trubiano
Publisher : Frontiers Media SA
Page : 176 pages
File Size : 40,8 Mb
Release : 2022-03-14
Category : Science
ISBN : 9782889746699

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The Immunology of Adverse Drug Reactions by Patricia Illing,Michael R. Ardern-Jones,Nicole Andrea Mifsud,Jason Trubiano Pdf

Author : Amanda Oakley
Publisher : Scion Publishing Ltd
Page : 438 pages
File Size : 48,5 Mb
Release : 2017-05-06
Category : Medical
ISBN : 9781911510116

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Dermatology Made Easy by Amanda Oakley Pdf

A concise overview of the common dermatological conditions most likely to present in general medicine From reviews: "... a perfect solution to the constant struggle that dermatology diagnosis presents to primary care physicians and other providers... This well-formatted book covers a vast array of topics ranging from common to rare skin disorders. The pictures are immensely helpful in the understanding of various skin rashes...." Fam Med 2019;51(5):451–452. “... easy to read and informative. One cannot emphasise enough the quality and comprehensive nature of the photographic content.... As someone who was interested in dermatology even as a medical student my only regret is that this book was not around when I was a student as it would have very adequately guided me into my beloved subspecialty.” Ulster Med J 2017;86(3):1–1. “The introduction outlines dermatological conditions by symptom, morphology and body site, providing an excellent index prior to delving into greater detail in the following chapters. The logical approach and level of detail make this text perfect for medical students, interns/residents, primary care physicians and other specialists who wish to quickly identify differential diagnoses or refresh their knowledge of dermatological conditions.” A Lecturer in Dermatology Dermatology Made Easy is based on the hugely popular DermNet New Zealand website and is designed to help GPs, medical students and dermatologists diagnose skin conditions with confidence. The book starts by providing a series of comprehensive tables, complete with over 500 thumbnail photos, to aid diagnosis according to symptoms, morphology, or body site. Once you have narrowed down the diagnosis, cross-references then guide you to more detailed descriptions, and another 700 photographs, covering: common infections inflammatory rashes non-inflammatory conditions skin lesions Every section provides consistent information on the disorder: who gets it and what causes it? what are the clinical features and does it cause any complications? how do you diagnose it? how do you treat it and how long does it take to resolve? The book concludes with a comprehensive section on further investigations and treatment options. Dermatology Made Easy combines the essential focus of the Made Easy book series with the authority and knowledge base of DermNet New Zealand’s unparalleled resources. Printed in full colour throughout.

Author : John C. Hall,Brian J. Hall
Publisher : Springer
Page : 463 pages
File Size : 47,9 Mb
Release : 2015-08-21
Category : Medical
ISBN : 9781447167297

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Cutaneous Drug Eruptions by John C. Hall,Brian J. Hall Pdf

​The burden of cutaneous drug reactions is significant, in both outpatient and inpatient settings, and can result in morbidity and even mortality. This book is unique in its approach to this problem. This text is divided into basic principles, common drug reactions, skin conditions mimicked by drug reactions, drug reactions to the skin appendages, life-threatening drug reactions, less common drug reactions, and special groupings of drug reactions. For the clinician, the skin can only morphologically react in to many limited ways. This is also true for the pathologist. Combining these two forever linked specialties is a synergistic paradigm that greatly enhances diagnosis, and ultimately therapy, for these pernicious conditions. Drug reactions in the skin remain a common complication of therapy. True incidences of drug reactions are not available. For general discussion, the rule of 3% can be applied with reasonable assuredness. Approximately 3% of all hospitalized patients develop an adverse cutaneous drug reaction. Approximately 3% of these reactions are considered severe. Outpatient data is even more obscure, but at least 3% of dermatology clinic outpatient visits are due to a drug reaction. Cutaneous drug reactions compromise approximately 3% of all drug reactions. Even more challenging is the fact that the most vulnerable populations to drug reactions are increasing and include the elderly patients on prolonged drug therapy, and patients that use multiple drugs at the same time.

Author : David Khan,Aleena Banerji
Publisher : Elsevier Health Sciences
Page : 250 pages
File Size : 48,6 Mb
Release : 2017-07-05
Category : Medical
ISBN : 9780323497077

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Drug Allergy Testing by David Khan,Aleena Banerji Pdf

With a focus on improving diagnosis and treatment, Drug Allergy Testing is your new go-to resource for understanding various drug allergies and testing methods, the epidemiology of and economic impact of drug allergies, and new drug and allergy developments. Features a wealth of up-to-date information for allergists, immunologists, and primary care physicians who diagnose and treat patients with drug allergies and hypersensitivity. Covers the basics of drug allergy evaluation and management as well as specific drugs including antibiotics, ASA/NSAIDs, chemotherapeutic agents and monoclonal antibodies.

Author : Heng Leong Chan
Publisher : Unknown
Page : 140 pages
File Size : 41,6 Mb
Release : 2000
Category : Dermatopharmacology
ISBN : 9814045519

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Cutaneous Adverse Drug Reactions by Heng Leong Chan Pdf

Author : Anne Lee
Publisher : Unknown
Page : 316 pages
File Size : 44,9 Mb
Release : 2001
Category : Drugs
ISBN : UOM:39015049732152

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Adverse Drug Reactions by Anne Lee Pdf

This guide to adverse drug reactions to medicines explains their likely frequency and severity, their predictability and reversability, predisposing factors and how to recognize and prevent them. Each chapter describes a specific group of adverse effects and contains case studies and tables.