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Anticholinesterase Pesticides by Tetsuo Satoh,Ramesh C. Gupta Pdf
This book offers an important reference source about the most common classes of pesticides for researchers engaged in the area of neurotoxicology, metabolism, and epidemiology. The book presents details about thorough characterization of target and non-target enzymes and proteins involved in toxicity and metabolism; and epidemiology of poisonings and fatalities in people from short- and long- term exposures to these pesticides in different occupational settings on an individual country basis as well as on a global basis. The early portion of the book deals with metabolism, mechanisms and biomonitoring of anticholinesterase pesticides, while the later part deals with epidemiological studies, regulatory issues, and therapeutic intervention.
Toxicology of Organophosphate and Carbamate Compounds by Ramesh C. Gupta Pdf
This text/reference book provides the most comprehensive coverage of anticholinesterase compounds (Organophosphates and Carbamates), which constitute the largest number of chemicals that are primarily used as insecticides in agriculture, industry, and around the home/garden. Some OPs (nerve agents) have been used in chemical warfare and terrorist attacks, while some OPs and CMs have been recommended as therapeutic agents in human medicine as well as in veterinary medicine. Many chemicals of both classes are extremely toxic and lack selectivity, thus their inadvertent/accidental use continues to pose a threat to human and animal health, aquatic systems and wildlife. These anticholinesterase agents produce a variety of toxicological effects in target and nontarget organs. In light of this complexicity, this multi-authored book is written by the well known scientists from many countries. The book is organized into nine sections, with a total of 49 chapters, to provide in-depth knowledge on various aspects of OP and CM compounds, including their use, classification, mechanism-based toxicity, and prophylactic and therapeutic measurements. Several chapters are written with special emphasis to cover timely topics, such as chemical warfare agents, physiologically-based pharmacokinetic modeling, structure and function of cholinesterases, paraoxonase, carboxylesterases; developmental neurotoxicity, the intermediate syndrome, oxidative stress, endocrine disruption, and DNA damage/gene expression and carcinogenesis. Section-VI with 5 chapters is specifically devoted to risk assessment, and safety and regulatory guidelines for pesticides. Describes everything you need to know about Organophosphates and Carbamates Extensively covers pesticides, nerve agents, therapeutic drugs, and flame retardants Describes epidemiology of the world's major disasters involving Organophosphates and Carbamates Covers animal, human, aquatic, and wildlife toxicity of Anticholinesterases Insights into in-depth cholinergic and noncholinergic mechanisms of toxicity Describes recent advancements in cholinesterases, paraoxonases, carboxylesterases, oxidative stress, endocrine disruption, cardiac and pulmonary toxicity, and carcinogenesis Provides in vitro and in vivo models for neurotoxicity testing Integrates knowledge of studies in lab animals and humans Offers risk/safety assessment and national/international guidelines for permissible levels of pesticide residues Describes management of Anticholinesterase poisoning in humans
Cholinesterase-inhibiting Insecticides by Pierre Mineau Pdf
Foremost specialists in the field of cholinesterase-inhibiting insecticides have contributed to this volume, to provide an accurate assessment of the impacts of organophosphate and carbamate pesticides on non-target organisms, especially wildlife. The increased scrutiny of pest control agents in recent years has resulted from several factors. These comprise the demands for environmental protection, the recognition of wildlife as a valuable and diminishing resource, and the realization that few wild habitats exist that pest control programs do not directly target or indirectly affect. In that context, the book brings together the scattered literature on the effects of anticholinesterase pesticides on wildlife and other non-target species. The literature has long been dominated by research emanating from the drug industry and the military. The therapeutic aspects of cholinergically-active substances and their potential as chemical warfare agents has directed research in the field. Thus the measurement of cholinesterase activity as a biomarker to assess the impact on wildlife species is a relatively recent phenomenon.
Handbook of Pesticides by Leo M.L. Nollet,Hamir S. Rathore Pdf
This handbook provides a systematic description of the principles, procedures, and technology of the modern analytical techniques used in the detection, extraction, clean up, and determination of pesticide residues present in the environment. This book provides the historical background of pesticides and emerging trends in pesticide regulation. The
In order to get a general concept of organophosphorus pesticides with such a variety in structure and biological activities, consideration of each aspect of chemistry, biochemistry, and the applied sciences is necessary. This book consists of these three main parts. After the presentation of the background of phosphorus chemistry in Chapter 1, stress was put on the chemical and biochemical reactions of organophosphorus pesticides, including synthesis, analysis, metabolism mode of action, and other interesting aspects in Chapter 2 to 4, and on the structure-pesticidal activity relationship in Chapter 5.
Mammalian Toxicology of Insecticides by Tim Marrs Pdf
Insects more similar in structure and physiology to mammals than plants or fungi. Consequently, insecticides are often of greater toxicity to mammals than herbicides. This is particularly the case with neurotoxins. However, some insecticides are targeted at structures or hormonal systems specific to insects (insect growth regulators/chitin synthesis inhibitors) so are less harmful but can still be mildly haematotoxic. There are, therefore, issues specific to insecticides, which do not occur with other pesticides - hence the need for a book specifically on insecticide toxicology in mammals. The book starts with general issues relating to the mammalian toxicity of insecticides, including target/non-target specificity, nomenclature and metabolism of insecticides. It then goes on to discuss specific types of insecticide including: organochlorines; anticholinesterases; pyrethrum and synthetic pyrethroids; nicotine and the neonicotinoids; insect growth regulators/ecdysone agonists/chitin synthesis inhibitors; insecticides of natural origin; biological insecticides; and insecticides used in veterinary medicine.
Peter Cameron,George Jelinek,Anne-Maree Kelly,Lindsay Murray,Anthony F. T. Brown
Author : Peter Cameron,George Jelinek,Anne-Maree Kelly,Lindsay Murray,Anthony F. T. Brown Publisher : Elsevier Health Sciences Page : 1047 pages File Size : 51,9 Mb Release : 2011-11-18 Category : Medical ISBN : 9780702049316
Textbook of Adult Emergency Medicine E-Book by Peter Cameron,George Jelinek,Anne-Maree Kelly,Lindsay Murray,Anthony F. T. Brown Pdf
A major postgraduate textbook in emergency medicine, covering all the major topics that present to the trainee doctor in the emergency department. A comprehensive textbook of adult emergency medicine for trainee doctors - covers all the problems likely to present to a trainee in the emergency department. Chapters are short and concise, with key point boxes (called "Essentials") at the beginning. Also has boxes featuring controversial areas of treatment. Practical and clinically orientated. Major changes to resuscitation guidelines. Complete rewriting of ENT section. Significant updating of following topics - acute coronary syndrome management, trauma, sepsis management, imaging, arrhythmias. Expansion of administration section - especially patient safety. Changes to drug overdose sections in toxicology section.
Pesticide Toxicology and International Regulation by Timothy T. Marrs,Bryan Ballantyne Pdf
Dieser Band gehört zur bekannten Wiley-Reihe 'Current Toxicology Series' und befasst sich ausführlich mit der Pestizidtoxikologie. Untersucht werden Pestizide nach Gruppen (z. B. Insektizide und Fungizide), ihre Rückstände in Lebensmitteln sowie die Metabolisierung von Pestiziden. Darüber hinaus werden berufsbezogene Aspekte und die Behandlung von Vergiftungserscheinungen umfassend diskutiert. "Pesticide Toxicology" ist das erste einbändige Werk zum Thema Pestizide, das spezialisierte und dennoch umfassende Informationen sowohl für Experten als auch für Doktoranden bereit hält. Herausgeber Timothy Marrs ist ein international anerkannter Experte in der Pestizidforschung und genießt großes Ansehen auf dem Gebiet der Toxikologie. Geschrieben wurde der Band von einem Team international renommierterToxikologen.
United States. Department of Health, Education, and Welfare. Secretary's Commission on Pesticides and Their Relationship to Environmental Health
Author : United States. Department of Health, Education, and Welfare. Secretary's Commission on Pesticides and Their Relationship to Environmental Health Publisher : Unknown Page : 712 pages File Size : 55,8 Mb Release : 1969 Category : Pesticides ISBN : IND:30000100139108
Report of the Secretary's Commission on Pesticides and Their Relationship to Environmental Health by United States. Department of Health, Education, and Welfare. Secretary's Commission on Pesticides and Their Relationship to Environmental Health Pdf
